Adhfe1 (alcohol dehydrogenase, iron containing, 1) - Rat Genome Database

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Gene: Adhfe1 (alcohol dehydrogenase, iron containing, 1) Rattus norvegicus
Analyze
Symbol: Adhfe1
Name: alcohol dehydrogenase, iron containing, 1
RGD ID: 1308863
Description: Predicted to enable alcohol dehydrogenase (NAD+) activity and hydroxyacid-oxoacid transhydrogenase activity. Predicted to be involved in L-glutamate catabolic process via 2-hydroxyglutarate. Predicted to be active in mitochondrion. Orthologous to human ADHFE1 (alcohol dehydrogenase iron containing 1); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: alcohol dehydrogenase iron-containing protein 1; HOT; hydroxyacid-oxoacid transhydrogenase, mitochondrial; LOC362474
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8514,488,784 - 14,515,405 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl514,488,788 - 14,515,835 (-)EnsemblGRCr8
mRatBN7.259,705,966 - 9,732,580 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl59,705,970 - 9,732,517 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx511,859,881 - 11,886,366 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0513,491,307 - 13,517,863 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0513,194,558 - 13,221,043 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.059,403,194 - 9,429,783 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl59,403,196 - 9,429,859 (-)Ensemblrn6Rnor6.0
Rnor_5.0514,202,072 - 14,228,623 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.459,276,929 - 9,303,483 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera59,215,174 - 9,241,478 (-)NCBICelera
RGSC_v3.159,276,932 - 9,303,483 (-)NCBI
Cytogenetic Map5q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
amitrole  (EXP)
Benoxacor  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
choline  (ISO)
cisplatin  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glucose  (ISO)
GSK-J4  (ISO)
GW 4064  (ISO)
indometacin  (ISO)
inulin  (ISO)
L-methionine  (ISO)
Mesaconitine  (EXP)
methapyrilene  (EXP)
methotrexate  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylephrine  (EXP)
phlorizin  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
Propiverine  (EXP)
rotenone  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sulindac  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP)
triadimefon  (EXP)
trichloroethene  (EXP)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
mitochondrion  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:16435184   PMID:17559793  


Genomics

Comparative Map Data
Adhfe1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8514,488,784 - 14,515,405 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl514,488,788 - 14,515,835 (-)EnsemblGRCr8
mRatBN7.259,705,966 - 9,732,580 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl59,705,970 - 9,732,517 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx511,859,881 - 11,886,366 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0513,491,307 - 13,517,863 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0513,194,558 - 13,221,043 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.059,403,194 - 9,429,783 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl59,403,196 - 9,429,859 (-)Ensemblrn6Rnor6.0
Rnor_5.0514,202,072 - 14,228,623 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.459,276,929 - 9,303,483 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera59,215,174 - 9,241,478 (-)NCBICelera
RGSC_v3.159,276,932 - 9,303,483 (-)NCBI
Cytogenetic Map5q11NCBI
ADHFE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38866,432,504 - 66,468,907 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl866,432,467 - 66,468,907 (+)Ensemblhg38GRCh38
GRCh37867,344,739 - 67,381,142 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36867,507,272 - 67,543,598 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34867,507,287 - 67,543,596NCBI
Celera863,336,419 - 63,372,728 (+)NCBICelera
Cytogenetic Map8q13.1NCBI
HuRef862,834,707 - 62,871,046 (+)NCBIHuRef
CHM1_1867,399,402 - 67,435,714 (+)NCBICHM1_1
T2T-CHM13v2.0866,858,074 - 66,894,463 (+)NCBIT2T-CHM13v2.0
Adhfe1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3919,618,173 - 9,648,195 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl19,618,173 - 9,650,898 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3819,547,948 - 9,577,970 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl19,547,948 - 9,580,673 (+)Ensemblmm10GRCm38
MGSCv3719,538,127 - 9,568,049 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3619,533,294 - 9,563,182 (+)NCBIMGSCv36mm8
Celera19,522,208 - 9,552,158 (+)NCBICelera
Cytogenetic Map1A2NCBI
cM Map12.08NCBI
Adhfe1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544412,706,912 - 12,745,056 (-)Ensembl
ChiLan1.0NW_00495544412,706,404 - 12,745,106 (-)NCBIChiLan1.0ChiLan1.0
ADHFE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2782,170,179 - 82,206,474 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1857,809,545 - 57,847,393 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0862,975,711 - 63,012,102 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1864,642,062 - 64,678,312 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl864,642,062 - 64,678,306 (+)EnsemblpanPan2panpan1.1
ADHFE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12916,019,183 - 16,054,060 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2916,019,246 - 16,050,535 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2916,333,976 - 16,376,910 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02916,097,874 - 16,141,174 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2916,097,773 - 16,182,387 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12916,130,334 - 16,173,264 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02916,229,683 - 16,272,642 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02916,485,707 - 16,528,705 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Adhfe1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530367,228,274 - 67,256,260 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364967,530,415 - 7,562,847 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364967,529,217 - 7,562,881 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADHFE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl468,250,646 - 68,285,405 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1468,251,970 - 68,285,436 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2474,419,430 - 74,452,888 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADHFE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1862,300,884 - 62,337,886 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl862,300,979 - 62,338,096 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603979,168,492 - 79,205,076 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adhfe1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474424,880,010 - 24,913,873 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474424,883,104 - 24,913,885 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Adhfe1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11144,293,382 - 144,319,687 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Adhfe1
341 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:220
Count of miRNA genes:157
Interacting mature miRNAs:175
Transcripts:ENSRNOT00000009462
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293666Bmd38Bone mineral density QTL 384.4femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)51373115343590997Rat
2312562Pur18Proteinuria QTL 182.60.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)5692228237468560Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
1300117Hrtrt8Heart rate QTL 83.49heart pumping trait (VT:2000009)heart rate (CMO:0000002)5862723052665523Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
631827Alc4Alcohol consumption QTL 43.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)51297048025683802Rat
2313085Bss59Bone structure and strength QTL 592.90.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)5862723053627230Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat

Markers in Region
RH140347  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.259,728,288 - 9,728,424 (+)MAPPERmRatBN7.2
Rnor_6.059,425,514 - 9,425,649NCBIRnor6.0
Rnor_5.0514,224,392 - 14,224,527UniSTSRnor5.0
RGSC_v3.459,299,252 - 9,299,387UniSTSRGSC3.4
Celera59,237,247 - 9,237,382UniSTS
RH 3.4 Map551.6UniSTS
Cytogenetic Map5q11UniSTS
RH127402  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.259,706,073 - 9,706,280 (+)MAPPERmRatBN7.2
Rnor_6.059,403,302 - 9,403,508NCBIRnor6.0
Rnor_5.0514,202,180 - 14,202,386UniSTSRnor5.0
RGSC_v3.459,277,037 - 9,277,243UniSTSRGSC3.4
Celera59,215,282 - 9,215,488UniSTS
Cytogenetic Map5q11UniSTS
RH143168  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.259,715,682 - 9,715,884 (+)MAPPERmRatBN7.2
Rnor_6.059,412,910 - 9,413,111NCBIRnor6.0
Rnor_5.0514,211,788 - 14,211,989UniSTSRnor5.0
RGSC_v3.459,286,646 - 9,286,847UniSTSRGSC3.4
Celera59,224,637 - 9,224,838UniSTS
RH 3.4 Map552.1UniSTS
Cytogenetic Map5q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 66 59 6 330 166 11 138 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000009462   ⟹   ENSRNOP00000009462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl514,488,788 - 14,511,297 (-)Ensembl
mRatBN7.2 Ensembl59,705,970 - 9,732,517 (-)Ensembl
Rnor_6.0 Ensembl59,403,196 - 9,429,859 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000123710   ⟹   ENSRNOP00000106825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl514,488,788 - 14,515,835 (-)Ensembl
RefSeq Acc Id: NM_001025423   ⟹   NP_001020594
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,488,784 - 14,515,338 (-)NCBI
mRatBN7.259,705,966 - 9,732,521 (-)NCBI
Rnor_6.059,403,194 - 9,429,745 (-)NCBI
Rnor_5.0514,202,072 - 14,228,623 (-)NCBI
RGSC_v3.459,276,929 - 9,303,483 (-)RGD
Celera59,215,174 - 9,241,478 (-)RGD
Sequence:
RefSeq Acc Id: XM_039110202   ⟹   XP_038966130
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,488,784 - 14,513,163 (-)NCBI
mRatBN7.259,705,966 - 9,729,475 (-)NCBI
RefSeq Acc Id: XM_039110203   ⟹   XP_038966131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,488,784 - 14,515,338 (-)NCBI
mRatBN7.259,705,966 - 9,732,525 (-)NCBI
RefSeq Acc Id: XM_039110205   ⟹   XP_038966133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,488,784 - 14,513,175 (-)NCBI
mRatBN7.259,705,966 - 9,729,499 (-)NCBI
RefSeq Acc Id: XM_039110206   ⟹   XP_038966134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,488,784 - 14,515,405 (-)NCBI
mRatBN7.259,705,966 - 9,732,580 (-)NCBI
RefSeq Acc Id: XM_039110208   ⟹   XP_038966136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,488,784 - 14,515,374 (-)NCBI
mRatBN7.259,705,966 - 9,732,558 (-)NCBI
RefSeq Acc Id: XM_039110209   ⟹   XP_038966137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8514,488,784 - 14,515,211 (-)NCBI
mRatBN7.259,705,966 - 9,732,395 (-)NCBI
RefSeq Acc Id: NP_001020594   ⟸   NM_001025423
- UniProtKB: Q4QQW3 (UniProtKB/Swiss-Prot),   A6JFG4 (UniProtKB/TrEMBL),   A0A8L2Q4Z6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000009462   ⟸   ENSRNOT00000009462
RefSeq Acc Id: XP_038966134   ⟸   XM_039110206
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038966136   ⟸   XM_039110208
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038966131   ⟸   XM_039110203
- Peptide Label: isoform X1
- UniProtKB: A6JFG6 (UniProtKB/TrEMBL),   A0A8L2Q4Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038966137   ⟸   XM_039110209
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038966133   ⟸   XM_039110205
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038966130   ⟸   XM_039110202
- Peptide Label: isoform X1
- UniProtKB: A6JFG6 (UniProtKB/TrEMBL),   A0A8L2Q4Z6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000106825   ⟸   ENSRNOT00000123710
Protein Domains
Alcohol dehydrogenase iron-type/glycerol   Fe-containing alcohol dehydrogenase-like C-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4QQW3-F1-model_v2 AlphaFold Q4QQW3 1-467 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693537
Promoter ID:EPDNEW_R4062
Type:initiation region
Name:Adhfe1_1
Description:alcohol dehydrogenase, iron containing, 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.059,429,757 - 9,429,817EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308863 AgrOrtholog
BioCyc Gene G2FUF-42195 BioCyc
Ensembl Genes ENSRNOG00000007069 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000009462 ENTREZGENE
  ENSRNOT00000123710 ENTREZGENE
Gene3D-CATH 3.40.50.1970 UniProtKB/Swiss-Prot
  Dehydroquinate synthase-like - alpha domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7126623 IMAGE-MGC_LOAD
  IMAGE:7323001 IMAGE-MGC_LOAD
InterPro ADH_Fe/GldA UniProtKB/Swiss-Prot
  ADH_Fe_C UniProtKB/Swiss-Prot
  Alcohol_dehydrogenase_Fe UniProtKB/Swiss-Prot
  HOT UniProtKB/Swiss-Prot
KEGG Report rno:362474 UniProtKB/Swiss-Prot
MGC_CLONE MGC:116068 IMAGE-MGC_LOAD
  MGC:94121 IMAGE-MGC_LOAD
NCBI Gene 362474 ENTREZGENE
PANTHER HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL UniProtKB/Swiss-Prot
  PTHR11496 UniProtKB/Swiss-Prot
Pfam ADH_Fe_C UniProtKB/Swiss-Prot
  Fe-ADH UniProtKB/Swiss-Prot
PhenoGen Adhfe1 PhenoGen
RatGTEx ENSRNOG00000007069 RatGTEx
Superfamily-SCOP Dehydroquinate synthase-like UniProtKB/Swiss-Prot
UniProt A0A8L2Q4Z6 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0L970_RAT UniProtKB/TrEMBL
  A6JFG4 ENTREZGENE, UniProtKB/TrEMBL
  A6JFG6 ENTREZGENE, UniProtKB/TrEMBL
  HOT_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Adhfe1  alcohol dehydrogenase, iron containing, 1  Adhfe1_predicted  alcohol dehydrogenase, iron containing, 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Adhfe1_predicted  alcohol dehydrogenase, iron containing, 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED