Fbln1 (fibulin 1) - Rat Genome Database

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Gene: Fbln1 (fibulin 1) Rattus norvegicus
Analyze
Symbol: Fbln1
Name: fibulin 1
RGD ID: 1308667
Description: Predicted to enable several functions, including fibrinogen binding activity; fibronectin binding activity; and integrin binding activity. Predicted to be an extracellular matrix structural constituent. Involved in embryo implantation. Predicted to be located in basement membrane; elastic fiber; and extracellular space. Orthologous to human FBLN1 (fibulin 1); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fbln1 protein-like; fibulin-1; LOC100362423; LOC315191
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87118,190,347 - 118,269,965 (+)NCBIGRCr8
mRatBN7.27116,310,582 - 116,390,075 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7116,310,582 - 116,390,075 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7118,061,437 - 118,140,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07120,287,178 - 120,366,397 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07120,256,616 - 120,335,836 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07126,096,793 - 126,176,468 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7126,096,793 - 126,176,468 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07125,810,696 - 125,890,371 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47123,208,154 - 123,287,289 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17123,242,385 - 123,321,516 (+)NCBI
Celera7112,608,514 - 112,687,953 (+)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-phenylbutyric acid  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
amphotericin B  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
butan-1-ol  (ISO)
cadmium acetate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chlormequat chloride  (EXP)
chromium(6+)  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
Cuprizon  (EXP)
cytarabine  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (EXP,ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
folic acid  (ISO)
fulvestrant  (ISO)
furan  (EXP)
genistein  (ISO)
glycidyl methacrylate  (ISO)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
indometacin  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
medroxyprogesterone acetate  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (EXP)
mifepristone  (ISO)
monosodium L-glutamate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (EXP)
pentane-2,3-dione  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium cyanide  (ISO)
potassium dichromate  (ISO)
prednisolone  (ISO)
progesterone  (ISO)
sarin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sirolimus  (EXP)
sodium arsenite  (ISO)
sodium aurothiomalate  (ISO)
Soman  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
tetrathiomolybdate(2-)  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cycle-dependent endometrial expression and hormonal regulation of the fibulin-1 gene. Haendler B, etal., Mol Reprod Dev. 2004 Jul;68(3):279-87.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Age-related changes of cardiac gene expression following myocardial ischemia/reperfusion. Simkhovich BZ, etal., Arch Biochem Biophys. 2003 Dec 15;420(2):268-78.
Additional References at PubMed
PMID:1400330   PMID:2269669   PMID:7534784   PMID:7642629   PMID:9278415   PMID:9927660   PMID:11238726   PMID:11792823   PMID:12200142   PMID:12477932   PMID:16061471   PMID:18757743  
PMID:19609566   PMID:20551380   PMID:23376485   PMID:23533145   PMID:24006456   PMID:25661773   PMID:25834989   PMID:27068509   PMID:32640908  


Genomics

Comparative Map Data
Fbln1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87118,190,347 - 118,269,965 (+)NCBIGRCr8
mRatBN7.27116,310,582 - 116,390,075 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7116,310,582 - 116,390,075 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7118,061,437 - 118,140,654 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07120,287,178 - 120,366,397 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07120,256,616 - 120,335,836 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07126,096,793 - 126,176,468 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7126,096,793 - 126,176,468 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07125,810,696 - 125,890,371 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47123,208,154 - 123,287,289 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17123,242,385 - 123,321,516 (+)NCBI
Celera7112,608,514 - 112,687,953 (+)NCBICelera
Cytogenetic Map7q34NCBI
FBLN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382245,502,883 - 45,601,135 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2245,502,238 - 45,601,135 (+)EnsemblGRCh38hg38GRCh38
GRCh372245,898,763 - 45,997,015 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362244,277,383 - 44,375,678 (+)NCBINCBI36Build 36hg18NCBI36
Build 342244,219,255 - 44,275,128NCBI
Celera2229,809,689 - 29,909,644 (+)NCBICelera
Cytogenetic Map22q13.31NCBI
HuRef2228,859,953 - 28,942,412 (+)NCBIHuRef
CHM1_12245,857,451 - 45,955,744 (+)NCBICHM1_1
T2T-CHM13v2.02245,987,730 - 46,085,865 (+)NCBIT2T-CHM13v2.0
Fbln1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391585,090,150 - 85,170,495 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1585,090,150 - 85,170,736 (+)EnsemblGRCm39 Ensembl
GRCm381585,205,949 - 85,286,294 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1585,205,949 - 85,286,535 (+)EnsemblGRCm38mm10GRCm38
MGSCv371585,036,438 - 85,116,724 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361585,033,777 - 85,113,422 (+)NCBIMGSCv36mm8
Celera1587,331,933 - 87,412,210 (+)NCBICelera
Cytogenetic Map15E2NCBI
cM Map1540.27NCBI
Fbln1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541329,837,134 - 29,912,222 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541329,837,134 - 29,911,313 (+)NCBIChiLan1.0ChiLan1.0
FBLN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22355,327,942 - 55,426,786 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12258,026,827 - 58,125,277 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02226,390,379 - 26,488,737 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12244,583,632 - 44,666,696 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2244,582,843 - 44,666,011 (+)Ensemblpanpan1.1panPan2
FBLN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11020,498,097 - 20,564,776 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1020,498,567 - 20,627,836 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1020,418,944 - 20,535,831 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01021,232,145 - 21,315,719 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1021,232,148 - 21,315,848 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11020,951,205 - 21,068,293 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01021,264,132 - 21,382,166 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01021,444,929 - 21,562,250 (-)NCBIUU_Cfam_GSD_1.0
Fbln1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049454,170,186 - 4,231,513 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366294,170,817 - 4,242,103 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366294,170,186 - 4,242,100 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBLN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl53,839,502 - 3,927,183 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.153,839,498 - 3,927,178 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.251,071,068 - 1,158,743 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBLN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11927,962,669 - 28,061,356 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1927,962,642 - 28,061,364 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604597,273,345 - 97,370,894 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbln1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247524,109,478 - 4,190,066 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247524,109,478 - 4,189,987 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fbln1
370 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:56
Count of miRNA genes:45
Interacting mature miRNAs:52
Transcripts:ENSRNOT00000047234
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300179Kidm5Kidney mass QTL 53.51kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)743747012135012528Rat
1300112Bp183Blood pressure QTL 1833.51arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)7111182207135012528Rat
1331728Bp214Blood pressure QTL 2142.825arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)780221299124373579Rat
1331731Bp216Blood pressure QTL 2162.851arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7102297359133492884Rat
2298475Eau6Experimental allergic uveoretinitis QTL 60.0029uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)784257275129257275Rat
71114Niddm14Non-insulin dependent diabetes mellitus QTL 144.5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)784257275129257275Rat
631687Hcas1Hepatocarcinoma susceptibility QTL 13.90.001liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)791412594129807172Rat
70159Bp61Blood pressure QTL 610.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7103146217116738842Rat
1357339Stl14Serum triglyceride level QTL 143.450.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)7112729683133492707Rat
634331Pia17Pristane induced arthritis QTL 174.7joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)773829340130221005Rat
1358914Bp266Blood pressure QTL 266arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat
631504Cm27Cardiac mass QTL 273.45heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)744421311118198041Rat
634322Bw12Body weight QTL 120body mass (VT:0001259)body weight (CMO:0000012)783153392128153392Rat
70173Niddm19Non-insulin dependent diabetes mellitus QTL 194.330.00005blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)764002457135012528Rat
1549899Stresp8Stress response QTL 84.370.0008stress-related behavior trait (VT:0010451)defensive burying duration (CMO:0001961)790482196135012528Rat
2317052Aia17Adjuvant induced arthritis QTL 172.13joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)781737938126737938Rat
731176Glom5Glomerulus QTL 52.50.0035kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)796670164135012528Rat
7411607Foco15Food consumption QTL 150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2306821Bp335Blood pressure QTL 3350.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7106571501135012528Rat
631663Bw6Body weight QTL 63.4body mass (VT:0001259)body weight (CMO:0000012)7111075573134976056Rat
1558655Swd4Spike wave discharge measurement QTL 43.680.0002brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge severity grade (CMO:0001988)786983365131983365Rat
1331768Kidm10Kidney mass QTL 104.62096kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)780221299125221299Rat
61357Bp38Blood pressure QTL 381.60.052arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)741333674119109060Rat
2313102Bmd79Bone mineral density QTL 792.30.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)794811085116738842Rat
731174Uae23Urinary albumin excretion QTL 232.40.0042urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)7104603555135012528Rat
1331748Bp215Blood pressure QTL 2154.043arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)7112308254133492884Rat
7411654Foco25Food consumption QTL 259.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)775918751120918751Rat
2299163Iddm34Insulin dependent diabetes mellitus QTL 342.71blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)791281130135012528Rat
631540Bw9Body weight QTL 94.5body mass (VT:0001259)body weight (CMO:0000012)769736226117455174Rat
1358891Bp265Blood pressure QTL 2652.21arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)783591953134666232Rat

Markers in Region
AW524050  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27116,347,866 - 116,347,966 (+)MAPPERmRatBN7.2
Rnor_6.07126,134,080 - 126,134,179NCBIRnor6.0
Rnor_5.07125,847,983 - 125,848,082UniSTSRnor5.0
RGSC_v3.47123,245,143 - 123,245,242UniSTSRGSC3.4
Celera7112,645,795 - 112,645,894UniSTS
RH 3.4 Map7908.6UniSTS
Cytogenetic Map7q34UniSTS
Fbln1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27116,355,006 - 116,355,418 (+)MAPPERmRatBN7.2
Rnor_6.07126,141,220 - 126,141,631NCBIRnor6.0
Rnor_5.07125,855,123 - 125,855,534UniSTSRnor5.0
RGSC_v3.47123,252,283 - 123,252,694UniSTSRGSC3.4
Celera7112,652,935 - 112,653,346UniSTS
Cytogenetic Map7q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000047234   ⟹   ENSRNOP00000046622
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7116,310,582 - 116,390,069 (+)Ensembl
Rnor_6.0 Ensembl7126,096,793 - 126,176,468 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000088042   ⟹   ENSRNOP00000070552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7116,310,582 - 116,383,452 (+)Ensembl
Rnor_6.0 Ensembl7126,096,831 - 126,141,636 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102556   ⟹   ENSRNOP00000089007
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7116,324,600 - 116,390,075 (+)Ensembl
RefSeq Acc Id: NM_001127547   ⟹   NP_001121019
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87118,190,478 - 118,269,965 (+)NCBI
mRatBN7.27116,310,582 - 116,390,075 (+)NCBI
Rnor_6.07126,096,793 - 126,176,468 (+)NCBI
Rnor_5.07125,810,696 - 125,890,371 (+)NCBI
RGSC_v3.47123,208,154 - 123,287,289 (+)RGD
Celera7112,608,514 - 112,687,953 (+)RGD
Sequence:
RefSeq Acc Id: XM_006242161   ⟹   XP_006242223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr87118,190,347 - 118,235,324 (+)NCBI
mRatBN7.27116,310,587 - 116,355,430 (+)NCBI
Rnor_6.07126,096,813 - 126,141,643 (+)NCBI
Rnor_5.07125,810,696 - 125,890,371 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001121019 (Get FASTA)   NCBI Sequence Viewer  
  XP_006242223 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI61973 (Get FASTA)   NCBI Sequence Viewer  
  EDM15584 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000046622
  ENSRNOP00000046622.4
  ENSRNOP00000070552.2
  ENSRNOP00000089007.1
  ENSRNOP00000109223
RefSeq Acc Id: NP_001121019   ⟸   NM_001127547
- Peptide Label: precursor
- UniProtKB: A6HTD8 (UniProtKB/TrEMBL),   A0A0G2JY81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242223   ⟸   XM_006242161
- Peptide Label: isoform X1
- UniProtKB: B1WC21 (UniProtKB/TrEMBL),   D3ZQ25 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000046622   ⟸   ENSRNOT00000047234
Ensembl Acc Id: ENSRNOP00000070552   ⟸   ENSRNOT00000088042
Ensembl Acc Id: ENSRNOP00000089007   ⟸   ENSRNOT00000102556
Protein Domains
Anaphylatoxin-like   EGF-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQ25-F1-model_v2 AlphaFold D3ZQ25 1-705 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695575
Promoter ID:EPDNEW_R6090
Type:multiple initiation site
Name:Fbln1_1
Description:fibulin 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.07126,096,837 - 126,096,897EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308667 AgrOrtholog
BioCyc Gene G2FUF-32556 BioCyc
Ensembl Genes ENSRNOG00000014137 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000047234 ENTREZGENE
  ENSRNOT00000047234.5 UniProtKB/TrEMBL
  ENSRNOT00000088042.2 UniProtKB/TrEMBL
  ENSRNOT00000102556.1 UniProtKB/TrEMBL
  ENSRNOT00000136577 ENTREZGENE
Gene3D-CATH Laminin UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9029287 IMAGE-MGC_LOAD
InterPro Anaphylatoxin/fibulin UniProtKB/TrEMBL
  cEGF UniProtKB/TrEMBL
  ECM_structural_protein UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_Ca-bd UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Fibulin-1 UniProtKB/TrEMBL
  Fibulin_C UniProtKB/TrEMBL
  Growth_fac_rcpt_N_dom UniProtKB/TrEMBL
  Nephronectin_domain UniProtKB/TrEMBL
  NOTCH1_EGF-like UniProtKB/TrEMBL
KEGG Report rno:315191 UniProtKB/TrEMBL
MGC_CLONE MGC:187782 IMAGE-MGC_LOAD
NCBI Gene 315191 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR E1 UniProtKB/TrEMBL
  EGF-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  FIBRILLIN-1 UniProtKB/TrEMBL
  PA14 DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam ANATO UniProtKB/TrEMBL
  cEGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  Fibulin_C UniProtKB/TrEMBL
PhenoGen Fbln1 PhenoGen
PIRSF Fibulin-1 UniProtKB/TrEMBL
PROSITE ANAPHYLATOXIN_1 UniProtKB/TrEMBL
  ANAPHYLATOXIN_2 UniProtKB/TrEMBL
  ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014137 RatGTEx
SMART ANATO UniProtKB/TrEMBL
  EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
UniProt A0A0G2JY81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAN5_RAT UniProtKB/TrEMBL
  A6HTD8 ENTREZGENE, UniProtKB/TrEMBL
  B1WC21 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQ25 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Fbln1  fibulin 1  LOC100362423  Fbln1 protein-like  Data merged from RGD:2318165 737654 PROVISIONAL
2010-05-05 LOC100362423  Fbln1 protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Fbln1  fibulin 1   Fbln1_predicted  fibulin 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fbln1_predicted  fibulin 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED