Hars2 (histidyl-tRNA synthetase 2, mitochondrial) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Hars2 (histidyl-tRNA synthetase 2, mitochondrial) Rattus norvegicus
Analyze
Symbol: Hars2 (Ensembl: Zmat2)
Name: histidyl-tRNA synthetase 2, mitochondrial (Ensembl:zinc finger, matrin type 2)
RGD ID: 1308426
Description: Predicted to enable RNA binding activity; histidine-tRNA ligase activity; and identical protein binding activity. Predicted to be involved in histidyl-tRNA aminoacylation. Predicted to be active in cytosol and mitochondrion. Human ortholog(s) of this gene implicated in Perrault syndrome. Orthologous to human HARS2 (histidyl-tRNA synthetase 2, mitochondrial); PARTICIPATES IN histidine metabolic pathway; histidinemia pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Hars2l; histidyl-tRNA synthetase 2; histidyl-tRNA synthetase 2, mitochondrial (putative); histidyl-tRNA synthetase 2-like; LOC307491; MGC109366; probable histidine--tRNA ligase, mitochondrial; RGD1308426; similar to histidyl-tRNA synthetase-like; zinc finger, matrin type 2; Zmat2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,672,810 - 28,682,367 (+)NCBIGRCr8
mRatBN7.21828,398,790 - 28,408,075 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,398,795 - 28,414,747 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,525,979 - 28,535,208 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01829,288,059 - 29,297,284 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,623,283 - 28,632,512 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,629,203 - 29,638,460 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,629,184 - 29,638,721 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01829,332,574 - 29,341,926 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,483,181 - 29,491,738 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11829,514,082 - 29,518,382 (+)NCBI
Celera1828,119,418 - 28,128,621 (+)NCBICelera
Cytogenetic Map18p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:18614015   PMID:21464306   PMID:22681889  


Genomics

Comparative Map Data
Hars2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,672,810 - 28,682,367 (+)NCBIGRCr8
mRatBN7.21828,398,790 - 28,408,075 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,398,795 - 28,414,747 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,525,979 - 28,535,208 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01829,288,059 - 29,297,284 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,623,283 - 28,632,512 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,629,203 - 29,638,460 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,629,184 - 29,638,721 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01829,332,574 - 29,341,926 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,483,181 - 29,491,738 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11829,514,082 - 29,518,382 (+)NCBI
Celera1828,119,418 - 28,128,621 (+)NCBICelera
Cytogenetic Map18p11NCBI
HARS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,691,455 - 140,699,305 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,691,430 - 140,699,305 (+)EnsemblGRCh38hg38GRCh38
GRCh375140,071,040 - 140,078,890 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365140,051,202 - 140,059,074 (+)NCBINCBI36Build 36hg18NCBI36
Build 345140,051,201 - 140,059,073NCBI
Celera5136,147,766 - 136,155,638 (+)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5135,216,262 - 135,224,154 (+)NCBIHuRef
CHM1_15139,504,261 - 139,512,161 (+)NCBICHM1_1
T2T-CHM13v2.05141,216,842 - 141,224,701 (+)NCBIT2T-CHM13v2.0
Hars2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,916,257 - 36,925,615 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,916,061 - 36,925,615 (+)EnsemblGRCm39 Ensembl
GRCm381836,783,202 - 36,792,562 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,783,008 - 36,792,562 (+)EnsemblGRCm38mm10GRCm38
MGSCv371836,942,934 - 36,952,216 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,909,254 - 36,918,536 (+)NCBIMGSCv36mm8
Celera1837,235,296 - 37,244,596 (+)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Hars2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541812,550 - 19,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541812,550 - 19,282 (-)NCBIChiLan1.0ChiLan1.0
LOC100969951
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,949,468 - 135,959,879 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15134,089,019 - 134,096,702 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05136,056,060 - 136,065,588 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15142,172,075 - 142,179,950 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5142,172,081 - 142,179,950 (+)Ensemblpanpan1.1panPan2
HARS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,843,611 - 35,851,257 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,843,706 - 35,850,760 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,882,606 - 32,890,252 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,299,236 - 36,306,899 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,299,284 - 36,306,892 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1233,351,339 - 33,358,986 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,219,342 - 34,227,112 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,972,058 - 34,979,705 (+)NCBIUU_Cfam_GSD_1.0
Hars2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213151,978,877 - 151,986,315 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,624,927 - 9,632,611 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,625,206 - 9,633,463 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HARS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2142,401,328 - 142,409,619 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12142,401,279 - 142,410,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22148,345,465 - 148,353,805 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HARS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12343,323,847 - 43,333,620 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2343,323,892 - 43,331,401 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603434,523,360 - 34,533,110 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hars2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,435,806 - 33,443,227 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,435,777 - 33,443,036 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hars2
25 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:170
Count of miRNA genes:126
Interacting mature miRNAs:150
Transcripts:ENSRNOT00000021797
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
1331735Rf44Renal function QTL 442.981urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)181823456431359530Rat
61382Bp46Blood pressure QTL 4618.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194179131393320Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
61388Bp2Blood pressure QTL 23.23arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)18135374722Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2312568Glom21Glomerulus QTL 2120.005kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)18518585840503530Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
1331766Bp236Blood pressure QTL 2363.022arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181194429931359530Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
631264Scl22Serum cholesterol level QTL 226.2blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)181194179131393320Rat
1331775Bp235Blood pressure QTL 2353.201arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)181823456431359530Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
9589153Insul31Insulin level QTL 317.150.05blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)18142547119Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
2312598Bp340Blood pressure QTL 3400.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)18130558703Rat
2300180Bmd67Bone mineral density QTL 674.80.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)18134291613Rat
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
2293661Bss50Bone structure and strength QTL 504.640.0003lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)18134291613Rat
61375Bp41Blood pressure QTL 412.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)181194429941122201Rat

Markers in Region
RH131148  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21828,407,852 - 28,408,035 (+)MAPPERmRatBN7.2
Rnor_6.01829,638,238 - 29,638,420NCBIRnor6.0
Rnor_5.01829,341,704 - 29,341,886UniSTSRnor5.0
RGSC_v3.41829,491,516 - 29,491,698UniSTSRGSC3.4
Celera1828,128,399 - 28,128,581UniSTS
Cytogenetic Map18p11UniSTS
BG373676  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21828,407,338 - 28,407,493 (+)MAPPERmRatBN7.2
Rnor_6.01829,637,724 - 29,637,878NCBIRnor6.0
Rnor_5.01829,341,190 - 29,341,344UniSTSRnor5.0
RGSC_v3.41829,491,002 - 29,491,156UniSTSRGSC3.4
Celera1828,127,885 - 28,128,039UniSTS
Cytogenetic Map18p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000021516   ⟹   ENSRNOP00000021516
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,409,600 - 28,414,747 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000021797   ⟹   ENSRNOP00000021797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,398,817 - 28,408,062 (+)Ensembl
Rnor_6.0 Ensembl1829,629,184 - 29,638,721 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095646   ⟹   ENSRNOP00000078926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,398,817 - 28,408,062 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097043   ⟹   ENSRNOP00000085580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,401,158 - 28,408,075 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104252   ⟹   ENSRNOP00000090091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,398,811 - 28,413,484 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112291   ⟹   ENSRNOP00000085665
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1828,398,795 - 28,407,560 (+)Ensembl
RefSeq Acc Id: NM_001014012   ⟹   NP_001014034
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81828,672,856 - 28,682,086 (+)NCBI
mRatBN7.21828,398,843 - 28,408,075 (+)NCBI
Rnor_6.01829,629,231 - 29,638,460 (+)NCBI
Rnor_5.01829,332,574 - 29,341,926 (+)NCBI
RGSC_v3.41829,483,181 - 29,491,738 (+)RGD
Celera1828,119,418 - 28,128,621 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254575   ⟹   XP_006254637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81828,672,810 - 28,682,367 (+)NCBI
mRatBN7.21828,398,792 - 28,408,075 (+)NCBI
Rnor_6.01829,629,203 - 29,638,452 (+)NCBI
Rnor_5.01829,332,574 - 29,341,926 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096863   ⟹   XP_038952791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81828,675,624 - 28,682,367 (+)NCBI
mRatBN7.21828,401,613 - 28,408,075 (+)NCBI
RefSeq Acc Id: XM_039096864   ⟹   XP_038952792
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81828,673,036 - 28,682,367 (+)NCBI
mRatBN7.21828,399,022 - 28,408,075 (+)NCBI
RefSeq Acc Id: XR_005496038
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81828,672,828 - 28,680,046 (+)NCBI
mRatBN7.21828,398,790 - 28,405,989 (+)NCBI
RefSeq Acc Id: NP_001014034   ⟸   NM_001014012
- UniProtKB: F1M9C9 (UniProtKB/TrEMBL),   A6J338 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254637   ⟸   XM_006254575
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZM00 (UniProtKB/TrEMBL),   A6J338 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000021797   ⟸   ENSRNOT00000021797
RefSeq Acc Id: XP_038952792   ⟸   XM_039096864
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952791   ⟸   XM_039096863
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000085665   ⟸   ENSRNOT00000112291
Ensembl Acc Id: ENSRNOP00000078926   ⟸   ENSRNOT00000095646
Ensembl Acc Id: ENSRNOP00000090091   ⟸   ENSRNOT00000104252
Ensembl Acc Id: ENSRNOP00000021516   ⟸   ENSRNOT00000021516
Ensembl Acc Id: ENSRNOP00000085580   ⟸   ENSRNOT00000097043
Protein Domains
Aminoacyl-transfer RNA synthetases class-II family   Anticodon-binding   Class II Histidinyl-tRNA synthetase (HisRS)-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M9C9-F1-model_v2 AlphaFold F1M9C9 1-507 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700731
Promoter ID:EPDNEW_R11255
Type:multiple initiation site
Name:Hars2_1
Description:histidyl-tRNA synthetase 2, mitochondrial
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01829,629,210 - 29,629,270EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308426 AgrOrtholog
BioCyc Gene G2FUF-7855 BioCyc
BioCyc Pathway TRNA-CHARGING-PWY [tRNA charging] BioCyc
BioCyc Pathway Image TRNA-CHARGING-PWY BioCyc
Ensembl Genes ENSRNOG00000016087 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021797.6 UniProtKB/TrEMBL
  ENSRNOT00000095646.1 UniProtKB/TrEMBL
  ENSRNOT00000097043.1 UniProtKB/TrEMBL
  ENSRNOT00000104252.1 UniProtKB/TrEMBL
  ENSRNOT00000112291.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.800 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7316402 IMAGE-MGC_LOAD
InterPro aa-tRNA-synth_II UniProtKB/TrEMBL
  aa-tRNA-synth_II/BPL/LPL UniProtKB/TrEMBL
  Anticodon-bd UniProtKB/TrEMBL
  Anticodon-bd_dom_sf UniProtKB/TrEMBL
  His-tRNA-ligase UniProtKB/TrEMBL
  His-tRNA_synth_IIA UniProtKB/TrEMBL
  HisRS-like_core UniProtKB/TrEMBL
  HisRS_anticodon UniProtKB/TrEMBL
  Matrin/U1-like-C_Znf_C2H2 UniProtKB/TrEMBL
  Znf_C2H2_jaz UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:307491 UniProtKB/TrEMBL
MGC_CLONE MGC:109366 IMAGE-MGC_LOAD
NCBI Gene 307491 ENTREZGENE
PANTHER HISTIDINE--TRNA LIGASE, MITOCHONDRIAL UniProtKB/TrEMBL
  HISTIDYL-TRNA SYNTHETASE UniProtKB/TrEMBL
Pfam HGTP_anticodon UniProtKB/TrEMBL
  tRNA-synt_His UniProtKB/TrEMBL
  zf-C2H2_jaz UniProtKB/TrEMBL
PhenoGen Hars2 PhenoGen
PIRSF His-tRNA_synth UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_II UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016087 RatGTEx
SMART ZnF_U1 UniProtKB/TrEMBL
Superfamily-SCOP Class II aaRS ABD-related UniProtKB/TrEMBL
  SSF55681 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8I5ZM00 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A401_RAT UniProtKB/TrEMBL
  A0A8I6AB48_RAT UniProtKB/TrEMBL
  A0A8I6GD20_RAT UniProtKB/TrEMBL
  A6J338 ENTREZGENE, UniProtKB/TrEMBL
  F1M9C9 ENTREZGENE, UniProtKB/TrEMBL
  Q5EB72_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-27 Hars2  histidyl-tRNA synthetase 2, mitochondrial  Hars2  histidyl-tRNA synthetase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-12-02 Hars2  histidyl-tRNA synthetase 2  Hars2  histidyl-tRNA synthetase 2, mitochondrial  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-25 Hars2  histidyl-tRNA synthetase 2, mitochondrial  Hars2  histidyl-tRNA synthetase 2, mitochondrial (putative)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-16 Hars2  histidyl-tRNA synthetase 2, mitochondrial (putative)  Hars2l  histidyl-tRNA synthetase 2-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-13 Hars2l  histidyl-tRNA synthetase 2-like  Zmat2  zinc finger, matrin type 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Zmat2  zinc finger, matrin type 2  RGD1308426  similar to histidyl-tRNA synthetase-like  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1308426  similar to histidyl-tRNA synthetase-like  RGD1308426_predicted  similar to histidyl-tRNA synthetase-like (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1308426_predicted  similar to histidyl-tRNA synthetase-like (predicted)  LOC307491_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC307491_predicted  similar to histidyl-tRNA synthetase-like (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL