(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SIRT3 mRNA] CTD PMID:31150632 (-)-epigallocatechin 3-gallate decreases expression ISO RGD:1318107 6480464 epigallocatechin gallate results in decreased expression of SIRT3 mRNA, epigallocatechin gallate results in decreased expression of SIRT3 protein CTD PMID:29175576 (1->4)-beta-D-glucan multiple interactions ISO RGD:1318107 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SIRT3 mRNA CTD PMID:36331819 (R)-lipoic acid increases expression EXP 6480464 Thioctic Acid results in increased expression of SIRT3 protein CTD PMID:22327056 (R)-lipoic acid multiple interactions EXP 6480464 [Thioctic Acid results in increased expression of [SIRT1 protein co-treated with SIRT3 protein]] which results in decreased acetylation of FOXO3 protein more ... CTD PMID:22327056 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases expression ISO RGD:1318107 6480464 2 more ... CTD PMID:25575267 1,1-dichloroethene decreases expression ISO RGD:1318107 6480464 vinylidene chloride results in decreased expression of SIRT3 mRNA CTD PMID:26682919 1,2-dimethylhydrazine decreases expression ISO RGD:1318107 6480464 1, 2-Dimethylhydrazine results in decreased expression of SIRT3 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:1318107 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SIRT3 mRNA CTD PMID:22206623 1,3,7,9-tetramethyluric acid multiple interactions EXP 6480464 1 more ... CTD PMID:35872049 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of SIRT3 mRNA CTD PMID:17557909 17alpha-ethynylestradiol multiple interactions ISO RGD:1318107 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIRT3 mRNA CTD PMID:17942748 17beta-estradiol decreases expression ISO RGD:1318107 6480464 Estradiol results in decreased expression of SIRT3 mRNA CTD PMID:25575267 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of SIRT3 mRNA CTD PMID:32145629 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1318107 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIRT3 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SIRT3 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1318106 6480464 Tetrachlorodibenzodioxin results in increased expression of SIRT3 mRNA CTD PMID:28011154 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of SIRT3 mRNA CTD PMID:21724226 , PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1318107 6480464 Tetrachlorodibenzodioxin affects the expression of SIRT3 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1318107 6480464 Tetrachlorodibenzodioxin results in decreased expression of SIRT3 mRNA CTD PMID:19770486 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of SIRT3 mRNA CTD PMID:21346803 3,5-diethoxycarbonyl-1,4-dihydrocollidine decreases expression ISO RGD:1318107 6480464 Dicarbethoxydihydrocollidine results in decreased expression of SIRT3 mRNA CTD PMID:18098314 4-hydroxynon-2-enal multiple interactions ISO RGD:1318106 6480464 4-hydroxy-2-nonenal binds to and results in decreased activity of SIRT3 protein CTD PMID:21449565 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:31981641 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide decreases activity ISO RGD:1318106 6480464 6-chloro-2 more ... CTD PMID:26518726 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of SIRT3 mRNA CTD PMID:30047161 8-Br-cAMP increases expression ISO RGD:1318107 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SIRT3 mRNA CTD PMID:23166782 ADP decreases abundance ISO RGD:1318107 6480464 SIRT3 protein results in decreased abundance of Adenosine Diphosphate CTD PMID:23166782 aldehydo-D-glucose multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [INS1 protein results in increased uptake of Glucose]] CTD PMID:25979314 aldehydo-D-glucose multiple interactions ISO RGD:1318106 6480464 SIRT3 protein inhibits the reaction [Glucose results in increased acetylation of FOXO1 protein] more ... CTD PMID:23494737 aldehydo-D-glucose increases expression ISO RGD:1318106 6480464 Glucose deficiency results in increased expression of SIRT3 protein CTD PMID:23494737 alpha-mangostin increases expression ISO RGD:1318106 6480464 mangostin results in increased expression of SIRT3 protein CTD PMID:30502394 alpha-mangostin multiple interactions ISO RGD:1318106 6480464 SIRT3 protein affects the reaction [mangostin results in decreased expression of ACTA2 protein], SIRT3 protein affects the reaction [mangostin results in decreased secretion of HMGB1 protein] CTD PMID:30502394 alpha-mangostin multiple interactions ISO RGD:1318107 6480464 [mangostin co-treated with Carbon Tetrachloride] results in increased expression of and results in increased secretion of SIRT3 protein CTD PMID:30502394 amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of SIRT3 mRNA CTD PMID:30047161 antimycin A multiple interactions ISO RGD:1318106 6480464 Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SIRT3 mRNA] CTD PMID:35430258 antimycin A increases expression ISO RGD:1318106 6480464 Antimycin A results in increased expression of SIRT3 mRNA CTD PMID:35430258 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of SIRT3 protein CTD PMID:30385301 arsenous acid multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Metformin] results in increased expression of SIRT3 protein CTD PMID:30385301 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of SIRT3 mRNA CTD PMID:29223816 ATP multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [Metformin results in decreased abundance of Adenosine Triphosphate] CTD PMID:23166782 atrazine affects expression ISO RGD:1318106 6480464 Atrazine affects the expression of SIRT3 mRNA CTD PMID:27114639 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of SIRT3 mRNA CTD PMID:27114639 benzo[a]pyrene decreases expression ISO RGD:1318107 6480464 Benzo(a)pyrene results in decreased expression of SIRT3 mRNA CTD PMID:19770486 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of SIRT3 mRNA, Benzo(a)pyrene results in increased expression of SIRT3 protein CTD PMID:35940284 benzo[a]pyrene multiple interactions EXP 6480464 ramelteon inhibits the reaction [Benzo(a)pyrene results in increased expression of SIRT3 mRNA], ramelteon inhibits the reaction [Benzo(a)pyrene results in increased expression of SIRT3 protein] CTD PMID:35940284 benzo[a]pyrene increases methylation ISO RGD:1318106 6480464 Benzo(a)pyrene results in increased methylation of SIRT3 3' UTR CTD PMID:27901495 benzo[a]pyrene increases expression ISO RGD:1318107 6480464 Benzo(a)pyrene results in increased expression of SIRT3 mRNA CTD PMID:22228805 benzo[a]pyrene diol epoxide I increases expression ISO RGD:1318106 6480464 7 more ... CTD PMID:35940284 berberine increases expression ISO RGD:1318106 6480464 Berberine results in increased expression of SIRT3 mRNA CTD PMID:27311644 berberine multiple interactions ISO RGD:1318106 6480464 [Berberine co-treated with Niacinamide] results in decreased expression of SIRT3 protein CTD PMID:26712469 berberine decreases expression ISO RGD:1318106 6480464 Berberine results in decreased expression of SIRT3 mRNA, Berberine results in decreased expression of SIRT3 protein CTD PMID:26712469 bisphenol A decreases expression ISO RGD:1318107 6480464 bisphenol A results in decreased expression of SIRT3 mRNA CTD PMID:25575267 , PMID:31016965 bisphenol A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SIRT3 protein] CTD PMID:30641872 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SIRT3 mRNA, bisphenol A results in decreased expression of SIRT3 protein CTD PMID:30641872 more ... bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of SIRT3 gene CTD PMID:28505145 bisphenol A increases methylation ISO RGD:1318107 6480464 bisphenol A results in increased methylation of SIRT3 promoter CTD PMID:27312807 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SIRT3 mRNA CTD PMID:25181051 Butylbenzyl phthalate decreases expression ISO RGD:1318106 6480464 butylbenzyl phthalate results in decreased expression of SIRT3 mRNA, butylbenzyl phthalate results in decreased expression of SIRT3 protein CTD PMID:26520405 Butylbenzyl phthalate decreases expression ISO RGD:1318107 6480464 butylbenzyl phthalate results in decreased expression of SIRT3 mRNA, butylbenzyl phthalate results in decreased expression of SIRT3 protein CTD PMID:27923775 , PMID:34520170 caffeine multiple interactions ISO RGD:1318106 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2 more ... CTD PMID:30555576 carbon nanotube decreases expression ISO RGD:1318107 6480464 Nanotubes, Carbon analog results in decreased expression of SIRT3 mRNA CTD PMID:25554681 CGS-21680 multiple interactions ISO RGD:1318106 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2, 2'-azobis(2-amidinopropane) results in decreased expression of SIRT3 protein]] CTD PMID:30555576 chloroquine increases stability ISO RGD:1318106 6480464 Chloroquine results in increased stability of SIRT3 mRNA CTD PMID:35302183 chloroquine multiple interactions ISO RGD:1318106 6480464 Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 mRNA], Chloroquine inhibits the reaction [hydroquinone results in decreased expression of SIRT3 protein] CTD PMID:35302183 choline multiple interactions ISO RGD:1318107 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SIRT3 gene CTD PMID:20938992 chromium(6+) affects response to substance ISO RGD:1318106 6480464 SIRT3 affects the susceptibility to chromium hexavalent ion CTD PMID:30715550 chromium(6+) multiple interactions ISO RGD:1318106 6480464 chromium hexavalent ion promotes the reaction [NFE2L2 protein binds to SIRT3 promoter] CTD PMID:30715550 chromium(6+) increases expression ISO RGD:1318106 6480464 chromium hexavalent ion results in increased expression of SIRT3 mRNA, chromium hexavalent ion results in increased expression of SIRT3 protein CTD PMID:30715550 cisplatin decreases response to substance ISO RGD:1318106 6480464 SIRT3 protein results in decreased susceptibility to Cisplatin CTD PMID:21472714 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of SIRT3 mRNA, Cisplatin results in decreased expression of SIRT3 protein CTD PMID:36800006 cisplatin multiple interactions ISO RGD:1318106 6480464 Cisplatin results in decreased expression of and results in decreased activity of SIRT3 protein more ... CTD PMID:27722009 cisplatin affects response to substance ISO RGD:1318106 6480464 SIRT3 protein affects the susceptibility to Cisplatin CTD PMID:27722009 cisplatin multiple interactions ISO RGD:1318107 6480464 SIRT3 promotes the reaction [Metformin inhibits the reaction [Cisplatin affects the localization of SLC2A4 protein]] more ... CTD PMID:36800006 cisplatin multiple interactions EXP 6480464 Cisplatin results in decreased expression of and results in decreased activity of SIRT3 protein more ... CTD PMID:28698153 , PMID:36800006 copper(II) sulfate decreases expression ISO RGD:1318106 6480464 Copper Sulfate results in decreased expression of SIRT3 mRNA CTD PMID:19549813 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [[Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of SIRT3 mRNA] more ... CTD PMID:28698153 , PMID:28951138 curcumin multiple interactions ISO RGD:1318106 6480464 Curcumin inhibits the reaction [[GYY 4137 results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]] CTD PMID:26422756 D-glucose multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [INS1 protein results in increased uptake of Glucose]] CTD PMID:25979314 D-glucose increases expression ISO RGD:1318106 6480464 Glucose deficiency results in increased expression of SIRT3 protein CTD PMID:23494737 D-glucose multiple interactions ISO RGD:1318106 6480464 SIRT3 protein inhibits the reaction [Glucose results in increased acetylation of FOXO1 protein] more ... CTD PMID:23494737 deguelin decreases expression ISO RGD:1318106 6480464 deguelin results in decreased expression of SIRT3 mRNA CTD PMID:33512557 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of SIRT3 protein CTD PMID:30385301 diarsenic trioxide multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Metformin] results in increased expression of SIRT3 protein CTD PMID:30385301 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of SIRT3 mRNA CTD PMID:29223816 diazinon increases methylation ISO RGD:1318106 6480464 Diazinon results in increased methylation of SIRT3 gene CTD PMID:22964155 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of SIRT3 mRNA CTD PMID:21266533 diethylstilbestrol decreases expression ISO RGD:1318107 6480464 Diethylstilbestrol results in decreased expression of SIRT3 mRNA CTD PMID:25575267 diisononyl phthalate decreases expression ISO RGD:1318106 6480464 diisononyl phthalate results in decreased expression of SIRT3 mRNA, diisononyl phthalate results in decreased expression of SIRT3 protein CTD PMID:31423773 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of SIRT3 protein CTD PMID:26678157 doxorubicin decreases expression ISO RGD:1318106 6480464 Doxorubicin results in decreased expression of SIRT3 mRNA CTD PMID:29803840 estriol decreases expression ISO RGD:1318107 6480464 Estriol results in decreased expression of SIRT3 mRNA CTD PMID:25575267 ethanol increases metabolic processing ISO RGD:1318107 6480464 Ethanol results in increased metabolism of SIRT3 protein CTD PMID:21449565 ethanol multiple interactions EXP 6480464 1 more ... CTD PMID:18793633 , PMID:35872049 ethanol increases expression EXP 6480464 Ethanol results in increased expression of SIRT3 mRNA CTD PMID:18793633 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of SIRT3 mRNA CTD PMID:24136188 folic acid multiple interactions ISO RGD:1318107 6480464 [1 more ... CTD PMID:20938992 , PMID:22206623 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of SIRT3 mRNA CTD PMID:33387578 glucose multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [INS1 protein results in increased uptake of Glucose]] CTD PMID:25979314 glucose increases expression ISO RGD:1318106 6480464 Glucose deficiency results in increased expression of SIRT3 protein CTD PMID:23494737 glucose multiple interactions ISO RGD:1318106 6480464 SIRT3 protein inhibits the reaction [Glucose results in increased acetylation of FOXO1 protein] more ... CTD PMID:23494737 hexadecanoic acid decreases expression ISO RGD:1318106 6480464 Palmitic Acid results in decreased expression of SIRT3 protein CTD PMID:30958623 Honokiol multiple interactions EXP 6480464 honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of SIRT3 protein] more ... CTD PMID:33522075 , PMID:34752757 hydrogen peroxide multiple interactions ISO RGD:1318106 6480464 [GYY 4137 results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA] more ... CTD PMID:26422756 hydrogen peroxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA] more ... CTD PMID:30104959 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of SIRT3 mRNA, Hydrogen Peroxide results in decreased expression of SIRT3 protein CTD PMID:30104959 hydrogen peroxide decreases expression ISO RGD:1318106 6480464 Hydrogen Peroxide results in decreased expression of SIRT3 mRNA, Hydrogen Peroxide results in decreased expression of SIRT3 protein CTD PMID:26422756 hydrogen sulfide multiple interactions EXP 6480464 [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein], NFE2L2 protein affects the reaction [[sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein]] CTD PMID:32064027 hydrogen sulfide multiple interactions ISO RGD:1318106 6480464 [GYY 4137 results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA] more ... CTD PMID:26422756 hydroquinone multiple interactions ISO RGD:1318106 6480464 [[NOX4 protein results in decreased expression of ELAVL2 protein] which promotes the reaction SIDT2 protein] promotes the reaction [hydroquinone results in decreased degradation of SIRT3 protein] more ... CTD PMID:35302183 hydroquinone decreases expression ISO RGD:1318106 6480464 hydroquinone results in decreased expression of SIRT3 mRNA, hydroquinone results in decreased expression of SIRT3 protein CTD PMID:35302183 hydroquinone increases degradation ISO RGD:1318106 6480464 hydroquinone results in increased degradation of SIRT3 mRNA CTD PMID:35302183 icariin multiple interactions EXP 6480464 Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression of SIRT3 protein]], icariin inhibits the reaction [Rotenone results in decreased expression of SIRT3 protein] CTD PMID:31251943 L-methionine multiple interactions ISO RGD:1318107 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SIRT3 gene CTD PMID:20938992 lead diacetate multiple interactions ISO RGD:1318107 6480464 PPARGC1A protein affects the reaction [lead acetate results in increased expression of SIRT3 protein] CTD PMID:27236077 lead diacetate increases expression ISO RGD:1318107 6480464 lead acetate results in increased expression of SIRT3 protein CTD PMID:27236077 linalool decreases expression ISO RGD:1318106 6480464 linalool results in decreased expression of SIRT3 mRNA, linalool results in decreased expression of SIRT3 protein CTD PMID:28567457 linalool multiple interactions ISO RGD:1318106 6480464 linalool inhibits the reaction [SOD2 protein binds to SIRT3 protein] CTD PMID:28567457 lipoic acid multiple interactions EXP 6480464 [Thioctic Acid results in increased expression of [SIRT1 protein co-treated with SIRT3 protein]] which results in decreased acetylation of FOXO3 protein more ... CTD PMID:22327056 lipoic acid increases expression EXP 6480464 Thioctic Acid results in increased expression of SIRT3 protein CTD PMID:22327056 lipopolysaccharide multiple interactions EXP 6480464 [Lipopolysaccharides co-treated with Tobacco Smoke Pollution] results in decreased expression of SIRT3 mRNA more ... CTD PMID:28951138 mancozeb decreases activity ISO RGD:1318106 6480464 mancozeb results in decreased activity of SIRT3 protein CTD PMID:21251949 maneb decreases activity ISO RGD:1318106 6480464 Maneb results in decreased activity of SIRT3 protein CTD PMID:21251949 metformin decreases expression ISO RGD:1318107 6480464 Metformin results in decreased expression of SIRT3 mRNA, Metformin results in decreased expression of SIRT3 protein CTD PMID:23166782 , PMID:24687991 metformin multiple interactions ISO RGD:1318106 6480464 Metformin results in increased expression of and results in increased activity of SIRT3 protein CTD PMID:33147367 metformin increases expression EXP 6480464 Metformin results in increased expression of SIRT3 protein CTD PMID:30385301 metformin multiple interactions EXP 6480464 [Arsenic Trioxide co-treated with Metformin] results in increased expression of SIRT3 protein more ... CTD PMID:30385301 , PMID:36800006 metformin decreases response to substance ISO RGD:1318107 6480464 SIRT3 protein results in decreased susceptibility to Metformin CTD PMID:23166782 metformin multiple interactions ISO RGD:1318107 6480464 Metformin inhibits the reaction [GCG protein results in increased expression of SIRT3 mRNA] more ... CTD PMID:23166782 , PMID:36800006 methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of SIRT3 mRNA CTD PMID:30047161 methotrexate affects expression ISO RGD:1318107 6480464 Methotrexate affects the expression of SIRT3 mRNA CTD PMID:18502557 metiram decreases activity ISO RGD:1318106 6480464 polymarcine results in decreased activity of SIRT3 protein CTD PMID:21251949 mono(2-ethylhexyl) phthalate increases expression ISO RGD:1318107 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of SIRT3 mRNA CTD PMID:25543134 , PMID:32522588 mono(2-ethylhexyl) phthalate decreases expression ISO RGD:1318107 6480464 mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT3 mRNA, mono-(2-ethylhexyl)phthalate results in decreased expression of SIRT3 protein CTD PMID:31016965 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SIRT3 protein] more ... CTD PMID:30104959 , PMID:30641872 N-acetyl-L-cysteine multiple interactions ISO RGD:1318106 6480464 Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SIRT3 mRNA] CTD PMID:35430258 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of SIRT3 mRNA CTD PMID:28801915 nebivolol multiple interactions ISO RGD:1318107 6480464 3-(2-ethylphenoxy)-1-(1 more ... CTD PMID:23886954 nebivolol increases expression ISO RGD:1318107 6480464 Nebivolol results in increased expression of SIRT3 protein CTD PMID:23886954 nicotinamide multiple interactions ISO RGD:1318106 6480464 [Berberine co-treated with Niacinamide] results in decreased expression of SIRT3 protein CTD PMID:26712469 paracetamol affects expression ISO RGD:1318107 6480464 Acetaminophen affects the expression of SIRT3 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of SIRT3 mRNA CTD PMID:33387578 paraquat multiple interactions EXP 6480464 [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein] more ... CTD PMID:32064027 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of SIRT3 protein CTD PMID:32064027 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:1318106 6480464 perfluorooctane sulfonic acid results in decreased expression of SIRT3 mRNA, perfluorooctane sulfonic acid results in decreased expression of SIRT3 protein CTD PMID:31508952 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1318107 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SIRT3 mRNA CTD PMID:36331819 perfluorooctane-1-sulfonic acid increases expression ISO RGD:1318107 6480464 perfluorooctane sulfonic acid results in increased expression of SIRT3 mRNA CTD PMID:31016965 perfluorooctanoic acid increases expression ISO RGD:1318107 6480464 perfluorooctanoic acid results in increased expression of SIRT3 mRNA CTD PMID:31016965 pregnenolone 16alpha-carbonitrile decreases expression EXP 6480464 Pregnenolone Carbonitrile results in decreased expression of SIRT3 mRNA CTD PMID:30047161 propiconazole decreases expression ISO RGD:1318107 6480464 propiconazole results in decreased expression of SIRT3 mRNA CTD PMID:21278054 propionic acid increases expression ISO RGD:1318106 6480464 propionic acid results in increased expression of SIRT3 mRNA, propionic acid results in increased expression of SIRT3 protein CTD PMID:31526819 reactive oxygen species multiple interactions ISO RGD:1318106 6480464 SIRT3 protein inhibits the reaction [Particulate Matter results in increased abundance of Reactive Oxygen Species] CTD PMID:27125970 resveratrol decreases expression ISO RGD:1318106 6480464 resveratrol results in decreased expression of SIRT3 mRNA CTD PMID:21980390 resveratrol decreases expression ISO RGD:1318107 6480464 resveratrol results in decreased expression of SIRT3 mRNA CTD PMID:23525482 resveratrol increases activity ISO RGD:1318106 6480464 resveratrol results in increased activity of SIRT3 protein CTD PMID:24178296 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [Dietary Fats results in decreased expression of SIRT3 protein], resveratrol inhibits the reaction [Ethanol results in increased expression of SIRT3 mRNA] CTD PMID:18793633 , PMID:25686565 resveratrol increases expression ISO RGD:1318106 6480464 resveratrol results in increased expression of SIRT3 mRNA CTD PMID:25522270 resveratrol multiple interactions ISO RGD:1318106 6480464 PPARGC1A mutant form inhibits the reaction [resveratrol results in increased expression of SIRT3 mRNA] more ... CTD PMID:22585829 , PMID:25522270 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of SIRT3 protein CTD PMID:31251943 rotenone multiple interactions EXP 6480464 Histone Deacetylase Inhibitors inhibits the reaction [icariin inhibits the reaction [Rotenone results in decreased expression of SIRT3 protein]], icariin inhibits the reaction [Rotenone results in decreased expression of SIRT3 protein] CTD PMID:31251943 rotenone multiple interactions ISO RGD:1318106 6480464 SIRT3 protein inhibits the reaction [Rotenone results in increased expression of SNCA protein] CTD PMID:27053302 sodium arsenite multiple interactions ISO RGD:1318107 6480464 SIRT3 protein inhibits the reaction [sodium arsenite inhibits the reaction [FOXO3 protein binds to PPARGC1A promoter]] more ... CTD PMID:25979314 sodium arsenite decreases expression ISO RGD:1318107 6480464 sodium arsenite results in decreased expression of SIRT3 protein CTD PMID:25979314 sodium fluoride multiple interactions ISO RGD:1318106 6480464 [Sodium Fluoride results in increased abundance of Fluorides] which results in decreased expression of SIRT3 protein more ... CTD PMID:34780879 sodium fluoride multiple interactions ISO RGD:1318107 6480464 [Sodium Fluoride results in increased abundance of Fluorides] which results in decreased expression of SIRT3 protein CTD PMID:34780879 sodium sulfide (anhydrous) multiple interactions EXP 6480464 [sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein], NFE2L2 protein affects the reaction [[sodium sulfide results in increased abundance of Hydrogen Sulfide] inhibits the reaction [Paraquat results in decreased expression of SIRT3 protein]] CTD PMID:32064027 Soman decreases expression EXP 6480464 Soman results in decreased expression of SIRT3 mRNA CTD PMID:19281266 stavudine increases expression ISO RGD:1318106 6480464 Stavudine results in increased expression of SIRT3 protein CTD PMID:27041070 sulfadimethoxine decreases expression EXP 6480464 Sulfadimethoxine results in decreased expression of SIRT3 mRNA CTD PMID:30047161 tenofovir disoproxil fumarate increases expression ISO RGD:1318106 6480464 Tenofovir results in increased expression of SIRT3 protein CTD PMID:27041070 tert-butyl hydroperoxide multiple interactions ISO RGD:1318106 6480464 SIRT3 mutant form inhibits the reaction [resveratrol inhibits the reaction [tert-Butylhydroperoxide results in decreased activity of and results in increased acetylation of SOD2 protein]], SIRT3 mutant form inhibits the reaction [resveratrol inhibits the reaction [tert-Butylhydroperoxide results in decreased activity of IDH2 protein]] CTD PMID:25522270 tetrachloromethane decreases expression ISO RGD:1318107 6480464 Carbon Tetrachloride results in decreased expression of SIRT3 mRNA, Carbon Tetrachloride results in decreased expression of SIRT3 protein CTD PMID:27339419 more ... tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of SIRT3 mRNA CTD PMID:31150632 tetrachloromethane multiple interactions ISO RGD:1318107 6480464 [mangostin co-treated with Carbon Tetrachloride] results in increased expression of and results in increased secretion of SIRT3 protein more ... CTD PMID:30368983 , PMID:30502394 tetrachloromethane decreases response to substance ISO RGD:1318107 6480464 SIRT3 protein results in decreased susceptibility to Carbon Tetrachloride CTD PMID:30368983 tetrachloromethane multiple interactions EXP 6480464 1 more ... CTD PMID:31150632 , PMID:35872049 thapsigargin decreases expression ISO RGD:1318106 6480464 Thapsigargin results in decreased expression of SIRT3 mRNA CTD PMID:22378314 thioacetamide multiple interactions EXP 6480464 honokiol inhibits the reaction [Thioacetamide results in decreased expression of and results in decreased activity of SIRT3 protein], Thioacetamide results in decreased expression of and results in decreased activity of SIRT3 protein CTD PMID:33522075 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of SIRT3 mRNA CTD PMID:34492290 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of SIRT3 mRNA CTD PMID:33387578 trilobatin multiple interactions EXP 6480464 trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA], trilobatin inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 protein] CTD PMID:30104959 triptonide increases expression ISO RGD:1318107 6480464 triptonide results in increased expression of SIRT3 mRNA CTD PMID:33045310 tris(2-chloroethyl) phosphate decreases expression ISO RGD:1318106 6480464 tris(chloroethyl)phosphate results in decreased expression of SIRT3 mRNA, tris(chloroethyl)phosphate results in decreased expression of SIRT3 protein CTD PMID:30090360 tunicamycin decreases expression ISO RGD:1318106 6480464 Tunicamycin results in decreased expression of SIRT3 mRNA CTD PMID:22378314 urethane decreases expression ISO RGD:1318106 6480464 Urethane results in decreased expression of SIRT3 mRNA CTD PMID:28818685 valdecoxib decreases expression EXP 6480464 valdecoxib results in decreased expression of SIRT3 mRNA CTD PMID:24136188 valproic acid decreases methylation ISO RGD:1318106 6480464 Valproic Acid results in decreased methylation of SIRT3 gene CTD PMID:29154799 vancomycin increases expression ISO RGD:1318107 6480464 Vancomycin results in increased expression of SIRT3 mRNA CTD PMID:18930951 zidovudine increases expression ISO RGD:1318106 6480464 Zidovudine results in increased expression of SIRT3 protein CTD PMID:27041070