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Gene: Fer1l4 (fer-1-like family member 4) Rattus norvegicus

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Symbol:

Fer1l4

Name:

fer-1-like family member 4

RGD ID:

1308250

Description:

Predicted to enable metal ion binding activity. Predicted to be involved in plasma membrane organization. Predicted to be located in membrane. Orthologous to human FER1L4 (fer-1 like family member 4 (pseudogene)); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

fer-1-like 4; fer-1-like 4 (C. elegans); fer-1-like protein 4; fer-1-like protein 4-like; LOC100911434; LOC296307

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FER1L4 (fer-1 like family member 4 (pseudogene))	RGD	RGD
Mus musculus (house mouse):	Fer1l4 (fer-1 like family member 4)	RGD	RGD
Canis lupus familiaris (dog):	FER1L4 (fer-1 like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FER1L4 (fer-1 like family member 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Fer1l4 (fer-1 like family member 4)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	FER1L4 (fer-1 like family member 4 (pseudogene))	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	FER1L4 (fer-1 like family member 4 (pseudogene))	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	fer1l4 (fer-1 like family member 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	fer-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector)
Drosophila melanogaster (fruit fly):	mfr	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mgc107884	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	fer1l4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	164,996,183 - 165,031,719 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	164,996,183 - 165,031,719 (-)	Ensembl				GRCr8
mRatBN7.2	3	144,536,099 - 144,571,634 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	144,536,099 - 144,571,634 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	148,401,697 - 148,437,422 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	157,018,973 - 157,054,698 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	154,758,499 - 154,794,224 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	151,564,604 - 151,600,140 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	151,564,604 - 151,600,140 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	157,929,222 - 157,964,758 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	146,427,611 - 146,463,147 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	143,257,857 - 143,293,409 (-)	NCBI		Celera
RGSC_v3.1	3	146,333,345 - 146,368,742 (-)	NCBI
Cytogenetic Map	3	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dimethylhydrazine (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,4'-trichlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chromium(6+) (ISO)

clothianidin (ISO)

copper atom (EXP)

copper(0) (EXP)

dexamethasone (ISO)

dibutyl phthalate (ISO)

entinostat (ISO)

epoxiconazole (ISO)

folic acid (ISO)

genistein (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

mono(2-ethylhexyl) phthalate (ISO)

okadaic acid (ISO)

paracetamol (ISO)

PCB138 (ISO)

pentanal (ISO)

pinostrobin (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

thimerosal (ISO)

trichloroethene (EXP)

triclosan (ISO)

triptonide (ISO)

tris(2-butoxyethyl) phosphate (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

plasma membrane organization (IBA)

Cellular Component

membrane (IEA)

Molecular Function

metal ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Fer1l4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	164,996,183 - 165,031,719 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	164,996,183 - 165,031,719 (-)	Ensembl				GRCr8
mRatBN7.2	3	144,536,099 - 144,571,634 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	144,536,099 - 144,571,634 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	148,401,697 - 148,437,422 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	157,018,973 - 157,054,698 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	154,758,499 - 154,794,224 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	151,564,604 - 151,600,140 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	151,564,604 - 151,600,140 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	157,929,222 - 157,964,758 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	146,427,611 - 146,463,147 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	143,257,857 - 143,293,409 (-)	NCBI		Celera
RGSC_v3.1	3	146,333,345 - 146,368,742 (-)	NCBI
Cytogenetic Map	3	q42	NCBI

FER1L4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	35,558,737 - 35,607,562 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	35,558,866 - 35,607,494 (-)	Ensembl			hg38	GRCh38
GRCh37	20	34,146,507 - 34,195,484 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	33,609,921 - 33,651,008 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	20	30,894,820 - 30,943,779 (-)	NCBI		Celera
Cytogenetic Map	20	q11.22	NCBI
HuRef	20	30,924,013 - 30,973,281 (-)	NCBI		HuRef
CHM1_1	20	34,047,835 - 34,097,104 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	37,279,572 - 37,328,533 (-)	NCBI		T2T-CHM13v2.0

Fer1l4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	155,861,059 - 155,894,939 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	155,861,059 - 155,894,867 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	156,019,139 - 156,053,019 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	156,019,139 - 156,052,947 (-)	Ensembl			mm10	GRCm38
MGSCv37	2	155,844,876 - 155,878,683 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	155,710,581 - 155,744,081 (-)	NCBI		MGSCv36	mm8
Celera	2	161,953,004 - 161,986,811 (-)	NCBI		Celera
Cytogenetic Map	2	H1	NCBI
cM Map	2	77.32	NCBI

FER1L4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	24,509,734 - 24,543,589 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	24,154,950 - 24,188,711 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	25,202,278 - 25,236,121 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	25,202,283 - 25,236,147 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	24,488,664 - 24,522,490 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	24,583,825 - 24,617,532 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	25,023,084 - 25,056,904 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

FER1L4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	17	38,900,118 - 38,945,936 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	44,021,603 - 44,027,795 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Variants

Variants in Fer1l4
101 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	32
Count of miRNA genes:	29
Interacting mature miRNAs:	32
Transcripts:	ENSRNOT00000026451
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	130656562	169034231	Rat
1598877	Bp285	Blood pressure QTL 285	1.5	0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	120538241	165538241	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141074471	169034231	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
2298477	Eau4	Experimental allergic uveoretinitis QTL 4		0.0011	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	3	137398739	169034231	Rat
61335	Bp20	Blood pressure QTL 20	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141339236	155617360	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141339013	162184794	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1300173	Rf11	Renal function QTL 11	3.38		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	121056165	145956249	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	131635904	169034231	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	122438700	167438700	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	127162703	168026850	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	118839124	163839124	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	121056165	157309487	Rat
5686842	Rf59	Renal function QTL 59			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	3	140069424	146976080	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	130193298	161695983	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	130656562	169034231	Rat
8552952	Pigfal13	Plasma insulin-like growth factor 1 level QTL 13			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	138799500	169034231	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	124122556	169034231	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	5	44	18	24	2	34	2	6	127	49	3	33	61	68	22	2	2

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC118414	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474050	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000026451 ⟹ ENSRNOP00000026451

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	164,996,183 - 165,031,719 (-)	Ensembl
mRatBN7.2 Ensembl	3	144,536,099 - 144,571,634 (-)	Ensembl
Rnor_6.0 Ensembl	3	151,564,604 - 151,600,140 (-)	Ensembl

RefSeq Acc Id:

NM_001106534 ⟹ NP_001100004

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	164,996,183 - 165,031,719 (-)	NCBI
mRatBN7.2	3	144,536,099 - 144,571,634 (-)	NCBI
Rnor_6.0	3	151,564,604 - 151,600,140 (-)	NCBI
Rnor_5.0	3	157,929,222 - 157,964,758 (-)	NCBI
RGSC_v3.4	3	146,427,611 - 146,463,147 (-)	RGD
Celera	3	143,257,857 - 143,293,409 (-)	RGD

Sequence:

show sequence

ATGGCTCTGACTGTGTGTGTGAGGCACCTAACAGGGCTGCCGGGCATCCATGACCGACAAGTGA
GGCTCTGCTTCCGAGGCTTTACTCAGAAAACAAGGAAAATTCACTGTGGCCGAGAAGCAGACGT
TGGTGAGCTGTTCCGTTGGCCCCACTACGGATCTCCACTGGCTGGGGAGAGTCTGTCTGTGCAG
GTGGTCAACTGTAGCCGAGTGTTCAGCCCCAGGCCCCTGGGAACCCTGGTGATTTCTCTGCAGC
GGCTGCAAAACACTGGACATTTGGTGCTGAGGGAAGCCCTGGTGGATGAGAGACTCCGGGTATC
CCCGATCCAAGTGGAGCTTGACCTAAAGTATCAGCCCCCTGAGGGAGCTGCTGGAACCTGGGCA
GAGGAGGACTTTGGGGCACCCATTCGAGACAGCTTAGAGTTGATCATCCCCAATGTGGGCTTCC
AGGATATGGAGCCTGGGGAGGCCCAGCTGGAGCGACGGGCAGTGGCTATGGGCCGCAGGCTAGC
CCAAAGCCTAGGGACACAGGATGACGAAGAGAATGAGCTGGAGCTGGAGCTGGACCTGGAGGAA
CCTGACGTGGAGATTTCTGGGGTGGTGTTCAGCCCCCTCAAAAGCCGCGCCCTGGGTTTACCTC
GCAGGGATCCCTTCAAGGCGTGCAAAGCCCAGGACTTCCAGGTGGGGGTCACAGTGCTTGAGGC
CCAGAAACTGGTGGGAGTCAATATTAACCCCTATGTCACTGTTCGCGTGGGGGATCAGCGCCGA
GTGACTGCCACACAACGTGGAACCAATTGCCCCTTCTACAATGAGTACTTCCTGTTTGAATTTC
ATGAAACTCGGCTTCATCTCCAAGACTTGCTGCTGGAAATAACTGCTTTCCACTCGCAGACTCT
CCCGTTTATGGCCACCAGAATAGGAACCTTCAGGATGGACTTAGGGATGGCCTTGGACCAGCCA
GATGGCCACTTCCACCAAAAGTGGGCTCCTTTACATGACCCCCGTGACACCCGTGCGGGAACCA
AGGGCTTCATCAAGATCACCTTGTCTGTGAGGGCACGTGGGGACCTTCCCCTTCCACCACCACC
CTCAACCCCAGGGACCAGTGCAGACATAGAGAAGAATCTACTCCTGCCACGTGGGGTGCAGGCT
GAGAGACCATGGGCAAGGCTGCGAGTCCGAGTGTACCGTGCAGAGGGGCTTCCCACAGTGCGCA
CGGGGCTGCTGGGCAGTCTAGCCCGTGCCCTGCATGACCAACATGTCCTCCTGGACCCATATGT
GCGGGTGAGCTTCCTGGGGCAGCAGGGTGAGACTTCGGTTCGGGGAGAGGAGACAGCGCCCGAG
TGGAACGAGCAGTTGAGCTTCGTGGAACTCTTCCCGCCGCTAACGCGCAGCCTTCGCCTGCAGC
TGCGGGACGACGCACCTCTTGCAGATGTGGCACTCGCTACACACATGCTAGACCTGAGGCAGAT
CTCAAACTCGGGTCGTGCAGCGGGGTTTAACCCCACTTTCGGTCCAGCCTGGGTGCCCCTCTAT
GGCTCACTCCCCAGTGGCAGGTTCCGGGATGGTCTTCAAGGTCTCAATGAAGGCCTCGGGGAAG
GCATTTGGTTCCGGGGTCGACTTCTGGTAGCTGTGTCCATGGAAGTATTTGAAGGCAGAGTTGA
ACCTAAATCCTCCCAGACCACACAAGGGTCCGGATTGTCCCGGCTCACTGGAAAGAAGAAAAAG
AAGAAGGAGAAGACCAAGCAGGGCCAGACCCCAGCTGGCACTTTACAGCCTGCCAACGCCAGCA
CGGAAGTGGGTGTGCCCGAGATTCCGAGCTCAATGGAGGTGGACATGGAAGAGCTGCTGCCTCT
GCCAGAGAATGCTCTGGCACCCTGTGAAGATTTCCTGCTTTTCGGGGTGCTCTTTGAGGCCACC
ATGATTGACCCTTCCCTGGCCAAGAAACCCATCAGCCTGGAGATTTCCATTGGTCATGCAGGCC
GCCGGGAAGAGCAATTGGGTCCAGGATCAAGGGCTGATGGGGGATCTGAAGGCAGCACACTGGA
AGCTCAGCCTCTTCTGGAATCTGAGGACAGAGGGGCAGGGCAGGAGGAGCAAGAGTTGCTGGGG
ACACCTGCTCAGTGGCCTGAACCTGTGGAGGGCAATGGGCCGTATCTCTGCTTGCCTCTGCGTC
ACCGAAAGCCCTGCTTACATGTATGGAGCCGCTGGGAGGATTATACTTGGCGCCTGCATAGCAG
TAACAGTGTGTGCAAAGTAGCTGAGAGACTGGACCATGGCCTGCAGGAGGTTGAGAAGATACAG
CGCAGGTCAGTGCTGGGTGCCTGTACACGACTCAAGCAGACTCTGGAAGAGCTAGTGGCTGGCA
GCAGACAATTTTGCCACGGCGCTGAGCGTAGGACGATGACTCGACCCAATGCCCTGGATCGTTG
CCGAGCGAAACTCCTGACACACAGCCTGAATCTGATGGCAAGGCAAGGATTGCGGCTTTTACGG
AGCCTGAGGCAGAACAACATTCAGAGGACTGTGGCACTGGCGAAGAAGCTCCTGGCAAAGCTGC
ACTTCCTGGCTCAGGAGCCACAGCCACCCCTCCCTGATGTGCTGGTCTGGATGTTCAGTGGCCA
GCGCCGTGTGGCCTATGCCCGGGTCCCTGCCCAGGATGTGCTGTTCTCTGTGGTTGAGGAGGAG
CGAGGCCGAGACTGTGGGAAGATCCAGAGTCTGCTACTCACAGCACCTGGGGCAGCCCCTGGGG
AAGTCTGTGCCAAGTTGGAGCTCTTCCTGTGGCTGGGGCTGGGTAAGCAATCGAAGGCTTGCCC
GTCTGAGCTGCCCCCAGATCTTCTGCCTGAACCCTCACGTGGGCTGCCCCACAGCCTATACCGG
GATGACTTCAGCTACTTCCAGATGCGGGCTCACCTGTACCAGGCCCGAGGTGTGTTGGCAGCAG
ATGACAGTGGCCTCTCGGACCCCTTTGCCCGTGTCCTCATCTCTACCCAGTGCAAGACCACACG
GGTCTTGGAGCAGACACTGAGCCCCCTGTGGGATGAACTCTTGGTATTTGACCAGCTGATCGTG
GATGGGAAGCGGGAGCATTTGCGGGAGGAGCCTCCTCTAGTGGTCATCAATGTCTTTGACCACA
ATAAGTTCGGCTCTGCTGTGTTCCTTGGCAGGGCATTTGCAGCCCCAAGGGTAAAGTTGATAGA
GGACTCATATCAGCGCCCTGAGCTGCAGTTCTTCCCCCTGAGGAAGGGACCTCAGGCTGCTGGA
GAAGTCATTGCTACCTTTGAACTTATCGAGCTGGATTACAGTGGCCATCTTGAGCCCTCAGTGC
CCAGTGATGTGGAGCCCCAGGACCTGGCTTCACTGGTCGAACCCATCTCTGGACACCTGTCTCT
GCCTGCCAGTGTGCGCCCTGTGCTCCGAGAGTTCCGTGTCGAGGTACTGTTCTGGGGTCTTCGA
GGACTGGGCCGTGTACACCTGTTTGAAGTGGAAAAGCCTCAGGTTGTTCTGGAAGTGGCTGGGA
GACGTGTGGAGTCCGAAGTTCTGGCCAACTACTGCGAGAACCCTAACTTCACAGAGCTCGTCCA
GTGTGTGACAGTGGACTTGCCAGAACAGCCATATCTGCAGCCCCCGCTGAGCATCTTGGTGATT
GAGCGCCGGGCCTTTGGCCGAACTGTTCTTGTGGGTTCCCATATTGTCCCTCACATGCTTAGAT
TCACACTCCAGGGTCAGGAGGATCCCCGAGAGGAGGAAAGAACAGAGGAGGAGACAAGGGGCCT
GGTGCCACAAGGGCTTCAAGGAGAGAAGTCTCTGGCTGAAGCAGGAATATCCAGACAGCGTCTG
AAGGCTCCTCTGAAGAAGCTCACCTTAGGGCTCCTGGGTCAAGGCCCTGAGCTGGAGGAAGCCA
TCCCAGATCCACAGGAGATGGACTGGTGGTCCAAGTACTATGCCTCCCTGCAGGAGCTCCAGGG
GCAGTCCAGCTCCGATGATGACGAGATGGACGATGCCAGAGATCCAGATGGGACGCACCTCATT
TCTGGGGAGAGAGAAGCCCAGGAGCAGGGGGAGACTGATATCAAAGTCTCTGTGCCTCGGAAGA
AAGCAATCGCCACCCTGAAGATCTACCACAGCTCCCTAGAGGATGAGTTTAACCACTTTGAAGA
CTGGCTGAGTGTGTTCCCCCTGTACAGAGGACAAGGCGGCCAGGAAGGGGATGGAGAGGAAGCA
TCTGGACACTTTGTGGGCAAGTTCAAGGGCTCCTTCCTAATTTACCCTGAGTCAGAGGCCAAAT
CCTTCTCTGAGCCTCAGATCTCCAGGGGGATCCCCCAGAACCGGCCCATCAAGCTTCTGGTCAG
AGTGTATATAGTGAAGGCTACCAACCTGGCTCCTGCAGACCCCAATGGCAAGGCAGACCCCTAT
GTGGTGGTGAGCGCCGGCAAGGAGCAGCGGGACACTAAGGAGCGCTATATCCCCAAGCAACTGA
ATCCCATCTTTGGAGAGGTCCTGGAACTGAGTGTCTCTCTCCCAGCTGAGCCAGAGCTGACTGT
GGCCATATTTGACCATGACCTCGTGGGTTCTGATGACCTCATCGGGGAGACCCACATTGACCTG
GAAAACAGATTCTATAGCCACCACAGAGCCAATTGTGGGCTGGCCTCCCAGTATGATGTGGATG
GGTACAATGCCTGGCGAGATGCATTCCGGCCTTCACAGATCCTGGCCGGGTTGTGCCAGCGCTG
TGGCCTTCCTATCCCTGAGTACCGAGCTGGGGCTGTCAAAGTGGGCAGCAGAGTCTTCCTGACA
CCATCTGAGGCCCTGCCTCCAGATGGCCGGGATCCCAAGGGGGCAAATGAGGCTTCTGAAGAGG
CCCAAGCGTTGCTGGTGTTGAGGCGCTGGCAGGAGATGCCAGGACTTGGAATCCAACTGGTACC
TGAGCATGTGGAAACGCGGCCTCTGTACCATCCCCGCAGCCCAGGGCTGCTGCAGGGATCCCTG
CACATGTGGATTGACGTATTCCCCAGTGATGTGCCTGCCCCACCCCCAGTTGACATCAAGCCTC
GGCAGCCAATCAGCTATGAGCTCAGAGTTGTCATCTGGAACACAGACGACGTGGTTCTGGATGA
TGTGAATCCACTCACTGGGGAGATGTCAAGTGACATCTATGTGAAAAGCTGGGTGAAGGGTCTA
GAGCACGACAGACAGGAGACAGATGTGCACTTCAACTCCCTGACCGGAGAGGGCAACTTCAACT
GGCGCTTTGTGTTCCGCTTTGACTACCTGCCCACGGAGCGGGAGGTGAGCATCCGGCGCAAGCC
TGGACCCTTCGCCCTGGAGGAGGCTGAGTTCCGGCAGCCAGCTGTGCTGGTCCTGCAGGTCTGG
GACTACGACCGAGTCTCTGCCAACGACTTTCTTGGGTCCCTGGAGCTGCAGCTACCAGACATGG
TGAGGGGGGCCCGGGACCCTGAGCACTGTACTGTTCGACTAGCCCTTGATGGGGCAGGGCCGAG
GTGCAATCTGTTTCGCTGCCGGCGGTTGCGGGGCTGGTGGCCCGTGGTGAAGACGAAGGACATG
GAAGATGTGGAGCGGGAGGCCAGAGAGGCTCAGGCTGGCAAGAAAAGGAAGAGGAAGAGGAGGA
AGGGTTGGCCGGAGGACCTGGAGTTCACAGACACAGGGGGCAACGTCTACATCCTCACAGGGAA
GGTTGAGGCGGAGTTTGAACTGCTAACTGTAGAGGAGGCAGAGAAGCGGCCGGTTGGGAAGGGG
CGAAAGGAGCCAGAGCCTCTGGAGAAGCCCAATCGCCCCAAAACCTCCTTCAACTGGTTTGTGA
ACCCCCTCAAGACTTTTGTCTTCTTCATCTTGCGCCGGTACTGGCGGATCCTGGTGGTGCTGCT
GCTGCTGGCGCTAATCACCATCTTCCTGCTCCTTGTCTTCTACACCATCCCTGGACAGATCAGC
GAGGTCATCTTCAGCCCCATCAACAAACACTAATTCAAGTGACCAGGGACACACCTCAGGGTTT
TTCAAACCTGCTCTGGAAGTCCCTCCTACCAATGCGACCTGGAAGGGTTCAGTCCTTGGGTTCA
ATAAACTTTCTCAGAGGC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100004	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL85878	(Get FASTA)	NCBI Sequence Viewer
	EDL85879	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000026451
	ENSRNOP00000026451.5

RefSeq Acc Id:

NP_001100004 ⟸ NM_001106534

- UniProtKB:

D4ABP2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALTVCVRHLTGLPGIHDRQVRLCFRGFTQKTRKIHCGREADVGELFRWPHYGSPLAGESLSVQ
VVNCSRVFSPRPLGTLVISLQRLQNTGHLVLREALVDERLRVSPIQVELDLKYQPPEGAAGTWA
EEDFGAPIRDSLELIIPNVGFQDMEPGEAQLERRAVAMGRRLAQSLGTQDDEENELELELDLEE
PDVEISGVVFSPLKSRALGLPRRDPFKACKAQDFQVGVTVLEAQKLVGVNINPYVTVRVGDQRR
VTATQRGTNCPFYNEYFLFEFHETRLHLQDLLLEITAFHSQTLPFMATRIGTFRMDLGMALDQP
DGHFHQKWAPLHDPRDTRAGTKGFIKITLSVRARGDLPLPPPPSTPGTSADIEKNLLLPRGVQA
ERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQHVLLDPYVRVSFLGQQGETSVRGEETAPE
WNEQLSFVELFPPLTRSLRLQLRDDAPLADVALATHMLDLRQISNSGRAAGFNPTFGPAWVPLY
GSLPSGRFRDGLQGLNEGLGEGIWFRGRLLVAVSMEVFEGRVEPKSSQTTQGSGLSRLTGKKKK
KKEKTKQGQTPAGTLQPANASTEVGVPEIPSSMEVDMEELLPLPENALAPCEDFLLFGVLFEAT
MIDPSLAKKPISLEISIGHAGRREEQLGPGSRADGGSEGSTLEAQPLLESEDRGAGQEEQELLG
TPAQWPEPVEGNGPYLCLPLRHRKPCLHVWSRWEDYTWRLHSSNSVCKVAERLDHGLQEVEKIQ
RRSVLGACTRLKQTLEELVAGSRQFCHGAERRTMTRPNALDRCRAKLLTHSLNLMARQGLRLLR
SLRQNNIQRTVALAKKLLAKLHFLAQEPQPPLPDVLVWMFSGQRRVAYARVPAQDVLFSVVEEE
RGRDCGKIQSLLLTAPGAAPGEVCAKLELFLWLGLGKQSKACPSELPPDLLPEPSRGLPHSLYR
DDFSYFQMRAHLYQARGVLAADDSGLSDPFARVLISTQCKTTRVLEQTLSPLWDELLVFDQLIV
DGKREHLREEPPLVVINVFDHNKFGSAVFLGRAFAAPRVKLIEDSYQRPELQFFPLRKGPQAAG
EVIATFELIELDYSGHLEPSVPSDVEPQDLASLVEPISGHLSLPASVRPVLREFRVEVLFWGLR
GLGRVHLFEVEKPQVVLEVAGRRVESEVLANYCENPNFTELVQCVTVDLPEQPYLQPPLSILVI
ERRAFGRTVLVGSHIVPHMLRFTLQGQEDPREEERTEEETRGLVPQGLQGEKSLAEAGISRQRL
KAPLKKLTLGLLGQGPELEEAIPDPQEMDWWSKYYASLQELQGQSSSDDDEMDDARDPDGTHLI
SGEREAQEQGETDIKVSVPRKKAIATLKIYHSSLEDEFNHFEDWLSVFPLYRGQGGQEGDGEEA
SGHFVGKFKGSFLIYPESEAKSFSEPQISRGIPQNRPIKLLVRVYIVKATNLAPADPNGKADPY
VVVSAGKEQRDTKERYIPKQLNPIFGEVLELSVSLPAEPELTVAIFDHDLVGSDDLIGETHIDL
ENRFYSHHRANCGLASQYDVDGYNAWRDAFRPSQILAGLCQRCGLPIPEYRAGAVKVGSRVFLT
PSEALPPDGRDPKGANEASEEAQALLVLRRWQEMPGLGIQLVPEHVETRPLYHPRSPGLLQGSL
HMWIDVFPSDVPAPPPVDIKPRQPISYELRVVIWNTDDVVLDDVNPLTGEMSSDIYVKSWVKGL
EHDRQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREVSIRRKPGPFALEEAEFRQPAVLVLQVW
DYDRVSANDFLGSLELQLPDMVRGARDPEHCTVRLALDGAGPRCNLFRCRRLRGWWPVVKTKDM
EDVEREAREAQAGKKRKRKRRKGWPEDLEFTDTGGNVYILTGKVEAEFELLTVEEAEKRPVGKG
RKEPEPLEKPNRPKTSFNWFVNPLKTFVFFILRRYWRILVVLLLLALITIFLLLVFYTIPGQIS
EVIFSPINKH

hide sequence

Ensembl Acc Id:

ENSRNOP00000026451 ⟸ ENSRNOT00000026451

Protein Domains

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ABP2-F1-model_v2	AlphaFold	D4ABP2	1-1994	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308250	AgrOrtholog
BioCyc Gene	G2FUF-47109	BioCyc
Ensembl Genes	ENSRNOG00000019467	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000026451	ENTREZGENE
	ENSRNOT00000026451.6	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.150	UniProtKB/TrEMBL
InterPro	C2_Ca-dep	UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/TrEMBL
	C2A_Ferlin	UniProtKB/TrEMBL
	C2B_Ferlin	UniProtKB/TrEMBL
	C2C_Ferlin	UniProtKB/TrEMBL
	C2D_Ferlin	UniProtKB/TrEMBL
	C2E_Ferlin	UniProtKB/TrEMBL
	C2F_Ferlin	UniProtKB/TrEMBL
	FerB	UniProtKB/TrEMBL
	FerIin-typ	UniProtKB/TrEMBL
	Ferlin	UniProtKB/TrEMBL
	Ferlin_C	UniProtKB/TrEMBL
	Ferlin_DSRM	UniProtKB/TrEMBL
KEGG Report	rno:296307	UniProtKB/TrEMBL
NCBI Gene	296307	ENTREZGENE
PANTHER	PTHR12546	UniProtKB/TrEMBL
	PTHR12546:SF36	UniProtKB/TrEMBL
Pfam	dsrm_Ferlin	UniProtKB/TrEMBL
	FerB	UniProtKB/TrEMBL
	FerI	UniProtKB/TrEMBL
	Ferlin_C	UniProtKB/TrEMBL
	PF00168	UniProtKB/TrEMBL
PhenoGen	Fer1l4	PhenoGen
PROSITE	PS50004	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000019467	RatGTEx
SMART	FerB	UniProtKB/TrEMBL
	FerI	UniProtKB/TrEMBL
	SM00239	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49562	UniProtKB/TrEMBL
UniProt	D4ABP2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Fer1l4	fer-1-like family member 4	LOC100911434	fer-1-like protein 4-like	Data merged from RGD:6493003	737654	PROVISIONAL
2015-06-23	Fer1l4	fer-1-like family member 4	Fer1l4	fer-1-like 4 (C. elegans)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-07-05	LOC100911434	fer-1-like protein 4-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Fer1l4	fer-1-like 4 (C. elegans)	Fer1l4_predicted	fer-1-like 4 (C. elegans) (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Fer1l4_predicted	fer-1-like 4 (C. elegans) (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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