Vwa8 (von Willebrand factor A domain containing 8) - Rat Genome Database

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Gene: Vwa8 (von Willebrand factor A domain containing 8) Rattus norvegicus
Analyze
Symbol: Vwa8
Name: von Willebrand factor A domain containing 8
RGD ID: 1308772
Description: Predicted to enable ATP hydrolysis activity. Predicted to be located in mitochondrion and peroxisome. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in retinitis pigmentosa 97. Orthologous to human VWA8 (von Willebrand factor A domain containing 8); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC290381; RGD1308772; similar to KIAA0564 protein; von Willebrand factor A domain-containing protein 8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81560,661,764 - 60,985,971 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1560,661,877 - 60,985,971 (+)EnsemblGRCr8
mRatBN7.21554,252,703 - 54,576,871 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1554,252,584 - 54,576,870 (+)EnsemblmRatBN7.2
Rnor_6.01561,069,439 - 61,153,292 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01561,158,510 - 61,467,462 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1561,069,581 - 61,152,506 (+)Ensemblrn6Rnor6.0
Rnor_5.01564,733,018 - 64,817,848 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01565,106,678 - 65,131,504 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41559,993,882 - 60,364,838 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1553,842,678 - 54,161,011 (+)NCBICelera
RGSC_v3.11559,950,242 - 60,379,537 (+)NCBI
Cytogenetic Map15q11-q12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
mitochondrion  (IEA,ISO)
peroxisome  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14651853   PMID:28414126   PMID:30204880   PMID:31630795  


Genomics

Comparative Map Data
Vwa8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81560,661,764 - 60,985,971 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1560,661,877 - 60,985,971 (+)EnsemblGRCr8
mRatBN7.21554,252,703 - 54,576,871 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1554,252,584 - 54,576,870 (+)EnsemblmRatBN7.2
Rnor_6.01561,069,439 - 61,153,292 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01561,158,510 - 61,467,462 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1561,069,581 - 61,152,506 (+)Ensemblrn6Rnor6.0
Rnor_5.01564,733,018 - 64,817,848 (+)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.01565,106,678 - 65,131,504 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41559,993,882 - 60,364,838 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1553,842,678 - 54,161,011 (+)NCBICelera
RGSC_v3.11559,950,242 - 60,379,537 (+)NCBI
Cytogenetic Map15q11-q12NCBI
VWA8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381341,566,835 - 41,961,109 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1341,566,835 - 41,961,120 (-)Ensemblhg38GRCh38
GRCh371342,140,971 - 42,535,245 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361341,038,961 - 41,433,221 (-)NCBIBuild 36Build 36hg18NCBI36
Celera1323,199,011 - 23,592,898 (-)NCBICelera
Cytogenetic Map13q14.11NCBI
HuRef1322,941,888 - 23,338,138 (-)NCBIHuRef
CHM1_11342,108,485 - 42,502,867 (-)NCBICHM1_1
T2T-CHM13v2.01340,785,956 - 41,180,365 (-)NCBIT2T-CHM13v2.0
Vwa8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391479,086,489 - 79,439,750 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1479,086,492 - 79,439,750 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381478,849,058 - 79,202,310 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1478,849,052 - 79,202,310 (+)Ensemblmm10GRCm38
MGSCv371479,248,985 - 79,602,117 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361477,503,772 - 77,936,465 (+)NCBIMGSCv36mm8
Celera1476,362,512 - 76,701,437 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1441.9NCBI
Vwa8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555184,351,781 - 4,723,479 (+)Ensembl
ChiLan1.0NW_0049555184,351,781 - 4,723,479 (+)NCBIChiLan1.0ChiLan1.0
VWA8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21441,065,135 - 41,458,200 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11332,168,718 - 32,561,732 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01322,750,083 - 23,142,860 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11341,339,379 - 41,729,689 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1341,339,379 - 41,729,661 (-)EnsemblpanPan2panpan1.1
VWA8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1228,799,044 - 9,153,627 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl228,798,090 - 9,149,296 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha228,793,300 - 9,146,711 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0229,025,235 - 9,379,824 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl229,039,291 - 9,376,614 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1228,717,913 - 9,072,245 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0228,768,009 - 9,122,199 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0228,780,057 - 9,133,927 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC101965792
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945151,964,945 - 152,276,047 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367471,797,136 - 2,064,072 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367471,798,200 - 2,018,722 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VWA8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1125,064,771 - 25,457,134 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11125,064,780 - 25,455,287 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21125,821,408 - 26,011,445 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VWA8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1319,767,190 - 20,148,027 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl319,866,921 - 20,147,976 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605724,064,072 - 24,448,338 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vwa8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474813,159,518 - 13,631,333 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474813,159,660 - 13,630,727 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Vwa8
1996 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:117
Interacting mature miRNAs:133
Transcripts:ENSRNOT00000013780, ENSRNOT00000070840, ENSRNOT00000074956
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155079449473699215Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2317050Aia24Adjuvant induced arthritis QTL 242.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)155284790873690657Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
1576315Schws6Schwannoma susceptibility QTL 60.0069nervous system integrity trait (VT:0010566)post-insult time of death (CMO:0002005)155380615298806152Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

Markers in Region
D15Got65  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,422,038 - 54,422,145 (+)MAPPERmRatBN7.2
Rnor_6.01561,307,664 - 61,307,770NCBIRnor6.0
Rnor_5.01564,972,305 - 64,972,411UniSTSRnor5.0
RGSC_v3.41560,163,434 - 60,163,540RGDRGSC3.4
RGSC_v3.41560,163,435 - 60,163,541UniSTSRGSC3.4
Celera1554,011,730 - 54,011,836UniSTS
RGSC_v3.11560,179,214 - 60,179,320RGD
RH 3.4 Map15452.3RGD
RH 3.4 Map15452.3UniSTS
Cytogenetic Map15q11-q12UniSTS
RH129773  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,453,388 - 54,453,540 (+)MAPPERmRatBN7.2
Rnor_6.01561,344,209 - 61,344,360NCBIRnor6.0
Rnor_5.01565,009,677 - 65,009,828UniSTSRnor5.0
RGSC_v3.41560,201,235 - 60,201,386UniSTSRGSC3.4
Celera1554,038,235 - 54,038,386UniSTS
RH 3.4 Map15458.0UniSTS
Cytogenetic Map15q11-q12UniSTS
RH143518  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,414,064 - 54,414,339 (+)MAPPERmRatBN7.2
Rnor_6.01561,299,691 - 61,299,965NCBIRnor6.0
Rnor_5.01564,964,332 - 64,964,606UniSTSRnor5.0
RGSC_v3.41560,155,584 - 60,155,858UniSTSRGSC3.4
Celera1554,003,757 - 54,004,031UniSTS
RH 3.4 Map15458.3UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map15q11-q12UniSTS
Cytogenetic Map15q11UniSTS
RH134704  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81560,985,648 - 60,985,920 (+)Marker Load Pipeline
mRatBN7.21554,576,552 - 54,576,824 (+)MAPPERmRatBN7.2
Rnor_6.01561,467,144 - 61,467,415NCBIRnor6.0
Rnor_5.01565,131,186 - 65,131,457UniSTSRnor5.0
RGSC_v3.41560,364,520 - 60,364,791UniSTSRGSC3.4
Celera1554,160,702 - 54,160,964UniSTS
RH 3.4 Map4685.32UniSTS
Cytogenetic Map15q11-q12UniSTS
Hars  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,415,320 - 54,415,449 (+)MAPPERmRatBN7.2
mRatBN7.21828,382,080 - 28,382,413 (+)MAPPERmRatBN7.2
Rnor_6.01829,611,977 - 29,612,309NCBIRnor6.0
Rnor_6.01561,300,947 - 61,301,075NCBIRnor6.0
Rnor_5.01829,315,784 - 29,316,116UniSTSRnor5.0
Rnor_5.01564,965,588 - 64,965,716UniSTSRnor5.0
RGSC_v3.41829,468,080 - 29,468,412UniSTSRGSC3.4
RGSC_v3.41560,156,840 - 60,156,968UniSTSRGSC3.4
Celera1554,005,013 - 54,005,141UniSTS
Celera1828,102,633 - 28,102,965UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map15q11UniSTS
Cytogenetic Map15q11-q12UniSTS
RH130568  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21828,381,729 - 28,381,937 (+)MAPPERmRatBN7.2
mRatBN7.21554,415,592 - 54,415,947 (+)MAPPERmRatBN7.2
Rnor_6.01561,301,219 - 61,301,573NCBIRnor6.0
Rnor_6.01829,611,626 - 29,611,833NCBIRnor6.0
Rnor_5.01829,315,433 - 29,315,640UniSTSRnor5.0
Rnor_5.01564,965,860 - 64,966,214UniSTSRnor5.0
RGSC_v3.41560,157,112 - 60,157,466UniSTSRGSC3.4
RGSC_v3.41829,467,729 - 29,467,936UniSTSRGSC3.4
Celera1828,102,282 - 28,102,489UniSTS
Celera1554,005,285 - 54,005,639UniSTS
RH 3.4 Map18417.7UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map15q11-q12UniSTS
Cytogenetic Map15q11UniSTS
AU048166  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,324,429 - 54,324,627 (+)MAPPERmRatBN7.2
Rnor_6.01561,207,680 - 61,207,877NCBIRnor6.0
Rnor_6.01561,141,190 - 61,141,387NCBIRnor6.0
Rnor_5.01564,806,460 - 64,806,657UniSTSRnor5.0
Rnor_5.01564,872,950 - 64,873,147UniSTSRnor5.0
RGSC_v3.41560,065,439 - 60,065,636UniSTSRGSC3.4
Celera1553,914,382 - 53,914,579UniSTS
Cytogenetic Map15q11-q12UniSTS
BF390452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,254,161 - 54,254,316 (+)MAPPERmRatBN7.2
Rnor_6.01561,070,877 - 61,071,031NCBIRnor6.0
Rnor_5.01564,736,147 - 64,736,301UniSTSRnor5.0
RGSC_v3.41559,995,178 - 59,995,332UniSTSRGSC3.4
Celera1553,844,124 - 53,844,278UniSTS
RH 3.4 Map15458.7UniSTS
Cytogenetic Map15q11-q12UniSTS
AW535983  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,314,352 - 54,314,502 (+)MAPPERmRatBN7.2
Rnor_6.01561,197,603 - 61,197,752NCBIRnor6.0
Rnor_6.01561,131,113 - 61,131,262NCBIRnor6.0
Rnor_5.01564,862,873 - 64,863,022UniSTSRnor5.0
Rnor_5.01564,796,383 - 64,796,532UniSTSRnor5.0
RGSC_v3.41560,055,362 - 60,055,511UniSTSRGSC3.4
Celera1553,904,305 - 53,904,454UniSTS
RH 3.4 Map15456.4UniSTS
Cytogenetic Map15q11-q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000084333   ⟹   ENSRNOP00000072799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1560,661,877 - 60,985,971 (+)Ensembl
mRatBN7.2 Ensembl1554,252,584 - 54,576,870 (+)Ensembl
Rnor_6.0 Ensembl1561,069,581 - 61,152,506 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000170597   ⟹   ENSRNOP00000104923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1560,661,877 - 60,985,971 (+)Ensembl
RefSeq Acc Id: NM_001427283   ⟹   NP_001414212
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,661,877 - 60,985,971 (+)NCBI
RefSeq Acc Id: XM_039094044   ⟹   XP_038949972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,681,484 - 60,985,954 (+)NCBI
mRatBN7.21554,253,008 - 54,576,871 (+)NCBI
RefSeq Acc Id: XM_039094045   ⟹   XP_038949973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,789,178 - 60,985,954 (+)NCBI
mRatBN7.21554,380,080 - 54,576,871 (+)NCBI
RefSeq Acc Id: XM_063274157   ⟹   XP_063130227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,661,764 - 60,985,954 (+)NCBI
RefSeq Acc Id: XM_063274158   ⟹   XP_063130228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,851,713 - 60,985,954 (+)NCBI
Ensembl Acc Id: ENSRNOP00000072799   ⟸   ENSRNOT00000084333
RefSeq Acc Id: XP_038949972   ⟸   XM_039094044
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949973   ⟸   XM_039094045
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063130227   ⟸   XM_063274157
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001414212   ⟸   NM_001427283
- UniProtKB: A0A0G2K3W1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130228   ⟸   XM_063274158
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000104923   ⟸   ENSRNOT00000170597
Protein Domains
VWFA

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K3W1-F1-model_v2 AlphaFold A0A0G2K3W1 1-481 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699846
Promoter ID:EPDNEW_R10367
Type:initiation region
Name:Vwa8_1
Description:von Willebrand factor A domain containing 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01561,069,486 - 61,069,546EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308772 AgrOrtholog
BioCyc Gene G2FUF-13006 BioCyc
Ensembl Genes ENSRNOG00000053145 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084333 ENTREZGENE
  ENSRNOT00000084333.2 UniProtKB/TrEMBL
  ENSRNOT00000170597 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  3.40.50.410 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ATPase_dyneun-rel_AAA UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  VWA8 UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene 290381 ENTREZGENE
PANTHER PTHR21610 UniProtKB/TrEMBL
  VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
Pfam AAA_5 UniProtKB/TrEMBL
PhenoGen Vwa8 PhenoGen
PROSITE VWFA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053145 RatGTEx
SMART AAA UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF53300 UniProtKB/TrEMBL
UniProt A0A0G2K3W1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Vwa8  von Willebrand factor A domain containing 8  RGD1308772  similar to KIAA0564 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1308772  similar to KIAA0564 protein   RGD1308772_predicted  similar to KIAA0564 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308772_predicted  similar to KIAA0564 protein (predicted)  LOC290381_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC290381_predicted  similar to KIAA0564 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL