Adcy1 (adenylate cyclase 1) - Rat Genome Database

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Gene: Adcy1 (adenylate cyclase 1) Rattus norvegicus
Analyze
Symbol: Adcy1
Name: adenylate cyclase 1
RGD ID: 1309318
Description: Enables calcium- and calmodulin-responsive adenylate cyclase activity. Involved in cAMP biosynthetic process; circadian rhythm; and response to xenobiotic stimulus. Located in axon hillock; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 44. Orthologous to human ADCY1 (adenylate cyclase 1); PARTICIPATES IN endothelin signaling pathway; G protein mediated signaling pathway via Galphas family; protein kinase A (PKA) signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ac1; adenylate cyclase 1 (brain); adenylate cyclase type 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81486,125,119 - 86,234,459 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1486,124,850 - 86,261,075 (+)EnsemblGRCr8
mRatBN7.21481,911,240 - 82,020,594 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,911,099 - 82,028,969 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1486,312,501 - 86,421,804 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,552,335 - 87,661,649 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01484,001,921 - 84,110,208 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01487,311,970 - 87,429,880 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1487,312,203 - 87,421,659 (+)Ensemblrn6Rnor6.0
Rnor_5.01480,947,153 - 81,055,801 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41487,812,256 - 87,923,402 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1480,985,818 - 81,095,021 (+)NCBICelera
RGSC_v3.11487,831,237 - 87,942,547 (+)NCBI
Cytogenetic Map14q21NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buta-1,3-diene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chlordecone  (ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dichloroacetic acid  (ISO)
diethyl malate  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenofibrate  (ISO)
ibuprofen  (ISO)
indometacin  (ISO)
inulin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
morphine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
obeticholic acid  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (EXP)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (EXP,ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Gating of the cAMP signaling cascade and melatonin synthesis by the circadian clock in mammalian retina. Fukuhara C, etal., J Neurosci. 2004 Feb 25;24(8):1803-11.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Increased adenylyl cyclase type 1 mRNA, but not adenylyl cyclase type 2 in the rat hippocampus following antidepressant treatment. Jensen JB, etal., Eur Neuropsychopharmacol. 2000 Mar;10(2):105-11.
5. Differential expression of type I, II, and V adenylyl cyclase gene in the postnatal developing rat brain. Matsuoka I, etal., J Neurochem. 1997 Feb;68(2):498-506.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. A nuclear location for Ca2+-activated adenylyl cyclases I and III in neurones. Parkinson NA and Bolsover SR, Brain Res Mol Brain Res. 2001 Jul 13;91(1-2):43-9.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Comprehensive gene review and curation RGD comprehensive gene curation
15. Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies. Sadana R and Dessauer CW, Neurosignals. 2009;17(1):5-22. Epub 2008 Oct 24.
16. Diurnal variation of the adenylyl cyclase type 1 in the rat pineal gland. Tzavara ET, etal., Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):11208-12.
Additional References at PubMed
PMID:9547227   PMID:10482244   PMID:11549699   PMID:12441059   PMID:14767559   PMID:16618703   PMID:17229090   PMID:17335981   PMID:18448650   PMID:19029295   PMID:19056867   PMID:22531884  
PMID:24048828   PMID:24482543   PMID:34099549  


Genomics

Comparative Map Data
Adcy1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81486,125,119 - 86,234,459 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1486,124,850 - 86,261,075 (+)EnsemblGRCr8
mRatBN7.21481,911,240 - 82,020,594 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1481,911,099 - 82,028,969 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1486,312,501 - 86,421,804 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01487,552,335 - 87,661,649 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01484,001,921 - 84,110,208 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01487,311,970 - 87,429,880 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1487,312,203 - 87,421,659 (+)Ensemblrn6Rnor6.0
Rnor_5.01480,947,153 - 81,055,801 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41487,812,256 - 87,923,402 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1480,985,818 - 81,095,021 (+)NCBICelera
RGSC_v3.11487,831,237 - 87,942,547 (+)NCBI
Cytogenetic Map14q21NCBI
ADCY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38745,574,140 - 45,723,116 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl745,574,140 - 45,723,116 (+)Ensemblhg38GRCh38
GRCh37745,613,739 - 45,762,715 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36745,580,646 - 45,729,237 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34745,387,360 - 45,535,952NCBI
Celera745,713,145 - 45,861,628 (+)NCBICelera
Cytogenetic Map7p12.3NCBI
HuRef745,497,881 - 45,646,668 (+)NCBIHuRef
CHM1_1745,617,991 - 45,766,937 (+)NCBICHM1_1
T2T-CHM13v2.0745,734,849 - 45,884,850 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2745,653,346 - 45,802,046 (+)NCBI
Adcy1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39117,013,433 - 7,128,506 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl117,013,489 - 7,128,506 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38117,063,433 - 7,178,506 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl117,063,489 - 7,178,506 (+)Ensemblmm10GRCm38
MGSCv37116,963,492 - 7,078,509 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36116,963,492 - 7,078,509 (+)NCBIMGSCv36mm8
Celera117,538,560 - 7,653,962 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map114.72NCBI
Adcy1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554566,841,637 - 6,930,990 (-)Ensembl
ChiLan1.0NW_0049554566,833,992 - 6,930,990 (-)NCBIChiLan1.0ChiLan1.0
ADCY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2650,488,461 - 50,636,235 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1798,813,198 - 98,963,382 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0746,289,042 - 46,436,839 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1746,354,645 - 46,501,637 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl746,354,640 - 46,492,549 (+)EnsemblpanPan2panpan1.1
ADCY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1161,064,644 - 1,166,864 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl161,037,162 - 1,167,094 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha16484,554 - 595,249 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
Dog10K_Boxer_Tasha161,840,487 - 1,857,161 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0161,051,164 - 1,153,484 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl161,023,782 - 1,153,699 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1161,041,775 - 1,139,427 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.016977,374 - 1,056,190 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01696,213 - 197,299 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adcy1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118101,098,778 - 101,252,942 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647820,310,503 - 20,456,141 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647820,310,509 - 20,477,506 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADCY1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1850,051,364 - 50,143,628 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11850,043,572 - 50,143,549 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21854,887,477 - 54,978,872 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADCY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12112,976,687 - 13,117,876 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2112,979,033 - 13,117,730 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660629,421,819 - 9,563,930 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adcy1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247406,922,879 - 7,003,658 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247406,915,445 - 7,003,299 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Adcy1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11175,972,922 - 76,078,765 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Adcy1
815 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:88
Interacting mature miRNAs:94
Transcripts:ENSRNOT00000011043
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
70153Bp59Blood pressure QTL 593.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)147297021087582095Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat

Markers in Region
RH143186  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21481,918,467 - 81,918,698 (+)MAPPERmRatBN7.2
Rnor_6.01487,319,457 - 87,319,687NCBIRnor6.0
Rnor_5.01480,954,380 - 80,954,610UniSTSRnor5.0
RGSC_v3.41487,819,481 - 87,819,711UniSTSRGSC3.4
Celera1480,993,033 - 80,993,263UniSTS
Cytogenetic Map14q21UniSTS
RH138569  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21481,918,560 - 81,918,698 (+)MAPPERmRatBN7.2
Rnor_6.01487,319,550 - 87,319,687NCBIRnor6.0
Rnor_5.01480,954,473 - 80,954,610UniSTSRnor5.0
RGSC_v3.41487,819,574 - 87,819,711UniSTSRGSC3.4
Celera1480,993,126 - 80,993,263UniSTS
RH 3.4 Map14575.2UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 11 66 147 91 90 59 62 59 6 320 160 9 126 77 91 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000088032   ⟹   ENSRNOP00000070999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1486,124,904 - 86,261,075 (+)Ensembl
mRatBN7.2 Ensembl1481,911,099 - 82,028,969 (+)Ensembl
Rnor_6.0 Ensembl1487,312,203 - 87,421,659 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000162156   ⟹   ENSRNOP00000107758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1486,124,850 - 86,235,460 (+)Ensembl
RefSeq Acc Id: NM_001107239   ⟹   NP_001100709
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81486,125,119 - 86,234,459 (+)NCBI
mRatBN7.21481,911,240 - 82,020,594 (+)NCBI
Rnor_6.01487,312,230 - 87,421,461 (+)NCBI
Rnor_5.01480,947,153 - 81,055,801 (+)NCBI
RGSC_v3.41487,812,256 - 87,923,402 (+)RGD
Celera1480,985,818 - 81,095,021 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100709 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL76022 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070999.3
  ENSRNOP00000107758
  ENSRNOP00000107758.1
RefSeq Acc Id: NP_001100709   ⟸   NM_001107239
- UniProtKB: D4A3N4 (UniProtKB/TrEMBL),   A6KJ71 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070999   ⟸   ENSRNOT00000088032
Ensembl Acc Id: ENSRNOP00000107758   ⟸   ENSRNOT00000162156
Protein Domains
Guanylate cyclase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3N4-F1-model_v2 AlphaFold D4A3N4 1-967 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309318 AgrOrtholog
BioCyc Gene G2FUF-15051 BioCyc
Ensembl Genes ENSRNOG00000059479 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000088032.3 UniProtKB/TrEMBL
  ENSRNOT00000162156 ENTREZGENE
  ENSRNOT00000162156.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.1230 UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/TrEMBL
  AC_N UniProtKB/TrEMBL
  Adcy UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/TrEMBL
KEGG Report rno:305509 UniProtKB/TrEMBL
NCBI Gene 305509 ENTREZGENE
PANTHER ADENYLATE CYCLASE TYPE 1 UniProtKB/TrEMBL
  ADENYLATE CYCLASE TYPE 1 UniProtKB/TrEMBL
Pfam AC_N UniProtKB/TrEMBL
  Guanylate_cyc UniProtKB/TrEMBL
PhenoGen Adcy1 PhenoGen
PIRSF Ade_cyc UniProtKB/TrEMBL
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000059479 RatGTEx
SMART CYCc UniProtKB/TrEMBL
Superfamily-SCOP A/G_cyclase UniProtKB/TrEMBL
UniProt A0ABK0LB28_RAT UniProtKB/TrEMBL
  A6KJ71 ENTREZGENE, UniProtKB/TrEMBL
  D4A3N4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-29 Adcy1  adenylate cyclase 1  Adcy1  adenylate cyclase 1 (brain)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Adcy1  adenylate cyclase 1 (brain)  Adcy1  adenylate cyclase 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Adcy1  adenylate cyclase 1   Adcy1_predicted  adenylate cyclase 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Adcy1_predicted  adenylate cyclase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED