Hdhd2 (haloacid dehalogenase-like hydrolase domain containing 2) - Rat Genome Database

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Gene: Hdhd2 (haloacid dehalogenase-like hydrolase domain containing 2) Rattus norvegicus
Analyze
Symbol: Hdhd2
Name: haloacid dehalogenase-like hydrolase domain containing 2
RGD ID: 1308579
Description: Predicted to enable enzyme binding activity and phosphatase activity. Predicted to be involved in protein transport. Predicted to be located in membrane. Predicted to be active in cytoplasm. Orthologous to human HDHD2 (haloacid dehalogenase like hydrolase domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: haloacid dehalogenase-like hydrolase domain-containing protein 2; Ier3ip1; immediate early response 3-interacting protein 1; LOC361351; LRRG00122; RGD1308579; similar to RIKEN cDNA 3110052N05
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81872,763,313 - 72,801,679 (+)NCBIGRCr8
mRatBN7.21870,488,315 - 70,526,471 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1870,474,926 - 70,526,470 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1872,583,994 - 72,628,047 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01873,253,195 - 73,297,248 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01871,109,788 - 71,153,841 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01873,226,630 - 73,278,062 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1873,226,630 - 73,278,337 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01872,904,753 - 72,956,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41873,896,018 - 73,948,475 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11873,982,572 - 74,022,429 (+)NCBI
Celera1869,003,221 - 69,047,712 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA)
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19056867   PMID:22939629   PMID:23533145   PMID:26103128  


Genomics

Comparative Map Data
Hdhd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81872,763,313 - 72,801,679 (+)NCBIGRCr8
mRatBN7.21870,488,315 - 70,526,471 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1870,474,926 - 70,526,470 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1872,583,994 - 72,628,047 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01873,253,195 - 73,297,248 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01871,109,788 - 71,153,841 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01873,226,630 - 73,278,062 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1873,226,630 - 73,278,337 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01872,904,753 - 72,956,254 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41873,896,018 - 73,948,475 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11873,982,572 - 74,022,429 (+)NCBI
Celera1869,003,221 - 69,047,712 (+)NCBICelera
Cytogenetic Map18q12.3NCBI
HDHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381847,107,410 - 47,150,500 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1847,107,408 - 47,150,500 (-)EnsemblGRCh38hg38GRCh38
GRCh371844,633,781 - 44,676,871 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361842,887,779 - 42,930,869 (-)NCBINCBI36Build 36hg18NCBI36
Build 341842,887,778 - 42,930,869NCBI
Celera1841,484,304 - 41,527,393 (-)NCBICelera
Cytogenetic Map18q21.1NCBI
HuRef1841,481,839 - 41,524,935 (-)NCBIHuRef
CHM1_11844,628,953 - 44,672,058 (-)NCBICHM1_1
T2T-CHM13v2.01847,297,708 - 47,340,812 (-)NCBIT2T-CHM13v2.0
Hdhd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391877,031,775 - 77,059,867 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1877,031,788 - 77,063,003 (+)EnsemblGRCm39 Ensembl
GRCm381876,944,115 - 76,972,171 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1876,944,092 - 76,975,307 (+)EnsemblGRCm38mm10GRCm38
MGSCv371877,182,854 - 77,210,910 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361877,148,565 - 77,176,621 (+)NCBIMGSCv36mm8
Celera1878,128,025 - 78,155,811 (+)NCBICelera
Cytogenetic Map18E3NCBI
cM Map1851.98NCBI
Hdhd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540232,494,824 - 32,529,233 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540232,495,053 - 32,529,284 (-)NCBIChiLan1.0ChiLan1.0
HDHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21764,642,754 - 64,685,887 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11850,335,355 - 50,378,487 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01840,495,385 - 40,538,527 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11843,855,696 - 43,898,794 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1843,855,696 - 43,898,765 (-)Ensemblpanpan1.1panPan2
HDHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1744,328,108 - 44,364,395 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl744,328,128 - 44,363,270 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha743,812,446 - 43,848,743 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0744,281,518 - 44,317,858 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl744,281,566 - 44,317,858 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1743,981,583 - 44,017,871 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0744,035,647 - 44,071,931 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0744,319,404 - 44,355,709 (+)NCBIUU_Cfam_GSD_1.0
Hdhd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494440,553,326 - 40,594,655 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493698377,858 - 119,108 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493698377,844 - 119,137 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HDHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl196,671,793 - 96,729,441 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1196,682,632 - 96,729,510 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21309,603,391 - 309,650,254 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HDHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11833,793,661 - 33,842,397 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1833,815,017 - 33,841,508 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660508,098,481 - 8,147,572 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hdhd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477810,657,801 - 10,704,043 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477810,655,560 - 10,703,759 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hdhd2
135 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:189
Count of miRNA genes:148
Interacting mature miRNAs:163
Transcripts:ENSRNOT00000024378, ENSRNOT00000051857
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
12904069Cm123Cardiac mass QTL 1230.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)185253976376104388Rat
12904070Cm124Cardiac mass QTL 1240.01heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)185253976376104388Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
12904071Am18Aortic mass QTL 180.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)185253976376104388Rat
12904067Cm122Cardiac mass QTL 1220.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)185253976376104388Rat
61384Bp48Blood pressure QTL 4819.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)186062231177209844Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
2301417Bp319Blood pressure QTL 3190.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185253976376104388Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
12904073Kidm71Kidney mass QTL 710.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)185253976376104388Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)185979647883828827Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185146473383218561Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647883828827Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
70185BpQTLcluster15Blood pressure QTL cluster 154.61arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)185971241776477814Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
1331770Bp234Blood pressure QTL 2343.807arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647871893566Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
2301969Bp324Blood pressure QTL 3244.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)185971241776477814Rat
631675Iddm15Insulin dependent diabetes mellitus QTL 15urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)186062231177209844Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
12880368Bw187Body weight QTL 1870.045body mass (VT:0001259)body weight (CMO:0000012)185253976376104388Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)185917211583828827Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1359020Ppulsi2Prepulse inhibition QTL 22.71prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)185229287573997283Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat

Markers in Region
RH130770  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21870,485,845 - 70,486,034 (+)MAPPERmRatBN7.2
Rnor_6.01873,236,919 - 73,237,107NCBIRnor6.0
Rnor_5.01872,915,042 - 72,915,230UniSTSRnor5.0
RGSC_v3.41873,906,833 - 73,907,021UniSTSRGSC3.4
Celera1869,014,030 - 69,014,218UniSTS
RH 3.4 Map18747.4UniSTS
Cytogenetic Map18q12.3UniSTS
RH131686  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21870,525,541 - 70,525,754 (+)MAPPERmRatBN7.2
Rnor_6.01873,277,408 - 73,277,620NCBIRnor6.0
Rnor_5.01872,955,531 - 72,955,743UniSTSRnor5.0
RGSC_v3.41873,948,736 - 73,948,948UniSTSRGSC3.4
Celera1869,047,973 - 69,048,185UniSTS
RH 3.4 Map18748.2UniSTS
Cytogenetic Map18q12.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000051857   ⟹   ENSRNOP00000039553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,474,926 - 70,526,470 (+)Ensembl
Rnor_6.0 Ensembl1873,226,630 - 73,277,147 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080660   ⟹   ENSRNOP00000075095
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,488,303 - 70,526,470 (+)Ensembl
Rnor_6.0 Ensembl1873,256,085 - 73,278,337 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080784   ⟹   ENSRNOP00000070931
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,488,315 - 70,525,963 (+)Ensembl
Rnor_6.0 Ensembl1873,239,386 - 73,277,828 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099984   ⟹   ENSRNOP00000079408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,501,941 - 70,504,546 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102181   ⟹   ENSRNOP00000087273
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,475,037 - 70,484,058 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110162   ⟹   ENSRNOP00000086673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,488,303 - 70,515,782 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114887   ⟹   ENSRNOP00000088360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,474,956 - 70,485,994 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119462   ⟹   ENSRNOP00000080458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1870,474,926 - 70,504,546 (+)Ensembl
RefSeq Acc Id: NM_001412497   ⟹   NP_001399426
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81872,763,313 - 72,801,679 (+)NCBI
mRatBN7.21870,488,315 - 70,526,471 (+)NCBI
RefSeq Acc Id: NM_001412498   ⟹   NP_001399427
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81872,777,343 - 72,801,679 (+)NCBI
mRatBN7.21870,502,132 - 70,526,471 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001399426 (Get FASTA)   NCBI Sequence Viewer  
  NP_001399427 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH78941 (Get FASTA)   NCBI Sequence Viewer  
  EDL84723 (Get FASTA)   NCBI Sequence Viewer  
  EDL84724 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000075095
  ENSRNOP00000075095.1
GenBank Protein Q6AYR6 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000070931   ⟸   ENSRNOT00000080784
Ensembl Acc Id: ENSRNOP00000075095   ⟸   ENSRNOT00000080660
Ensembl Acc Id: ENSRNOP00000039553   ⟸   ENSRNOT00000051857
Ensembl Acc Id: ENSRNOP00000088360   ⟸   ENSRNOT00000114887
Ensembl Acc Id: ENSRNOP00000087273   ⟸   ENSRNOT00000102181
Ensembl Acc Id: ENSRNOP00000079408   ⟸   ENSRNOT00000099984
Ensembl Acc Id: ENSRNOP00000080458   ⟸   ENSRNOT00000119462
Ensembl Acc Id: ENSRNOP00000086673   ⟸   ENSRNOT00000110162
RefSeq Acc Id: NP_001399426   ⟸   NM_001412497
- UniProtKB: Q6AYR6 (UniProtKB/Swiss-Prot),   A0A8L2R4Y3 (UniProtKB/TrEMBL),   A6KMT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001399427   ⟸   NM_001412498
- UniProtKB: Q6AYR6 (UniProtKB/Swiss-Prot),   A0A8L2R4Y3 (UniProtKB/TrEMBL),   A6KMT8 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P85007-F1-model_v2 AlphaFold P85007 1-82 view protein structure
AF-Q6AYR6-F1-model_v2 AlphaFold Q6AYR6 1-259 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700876
Promoter ID:EPDNEW_R11399
Type:initiation region
Name:Hdhd2_1
Description:haloacid dehalogenase-like hydrolase domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11400  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01873,226,600 - 73,226,660EPDNEW
RGD ID:13700879
Promoter ID:EPDNEW_R11400
Type:initiation region
Name:Hdhd2_2
Description:haloacid dehalogenase-like hydrolase domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11399  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01873,239,367 - 73,239,427EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308579 AgrOrtholog
BioCyc Gene G2FUF-6950 BioCyc
Ensembl Genes ENSRNOG00000043171 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000080660 ENTREZGENE
  ENSRNOT00000080660.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.1000 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7109225 IMAGE-MGC_LOAD
InterPro HAD-like_sf UniProtKB/Swiss-Prot
  HAD-SF_hydro_IIA UniProtKB/Swiss-Prot
  HAD_sf UniProtKB/Swiss-Prot
  LHPP/HDHD2 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93775 IMAGE-MGC_LOAD
NCBI Gene 361351 ENTREZGENE
PANTHER 4-NITROPHENYLPHOSPHATASE-RELATED UniProtKB/Swiss-Prot
  HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/Swiss-Prot
Pfam Hydrolase_6 UniProtKB/Swiss-Prot
  Hydrolase_like UniProtKB/Swiss-Prot
PhenoGen Hdhd2 PhenoGen
RatGTEx ENSRNOG00000043171 RatGTEx
Superfamily-SCOP SSF56784 UniProtKB/Swiss-Prot
UniProt A0A8I5ZMN3_RAT UniProtKB/TrEMBL
  A0A8I5ZPV4_RAT UniProtKB/TrEMBL
  A0A8I6A2N5_RAT UniProtKB/TrEMBL
  A0A8I6GEZ2_RAT UniProtKB/TrEMBL
  A0A8L2R4Y3 ENTREZGENE, UniProtKB/TrEMBL
  A6KMT8 ENTREZGENE, UniProtKB/TrEMBL
  HDHD2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6QI86_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-26 Hdhd2  haloacid dehalogenase-like hydrolase domain containing 2  RGD1308579  similar to RIKEN cDNA 3110052N05  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1308579  similar to RIKEN cDNA 3110052N05  RGD1308579_predicted  similar to RIKEN cDNA 3110052N05 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1308579_predicted  similar to RIKEN cDNA 3110052N05 (predicted)  LOC361351_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361351_predicted  similar to RIKEN cDNA 3110052N05 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL