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Gene: Lrrc47 (leucine rich repeat containing 47) Rattus norvegicus

Analyze

Symbol:

Lrrc47

Name:

leucine rich repeat containing 47

RGD ID:

1308599

Description:

Predicted to enable RNA binding activity. Predicted to contribute to phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation. Orthologous to human LRRC47 (leucine rich repeat containing 47); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,4,7,8-Pentachlorodibenzofuran; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

leucine-rich repeat-containing protein 47; LOC362672; RGD1308599; similar to KIAA1185 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LRRC47 (leucine rich repeat containing 47)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Lrrc47 (leucine rich repeat containing 47)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lrrc47 (leucine rich repeat containing 47)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LRRC47 (leucine rich repeat containing 47)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LRRC47 (leucine rich repeat containing 47)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lrrc47 (leucine rich repeat containing 47)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LRRC47 (leucine rich repeat containing 47)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LRRC47 (leucine rich repeat containing 47)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lrrc47 (leucine rich repeat containing 47)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Lrrc47 (leucine rich repeat containing 47)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	LRRC47 (leucine rich repeat containing 47)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lrrc47 (leucine rich repeat containing 47)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y54E10A.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	lrrc47	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	169,852,926 - 169,862,598 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	169,852,897 - 169,862,598 (+)	Ensembl				GRCr8
mRatBN7.2	5	164,570,539 - 164,580,174 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	164,570,435 - 164,580,174 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	167,274,646 - 167,284,281 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	169,096,056 - 169,105,691 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	169,058,504 - 169,068,139 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	171,297,850 - 171,307,682 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	171,297,850 - 171,307,682 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	174,789,385 - 174,799,217 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	170,798,638 - 170,808,075 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	162,782,523 - 162,792,158 (+)	NCBI		Celera
RGSC_v3.1	5	170,809,132 - 170,817,648 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 1p36 deletion syndrome (ISO)

Ehlers-Danlos syndrome spondylodysplastic type 2 (ISO)

Goldberg-Shprintzen syndrome (ISO)

immunodeficiency 16 (ISO)

immunodeficiency 38 (ISO)

Joubert syndrome 25 (ISO)

Neurodevelopmental Disorders (ISO)

Peroxisome Biogenesis Disorder, Complementation Group 7 (ISO)

Shprintzen-Goldberg Craniosynostosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-colchicine (ISO)

17alpha-ethynylestradiol (EXP)

2,3,4,7,8-Pentachlorodibenzofuran (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dinitrotoluene (EXP)

2,6-dimethoxyphenol (ISO)

4,4'-sulfonyldiphenol (ISO)

adenine (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

caffeine (ISO)

cantharidin (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

coumarin (ISO)

Dibutyl phosphate (ISO)

disodium selenite (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethyl methanesulfonate (ISO)

etoposide (ISO)

FR900359 (ISO)

furfural (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

hydroxyurea (ISO)

ivermectin (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methyl methanesulfonate (ISO)

mitomycin C (ISO)

paracetamol (EXP,ISO)

pentachlorophenol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

resveratrol (ISO)

selenium atom (ISO)

sevoflurane (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloromethane (EXP,ISO)

trichloroethene (EXP)

triptonide (ISO)

vinclozolin (EXP)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

phenylalanyl-tRNA aminoacylation (IEA)

Molecular Function

phenylalanine-tRNA ligase activity (IBA,IEA)

protein binding (ISO)

RNA binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15632090	PMID:22681889	PMID:25931508

Genomics

Comparative Map Data

Lrrc47
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	169,852,926 - 169,862,598 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	5	169,852,897 - 169,862,598 (+)	Ensembl				GRCr8
mRatBN7.2	5	164,570,539 - 164,580,174 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	164,570,435 - 164,580,174 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	5	167,274,646 - 167,284,281 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	169,096,056 - 169,105,691 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	169,058,504 - 169,068,139 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	171,297,850 - 171,307,682 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	171,297,850 - 171,307,682 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	5	174,789,385 - 174,799,217 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	5	170,798,638 - 170,808,075 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	5	162,782,523 - 162,792,158 (+)	NCBI		Celera
RGSC_v3.1	5	170,809,132 - 170,817,648 (+)	NCBI
Cytogenetic Map	5	q36	NCBI

LRRC47
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	3,778,559 - 3,796,498 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	3,778,559 - 3,796,498 (-)	Ensembl			hg38	GRCh38
GRCh37	1	3,695,123 - 3,713,062 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	3,686,644 - 3,702,928 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	2,950,824 - 2,967,113 (-)	NCBI		Celera
Cytogenetic Map	1	p36.32	NCBI
HuRef	1	2,991,976 - 3,008,273 (-)	NCBI		HuRef
CHM1_1	1	3,683,800 - 3,700,087 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	3,290,152 - 3,308,095 (-)	NCBI		T2T-CHM13v2.0

Lrrc47
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	154,096,260 - 154,105,969 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	154,096,188 - 154,105,970 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	4	154,011,803 - 154,021,512 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	154,011,731 - 154,021,513 (+)	Ensembl			mm10	GRCm38
MGSCv37	4	153,385,912 - 153,395,621 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	4	152,855,603 - 152,865,312 (+)	NCBI		MGSCv36	mm8
Celera	4	156,299,232 - 156,308,982 (+)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	83.79	NCBI

Lrrc47
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	7,880,259 - 7,889,274 (+)	Ensembl
ChiLan1.0	NW_004955486	7,880,259 - 7,890,709 (+)	NCBI	ChiLan1.0	ChiLan1.0

LRRC47
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	224,512,320 - 224,528,635 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	223,156,378 - 223,172,677 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	2,451,747 - 2,468,043 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	3,573,386 - 3,589,523 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

LRRC47
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	58,286,909 - 58,297,961 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	58,288,392 - 58,297,996 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	58,297,340 - 58,308,300 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	58,494,439 - 58,505,422 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	58,495,866 - 58,505,437 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	58,502,183 - 58,513,143 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	58,371,127 - 58,382,049 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	58,761,350 - 58,772,306 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Lrrc47
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	29,326,815 - 29,336,188 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936737	129,724 - 139,468 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936737	129,781 - 139,139 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LRRC47
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	65,260,793 - 65,271,729 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	6	65,261,990 - 65,271,745 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	59,996,805 - 59,999,528 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LRRC47
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	127,881,446 - 127,896,138 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	127,881,473 - 127,895,959 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666054	32,092,831 - 32,108,227 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lrrc47
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	6,740,983 - 6,750,877 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624818	6,741,029 - 6,749,919 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Lrrc47
17 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	139
Count of miRNA genes:	106
Interacting mature miRNAs:	118
Transcripts:	ENSRNOT00000034284
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	151113452	166875058	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	154828214	166875058	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
631505	Bp103	Blood pressure QTL 103	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	132717196	165560427	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat

Markers in Region

RH144659

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	164,578,818 - 164,578,980 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	171,306,327 - 171,306,488	NCBI	Rnor6.0
Rnor_5.0	5	174,797,862 - 174,798,023	UniSTS	Rnor5.0
RGSC_v3.4	5	170,806,720 - 170,806,881	UniSTS	RGSC3.4
Celera	5	162,790,803 - 162,790,964	UniSTS
RH 3.4 Map	5	1140.9	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH127584

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	164,579,387 - 164,579,582 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	171,306,896 - 171,307,090	NCBI	Rnor6.0
Rnor_5.0	5	174,798,431 - 174,798,625	UniSTS	Rnor5.0
RGSC_v3.4	5	170,807,289 - 170,807,483	UniSTS	RGSC3.4
Celera	5	162,791,372 - 162,791,566	UniSTS
RH 3.4 Map	5	1138.7	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH127811

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	164,579,734 - 164,579,914 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	171,307,243 - 171,307,422	NCBI	Rnor6.0
Rnor_5.0	5	174,798,778 - 174,798,957	UniSTS	Rnor5.0
RGSC_v3.4	5	170,807,636 - 170,807,815	UniSTS	RGSC3.4
Celera	5	162,791,719 - 162,791,898	UniSTS
RH 3.4 Map	5	1141.0	UniSTS
Cytogenetic Map	5	q36	UniSTS

RH129408

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	164,579,399 - 164,579,579 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	171,306,908 - 171,307,087	NCBI	Rnor6.0
Rnor_5.0	5	174,798,443 - 174,798,622	UniSTS	Rnor5.0
RGSC_v3.4	5	170,807,301 - 170,807,480	UniSTS	RGSC3.4
Celera	5	162,791,384 - 162,791,563	UniSTS
RH 3.4 Map	5	1138.3	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	356	192	11	143	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001135666	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063288094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000034284 ⟹ ENSRNOP00000036336

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	5	169,852,897 - 169,862,598 (+)	Ensembl
mRatBN7.2 Ensembl	5	164,570,435 - 164,580,174 (+)	Ensembl
Rnor_6.0 Ensembl	5	171,297,850 - 171,307,682 (+)	Ensembl

RefSeq Acc Id:

NM_001135666 ⟹ NP_001129138

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	169,852,963 - 169,862,598 (+)	NCBI
mRatBN7.2	5	164,570,539 - 164,580,174 (+)	NCBI
Rnor_6.0	5	171,297,850 - 171,307,682 (+)	NCBI
Rnor_5.0	5	174,789,385 - 174,799,217 (+)	NCBI
RGSC_v3.4	5	170,798,638 - 170,808,075 (+)	RGD
Celera	5	162,782,523 - 162,792,158 (+)	RGD

Sequence:

show sequence

ATGGCGGCGGCTATGGCAGTGTCCGAGGCCTGGCCAGAGCTGGAGCTGGCGGAGCGCGAGCGAC
GTCGCGAGCTGCTGCTGACTGGGCCTGGGCTGGAGGAGAGGGTGAAGGCGGCGGGCGGGCGGCT
GCCGCCGCGGCTCTTCACGCTACCGCTGCTGCACTACCTCGAGGTAAGCGGCTGCGGCAGTCTG
CGCGCCCCGGGGCCCGGCCTTGCGCAGGGCCTGCCACAGCTGCACAGCCTGGTATTGCGGCGTA
ACGCGCTGGGTCCCGGCCTGAGCCCTGAGCTGGGGCCGCTGCCCGCGCTGCGCGTGCTCGACCT
GTCGGGCAACGCGCTGGAGACGCTACCGCCGGGCGAGGGCCTGGGCCCCGCCGAGCCCCCGGGT
CTGCCGCAGCTACAGAGCCTCAACCTCAGCGGCAACCGCCTGCGCGAGCTGCCCGCCGACCTGG
CGCGCTGCGCCCCTCGCCTGCAGAGCCTCAACCTCACCGGCAACTGCTTGGACTCCTTCCCCGC
CGAACTCTTCCGGCCAGGAGCTCTGCCCCTGCTTAGTGAGCTGGCAGCTGCGGACAACTGCCTG
CGGGAGCTCAGCCCAGACATCGCACACCTGGCTTCGCTCAAGACACTGGATCTCTCTAACAACC
AGCTGACAGAGATCCCTGCTGAACTGGCAGACTGCCCCAAGCTCAAAGAGATCAACTTTCGAGG
GAACAGGCTTCGAGACAAGCGCCTGGAGAAGATGGTGGGTGGCTGCCAGACTAAGTCCATCCTA
GAGTACCTGCGTGCTGGTGGCCGTGGCGGTCGGAGCAAGGGCCGGCAAGAGGGCTCTGAGAAGG
AGGACAGAAAGAAGAAGCGGGATCGGAAGCAGCGTCGGGAGAGTGGGGAGGGCGAGGAGGAAGT
AGCAGACTCAGCCAGGCTGATGCTCAAGGTCTTGCACGTCTCGGAGAACCCCACGCCCCTGACA
GTCAGGGTGAGCCCGGAGGTCAGGGACGTGCGTCCATACATTGTGGGGGCCGTCGTGAGAGGCA
TGGACCTGCAGCCAGGAAATGCACTCCGTCGCTTCCTCAACTCCCAGACGAAGCTCCATGACGA
CCTCTGTGAGAAGAGGACAGCAGCGACCATCGCGACCCATGACCTACAAGCTGTGCGTGGACCC
CTGCTGTATGCAGCGCGGCCTCCAGAGGACCTCAAGATTGTGCCTTTGGGGCGGAAAGAGGCCA
AGGCCAAGGAGCTGGTGCGGCAGCTGCAGCTAGAGGCTGAGGAACAGAGAAAGCAGAAGAAAAG
ACAGAGTGTCTCAGGGCTGCACAGATACCTTCACCTCCTGGATGGGAAGGAGAACTACCCCTGT
CTTGTGGATGCCGAGGGAGACGTGATCTCTTTCCCTCCTATAACAAACAGTGAGAAGACAAAGA
TCAAGAGAACAACCTGCAGTGTGTTCTTGGAAGTGACAAGTGCCACCAGCCTGCAGCTCTGCAA
GGACATCATGGACAGCCTCGTCCTGAAAATGGCAGAACTGAACAAAAGCACTTCAGAAAATAAA
GAGGAAGACATGCTCTCAGGGACAGAGACTGATGCCAGCCATGGGCTTTCTGATCCCAACTTGA
ATCCGAGAGCTGGGAAGGATGGACAGTGCCCCCTGGTGGTGGAGCAGGTCCGAGTGGTGGACCT
GGAAGGCAGCTTGAAAGTGGTGTACCCATCCAAGGCCGACCTGGTCACCCTCCCTCCCTATGTG
ACCGTGGTTCGCTGACGATGGTCCAGGCTGCATCAGTCTGCCCACCTGTGGCTCCTGTAGGTGT
GCTGTAGATGTCTGTGTGACCGGTGGTTGTTCTCCCTTTCACTGGGTGTTTTGAGGTGTCTGCT
TTTGTCCAGGTGACTGTGTGATGTGAATCTGTCATCGTTATAGCTCTGGTATGATCCTCCTGTC
TACTGTCCTCATGGATCATTCAAATAACTGCTGAAAGTGTTCTGAATCATGTGGCCAGTAACTA
GGAGAGGCACCAAGCCTGGTGCGCGCGCTGTGCCCTGTAAGTTCAGGCTGGATGGCAGGCAGTC
TATTGAACGGTATTTATTTTTCTACAACATGTTAATAGCATTTTTTTTCAACATCAGCTGTGCA
AAGACAGTTGAGAGCATCATGTTGTGATCATAGTCTTAGAGCTTGTTTCTGGGCACAGTGCTGC
TGCCATGGTCCTCGGGCAGCATCTGCCTTCCACAGCTGTGCTTCCAACTGGAGTGCTGGTCATT
GTTGGCACATCTGTGCCGGGGCCACAGAAGTCAGCCATGCCCATGTAGTCCTGTGTAGCCAGCC
AGTGGTCTGTGAGTGGGTGGGAAGGCTGGTGTGTGGACTGTCATACGGTAGCTGAGGAAGGAGT
GCCGCCCACCAGGCCCTGCAGGCTCAACACAGCCTGTCTCTCTGTGCATGTGCTGGTGTGTACC
CAGCACACAGCTGCCATTCCTGGAGCCACAGTGCTTGATCCTAAGGACCCAGCCAGCTGCAGAA
AGGACTTGGTGGCCCCATGCCTTACCAGACCTCAGTGGTGGTCTCTGACCTCAAAGGACAATTT
CTATCTTCTGTAAAAGAACGACTGTTGGGGTTGTTTCCGGGTTCTATTCTGTTCTAAGGGTATG
CGAGAGCCTTTAGCTGCCAGATCTAGTGAGGCTCCAGGCCCCTCATGGCAGACCCTGGACAAAG
CTGGTGGTTGTGGCAAAAACTTACCTAAGCGTTTAGGGTGGAGCTGCCCTGTGCCCACCCTGTT
TCTCCCCAGTTCCTGCTCTCCCAAACCTCCATCCAGCACAGCCCCGGTGTGAGACTCATTGAGA
TTTTTGGAACTGTTTTTACATTGCAAGCAGAATGCCTCTTTGTTCTAATAAAACTAATAAAAAA
CCCTTGGTAACAA

hide sequence

RefSeq Acc Id:

XM_063288094 ⟹ XP_063144164

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	169,852,926 - 169,861,072 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001129138	(Get FASTA)	NCBI Sequence Viewer
	XP_063144164	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL81252	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000036336
	ENSRNOP00000036336.5

RefSeq Acc Id:

NP_001129138 ⟸ NM_001135666

- UniProtKB:

F1LT49 (UniProtKB/TrEMBL), A6IUK1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAAMAVSEAWPELELAERERRRELLLTGPGLEERVKAAGGRLPPRLFTLPLLHYLEVSGCGSL
RAPGPGLAQGLPQLHSLVLRRNALGPGLSPELGPLPALRVLDLSGNALETLPPGEGLGPAEPPG
LPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCL
RELSPDIAHLASLKTLDLSNNQLTEIPAELADCPKLKEINFRGNRLRDKRLEKMVGGCQTKSIL
EYLRAGGRGGRSKGRQEGSEKEDRKKKRDRKQRRESGEGEEEVADSARLMLKVLHVSENPTPLT
VRVSPEVRDVRPYIVGAVVRGMDLQPGNALRRFLNSQTKLHDDLCEKRTAATIATHDLQAVRGP
LLYAARPPEDLKIVPLGRKEAKAKELVRQLQLEAEEQRKQKKRQSVSGLHRYLHLLDGKENYPC
LVDAEGDVISFPPITNSEKTKIKRTTCSVFLEVTSATSLQLCKDIMDSLVLKMAELNKSTSENK
EEDMLSGTETDASHGLSDPNLNPRAGKDGQCPLVVEQVRVVDLEGSLKVVYPSKADLVTLPPYV
TVVR

hide sequence

Ensembl Acc Id:

ENSRNOP00000036336 ⟸ ENSRNOT00000034284

RefSeq Acc Id:	XP_063144164 ⟸ XM_063288094
- Peptide Label:	isoform X1

Protein Domains

B3/B4 tRNA-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LT49-F1-model_v2	AlphaFold	F1LT49	1-580	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694307

Promoter ID:

EPDNEW_R4832

Type:

multiple initiation site

Name:

Lrrc47_1

Description:

leucine rich repeat containing 47

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	171,297,836 - 171,297,896	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308599	AgrOrtholog
BioCyc Gene	G2FUF-38973	BioCyc
Ensembl Genes	ENSRNOG00000024796	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034284	ENTREZGENE
	ENSRNOT00000034284.6	UniProtKB/TrEMBL
Gene3D-CATH	3.50.40.10	UniProtKB/TrEMBL
	3.80.10.10	UniProtKB/TrEMBL
InterPro	B3/B4_tRNA-bd	UniProtKB/TrEMBL
	L_dom-like	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_2_copies	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	Phe-tRNA-ligase_IIc_bsu	UniProtKB/TrEMBL
	Phe-tRNA_synthase_B3/B4	UniProtKB/TrEMBL
KEGG Report	rno:362672	UniProtKB/TrEMBL
NCBI Gene	362672	ENTREZGENE
PANTHER	LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47	UniProtKB/TrEMBL
	PTHR10947	UniProtKB/TrEMBL
Pfam	LRR_1	UniProtKB/TrEMBL
	LRR_4	UniProtKB/TrEMBL
	LRR_8	UniProtKB/TrEMBL
PhenoGen	Lrrc47	PhenoGen
PRINTS	LEURICHRPT	UniProtKB/TrEMBL
PROSITE	LRR	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000024796	RatGTEx
SMART	B3_4	UniProtKB/TrEMBL
	LRR_BAC	UniProtKB/TrEMBL
	LRR_TYP	UniProtKB/TrEMBL
Superfamily-SCOP	L domain-like	UniProtKB/TrEMBL
UniProt	A6IUK1	ENTREZGENE, UniProtKB/TrEMBL
	F1LT49	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-04-30	Lrrc47	leucine rich repeat containing 47	Lrrc47_predicted	leucine rich repeat containing 47 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Lrrc47_predicted	leucine rich repeat containing 47 (predicted)	RGD1308599_predicted	similar to KIAA1185 protein (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1308599_predicted	similar to KIAA1185 protein (predicted)	LOC362672_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC362672_predicted	similar to KIAA1185 protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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