Frmd4a (FERM domain containing 4A) - Rat Genome Database

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Gene: Frmd4a (FERM domain containing 4A) Rattus norvegicus
Analyze
Symbol: Frmd4a
Name: FERM domain containing 4A
RGD ID: 1309050
Description: Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in negative regulation of protein secretion and positive regulation of protein secretion. Predicted to act upstream of or within establishment of epithelial cell polarity. Predicted to be located in cytoplasm. Predicted to be active in adherens junction and bicellular tight junction. Orthologous to human FRMD4A (FERM domain containing 4A); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FERM domain-containing protein 4A; LOC307128; RGD1309050; similar to mKIAA1294 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,577,062 - 79,167,924 (-)NCBIGRCr8
mRatBN7.21773,667,787 - 74,258,487 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,667,789 - 74,258,687 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1777,163,911 - 77,439,358 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,999,819 - 81,275,052 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01775,047,372 - 75,322,802 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,642,302 - 77,918,210 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01779,297,096 - 79,568,891 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,783,244 - 85,068,101 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,797,230 - 84,969,852 (-)NCBI
Celera1773,107,924 - 73,382,408 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
apigenin  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
crotonaldehyde  (ISO)
Cuprizon  (EXP)
dexamethasone  (ISO)
dibutyl phthalate  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
melphalan  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
pentanal  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:20080746   PMID:27044754  


Genomics

Comparative Map Data
Frmd4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81778,577,062 - 79,167,924 (-)NCBIGRCr8
mRatBN7.21773,667,787 - 74,258,487 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1773,667,789 - 74,258,687 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1777,163,911 - 77,439,358 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01780,999,819 - 81,275,052 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01775,047,372 - 75,322,802 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01777,642,302 - 77,918,210 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01779,297,096 - 79,568,891 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41784,783,244 - 85,068,101 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11784,797,230 - 84,969,852 (-)NCBI
Celera1773,107,924 - 73,382,408 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
FRMD4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381013,643,706 - 14,330,924 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1013,643,706 - 14,462,142 (-)EnsemblGRCh38hg38GRCh38
GRCh371013,685,706 - 14,372,923 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361013,725,712 - 14,412,872 (-)NCBINCBI36Build 36hg18NCBI36
Build 341013,725,717 - 14,412,889NCBI
Celera1013,612,839 - 14,300,505 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1013,597,345 - 14,283,686 (-)NCBIHuRef
CHM1_11013,686,509 - 14,373,491 (-)NCBICHM1_1
T2T-CHM13v2.01013,656,726 - 14,343,958 (-)NCBIT2T-CHM13v2.0
Frmd4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3924,022,461 - 4,618,854 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl24,022,528 - 4,618,854 (+)EnsemblGRCm39 Ensembl
GRCm3824,017,650 - 4,614,043 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl24,017,717 - 4,614,043 (+)EnsemblGRCm38mm10GRCm38
MGSCv3724,073,909 - 4,535,089 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3624,070,144 - 4,531,214 (+)NCBIMGSCv36mm8
Celera24,101,182 - 4,566,365 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map22.31NCBI
Frmd4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542919,981,599 - 20,552,700 (+)NCBIChiLan1.0ChiLan1.0
FRMD4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2826,165,087 - 26,853,369 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11026,170,434 - 26,858,699 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01013,643,371 - 14,331,368 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11013,975,765 - 14,301,636 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1013,975,845 - 14,192,399 (-)Ensemblpanpan1.1panPan2
FRMD4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1222,128,030 - 22,857,707 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl222,248,890 - 22,857,220 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha219,259,234 - 19,918,176 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0222,429,591 - 23,165,387 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl222,550,847 - 23,162,904 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,629,464 - 20,364,943 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0220,464,330 - 21,199,689 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0221,091,650 - 21,827,732 (+)NCBIUU_Cfam_GSD_1.0
Frmd4a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093445,864,218 - 6,292,539 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936613414,473 - 842,905 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936613414,881 - 710,210 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRMD4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1047,384,861 - 48,049,706 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11047,384,867 - 48,048,948 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21052,505,704 - 52,750,445 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FRMD4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1913,667,535 - 14,361,311 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl913,675,726 - 13,916,694 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605119,205,751 - 19,899,254 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Frmd4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248051,073,132 - 1,590,661 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248051,072,327 - 1,593,563 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Frmd4a
5045 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:69
Count of miRNA genes:62
Interacting mature miRNAs:65
Transcripts:ENSRNOT00000045765
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358295Aocep1Aortic cell protein QTL 16.17e-07thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172393042179524188Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)176570358081153923Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172418489079524188Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)177177462182479847Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176364000973951021Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)175900564977910000Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)177100332581153923Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172393042179524188Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2393042179524188Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172393042179524188Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)175724684382046127Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat

Markers in Region
RH133022  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,890,252 - 73,890,456 (+)MAPPERmRatBN7.2
Rnor_6.01777,858,158 - 77,858,361NCBIRnor6.0
Rnor_5.01779,512,562 - 79,512,765UniSTSRnor5.0
RGSC_v3.41785,011,247 - 85,011,450UniSTSRGSC3.4
Celera1773,326,199 - 73,326,402UniSTS
Cytogenetic Map17q12.3UniSTS
BI278113  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,682,947 - 73,683,124 (+)MAPPERmRatBN7.2
Rnor_6.01777,654,244 - 77,654,420NCBIRnor6.0
Rnor_5.01779,309,038 - 79,309,214UniSTSRnor5.0
RGSC_v3.41784,795,186 - 84,795,362UniSTSRGSC3.4
Celera1773,119,866 - 73,120,042UniSTS
RH 3.4 Map17732.1UniSTS
Cytogenetic Map17q12.3UniSTS
BF400208  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01777,656,384 - 77,656,560NCBIRnor6.0
Rnor_5.01779,311,178 - 79,311,354UniSTSRnor5.0
RGSC_v3.41784,797,837 - 84,798,033UniSTSRGSC3.4
RGSC_v3.41784,797,326 - 84,798,033UniSTSRGSC3.4
Celera1773,122,002 - 73,122,198UniSTS
RH 3.4 Map17732.9UniSTS
Cytogenetic Map17q12.3UniSTS
RH140014  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,717,574 - 73,717,771 (+)MAPPERmRatBN7.2
Rnor_6.01777,688,502 - 77,688,698NCBIRnor6.0
Rnor_5.01779,343,296 - 79,343,492UniSTSRnor5.0
Celera1773,153,855 - 73,154,051UniSTS
RH 3.4 Map17732.6UniSTS
Cytogenetic Map17q12.3UniSTS
BF390950  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21773,685,010 - 73,685,164 (+)MAPPERmRatBN7.2
Rnor_6.01777,656,306 - 77,656,459NCBIRnor6.0
Rnor_5.01779,311,100 - 79,311,253UniSTSRnor5.0
RGSC_v3.41784,797,759 - 84,797,912UniSTSRGSC3.4
RGSC_v3.41784,797,248 - 84,797,401UniSTSRGSC3.4
Celera1773,121,924 - 73,122,077UniSTS
RH 3.4 Map17731.5UniSTS
Cytogenetic Map17q12.3UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000045765   ⟹   ENSRNOP00000044582
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1773,667,789 - 73,722,241 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000081645   ⟹   ENSRNOP00000072339
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1773,670,527 - 74,258,687 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095260   ⟹   ENSRNOP00000097387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1773,667,789 - 73,875,505 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096103   ⟹   ENSRNOP00000095782
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1773,667,789 - 74,002,584 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104402   ⟹   ENSRNOP00000096584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1773,667,789 - 73,946,644 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105615   ⟹   ENSRNOP00000095559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1773,667,789 - 73,975,025 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113916   ⟹   ENSRNOP00000084435
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1773,667,789 - 74,112,817 (-)Ensembl
RefSeq Acc Id: NM_001191821   ⟹   NP_001178750
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,580,278 - 78,855,876 (-)NCBI
mRatBN7.21773,671,006 - 73,946,644 (-)NCBI
Rnor_6.01777,642,302 - 77,918,210 (-)NCBI
Rnor_5.01779,297,096 - 79,568,891 (-)NCBI
Celera1773,107,924 - 73,382,408 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095783   ⟹   XP_038951711
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,580,313 - 78,858,887 (-)NCBI
mRatBN7.21773,667,787 - 73,948,038 (-)NCBI
RefSeq Acc Id: XM_039095784   ⟹   XP_038951712
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 78,884,548 (-)NCBI
mRatBN7.21773,667,787 - 73,975,349 (-)NCBI
RefSeq Acc Id: XM_039095786   ⟹   XP_038951714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 78,899,559 (-)NCBI
mRatBN7.21773,667,787 - 73,990,411 (-)NCBI
RefSeq Acc Id: XM_039095787   ⟹   XP_038951715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,580,313 - 78,884,554 (-)NCBI
mRatBN7.21773,667,787 - 73,975,353 (-)NCBI
RefSeq Acc Id: XM_039095788   ⟹   XP_038951716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 79,167,924 (-)NCBI
mRatBN7.21773,667,787 - 74,258,487 (-)NCBI
RefSeq Acc Id: XM_039095789   ⟹   XP_038951717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 78,785,358 (-)NCBI
mRatBN7.21773,667,787 - 73,876,119 (-)NCBI
RefSeq Acc Id: XM_039095790   ⟹   XP_038951718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 78,784,691 (-)NCBI
mRatBN7.21773,667,787 - 73,873,771 (-)NCBI
RefSeq Acc Id: XM_039095791   ⟹   XP_038951719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 78,785,495 (-)NCBI
mRatBN7.21773,667,787 - 73,876,249 (-)NCBI
RefSeq Acc Id: XM_039095793   ⟹   XP_038951721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 78,629,826 (-)NCBI
mRatBN7.21773,667,787 - 73,720,680 (-)NCBI
RefSeq Acc Id: XM_039095794   ⟹   XP_038951722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 78,630,066 (-)NCBI
mRatBN7.21773,667,787 - 73,721,475 (-)NCBI
RefSeq Acc Id: XM_039095796   ⟹   XP_038951724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 78,612,652 (-)NCBI
mRatBN7.21773,667,787 - 73,703,387 (-)NCBI
RefSeq Acc Id: XM_063276496   ⟹   XP_063132566
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81778,577,062 - 79,020,402 (-)NCBI
RefSeq Acc Id: NP_001178750   ⟸   NM_001191821
- UniProtKB: A0A8I6AR03 (UniProtKB/TrEMBL),   A0A0G2K2R0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038951716   ⟸   XM_039095788
- Peptide Label: isoform X5
- UniProtKB: A0A0G2K2R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951714   ⟸   XM_039095786
- Peptide Label: isoform X3
- UniProtKB: A0A8I6B3B1 (UniProtKB/TrEMBL),   A0A0G2K2R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951715   ⟸   XM_039095787
- Peptide Label: isoform X4
- UniProtKB: A0A0G2K2R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951712   ⟸   XM_039095784
- Peptide Label: isoform X2
- UniProtKB: A0A8I6APE6 (UniProtKB/TrEMBL),   A0A0G2K2R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951711   ⟸   XM_039095783
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951719   ⟸   XM_039095791
- Peptide Label: isoform X7
- UniProtKB: A0A0G2K2R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951717   ⟸   XM_039095789
- Peptide Label: isoform X7
- UniProtKB: A0A0G2K2R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951718   ⟸   XM_039095790
- Peptide Label: isoform X7
- UniProtKB: A0A0G2K2R0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951722   ⟸   XM_039095794
- Peptide Label: isoform X8
- UniProtKB: A0A8I6GMH6 (UniProtKB/TrEMBL),   D3ZU85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951721   ⟸   XM_039095793
- Peptide Label: isoform X8
- UniProtKB: A0A8I6GMH6 (UniProtKB/TrEMBL),   D3ZU85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038951724   ⟸   XM_039095796
- Peptide Label: isoform X9
- UniProtKB: D3ZU85 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000096584   ⟸   ENSRNOT00000104402
Ensembl Acc Id: ENSRNOP00000072339   ⟸   ENSRNOT00000081645
Ensembl Acc Id: ENSRNOP00000097387   ⟸   ENSRNOT00000095260
Ensembl Acc Id: ENSRNOP00000084435   ⟸   ENSRNOT00000113916
Ensembl Acc Id: ENSRNOP00000095559   ⟸   ENSRNOT00000105615
Ensembl Acc Id: ENSRNOP00000095782   ⟸   ENSRNOT00000096103
Ensembl Acc Id: ENSRNOP00000044582   ⟸   ENSRNOT00000045765
RefSeq Acc Id: XP_063132566   ⟸   XM_063276496
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZZA8 (UniProtKB/TrEMBL),   A0A0G2K2R0 (UniProtKB/TrEMBL)
Protein Domains
Cytohesin Ubiquitin Protein Inducing   FERM   FERM C-terminal PH-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZU85-F1-model_v2 AlphaFold D3ZU85 1-794 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309050 AgrOrtholog
BioCyc Gene G2FUF-8677 BioCyc
Ensembl Genes ENSRNOG00000018500 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045765.6 UniProtKB/TrEMBL
  ENSRNOT00000081645.2 UniProtKB/TrEMBL
  ENSRNOT00000095260.1 UniProtKB/TrEMBL
  ENSRNOT00000096103.1 UniProtKB/TrEMBL
  ENSRNOT00000104402.1 UniProtKB/TrEMBL
  ENSRNOT00000105615.1 UniProtKB/TrEMBL
  ENSRNOT00000113916.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
InterPro Band_41_domain UniProtKB/TrEMBL
  DUF3338 UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_central UniProtKB/TrEMBL
  FERM_CS UniProtKB/TrEMBL
  FERM_domain UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
  FERM_PH-like_C UniProtKB/TrEMBL
  FRMD4A/B UniProtKB/TrEMBL
  FRMD4A/B_FERM_C UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report rno:307128 UniProtKB/TrEMBL
NCBI Gene 307128 ENTREZGENE
PANTHER FERM DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  FERM DOMAIN-CONTAINING PROTEIN 4A UniProtKB/TrEMBL
Pfam CUPID UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
  FERM_M UniProtKB/TrEMBL
  FERM_N UniProtKB/TrEMBL
PhenoGen Frmd4a PhenoGen
PRINTS BAND41 UniProtKB/TrEMBL
PROSITE FERM_1 UniProtKB/TrEMBL
  FERM_2 UniProtKB/TrEMBL
  FERM_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018500 RatGTEx
SMART B41 UniProtKB/TrEMBL
  FERM_C UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47031 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A0G2K2R0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZZA8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6APE6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AR03 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6B3B1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GMH6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZU85 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Frmd4a  FERM domain containing 4A   Frmd4a_predicted  FERM domain containing 4A (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Frmd4a_predicted  FERM domain containing 4A (predicted)  RGD1309050_predicted  similar to mKIAA1294 protein (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1309050_predicted  similar to mKIAA1294 protein (predicted)  LOC307128_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC307128_predicted  similar to mKIAA1294 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL