Cyb5r2 (cytochrome b5 reductase 2) - Rat Genome Database

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Gene: Cyb5r2 (cytochrome b5 reductase 2) Rattus norvegicus
Analyze
Symbol: Cyb5r2
Name: cytochrome b5 reductase 2
RGD ID: 1308421
Description: Predicted to enable FAD binding activity and cytochrome-b5 reductase activity, acting on NAD(P)H. Predicted to be involved in sterol biosynthetic process. Predicted to be located in membrane. Predicted to be active in mitochondrion. Orthologous to human CYB5R2 (cytochrome b5 reductase 2); PARTICIPATES IN amino sugar metabolic pathway; nucleotide sugar metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: b5R.2; LOC365345; NADH-cytochrome b5 reductase 2; RGD1308421; similar to cytochrome b5 reductase b5R.2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81171,062,083 - 171,076,183 (-)NCBIGRCr8
mRatBN7.21161,655,862 - 161,664,359 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1161,655,864 - 161,664,097 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1169,926,045 - 169,934,325 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01177,112,054 - 177,120,338 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01169,796,675 - 169,804,940 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,971,424 - 171,981,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,971,701 - 171,979,933 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01178,964,826 - 178,979,214 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41165,131,106 - 165,139,340 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11165,241,770 - 165,250,003 (-)NCBI
Celera1159,561,210 - 159,569,444 (-)NCBICelera
Cytogenetic Map1q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA,ISO)
mitochondrion  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10611283   PMID:15709757   PMID:18614015   PMID:21630459   PMID:35820466  


Genomics

Comparative Map Data
Cyb5r2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81171,062,083 - 171,076,183 (-)NCBIGRCr8
mRatBN7.21161,655,862 - 161,664,359 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1161,655,864 - 161,664,097 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1169,926,045 - 169,934,325 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01177,112,054 - 177,120,338 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01169,796,675 - 169,804,940 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01171,971,424 - 171,981,586 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1171,971,701 - 171,979,933 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01178,964,826 - 178,979,214 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41165,131,106 - 165,139,340 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11165,241,770 - 165,250,003 (-)NCBI
Celera1159,561,210 - 159,569,444 (-)NCBICelera
Cytogenetic Map1q33NCBI
CYB5R2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,665,095 - 7,674,267 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,665,100 - 7,677,222 (-)EnsemblGRCh38hg38GRCh38
GRCh37117,686,326 - 7,695,498 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,642,902 - 7,651,397 (-)NCBINCBI36Build 36hg18NCBI36
Celera117,802,280 - 7,810,775 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef117,345,050 - 7,353,545 (-)NCBIHuRef
CHM1_1117,685,280 - 7,693,787 (-)NCBICHM1_1
T2T-CHM13v2.0117,723,469 - 7,735,468 (-)NCBIT2T-CHM13v2.0
Cyb5r2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397107,347,653 - 107,357,407 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7107,347,662 - 107,357,239 (-)EnsemblGRCm39 Ensembl
GRCm387107,748,446 - 107,758,202 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7107,748,455 - 107,758,032 (-)EnsemblGRCm38mm10GRCm38
MGSCv377114,891,969 - 114,901,510 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367107,539,632 - 107,549,173 (-)NCBIMGSCv36mm8
Celera7107,723,685 - 107,733,226 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map757.21NCBI
LOC102011649
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541423,419,788 - 23,428,852 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541423,421,387 - 23,427,883 (-)NCBIChiLan1.0ChiLan1.0
LOC100978149
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2910,065,998 - 10,076,646 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11110,028,587 - 10,039,270 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0117,759,698 - 7,770,382 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,441,287 - 7,463,427 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,441,287 - 7,451,553 (-)Ensemblpanpan1.1panPan2
CYB5R2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12131,315,535 - 31,324,296 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2131,315,552 - 31,324,961 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2130,883,614 - 30,894,187 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02132,178,112 - 32,188,682 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2132,179,939 - 32,189,306 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12131,450,823 - 31,461,387 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02131,614,157 - 31,624,717 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02131,910,205 - 31,920,779 (-)NCBIUU_Cfam_GSD_1.0
LOC101978076
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494754,179,458 - 54,200,031 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936841899,359 - 906,786 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936841890,674 - 907,619 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC110262320
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.191,972,449 - 1,986,426 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CYB5R2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1157,171,203 - 57,180,224 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl157,172,484 - 57,180,576 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038154,902,284 - 154,911,379 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101714255
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248179,381,021 - 9,387,688 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248179,380,383 - 9,387,688 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cyb5r2
49 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:201
Count of miRNA genes:157
Interacting mature miRNAs:167
Transcripts:ENSRNOT00000026744
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
2313060Bss71Bone structure and strength QTL 712.60.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1118944747163944747Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121833674166833674Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1136745990163747690Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1144267916172949660Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144267916174133260Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1155422851172949803Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1156677124176484451Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat

Markers in Region
RH130968  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21161,655,890 - 161,656,089 (+)MAPPERmRatBN7.2
Rnor_6.01171,971,728 - 171,971,926NCBIRnor6.0
Rnor_5.01178,970,132 - 178,970,330UniSTSRnor5.0
RGSC_v3.41165,131,135 - 165,131,333UniSTSRGSC3.4
Celera1159,561,239 - 159,561,437UniSTS
Cytogenetic Map1q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 7 4
Low 3 19 24 8 19 8 8 11 71 35 30 7 8
Below cutoff 22 13 13 13 2 4

Sequence


RefSeq Acc Id: ENSRNOT00000026744   ⟹   ENSRNOP00000026744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1161,655,864 - 161,664,097 (-)Ensembl
Rnor_6.0 Ensembl1171,971,701 - 171,979,933 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079844   ⟹   ENSRNOP00000075603
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1161,655,864 - 161,664,097 (-)Ensembl
Rnor_6.0 Ensembl1171,971,896 - 171,979,757 (-)Ensembl
RefSeq Acc Id: NM_001014244   ⟹   NP_001014266
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81171,067,612 - 171,075,846 (-)NCBI
mRatBN7.21161,655,862 - 161,664,097 (-)NCBI
Rnor_6.01171,971,699 - 171,979,933 (-)NCBI
Rnor_5.01178,964,826 - 178,979,214 (-)NCBI
RGSC_v3.41165,131,106 - 165,139,340 (-)RGD
Celera1159,561,210 - 159,569,444 (-)RGD
Sequence:
RefSeq Acc Id: XM_017589483   ⟹   XP_017444972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81171,067,612 - 171,075,690 (-)NCBI
mRatBN7.21161,655,862 - 161,663,735 (-)NCBI
Rnor_6.01171,971,424 - 171,979,985 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039085166   ⟹   XP_038941094
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81171,067,612 - 171,075,690 (-)NCBI
mRatBN7.21161,655,862 - 161,663,718 (-)NCBI
RefSeq Acc Id: XM_063269340   ⟹   XP_063125410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81171,067,612 - 171,075,857 (-)NCBI
RefSeq Acc Id: XM_063269341   ⟹   XP_063125411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81171,067,612 - 171,076,183 (-)NCBI
RefSeq Acc Id: XM_063269350   ⟹   XP_063125420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81171,062,083 - 171,075,690 (-)NCBI
RefSeq Acc Id: XM_063269352   ⟹   XP_063125422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81171,067,612 - 171,076,176 (-)NCBI
RefSeq Acc Id: XM_063269356   ⟹   XP_063125426
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81171,062,083 - 171,075,857 (-)NCBI
RefSeq Acc Id: NP_001014266   ⟸   NM_001014244
- UniProtKB: Q6AY12 (UniProtKB/Swiss-Prot),   A6I7S6 (UniProtKB/TrEMBL),   A0A8L2QFU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017444972   ⟸   XM_017589483
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QFU7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075603   ⟸   ENSRNOT00000079844
RefSeq Acc Id: ENSRNOP00000026744   ⟸   ENSRNOT00000026744
RefSeq Acc Id: XP_038941094   ⟸   XM_039085166
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QFU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125426   ⟸   XM_063269356
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QFU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125420   ⟸   XM_063269350
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QFU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125411   ⟸   XM_063269341
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QFU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125422   ⟸   XM_063269352
- Peptide Label: isoform X2
- UniProtKB: A0A8L2QFU7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125410   ⟸   XM_063269340
- Peptide Label: isoform X1
- UniProtKB: A0A8L2QFU7 (UniProtKB/TrEMBL)
Protein Domains
FAD-binding FR-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AY12-F1-model_v2 AlphaFold Q6AY12 1-276 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308421 AgrOrtholog
BioCyc Gene G2FUF-57952 BioCyc
Ensembl Genes ENSRNOG00000019751 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026744.8 UniProtKB/TrEMBL
  ENSRNOT00000079844 ENTREZGENE
  ENSRNOT00000079844.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.80 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Translation factors UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7132617 IMAGE-MGC_LOAD
InterPro CBR-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cbr1-like_FAD-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FAD-bd_FR_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Flavoprot_Pyr_Nucl_cyt_Rdtase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FNR_nucleotide-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OxRdtase_FAD/NAD-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Riboflavin_synthase-like_b-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:365345 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94317 IMAGE-MGC_LOAD
NCBI Gene 365345 ENTREZGENE
PANTHER NADH-CYTOCHROME B5 REDUCTASE 2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR19370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FAD_binding_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cyb5r2 PhenoGen
PRINTS CYTB5RDTASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FPNCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE FAD_FR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000019751 RatGTEx
Superfamily-SCOP SSF52343 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF63380 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2KB07_RAT UniProtKB/TrEMBL
  A0A8L2QFU7 ENTREZGENE, UniProtKB/TrEMBL
  A6I7S6 ENTREZGENE, UniProtKB/TrEMBL
  NB5R2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Cyb5r2  cytochrome b5 reductase 2  RGD1308421  similar to cytochrome b5 reductase b5R.2  Symbol and Name updated 1299863 APPROVED
2005-12-06 RGD1308421  similar to cytochrome b5 reductase b5R.2  RGD1308421_predicted  similar to cytochrome b5 reductase b5R.2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1308421_predicted  similar to cytochrome b5 reductase b5R.2 (predicted)  LOC365345_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC365345_predicted  similar to cytochrome b5 reductase b5R.2 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL