Rpl7l1 (ribosomal protein L7-like 1) - Rat Genome Database

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Gene: Rpl7l1 (ribosomal protein L7-like 1) Rattus norvegicus
Analyze
Symbol: Rpl7l1
Name: ribosomal protein L7-like 1
RGD ID: 1308469
Description: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within blastocyst formation. Predicted to be located in nucleolus. Predicted to be part of cytosolic large ribosomal subunit. Orthologous to human RPL7L1 (ribosomal protein L7 like 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 60S ribosomal protein L7-like 1; LOC317275; RGD1308469; ribosomal protein uL30-like; similar to RIKEN cDNA 1500016H10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,695,718 - 21,703,736 (+)NCBIGRCr8
mRatBN7.2914,198,101 - 14,206,119 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,198,092 - 14,206,110 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,780,067 - 22,788,075 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,843,543 - 27,851,566 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,143,439 - 26,151,447 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,508,477 - 16,516,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,508,799 - 16,513,120 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,415,774 - 15,423,796 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.499,394,522 - 9,401,666 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.199,392,588 - 9,399,564 (+)NCBI
Celera911,946,194 - 11,954,220 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:22658674   PMID:22681889   PMID:23211737   PMID:27869233  


Genomics

Comparative Map Data
Rpl7l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8921,695,718 - 21,703,736 (+)NCBIGRCr8
mRatBN7.2914,198,101 - 14,206,119 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl914,198,092 - 14,206,110 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx922,780,067 - 22,788,075 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0927,843,543 - 27,851,566 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0926,143,439 - 26,151,447 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0916,508,477 - 16,516,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl916,508,799 - 16,513,120 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0915,415,774 - 15,423,796 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.499,394,522 - 9,401,666 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.199,392,588 - 9,399,564 (+)NCBI
Celera911,946,194 - 11,954,220 (+)NCBICelera
Cytogenetic Map9q12NCBI
RPL7L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38642,879,616 - 42,889,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl642,879,616 - 42,889,925 (+)EnsemblGRCh38hg38GRCh38
GRCh37642,847,354 - 42,857,638 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36642,955,649 - 42,962,709 (+)NCBINCBI36Build 36hg18NCBI36
Celera644,399,935 - 44,406,997 (+)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef642,565,371 - 42,572,433 (+)NCBIHuRef
CHM1_1642,850,140 - 42,857,206 (+)NCBICHM1_1
T2T-CHM13v2.0642,708,334 - 42,718,617 (+)NCBIT2T-CHM13v2.0
Rpl7l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391747,084,833 - 47,093,582 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1747,084,833 - 47,093,598 (-)EnsemblGRCm39 Ensembl
GRCm381746,773,907 - 46,782,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1746,773,907 - 46,782,672 (-)EnsemblGRCm38mm10GRCm38
MGSCv371746,910,856 - 46,919,605 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361746,237,098 - 46,245,847 (-)NCBIMGSCv36mm8
Celera1750,210,119 - 50,218,866 (-)NCBICelera
Cytogenetic Map17CNCBI
cM Map1722.9NCBI
Rpl7l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554378,903,274 - 8,908,717 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554378,903,274 - 8,916,598 (+)NCBIChiLan1.0ChiLan1.0
RPL7L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2557,375,976 - 57,385,233 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1653,246,171 - 53,255,245 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0642,469,047 - 42,479,329 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1643,763,835 - 43,771,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl643,763,835 - 43,771,390 (+)Ensemblpanpan1.1panPan2
RPL7L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11211,445,225 - 11,451,147 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1211,472,191 - 11,478,113 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01211,926,574 - 11,931,932 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1211,926,569 - 11,933,644 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11211,454,463 - 11,459,820 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01211,538,765 - 11,544,126 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01211,632,789 - 11,638,147 (+)NCBIUU_Cfam_GSD_1.0
Rpl7l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494646,929,335 - 46,937,836 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647617,017,950 - 17,030,857 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647617,022,292 - 17,030,534 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPL7L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl737,940,834 - 37,951,324 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1737,940,549 - 37,948,258 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2743,388,916 - 43,396,626 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPL7L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11729,261,400 - 29,272,240 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1729,262,846 - 29,272,245 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604442,915,342 - 42,926,088 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rpl7l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475416,564,316 - 16,573,900 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475416,568,739 - 16,573,790 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rpl7l1
37 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:55
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000021803
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat

Markers in Region
RH133185  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,204,552 - 14,204,717 (+)MAPPERmRatBN7.2
Rnor_6.0916,514,936 - 16,515,100NCBIRnor6.0
Rnor_5.0915,422,230 - 15,422,394UniSTSRnor5.0
RGSC_v3.499,400,686 - 9,400,850UniSTSRGSC3.4
Celera911,952,654 - 11,952,818UniSTS
RH 3.4 Map958.5UniSTS
Cytogenetic Map9q12UniSTS
AW526165  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2914,204,895 - 14,205,055 (+)MAPPERmRatBN7.2
mRatBN7.2X40,883,604 - 40,883,764 (+)MAPPERmRatBN7.2
Rnor_6.0X44,158,685 - 44,158,844NCBIRnor6.0
Rnor_6.0916,515,279 - 16,515,438NCBIRnor6.0
Rnor_5.0915,422,573 - 15,422,732UniSTSRnor5.0
Rnor_5.0X44,458,810 - 44,458,969UniSTSRnor5.0
RGSC_v3.499,401,029 - 9,401,188UniSTSRGSC3.4
Celera911,952,997 - 11,953,156UniSTS
CeleraX41,543,641 - 41,543,800UniSTS
RH 3.4 Map959.7UniSTS
Cytogenetic Map9q12UniSTS
RH135088  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000021803   ⟹   ENSRNOP00000021803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl914,198,092 - 14,206,110 (+)Ensembl
Rnor_6.0 Ensembl916,508,799 - 16,513,120 (+)Ensembl
RefSeq Acc Id: NM_001399334   ⟹   NP_001386263
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8921,695,718 - 21,703,736 (+)NCBI
mRatBN7.2914,198,101 - 14,206,119 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001386263 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM18863 (Get FASTA)   NCBI Sequence Viewer  
  EDM18864 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000021803
  ENSRNOP00000021803.5
RefSeq Acc Id: ENSRNOP00000021803   ⟸   ENSRNOT00000021803
RefSeq Acc Id: NP_001386263   ⟸   NM_001399334
- UniProtKB: D4A1K2 (UniProtKB/TrEMBL),   A6JIL8 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A1K2-F1-model_v2 AlphaFold D4A1K2 1-246 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696504
Promoter ID:EPDNEW_R7027
Type:multiple initiation site
Name:Rpl7l1_1
Description:ribosomal protein L7-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0916,508,778 - 16,508,838EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308469 AgrOrtholog
BioCyc Gene G2FUF-28248 BioCyc
Ensembl Genes ENSRNOG00000016269 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021803 ENTREZGENE
  ENSRNOT00000021803.8 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1390.20 UniProtKB/TrEMBL
InterPro L30_ferredoxin-like_sf UniProtKB/TrEMBL
  Ribosomal_L30_CS UniProtKB/TrEMBL
  Ribosomal_L30_ferredoxin-like UniProtKB/TrEMBL
  Ribosomal_L30_N UniProtKB/TrEMBL
  Ribosomal_L7/L30 UniProtKB/TrEMBL
  Ribosomal_L7_euk UniProtKB/TrEMBL
  Ribosomal_L7_euk_arc UniProtKB/TrEMBL
KEGG Report rno:317275 UniProtKB/TrEMBL
NCBI Gene 317275 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L7-LIKE 1 UniProtKB/TrEMBL
  PTHR11524 UniProtKB/TrEMBL
Pfam Ribosomal_L30 UniProtKB/TrEMBL
  Ribosomal_L30_N UniProtKB/TrEMBL
PhenoGen Rpl7l1 PhenoGen
PROSITE RIBOSOMAL_L30 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016269 RatGTEx
Superfamily-SCOP Ribosomal_L30 UniProtKB/TrEMBL
UniProt A6JIL8 ENTREZGENE, UniProtKB/TrEMBL
  D4A1K2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-26 Rpl7l1  ribosomal protein L7-like 1  RGD1308469_predicted  similar to RIKEN cDNA 1500016H10 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1308469_predicted  similar to RIKEN cDNA 1500016H10 (predicted)  LOC317275_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC317275_predicted  similar to RIKEN cDNA 1500016H10 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL