Lcp1 (lymphocyte cytosolic protein 1)

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Gene: Lcp1 (lymphocyte cytosolic protein 1) Rattus norvegicus

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Symbol:

Lcp1

Name:

lymphocyte cytosolic protein 1

RGD ID:

1308288

Description:

Predicted to enable GTPase binding activity; actin filament binding activity; and integrin binding activity. Involved in animal organ regeneration. Predicted to be located in several cellular components, including actin cytoskeleton; focal adhesion; and ruffle. Predicted to be active in actin filament; actin filament bundle; and cytoplasm. Human ortholog(s) of this gene implicated in nicotine dependence. Orthologous to human LCP1 (lymphocyte cytosolic protein 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC306071; plastin-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LCP1 (lymphocyte cytosolic protein 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Lcp1 (lymphocyte cytosolic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lcp1 (lymphocyte cytosolic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LCP1 (lymphocyte cytosolic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LCP1 (lymphocyte cytosolic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lcp1 (lymphocyte cytosolic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LCP1 (lymphocyte cytosolic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LCP1 (lymphocyte cytosolic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lcp1 (lymphocyte cytosolic protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	PLS3 (plastin 3)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	LCP1 (lymphocyte cytosolic protein 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Lcp1 (lymphocyte cytosolic protein 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lcp1 (lymphocyte cytosolic protein 1 (L-plastin))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Fim	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SAC6	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	plst-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	lcp1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Candidate Gene For:

Bmd62

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	56,846,375 - 56,954,090 (+)	NCBI		GRCr8
mRatBN7.2	15	50,443,300 - 50,544,682 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	50,488,149 - 50,544,680 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	54,630,232 - 54,686,870 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	55,748,540 - 55,805,188 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	52,580,535 - 52,637,056 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	57,170,566 - 57,277,811 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	57,221,292 - 57,277,811 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	60,888,052 - 60,988,851 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	56,034,457 - 56,091,880 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	56,050,236 - 56,107,660 (+)	NCBI
Celera	15	50,120,119 - 50,176,635 (+)	NCBI		Celera
Cytogenetic Map	15	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acute Otitis Media (ISO)

Experimental Liver Cirrhosis (ISO)

hereditary breast ovarian cancer syndrome (ISO)

nicotine dependence (ISO)

Tobacco Use Disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-trinitrobenzenesulfonic acid (ISO)

2-palmitoylglycerol (ISO)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

aniline (EXP)

antirheumatic drug (ISO)

Aroclor 1254 (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

bathocuproine disulfonic acid (ISO)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bleomycin A2 (ISO)

buspirone (EXP)

cadmium dichloride (EXP,ISO)

calyculin a (ISO)

cannabidiol (ISO)

cantharidin (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (EXP)

clofibrate (ISO)

Cuprizon (EXP)

curcumin (ISO)

cyclosporin A (ISO)

deoxynivalenol (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dimethylarsinic acid (ISO)

dimethylarsinous acid (ISO)

diuron (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

enzalutamide (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

gentamycin (EXP)

hydroxyflutamide (ISO)

indoles (EXP)

ionomycin (ISO)

KT 5926 (ISO)

lead diacetate (ISO)

lidocaine (EXP)

lithium chloride (ISO)

methylarsonic acid (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

nicotine (ISO)

nimesulide (EXP)

oxycodone (EXP)

paracetamol (EXP,ISO)

phenylmercury acetate (ISO)

phorbol 13-acetate 12-myristate (ISO)

pirinixic acid (ISO)

progesterone (ISO)

pyrrolidine dithiocarbamate (ISO)

rotenone (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sotorasib (ISO)

tanespimycin (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

trametinib (ISO)

trichloroethene (EXP)

triclosan (ISO)

trimellitic anhydride (ISO)

triphenyl phosphate (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament bundle assembly (IBA,ISO)

actin filament network formation (IBA)

animal organ regeneration (IEP)

cell migration (ISO)

extracellular matrix disassembly (ISO)

positive regulation of podosome assembly (ISO)

protein kinase A signaling (ISO)

regulation of intracellular protein transport (ISO)

T cell activation involved in immune response (ISO)

wound healing, spreading of cells (ISO)

Cellular Component

actin cytoskeleton (ISO)

actin filament (IBA,ISO)

actin filament bundle (IBA,ISO)

cytoplasm (IBA,ISO)

cytosol (ISO)

filopodium (ISO)

focal adhesion (ISO)

glial cell projection (ISO)

perinuclear region of cytoplasm (ISO)

phagocytic cup (ISO)

plasma membrane (ISO)

podosome (ISO)

ruffle (ISO)

stress fiber (ISO)

Molecular Function

actin filament binding (IBA,ISO)

calcium ion binding (IEA)

GTPase binding (ISO)

identical protein binding (IEA)

integrin binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Comprehensive gene review and curation	RGD comprehensive gene curation
8.	Proteomic analysis of differential protein expression in early process of pancreatic regeneration in pancreatectomized rats.	Yang M, etal., Acta Pharmacol Sin. 2006 May;27(5):568-78.
9.	Substance dependence low-density whole genome association study in two distinct American populations.	Yu Y, etal., Hum Genet. 2008 Jun;123(5):495-506. doi: 10.1007/s00439-008-0501-0. Epub 2008 Apr 26.

Additional References at PubMed

PMID:2111166	PMID:7655078	PMID:11591653	PMID:12477932	PMID:14756805	PMID:16502470	PMID:16636079	PMID:17294403	PMID:19056867	PMID:20183869	PMID:20458337	PMID:21922118
PMID:22664934	PMID:23533145	PMID:24236012	PMID:24337748	PMID:33450132	PMID:36574182

Genomics

Comparative Map Data

Lcp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	56,846,375 - 56,954,090 (+)	NCBI		GRCr8
mRatBN7.2	15	50,443,300 - 50,544,682 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	50,488,149 - 50,544,680 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	54,630,232 - 54,686,870 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	55,748,540 - 55,805,188 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	52,580,535 - 52,637,056 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	57,170,566 - 57,277,811 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	57,221,292 - 57,277,811 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	60,888,052 - 60,988,851 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	56,034,457 - 56,091,880 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	56,050,236 - 56,107,660 (+)	NCBI
Celera	15	50,120,119 - 50,176,635 (+)	NCBI		Celera
Cytogenetic Map	15	q11	NCBI

LCP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	46,125,923 - 46,182,177 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	46,125,920 - 46,211,871 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	46,700,058 - 46,756,312 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	45,598,060 - 45,654,395 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	13	45,598,059 - 45,654,395	NCBI
Celera	13	27,755,067 - 27,811,461 (-)	NCBI		Celera
Cytogenetic Map	13	q14.13	NCBI
HuRef	13	27,497,877 - 27,554,218 (-)	NCBI		HuRef
CHM1_1	13	46,669,191 - 46,725,269 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	45,347,305 - 45,403,192 (-)	NCBI		T2T-CHM13v2.0

Lcp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	75,368,570 - 75,468,282 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	75,368,541 - 75,468,282 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	75,131,105 - 75,230,842 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	75,131,101 - 75,230,842 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	75,536,232 - 75,630,615 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	73,870,580 - 73,964,963 (+)	NCBI		MGSCv36	mm8
Celera	14	72,636,371 - 72,732,832 (+)	NCBI		Celera
Cytogenetic Map	14	D3	NCBI
cM Map	14	39.63	NCBI

Lcp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955518	3,814,840 - 3,891,299 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955518	3,815,181 - 3,863,440 (-)	NCBI	ChiLan1.0	ChiLan1.0

LCP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	45,180,206 - 45,266,387 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	36,234,410 - 36,320,594 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	26,820,846 - 26,906,916 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

LCP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	4,955,453 - 5,059,654 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	4,992,347 - 5,059,636 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	4,965,424 - 5,047,265 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	5,070,372 - 5,176,432 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	5,123,064 - 5,175,065 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	4,852,728 - 4,958,773 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	4,916,029 - 5,022,003 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	4,921,102 - 5,027,186 (+)	NCBI		UU_Cfam_GSD_1.0

Lcp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	156,224,062 - 156,314,492 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936857	646,118 - 698,035 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936857	646,363 - 726,338 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LCP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	21,126,539 - 21,223,550 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	21,126,504 - 21,223,543 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	21,535,029 - 21,685,279 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LCP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	24,182,086 - 24,238,746 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	24,182,076 - 24,238,651 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666057	19,776,506 - 19,834,713 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lcp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624748	8,779,395 - 8,835,500 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624748	8,740,563 - 8,833,091 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Lcp1
550 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	594
Count of miRNA genes:	266
Interacting mature miRNAs:	329
Transcripts:	ENSRNOT00000014502
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631273	Lecl2	Lens clarity QTL 2		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	15	10596089	55596089	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	40631268	98288169	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	17362897	73690657	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	22117933	67117933	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat
2293686	Bmd36	Bone mineral density QTL 36	7.4	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	15	33611058	71477291	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	34054139	79054139	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	12496141	65205939	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
2293691	Bmd37	Bone mineral density QTL 37	6.6	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	15	33611058	71477291	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	11111142	56111142	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat

Markers in Region

D15Mgh2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	50,531,797 - 50,531,936 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	57,264,937 - 57,265,073	NCBI	Rnor6.0
Rnor_5.0	15	60,975,977 - 60,976,113	UniSTS	Rnor5.0
RGSC_v3.4	15	56,079,087 - 56,079,224	RGD	RGSC3.4
RGSC_v3.4	15	56,079,088 - 56,079,224	UniSTS	RGSC3.4
RGSC_v3.1	15	56,094,867 - 56,095,004	RGD
Celera	15	50,163,764 - 50,163,900	UniSTS
Cytogenetic Map	15	q11	UniSTS

RH128715

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	50,544,425 - 50,544,605 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	57,277,555 - 57,277,734	NCBI	Rnor6.0
Rnor_5.0	15	60,988,595 - 60,988,774	UniSTS	Rnor5.0
RGSC_v3.4	15	56,091,626 - 56,091,805	UniSTS	RGSC3.4
Celera	15	50,176,381 - 50,176,560	UniSTS
Cytogenetic Map	15	q11	UniSTS

BI273777

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	50,543,552 - 50,543,665 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	57,276,682 - 57,276,794	NCBI	Rnor6.0
Rnor_5.0	15	60,987,722 - 60,987,834	UniSTS	Rnor5.0
RGSC_v3.4	15	56,090,753 - 56,090,865	UniSTS	RGSC3.4
Celera	15	50,175,508 - 50,175,620	UniSTS
Cytogenetic Map	15	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

appendage

High

Medium

173

110

143

111

116

Low

107

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252322	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599707	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274316	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC110315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014502 ⟹ ENSRNOP00000014502

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	50,488,149 - 50,544,680 (+)	Ensembl
Rnor_6.0 Ensembl	15	57,221,292 - 57,277,809 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000082191 ⟹ ENSRNOP00000071263

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	50,508,815 - 50,544,680 (+)	Ensembl
Rnor_6.0 Ensembl	15	57,241,968 - 57,277,811 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094863 ⟹ ENSRNOP00000092952

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	50,488,149 - 50,544,680 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105314 ⟹ ENSRNOP00000083584

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	50,508,815 - 50,544,680 (+)	Ensembl

RefSeq Acc Id:

NM_001012044 ⟹ NP_001012044

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	56,897,571 - 56,954,088 (+)	NCBI
mRatBN7.2	15	50,488,149 - 50,544,680 (+)	NCBI
Rnor_6.0	15	57,221,292 - 57,277,809 (+)	NCBI
Rnor_5.0	15	60,888,052 - 60,988,851 (+)	NCBI
RGSC_v3.4	15	56,034,457 - 56,091,880 (+)	RGD
Celera	15	50,120,119 - 50,176,635 (+)	RGD

Sequence:

show sequence

CCGAGGACAGTGTCTCTACAAGGTCTGTCACCTAAAGCAGTCAAAATGGCCAGAGGATCCGTGT
CTGATGAAGAAATGATGGAGCTCAGAGAGGCTTTTGCCAAAGTCGATACTGACGGCAACGGGTA
CATCAGCTGCAATGAACTGAATGACTTGTTCAAGGCGGCCTGCCTGCCTCTGCCTGGCTACCGA
GTGAGAGAAATCACAGAGAACCTGATGGCCACAGGTGACCTGGACCAAGATGGGAAGATTAGCT
TTGATGAGTTTATCAAGGTCTTCCATGGCTTAAAAAGCACCGAGGTTGCCAAAACCTTCCGAAA
AGCTATCAACAAGAAGGAAGGGATCTGTGCGATCGGTGGCACCTCTGAGCAGTCCAGCGTGGGT
ACCCAGCATTCCTACTCAGAGGAAGAAAAGTATGCCTTTGTCAACTGGATAAACAAAGCCCTGG
AGAATGACCCTGACTGCCGGCACGTCATCCCCATGAACCCGAACACCGATGATCTCTTCAATGC
TGTCGGGGATGGCATAGTTCTTTGTAAAATGGTCAACCTGTCTGTGCCAGACACAATTGATGAA
AGAACAATCAACAAGAAGAAGCTCACACCGTTCACCATTCAGGAAAACTTGAACTTAGCTCTGA
ACTCTGCCTCGGCCATCGGATGCCATGTAGTTAATATAGGGGCTGAGGACCTGAAGGAGGGGAA
GCCATATCTGGTCCTGGGACTTTTGTGGCAAGTTATCAAGATTGGGTTGTTTGCTGACATTGAA
CTCAGCAGAAATGAAGCTCTGATTGCTCTTTTGAGAGAAGGAGAGAGCCTAGAGGATTTGATGA
AGTTGTCTCCTGAAGAACTCCTGTTGCGGTGGGCGAACTACCACCTAGAAAATGCAGGCTGCAC
CAAAATCACCAACTTCAGCACTGACATCAAGGACTCGAAAGCTTATTACCACCTGCTCGAGCAG
GTGGCTCCGAGAGGAGATGAAGAAGGGATCCCGGCTGTAGTGATTGACATGTCAGGACTGAGGG
AGAAGGATGACATCCAGAGAGCAGAGTGTATGTTGCAGCAGGCAGAGAGGCTGGGCTGCCGGCA
GTTTGTCACAGCCACTGATGTTGTCCGAGGGAACCCCAAGTTGAACCTGGCCTTCATTGCCAAC
CTCTTTAACAAATACCCTGCCTTGCACAAACCGGAGAACCAGGACATTGACTGGGGGGCTCTCG
AAGGTGAGACGAGGGAAGAGCGGACGTTCAGGAACTGGATGAACTCACTGGGAGTTAACCCTGG
AGTCAATCATTTGTACAGCGACTTATCCGACGCCCTGGTCATCTTCCAGCTCTATGAAAAGATC
AAAGTCCCTGTTGACTGGAACAGAGTAAACAGACCTCCATACCCCAAGCTGGGGGGCAACATGA
AAAAGCTCGAGAACTGTAATTATGCAGTGGATCTGGGGAAGAATCAAGCTAAATTTTCCCTAGT
TGGTATCGCAGGACAAGACCTCAATGAAGGAAACCGCACTCTGACGCTGGCATTGGTTTGGCAG
CTCATGAGAAGGTACACACTGAATATCCTGGAAGATATTGGAGGTGGTCAGAAGGTCAATGATG
ACATTATTGTCAACTGGGTGAACACGACATTGAAGGAGGCACAGAAAAGTTCGTCCATCACTAG
CTTCAAGGACCCAAAGATCAGCACCAGCCTCCCGGTTCTGGATCTCATCGATGCCATTCAGCCA
GGCTCCATAAACTATGACCTTCTGAAGACAGAAAACCTGGATGATGAAGAGAAGCTCAACAATG
CAAAGTATGCTATCTCCATGGCCAGAAAAATCGGAGCAAGAGTGTATGCCCTTCCAGAAGACCT
GGTTGAAGTGAACCCCAAAATGGTCATGACAGTGTTCGCTTGCCTCATGGGGAAAGGGATGAAG
AGGGTGTAAGTCCCACAGGAGCAAGCCAGAAAGAGACACCATCAACCCTGAGGGTCAGCATGTG
ATGCTCCCAGGATACAGAGGACCATTCAAGCCATTCCAAAGTCCTGAACCTTGGAGACATTGTC
TGAAATTCGCATATTTGTTCTGCCAAGTAGCTTCTGCTATAGTCGAGCTTCTCTTTTGTTGTCC
CCACCCCCAGGAGATCTACTCGCCTACAGATTTTTTTCTTTTATTCTTTGAAATTCTTTGGGGG
AGGGGGGAGAGTTAAAAAGAAGTTATTTCCAGATGCTCACCCCACCCCCGACACCCTTGCTTTC
ACTGATAGCCAAGGATATAGACTACATTGTTCTTAAGGGTCACCTGATCTCTTGAGCCAGTTTG
ATCTAGCTGCTTTTTGCCTTGTTCAAACTGAGGACCTGGAAGGGATCGTCAAACTTGCCTTAAA
TAAAGCCTGTCACTAGAGGCTGACACTGGATGGTCACAGCCCTTCCTTGCATCTCCTCTCAGCT
TGTCTCCCTGTGAGTTTGCTCCAATCCCCTCAGAACCATACCTGCTCTGTGGTCCCCATTTTTG
CCAGCCTTGTCTCTAGGCTACTGGAGTATCTGACAAATCAGTCAAGCTCCCAGGAGTCTCTGGG
AGACTGAAAAACTGGGGTCTCAAAGAAAGTGTAATGGAGAGTAAAACCACTAGGGGGCAGTATG
GTGGGACCACAAAGCATCTACCCTTCTGTGTATATCTCCACACCTTTAACTCCTCTTGTTAGAG
AGCTGCTTATTGTGGTGTTGACAAAATGTCTGATGACAGTTGGAAGCAATCCTGCATAACTTCA
TTTGCTTTTAGACATCGACATATTTGATTGTCACCAGGCCATATTACCAATACTCACTTTGTTG
GTACTATAAAAGCTTTTGCCTCCCTAAAGTTTCTGTAAGTGGGGGGTTGATATGTGCCAATAAT
CTATGTCCCTGCCTCACCCAAATGCTTGCACGGGCACATACGCATATGTAGCTGGATGCCAAGA
GTACCATGTTGACTAGGAACTGCCTGGAATTCAAAACAGAAAAGGGACAGCATGAATTTGAATA
GCTCCCACTAGATAAGCAATTTCCACGAAAACTTACCAAAAGCTAAAACTCCACAGAGCATTGT
GAACCAAAGGTAGACTCCCTTTGCATTAGTGAAAGTCTTACTCCCACTAATGGGACTTCGTTGT
CTTCCAAAGCAGTGGAAATGCAGGATCTCAACTTCATCCCCTGACAGTGGGCTCAGGAAACCAA
TAGATGGCTCTTTCCAGCTCCCAACCAGTATTCCCGCTGCATCCGAATGCAAAGTGTTTGGCTG
TGACTTTAGTCTGAACATCATGTAGCCTCAGATGATGTTTGCCCATCTGCCTCCACGAAGTAAG
GATATTATTGTTGCCTTAATGGAAAAATGAAGATAAATCATGTTTAAAAAAATCTTTCCAAATA
AAATGTTCCCAATTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006252319 ⟹ XP_006252381

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	56,895,449 - 56,954,090 (+)	NCBI
mRatBN7.2	15	50,486,027 - 50,544,682 (+)	NCBI
Rnor_6.0	15	57,219,117 - 57,277,811 (+)	NCBI
Rnor_5.0	15	60,888,052 - 60,988,851 (+)	NCBI

Sequence:

show sequence

AGCTCAAAGTTCCTCTCCTGCTTAATCATCACAAGCAATGTTTAAACCGCGAATGAAAAAGCCT
TGCAGCCTCGCCTGGGAACGTCTGGTGTAACACCTCCTCCACAACCGCCCACCCCTGGGTGGAT
TTTCATCACTGAGAGACGCAGATGAAGAGATTACCATGGAGGAACCTGAATGGTGAAATCCAGG
ATGTGGCTCCAGGCAGTGACAGATTCCTCGGGTCTCCTGTGATCAGGCACAAGCCACGCACAGA
ATGCTCCTGTTCTCTGTTCCCCAGTTACTTCCTGCCCTGTGACCACACACCCCTGCCTGACAGG
GCTGCTCTGTAGATCTGAAGGACTGGGCTTTCTGACCACACAGCCCCGCTGCCACCGAGGACAG
TGTCTCTACAAGGTCTGTCACCTAAAGCAGTCAAAATGGCCAGAGGATCCGTGTCTGATGAAGA
AATGATGGAGCTCAGAGAGGCTTTTGCCAAAGTCGATACTGACGGCAACGGGTACATCAGCTGC
AATGAACTGAATGACTTGTTCAAGGCGGCCTGCCTGCCTCTGCCTGGCTACCGAGTGAGAGAAA
TCACAGAGAACCTGATGGCCACAGGTGACCTGGACCAAGATGGGAAGATTAGCTTTGATGAGTT
TATCAAGGTCTTCCATGGCTTAAAAAGCACCGAGGTTGCCAAAACCTTCCGAAAAGCTATCAAC
AAGAAGGAAGGGATCTGTGCGATCGGTGGCACCTCTGAGCAGTCCAGCGTGGGTACCCAGCATT
CCTACTCAGAGGAAGAAAAGTATGCCTTTGTCAACTGGATAAACAAAGCCCTGGAGAATGACCC
TGACTGCCGGCACGTCATCCCCATGAACCCGAACACCGATGATCTCTTCAATGCTGTCGGGGAT
GGCATAGTTCTTTGTAAAATGGTCAACCTGTCTGTGCCAGACACAATTGATGAAAGAACAATCA
ACAAGAAGAAGCTCACACCGTTCACCATTCAGGAAAACTTGAACTTAGCTCTGAACTCTGCCTC
GGCCATCGGATGCCATGTAGTTAATATAGGGGCTGAGGACCTGAAGGAGGGGAAGCCATATCTG
GTCCTGGGACTTTTGTGGCAAGTTATCAAGATTGGGTTGTTTGCTGACATTGAACTCAGCAGAA
ATGAAGCTCTGATTGCTCTTTTGAGAGAAGGAGAGAGCCTAGAGGATTTGATGAAGTTGTCTCC
TGAAGAACTCCTGTTGCGGTGGGCGAACTACCACCTAGAAAATGCAGGCTGCACCAAAATCACC
AACTTCAGCACTGACATCAAGGACTCGAAAGCTTATTACCACCTGCTCGAGCAGGTGGCTCCGA
GAGGAGATGAAGAAGGGATCCCGGCTGTAGTGATTGACATGTCAGGACTGAGGGAGAAGGATGA
CATCCAGAGAGCAGAGTGTATGTTGCAGCAGGCAGAGAGGCTGGGCTGCCGGCAGTTTGTCACA
GCCACTGATGTTGTCCGAGGGAACCCCAAGTTGAACCTGGCCTTCATTGCCAACCTCTTTAACA
AATACCCTGCCTTGCACAAACCGGAGAACCAGGACATTGACTGGGGGGCTCTCGAAGGTGAGAC
GAGGGAAGAGCGGACGTTCAGGAACTGGATGAACTCACTGGGAGTTAACCCTGGAGTCAATCAT
TTGTACAGCGACTTATCCGACGCCCTGGTCATCTTCCAGCTCTATGAAAAGATCAAAGTCCCTG
TTGACTGGAACAGAGTAAACAGACCTCCATACCCCAAGCTGGGGGGCAACATGAAAAAGCTCGA
GAACTGTAATTATGCAGTGGATCTGGGGAAGAATCAAGCTAAATTTTCCCTAGTTGGTATCGCA
GGACAAGACCTCAATGAAGGAAACCGCACTCTGACGCTGGCATTGGTTTGGCAGCTCATGAGAA
GGTACACACTGAATATCCTGGAAGATATTGGAGGTGGTCAGAAGGTCAATGATGACATTATTGT
CAACTGGGTGAACACGACATTGAAGGAGGCACAGAAAAGTTCGTCCATCACTAGCTTCAAGGAC
CCAAAGATCAGCACCAGCCTCCCGGTTCTGGATCTCATCGATGCCATTCAGCCAGGCTCCATAA
ACTATGACCTTCTGAAGACAGAAAACCTGGATGATGAAGAGAAGCTCAACAATGCAAAGTATGC
TATCTCCATGGCCAGAAAAATCGGAGCAAGAGTGTATGCCCTTCCAGAAGACCTGGTTGAAGTG
AACCCCAAAATGGTCATGACAGTGTTCGCTTGCCTCATGGGGAAAGGGATGAAGAGGGTGTAAG
TCCCACAGGAGCAAGCCAGAAAGAGACACCATCAACCCTGAGGGTCAGCATGTGATGCTCCCAG
GATACAGAGGACCATTCAAGCCATTCCAAAGTCCTGAACCTTGGAGACATTGTCTGAAATTCGC
ATATTTGTTCTGCCAAGTAGCTTCTGCTATAGTCGAGCTTCTCTTTTGTTGTCCCCACCCCCAG
GAGATCTACTCGCCTACAGATTTTTTTCTTTTATTCTTTGAAATTCTTTGGGGGAGGGGGGAGA
GTTAAAAAGAAGTTATTTCCAGATGCTCACCCCACCCCCGACACCCTTGCTTTCACTGATAGCC
AAGGATATAGACTACATTGTTCTTAAGGGTCACCTGATCTCTTGAGCCAGTTTGATCTAGCTGC
TTTTTGCCTTGTTCAAACTGAGGACCTGGAAGGGATCGTCAAACTTGCCTTAAATAAAGCCTGT
CACTAGAGGCTGACACTGGATGGTCACAGCCCTTCCTTGCATCTCCTCTCAGCTTGTCTCCCTG
TGAGTTTGCTCCAATCCCCTCAGAACCATACCTGCTCTGTGGTCCCCATTTTTGCCAGCCTTGT
CTCTAGGCTACTGGAGTATCTGACAAATCAGTCAAGCTCCCAGGAGTCTCTGGGAGACTGAAAA
ACTGGGGTCTCAAAGAAAGTGTAATGGAGAGTAAAACCACTAGGGGGCAGTATGGTGGGACCAC
AAAGCATCTACCCTTCTGTGTATATCTCCACACCTTTAACTCCTCTTGTTAGAGAGCTGCTTAT
TGTGGTGTTGACAAAATGTCTGATGACAGTTGGAAGCAATCCTGCATAACTTCATTTGCTTTTA
GACATCGACATATTTGATTGTCACCAGGCCATATTACCAATACTCACTTTGTTGGTACTATAAA
AGCTTTTGCCTCCCTAAAGTTTCTGTAAGTGGGGGGTTGATATGTGCCAATAATCTATGTCCCT
GCCTCACCCAAATGCTTGCACGGGCACATACGCATATGTAGCTGGATGCCAAGAGTACCATGTT
GACTAGGAACTGCCTGGAATTCAAAACAGAAAAGGGACAGCATGAATTTGAATAGCTCCCACTA
GATAAGCAATTTCCACGAAAACTTACCAAAAGCTAAAACTCCACAGAGCATTGTGAACCAAAGG
TAGACTCCCTTTGCATTAGTGAAAGTCTTACTCCCACTAATGGGACTTCGTTGTCTTCCAAAGC
AGTGGAAATGCAGGATCTCAACTTCATCCCCTGACAGTGGGCTCAGGAAACCAATAGATGGCTC
TTTCCAGCTCCCAACCAGTATTCCCGCTGCATCCGAATGCAAAGTGTTTGGCTGTGACTTTAGT
CTGAACATCATGTAGCCTCAGATGATGTTTGCCCATCTGCCTCCACGAAGTAAGGATATTATTG
TTGCCTTAATGGAAAAATGAAGATAAATCATGTTTAAAAAAATCTTTCCAAATAAAATGTTCCC
AATTCTG

hide sequence

RefSeq Acc Id:

XM_063274316 ⟹ XP_063130386

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	56,846,375 - 56,954,090 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012044	(Get FASTA)	NCBI Sequence Viewer
	XP_006252381	(Get FASTA)	NCBI Sequence Viewer
	XP_063130386	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83855	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014502.3
	ENSRNOP00000071263.1
	ENSRNOP00000083584.1
	ENSRNOP00000092952.1

RefSeq Acc Id:

NP_001012044 ⟸ NM_001012044

- UniProtKB:

Q5XI38 (UniProtKB/TrEMBL), A0A8I6AGS0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MARGSVSDEEMMELREAFAKVDTDGNGYISCNELNDLFKAACLPLPGYRVREITENLMATGDLD
QDGKISFDEFIKVFHGLKSTEVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVN
WINKALENDPDCRHVIPMNPNTDDLFNAVGDGIVLCKMVNLSVPDTIDERTINKKKLTPFTIQE
NLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGE
SLEDLMKLSPEELLLRWANYHLENAGCTKITNFSTDIKDSKAYYHLLEQVAPRGDEEGIPAVVI
DMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNKYPALHKPENQD
IDWGALEGETREERTFRNWMNSLGVNPGVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNRPPYP
KLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDIGG
GQKVNDDIIVNWVNTTLKEAQKSSSITSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDD
EEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV

hide sequence

RefSeq Acc Id:	XP_006252381 ⟸ XM_006252319
- Peptide Label:	isoform X1
- UniProtKB:	Q5XI38 (UniProtKB/TrEMBL), A0A8I6AGS0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARGSVSDEEMMELREAFAKVDTDGNGYISCNELNDLFKAACLPLPGYRVREITENLMATGDLD QDGKISFDEFIKVFHGLKSTEVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKYAFVN WINKALENDPDCRHVIPMNPNTDDLFNAVGDGIVLCKMVNLSVPDTIDERTINKKKLTPFTIQE NLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREGE SLEDLMKLSPEELLLRWANYHLENAGCTKITNFSTDIKDSKAYYHLLEQVAPRGDEEGIPAVVI DMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNKYPALHKPENQD IDWGALEGETREERTFRNWMNSLGVNPGVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNRPPYP KLGGNMKKLENCNYAVDLGKNQAKFSLVGIAGQDLNEGNRTLTLALVWQLMRRYTLNILEDIGG GQKVNDDIIVNWVNTTLKEAQKSSSITSFKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLDD EEKLNNAKYAISMARKIGARVYALPEDLVEVNPKMVMTVFACLMGKGMKRV hide sequence

Ensembl Acc Id:

ENSRNOP00000071263 ⟸ ENSRNOT00000082191

Ensembl Acc Id:

ENSRNOP00000014502 ⟸ ENSRNOT00000014502

Ensembl Acc Id:

ENSRNOP00000083584 ⟸ ENSRNOT00000105314

Ensembl Acc Id:

ENSRNOP00000092952 ⟸ ENSRNOT00000094863

RefSeq Acc Id:	XP_063130386 ⟸ XM_063274316
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AGS0 (UniProtKB/TrEMBL), Q5XI38 (UniProtKB/TrEMBL)

Protein Domains

Calponin-homology (CH) EF-hand

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K014-F1-model_v2	AlphaFold	A0A0G2K014	1-645	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699829

Promoter ID:

EPDNEW_R10352

Type:

initiation region

Name:

Lcp1_1

Description:

lymphocyte cytosolic protein 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	57,221,275 - 57,221,335	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308288	AgrOrtholog
BioCyc Gene	G2FUF-13137	BioCyc
Ensembl Genes	ENSRNOG00000010319	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000014502.6	UniProtKB/TrEMBL
	ENSRNOT00000082191.2	UniProtKB/TrEMBL
	ENSRNOT00000094863.1	UniProtKB/TrEMBL
	ENSRNOT00000105314.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.418.10	UniProtKB/TrEMBL
	EF-hand	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7125327	IMAGE-MGC_LOAD
InterPro	Actinin_actin-bd_CS	UniProtKB/TrEMBL
	Calponin-like_dom_sf	UniProtKB/TrEMBL
	Calponin_act_bd	UniProtKB/TrEMBL
	EF-hand-like_dom	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_Ca_bd	UniProtKB/TrEMBL
	Fimbrin/Plastin	UniProtKB/TrEMBL
KEGG Report	rno:306071	UniProtKB/TrEMBL
MGC_CLONE	MGC:95070	IMAGE-MGC_LOAD
NCBI Gene	306071	ENTREZGENE
PANTHER	PLASTIN-2	UniProtKB/TrEMBL
	PTHR19961	UniProtKB/TrEMBL
Pfam	EF_hand_5	UniProtKB/TrEMBL
	PF00307	UniProtKB/TrEMBL
PhenoGen	Lcp1	PhenoGen
PROSITE	ACTININ_1	UniProtKB/TrEMBL
	ACTININ_2	UniProtKB/TrEMBL
	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
	PS50021	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000010319	RatGTEx
SMART	EFh	UniProtKB/TrEMBL
	SM00033	UniProtKB/TrEMBL
Superfamily-SCOP	Calponin-homology	UniProtKB/TrEMBL
	SSF47473	UniProtKB/TrEMBL
UniProt	A0A0G2K014_RAT	UniProtKB/TrEMBL
	A0A8I6AGS0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6G984_RAT	UniProtKB/TrEMBL
	Q5XI38	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Lcp1	lymphocyte cytosolic protein 1	Lcp1_predicted	lymphocyte cytosolic protein 1 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Lcp1_predicted	lymphocyte cytosolic protein 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD