Tmx1 (thioredoxin-related transmembrane protein 1) - Rat Genome Database

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Gene: Tmx1 (thioredoxin-related transmembrane protein 1) Rattus norvegicus
Analyze
Symbol: Tmx1
Name: thioredoxin-related transmembrane protein 1
RGD ID: 1308455
Description: Predicted to enable enzyme inhibitor activity; protein disulfide isomerase activity; and protein-disulfide reductase activity. Predicted to be involved in several processes, including negative regulation of platelet aggregation; negative regulation of triglyceride biosynthetic process; and positive regulation of ERAD pathway. Predicted to be active in endoplasmic reticulum membrane and mitochondria-associated endoplasmic reticulum membrane contact site. Orthologous to human TMX1 (thioredoxin related transmembrane protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362751; thioredoxin domain containing 1; Txndc1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8694,696,699 - 94,707,751 (+)NCBIGRCr8
GRCr8 Ensembl694,696,358 - 94,708,618 (+)EnsemblGRCr8 Ensembl
mRatBN7.2688,960,691 - 88,971,744 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,960,695 - 88,971,301 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx689,352,744 - 89,363,806 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0689,652,189 - 89,663,251 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,091,717 - 89,102,779 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,864,123 - 92,875,141 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,864,123 - 92,874,204 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06102,311,253 - 102,322,281 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4692,562,592 - 92,572,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera687,447,253 - 87,457,339 (+)NCBICelera
RGSC_v3.1692,566,047 - 92,576,094 (+)NCBI
Cytogenetic Map6q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aconitine  (EXP)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cobalt dichloride  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
finasteride  (EXP)
flutamide  (EXP)
FR900359  (ISO)
gentamycin  (EXP)
isoprenaline  (ISO)
ivermectin  (ISO)
kojic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (EXP)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
piperonyl butoxide  (ISO)
piroxicam  (ISO)
poly(I:C)  (EXP)
propiconazole  (ISO)
quercitrin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
testosterone  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11152479   PMID:12477932   PMID:22228764  


Genomics

Comparative Map Data
Tmx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8694,696,699 - 94,707,751 (+)NCBIGRCr8
GRCr8 Ensembl694,696,358 - 94,708,618 (+)EnsemblGRCr8 Ensembl
mRatBN7.2688,960,691 - 88,971,744 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl688,960,695 - 88,971,301 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx689,352,744 - 89,363,806 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0689,652,189 - 89,663,251 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0689,091,717 - 89,102,779 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0692,864,123 - 92,875,141 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl692,864,123 - 92,874,204 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06102,311,253 - 102,322,281 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4692,562,592 - 92,572,638 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera687,447,253 - 87,457,339 (+)NCBICelera
RGSC_v3.1692,566,047 - 92,576,094 (+)NCBI
Cytogenetic Map6q24NCBI
TMX1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381451,240,247 - 51,257,655 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1451,240,162 - 51,257,655 (+)EnsemblGRCh38hg38GRCh38
GRCh371451,706,965 - 51,724,373 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361450,776,636 - 50,794,123 (+)NCBINCBI36Build 36hg18NCBI36
Build 341450,776,685 - 50,792,512NCBI
Celera1431,573,863 - 31,591,352 (+)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1431,866,596 - 31,884,390 (+)NCBIHuRef
CHM1_11451,645,399 - 51,662,884 (+)NCBICHM1_1
T2T-CHM13v2.01445,446,717 - 45,464,426 (+)NCBIT2T-CHM13v2.0
Tmx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391270,499,928 - 70,514,398 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1270,499,869 - 70,514,814 (+)EnsemblGRCm39 Ensembl
GRCm381270,453,154 - 70,467,624 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1270,453,095 - 70,468,040 (+)EnsemblGRCm38mm10GRCm38
MGSCv371271,554,141 - 71,568,611 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361271,371,759 - 71,386,229 (+)NCBIMGSCv36mm8
Celera1271,558,987 - 71,573,471 (+)NCBICelera
Cytogenetic Map12C2NCBI
cM Map1229.13NCBI
Tmx1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540911,710,646 - 11,722,342 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540911,708,867 - 11,722,205 (-)NCBIChiLan1.0ChiLan1.0
TMX1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21552,378,563 - 52,394,539 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11451,595,079 - 51,612,555 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01431,844,418 - 31,861,911 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11450,129,565 - 50,146,148 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1450,129,568 - 50,147,057 (+)Ensemblpanpan1.1panPan2
TMX1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1827,541,407 - 27,556,058 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl827,541,460 - 27,554,681 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha827,294,348 - 27,309,006 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0827,720,393 - 27,735,066 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl827,720,419 - 27,735,066 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1827,375,197 - 27,389,859 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0827,449,389 - 27,464,067 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0827,796,517 - 27,811,194 (+)NCBIUU_Cfam_GSD_1.0
Tmx1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864059,744,345 - 59,759,804 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649514,431,137 - 14,447,476 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649514,432,971 - 14,447,380 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMX1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1180,933,859 - 180,951,341 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11180,933,678 - 180,950,826 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21201,220,189 - 201,235,370 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMX1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12428,334,017 - 28,350,571 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2428,333,357 - 28,352,457 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605316,656,245 - 16,672,417 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmx1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473117,718,868 - 17,730,586 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473117,713,812 - 17,730,521 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmx1
27 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:671
Count of miRNA genes:281
Interacting mature miRNAs:343
Transcripts:ENSRNOT00000009587
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
4889933Bss88Bone structure and strength QTL 883.8tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)65368492198684921Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
5684992Bmd83Bone mineral density QTL 824.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)65368492198684921Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)686494122112380234Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)671278722116278722Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)664367996109367996Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)66345744194939581Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)646050607116278722Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2293837Kiddil1Kidney dilation QTL 13.7kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
2293842Kiddil3Kidney dilation QTL 34.3kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)686867923110125012Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)66303731995934232Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
5684963Bss99Bone structure and strength QTL 993.1tibia area (VT:1000281)tibia area measurement (CMO:0001382)65368492198684921Rat
1576302Schws4Schwannoma susceptibility QTL 40.0078nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)678204640123204640Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)676937178121937178Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)66345744194939581Rat

Markers in Region
RH134372  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2688,971,018 - 88,971,206 (+)MAPPERmRatBN7.2
Rnor_6.0692,874,416 - 92,874,603NCBIRnor6.0
Rnor_5.06102,321,556 - 102,321,743UniSTSRnor5.0
RGSC_v3.4692,572,844 - 92,573,178UniSTSRGSC3.4
Celera687,457,545 - 87,457,732UniSTS
RH 3.4 Map6636.0UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 11 93 45 60 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000087540   ⟹   ENSRNOP00000071802
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,697,980 - 94,707,307 (+)Ensembl
mRatBN7.2 Ensembl688,960,695 - 88,971,301 (+)Ensembl
Rnor_6.0 Ensembl692,864,123 - 92,874,204 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098562   ⟹   ENSRNOP00000086803
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,696,358 - 94,708,618 (+)Ensembl
mRatBN7.2 Ensembl688,961,868 - 88,971,298 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000100740   ⟹   ENSRNOP00000081790
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl694,696,702 - 94,708,618 (+)Ensembl
mRatBN7.2 Ensembl688,960,738 - 88,971,298 (+)Ensembl
RefSeq Acc Id: NM_001024800   ⟹   NP_001019971
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8694,696,699 - 94,707,751 (+)NCBI
mRatBN7.2688,960,691 - 88,971,744 (+)NCBI
Rnor_6.0692,864,123 - 92,874,210 (+)NCBI
Rnor_5.06102,311,253 - 102,322,281 (+)NCBI
RGSC_v3.4692,562,592 - 92,572,638 (+)RGD
Celera687,447,253 - 87,457,339 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240178   ⟹   XP_006240240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8694,697,245 - 94,707,751 (+)NCBI
mRatBN7.2688,961,626 - 88,971,301 (+)NCBI
Rnor_6.0692,864,593 - 92,875,141 (+)NCBI
Rnor_5.06102,311,253 - 102,322,281 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001019971 (Get FASTA)   NCBI Sequence Viewer  
  XP_006240240 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH94308 (Get FASTA)   NCBI Sequence Viewer  
  EDM03551 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071802
  ENSRNOP00000071802.2
  ENSRNOP00000081790
  ENSRNOP00000081790.1
  ENSRNOP00000086803.1
RefSeq Acc Id: NP_001019971   ⟸   NM_001024800
- Peptide Label: precursor
- UniProtKB: Q52KJ9 (UniProtKB/TrEMBL),   A0A0G2K1D9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240240   ⟸   XM_006240178
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A1Z5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071802   ⟸   ENSRNOT00000087540
Ensembl Acc Id: ENSRNOP00000086803   ⟸   ENSRNOT00000098562
Ensembl Acc Id: ENSRNOP00000081790   ⟸   ENSRNOT00000100740
Protein Domains
Thioredoxin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q52KJ9-F1-model_v2 AlphaFold Q52KJ9 1-278 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694643
Promoter ID:EPDNEW_R5167
Type:initiation region
Name:Tmx1_1
Description:thioredoxin-related transmembrane protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0692,864,137 - 92,864,197EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308455 AgrOrtholog
BioCyc Gene G2FUF-37205 BioCyc
Ensembl Genes ENSRNOG00000057934 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000087540 ENTREZGENE
  ENSRNOT00000087540.2 UniProtKB/TrEMBL
  ENSRNOT00000098562.1 UniProtKB/TrEMBL
  ENSRNOT00000100740 ENTREZGENE
  ENSRNOT00000100740.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7316392 IMAGE-MGC_LOAD
InterPro Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_CS UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
  TMX_domain-containing UniProtKB/TrEMBL
KEGG Report rno:362751 UniProtKB/TrEMBL
MGC_CLONE MGC:105752 IMAGE-MGC_LOAD
NCBI Gene 362751 ENTREZGENE
PANTHER DUMPY: SHORTER THAN WILD-TYPE UniProtKB/TrEMBL
  THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 UniProtKB/TrEMBL
Pfam Thioredoxin UniProtKB/TrEMBL
PhenoGen Tmx1 PhenoGen
PROSITE THIOREDOXIN_1 UniProtKB/TrEMBL
  THIOREDOXIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000057934 RatGTEx
Superfamily-SCOP Thiordxn-like_fd UniProtKB/TrEMBL
UniProt A0A0G2K1D9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT91_RAT UniProtKB/TrEMBL
  A0A8I6A1Z5 ENTREZGENE, UniProtKB/TrEMBL
  Q52KJ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Tmx1  thioredoxin-related transmembrane protein 1  Txndc1  thioredoxin domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Txndc1  thioredoxin domain containing 1  Txndc1_predicted  thioredoxin domain containing 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Txndc1_predicted  thioredoxin domain containing 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED