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Gene: Pld3 (phospholipase D family, member 3) Rattus norvegicus

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Symbol:

Pld3

Name:

phospholipase D family, member 3

RGD ID:

1308248

Description:

Predicted to enable single-stranded DNA 5'-3' DNA exonuclease activity. Predicted to be involved in myotube differentiation and regulation of cytokine production involved in inflammatory response. Predicted to be located in bounding membrane of organelle; endoplasmic reticulum membrane; and lysosomal lumen. Human ortholog(s) of this gene implicated in spinocerebellar ataxia 46. Orthologous to human PLD3 (phospholipase D family member 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

(S,S)-bis(monoacylglycero)phosphate synthase PLD3; 5'-3' exonuclease PLD3; choline phosphatase 3; LOC361527; MGC109410; phosphatidylcholine-hydrolyzing phospholipase D3; phospholipase D3; PLD 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PLD3 (phospholipase D family member 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Pld3 (phospholipase D family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pld3 (phospholipase D family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PLD3 (phospholipase D family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PLD3 (phospholipase D family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pld3 (phospholipase D family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PLD3 (phospholipase D family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PLD3 (phospholipase D family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pld3 (phospholipase D family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	KRT26 (keratin 26)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	PLD3 (phospholipase D family member 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pld3 (phospholipase D family member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	pld3 (phospholipase D family, member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG9248	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F09G2.8	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	pld3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	91,949,465 - 91,971,834 (-)	NCBI		GRCr8
mRatBN7.2	1	82,821,863 - 82,844,280 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	82,821,875 - 82,844,072 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	88,224,510 - 88,236,258 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	96,711,811 - 96,723,540 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	89,980,373 - 89,992,121 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	84,339,269 - 84,361,686 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	84,339,261 - 84,353,725 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	85,556,092 - 85,578,621 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	82,612,833 - 82,624,575 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	82,690,945 - 82,702,686 (-)	NCBI
Celera	1	77,234,697 - 77,246,439 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease 19 (ISO)

Carpenter syndrome 2 (ISO)

Charcot-Marie-Tooth disease (ISO)

Charcot-Marie-Tooth disease type 4 (ISO)

Charcot-Marie-Tooth disease type 4F (ISO)

congenital hypoplastic anemia (ISO)

COVID-19 (ISO)

craniosynostosis 1 (ISO)

Diamond-Blackfan anemia (ISO)

maple syrup urine disease (ISO)

maturity-onset diabetes of the young type 1 (ISO)

spinocerebellar ataxia 46 (ISO)

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dibromoethane (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2-bromohexadecanoic acid (ISO)

2-nitrotoluene (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

actinomycin D (ISO)

aflatoxin B1 (EXP)

all-trans-retinoic acid (ISO)

amitrole (EXP)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol AF (ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cycloheximide (ISO)

cytarabine (ISO)

DDE (ISO)

decabromodiphenyl ether (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

diethylstilbestrol (ISO)

dopamine (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fipronil (EXP)

folic acid (ISO)

genistein (ISO)

glycidol (ISO)

indometacin (ISO)

ivermectin (ISO)

lipopolysaccharide (ISO)

menadione (ISO)

methimazole (EXP)

methotrexate (ISO)

methyl carbamate (ISO)

nickel sulfate (ISO)

nitrofen (EXP)

Nutlin-3 (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (EXP)

phenylmercury acetate (ISO)

potassium dichromate (ISO)

propiconazole (EXP)

quercetin (ISO)

rotenone (EXP)

SB 431542 (ISO)

sodium arsenite (ISO)

Soman (EXP)

succimer (ISO)

sulfadimethoxine (EXP)

sunitinib (ISO)

testosterone (ISO)

thapsigargin (EXP)

theophylline (ISO)

thioacetamide (EXP)

topotecan (EXP)

tributylstannane (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA metabolic process (IEA)

immune system process (IEA)

inflammatory response (IEA)

lipid metabolic process (IEA)

myotube differentiation (IEA,ISO,ISS)

regulation of cytokine production involved in inflammatory response (IEA,ISO,ISS)

Cellular Component

early endosome membrane (IEA,ISO,ISS)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA,ISO,ISS)

endosome (IEA)

endosome membrane (IEA)

Golgi apparatus (IEA)

Golgi membrane (IEA,ISO,ISS)

late endosome membrane (IEA,ISO,ISS)

lysosomal lumen (IEA,ISO,ISS)

lysosomal membrane (IEA,ISO)

lysosome (IEA)

membrane (IEA)

Molecular Function

catalytic activity (IEA)

exonuclease activity (IEA)

hydrolase activity (IEA)

hydrolase activity, acting on ester bonds (IEA)

metal ion binding (IEA)

nuclease activity (IEA)

phospholipase D activity (ISO)

protein binding (ISO)

single-stranded DNA 5'-3' DNA exonuclease activity (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:9813063	PMID:12477932	PMID:15489334	PMID:15794758	PMID:19056867	PMID:19199708	PMID:22102906	PMID:22428023	PMID:23106098	PMID:23376485	PMID:23533145	PMID:28128235
PMID:29368044	PMID:29386126	PMID:30111894	PMID:30312375

Genomics

Comparative Map Data

Pld3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	91,949,465 - 91,971,834 (-)	NCBI		GRCr8
mRatBN7.2	1	82,821,863 - 82,844,280 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	82,821,875 - 82,844,072 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	88,224,510 - 88,236,258 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	96,711,811 - 96,723,540 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	89,980,373 - 89,992,121 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	84,339,269 - 84,361,686 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	84,339,261 - 84,353,725 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	85,556,092 - 85,578,621 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	82,612,833 - 82,624,575 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	82,690,945 - 82,702,686 (-)	NCBI
Celera	1	77,234,697 - 77,246,439 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

PLD3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	40,348,695 - 40,378,485 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	40,348,456 - 40,389,472 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	40,854,602 - 40,884,392 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	45,546,447 - 45,576,230 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	45,557,388 - 45,576,229	NCBI
Celera	19	37,653,871 - 37,683,932 (+)	NCBI		Celera
Cytogenetic Map	19	q13.2	NCBI
HuRef	19	37,289,542 - 37,319,862 (+)	NCBI		HuRef
CHM1_1	19	40,854,014 - 40,884,087 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	43,169,216 - 43,199,111 (+)	NCBI		T2T-CHM13v2.0

Pld3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	27,231,090 - 27,252,511 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	27,231,425 - 27,252,643 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	27,531,367 - 27,553,229 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	27,532,000 - 27,553,218 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	28,317,037 - 28,338,131 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	27,240,778 - 27,261,872 (-)	NCBI		MGSCv36	mm8
Celera	7	22,114,471 - 22,135,478 (-)	NCBI		Celera
Cytogenetic Map	7	A3	NCBI
cM Map	7	15.92	NCBI

Pld3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955578	884,700 - 894,433 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955578	884,700 - 905,426 (-)	NCBI	ChiLan1.0	ChiLan1.0

PLD3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	46,611,063 - 46,640,986 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	48,481,721 - 48,513,247 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	37,396,475 - 37,426,425 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	45,910,035 - 45,939,343 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	45,910,035 - 45,939,343 (+)	Ensembl	panpan1.1		panPan2

PLD3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	113,305,146 - 113,322,705 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	113,305,445 - 113,312,632 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	112,707,088 - 112,724,610 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	113,903,509 - 113,921,055 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	113,901,791 - 113,920,989 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	113,462,768 - 113,480,306 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	113,095,268 - 113,112,804 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	114,089,264 - 114,106,809 (-)	NCBI		UU_Cfam_GSD_1.0

Pld3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	14,313,433 - 14,335,872 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936661	2,741,234 - 2,767,121 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936661	2,741,523 - 2,763,945 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLD3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	48,645,417 - 48,669,430 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	48,645,347 - 48,667,394 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	44,511,277 - 44,516,457 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLD3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	34,804,574 - 34,833,975 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	34,804,500 - 34,836,333 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	12,898,435 - 12,929,234 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pld3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624925	361,418 - 382,172 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624925	361,306 - 382,172 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Pld3
168 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	115
Count of miRNA genes:	97
Interacting mature miRNAs:	104
Transcripts:	ENSRNOT00000057177
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49393172	94393172	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	43333002	88333002	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	72197680	90508767	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	82174743	118944897	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	80592172	125592172	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	32737273	90665040	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	53863041	90532583	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
152025249	Scl82	Serum cholesterol level QTL 82	4.77		blood cholesterol amount (VT:0000180)		1	50343510	99980958	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	78430754	91209302	Rat

Markers in Region

RH141115

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	82,821,974 - 82,822,166 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	84,339,381 - 84,339,572	NCBI	Rnor6.0
Rnor_5.0	1	85,556,202 - 85,556,393	UniSTS	Rnor5.0
RGSC_v3.4	1	82,612,943 - 82,613,134	UniSTS	RGSC3.4
Celera	1	77,234,807 - 77,234,998	UniSTS
RH 3.4 Map	3	935.5	UniSTS
Cytogenetic Map	1	q21	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039081861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063266405	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC118914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC120811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC089987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000057177 ⟹ ENSRNOP00000054004

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	82,821,876 - 82,844,072 (-)	Ensembl
Rnor_6.0 Ensembl	1	84,339,261 - 84,353,725 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102599 ⟹ ENSRNOP00000080374

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	82,821,875 - 82,833,639 (-)	Ensembl

RefSeq Acc Id:

NM_001012167 ⟹ NP_001012167

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	91,949,465 - 91,961,207 (-)	NCBI
mRatBN7.2	1	82,821,865 - 82,833,607 (-)	NCBI
Rnor_6.0	1	84,339,271 - 84,351,013 (-)	NCBI
Rnor_5.0	1	85,556,092 - 85,578,621 (-)	NCBI
RGSC_v3.4	1	82,612,833 - 82,624,575 (-)	RGD
Celera	1	77,234,697 - 77,246,439 (-)	RGD

Sequence:

show sequence

GTAAGACCGGTGTCGTTTTAGGTCCCTGACACACCCACCTTGCCGCCTCCGTTCTGCAGAGGCC
CCCAGCTGCCAGGCAATATGAAGCCTAAACTGATGTACCAGGAGCTGAAGGTTCCTGTTGAGGA
ACCTGCGGGAGAACTGCCCATGAATGAAATCGAGGCATGGAAGGCAGCAGAGAAGAAAGCCCGT
TGGGTCCTCCTTGTCCTTATCCTGGCGGTAGTGGGCTTCGGTGCCCTGATGACTCAGCTGTTTC
TATGGGAATACGGGGACTTACATCTATTTGGCCCGAATCAGCACCCAGCCCCCTGCTATGACCC
CTGCGAGGCGGTGCTGGTGGAGAGCATTCCCGAGGGGCTGGAGTTTCCCAATGCCACCACAAGC
AACCCCTCCACCAGCCAGGCCTGGTTGGGCCTCCTTGCCGGTGCTCACAGCAGCCTGGACATCG
CGTCCTTCTACTGGACTCTCACAAACAATGATACCCACACGCAAGAGCCCTCTGCCCAGCAGGG
TGAAGAGGTTCTTCAGCAGCTTCAGGCTCTGGCACCTCGAGGTGTAAAGGTTCGCATCGCTGTG
AGCAAACCCAACGGACCTCTGGCTGATCTGCAGTCTCTGCTACAGAGTGGTGCCCAGGTGCGCA
TGGTGGACATGCAGAAGCTGACCCATGGTGTCCTGCACACCAAGTTCTGGGTGGTGGACCAGAC
CCACTTTTACCTGGGCAGTGCCAACATGGACTGGCGATCGCTGACCCAGGTCAAGGAGCTGGGC
GTGGTCATGTACAACTGCAGCTGCCTGGCTCGCGACCTCACCAAGATTTTTGAAGCCTATTGGT
TCCTGGGCCAGGCAGGCAGCTCCATCCCTTCAACCTGGCCACGGCCCTTTGACACCCGGTACAA
CCAAGAAACACCGATGGAGATCTGCCTCAATGGCACCCCAGCCCTGGCCTACCTGGCGAGTGCA
CCCCCGCCACTGTGTCCAGGTGGCCGCACCCCAGACCTGAAGGCACTGCTCAGCGTGGTGGACA
ACGCCCGAAGCTTCATCTACATTGCAGTTATGAACTACCTGCCCACCATGGAGTTCTCCCATCC
ACGCAGGTTCTGGCCAGCGATTGATGATGGGCTAAGACGGGCTGCGTATGAACGAGGCGTCAAA
GTGCGTTTGCTCATCAGCTGCTGGGGACACTCCGAGCCATCCATGCGGTCCTTCCTGCTCTCCC
TGGCTGCCCTTCGTGACAACCATACCCACTCTGACATCCAGGTGAAACTGTTTGTGGTCCCTGC
GGATGAGGCCCAAGCTCGAATCCCCTATGCCCGCGTCAACCACAACAAGTACATGGTGACTGAA
CGCACCACATACATTGGAACCTCCAACTGGTCTGGAAGCTACTTCACAGAGACGGCAGGCACCT
CCCTGCTGGTGACACAGAACGGGCACGGTGGCTTGCGCAGCCAGCTGGAGGCTGTTTTCCTGAG
AGACTGGGAATCCCCATACAGCCACAACCTTGACACCTCAGCCGACAGTGTGGGCAATGCCTGC
CGCCTGCTTTGAGGCTCATCTCGATGGACAGGCCAAAGCCTTCTGGGCCCCCCTGGACTCAGCA
CTGGGTCCTGGTTGCTGTCCCTGTGCCCTTGCTTCTGTCTATCCCATTGTGGCTCTGTACTCTC
TACTACACTCCTGTGGCTACCTCCACCTCCACTGGTCTGACACTCTGGCCCCTGTGGACTTAGC
AGAGCTGAGGGAGGATCGGGCCCCAAAGAAGTGGGGGTGCATGCTGGGCCCAGACCTTTGGCCC
ACCCCACAAAGGGGCCAAGATTATAAGTAAATAATTGTCTGTATAGCCTGTGCTAAAAAAAAAA
AAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006228578 ⟹ XP_006228640

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	91,949,465 - 91,971,834 (-)	NCBI
mRatBN7.2	1	82,821,863 - 82,844,214 (-)	NCBI
Rnor_6.0	1	84,339,269 - 84,361,648 (-)	NCBI
Rnor_5.0	1	85,556,092 - 85,578,621 (-)	NCBI

Sequence:

show sequence

ACCAGATGGGGGGAGCGAGGGCGATGGCCGTCACGTGACAACACGCAGCCTCCCAAGCCCCTGT
CCGCCCCAAGCTACACCGCGTTCGCGAAGAACGCCGCCAATCAGAAACGATCAGGTCTAGCCTT
TGCCCTGCCCGCAGTCTAACGCGAATGCGCCTGCGCACAGGTGGGCAGGAAGGCGGGGCTAGGT
TCTGGAGTAGAAGACTGTGACGTGCAGACTGTGATGTCTCACCTGGATACAGACAGGACCACAG
GCTAAGGAACTGGGAGCTGTTCTGTGGACAGGAAGAAGGTTACTCAGGACCACCCCTTCCCCTG
TTGCGGGGAGTCAGCCGACGACGTGCACACTGCGCAGACGCCTCGCTGCAGTGGGCGTGATCCG
TGGAGGTCCCGCCCCTTCTTTCCTCCCGCCCCTACTCAGCTGCTCAGGCAGAAGCTGGGGCCCC
ACCGAAGTAGCAGCCAACGTCGGAGTAAGACCGGTGTCGTTTTAGGTCCCTGACACACCCACCT
TGCCGCCTCCGTTCTGCAGAGGCCCCCAGCTGCCAGGCAATATGAAGCCTAAACTGATGTACCA
GGAGCTGAAGGTTCCTGTTGAGGAACCTGCGGGAGAACTGCCCATGAATGAAATCGAGGCATGG
AAGGCAGCAGAGAAGAAAGCCCGTTGGGTCCTCCTTGTCCTTATCCTGGCGGTAGTGGGCTTCG
GTGCCCTGATGACTCAGCTGTTTCTATGGGAATACGGGGACTTACATCTATTTGGCCCGAATCA
GCACCCAGCCCCCTGCTATGACCCCTGCGAGGCGGTGCTGGTGGAGAGCATTCCCGAGGGGCTG
GAGTTTCCCAATGCCACCACAAGCAACCCCTCCACCAGCCAGGCCTGGTTGGGCCTCCTTGCCG
GTGCTCACAGCAGCCTGGACATCGCGTCCTTCTACTGGACTCTCACAAACAATGATACCCACAC
GCAAGAGCCCTCTGCCCAGCAGGGTGAAGAGGTTCTTCAGCAGCTTCAGGCTCTGGCACCTCGA
GGTGTAAAGGTTCGCATCGCTGTGAGCAAACCCAACGGACCTCTGGCTGATCTGCAGTCTCTGC
TACAGAGTGGTGCCCAGGTGCGCATGGTGGACATGCAGAAGCTGACCCATGGTGTCCTGCACAC
CAAGTTCTGGGTGGTGGACCAGACCCACTTTTACCTGGGCAGTGCCAACATGGACTGGCGATCG
CTGACCCAGGTCAAGGAGCTGGGCGTGGTCATGTACAACTGCAGCTGCCTGGCTCGCGACCTCA
CCAAGATTTTTGAAGCCTATTGGTTCCTGGGCCAGGCAGGCAGCTCCATCCCTTCAACCTGGCC
ACGGCCCTTTGACACCCGGTACAACCAAGAAACACCGATGGAGATCTGCCTCAATGGCACCCCA
GCCCTGGCCTACCTGGCGAGTGCACCCCCGCCACTGTGTCCAGGTGGCCGCACCCCAGACCTGA
AGGCACTGCTCAGCGTGGTGGACAACGCCCGAAGCTTCATCTACATTGCAGTTATGAACTACCT
GCCCACCATGGAGTTCTCCCATCCACGCAGGTTCTGGCCAGCGATTGATGATGGGCTAAGACGG
GCTGCGTATGAACGAGGCGTCAAAGTGCGTTTGCTCATCAGCTGCTGGGGACACTCCGAGCCAT
CCATGCGGTCCTTCCTGCTCTCCCTGGCTGCCCTTCGTGACAACCATACCCACTCTGACATCCA
GGTGAAACTGTTTGTGGTCCCTGCGGATGAGGCCCAAGCTCGAATCCCCTATGCCCGCGTCAAC
CACAACAAGTACATGGTGACTGAACGCACCACATACATTGGAACCTCCAACTGGTCTGGAAGCT
ACTTCACAGAGACGGCAGGCACCTCCCTGCTGGTGACACAGAACGGGCACGGTGGCTTGCGCAG
CCAGCTGGAGGCTGTTTTCCTGAGAGACTGGGAATCCCCATACAGCCACAACCTTGACACCTCA
GCCGACAGTGTGGGCAATGCCTGCCGCCTGCTTTGAGGCTCATCTCGATGGACAGGCCAAAGCC
TTCTGGGCCCCCCTGGACTCAGCACTGGGTCCTGGTTGCTGTCCCTGTGCCCTTGCTTCTGTCT
ATCCCATTGTGGCTCTGTACTCTCTACTACACTCCTGTGGCTACCTCCACCTCCACTGGTCTGA
CACTCTGGCCCCTGTGGACTTAGCAGAGCTGAGGGAGGATCGGGCCCCAAAGAAGTGGGGGTGC
ATGCTGGGCCCAGACCTTTGGCCCACCCCACAAAGGGGCCAAGATTATAAGTAAATAATTGTCT
GTATAGCCTGTGCTAAGA

hide sequence

RefSeq Acc Id:

XM_006228580 ⟹ XP_006228642

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	91,949,465 - 91,971,762 (-)	NCBI
mRatBN7.2	1	82,821,863 - 82,844,280 (-)	NCBI
Rnor_6.0	1	84,339,269 - 84,361,686 (-)	NCBI
Rnor_5.0	1	85,556,092 - 85,578,621 (-)	NCBI

Sequence:

show sequence

AACCTCTCCCCCCGCCACTCTAATCCTCCTAGCCGCCAACCAGATGGGGGGAGCGAGGGCGATG
GCCGTCACGTGACAACACGCAGCCTCCCAAGCCCCTGTCCGCCCCAAGCTACACCGCGTTCGCG
AAGAACGCCGCCAATCAGAAACGATCAGGTCTAGCCTTTGCCCTGCCCGCAGTCTAACGCGAAT
GCGCCTGCGCACAGGTGGGCAGGAAGGCGGGGCTAGGTTCTGGAGTAGAAGACTGTGACGTGCA
GGTTACTCAGGACCACCCCTTCCCCTGTTGCGGGGAGTCAGCCGACGACGTGCACACTGCGCAG
ACGCCTCGCTGCAGTGGGCGTGATCCGTGGAGGTCCCGCCCCTTCTTTCCTCCCGCCCCTACTC
AGCTGCTCAGGCAGAAGCTGGGGCCCCACCGAAGTAGCAGCCAACGTCGGAGTAAGACCGGTGT
CGTTTTAGGTCCCTGACACACCCACCTTGCCGCCTCCGTTCTGCAGAGGCCCCCAGCTGCCAGG
CAATATGAAGCCTAAACTGATGTACCAGGAGCTGAAGGTTCCTGTTGAGGAACCTGCGGGAGAA
CTGCCCATGAATGAAATCGAGGCATGGAAGGCAGCAGAGAAGAAAGCCCGTTGGGTCCTCCTTG
TCCTTATCCTGGCGGTAGTGGGCTTCGGTGCCCTGATGACTCAGCTGTTTCTATGGGAATACGG
GGACTTACATCTATTTGGCCCGAATCAGCACCCAGCCCCCTGCTATGACCCCTGCGAGGCGGTG
CTGGTGGAGAGCATTCCCGAGGGGCTGGAGTTTCCCAATGCCACCACAAGCAACCCCTCCACCA
GCCAGGCCTGGTTGGGCCTCCTTGCCGGTGCTCACAGCAGCCTGGACATCGCGTCCTTCTACTG
GACTCTCACAAACAATGATACCCACACGCAAGAGCCCTCTGCCCAGCAGGGTGAAGAGGTTCTT
CAGCAGCTTCAGGCTCTGGCACCTCGAGGTGTAAAGGTTCGCATCGCTGTGAGCAAACCCAACG
GACCTCTGGCTGATCTGCAGTCTCTGCTACAGAGTGGTGCCCAGGTGCGCATGGTGGACATGCA
GAAGCTGACCCATGGTGTCCTGCACACCAAGTTCTGGGTGGTGGACCAGACCCACTTTTACCTG
GGCAGTGCCAACATGGACTGGCGATCGCTGACCCAGGTCAAGGAGCTGGGCGTGGTCATGTACA
ACTGCAGCTGCCTGGCTCGCGACCTCACCAAGATTTTTGAAGCCTATTGGTTCCTGGGCCAGGC
AGGCAGCTCCATCCCTTCAACCTGGCCACGGCCCTTTGACACCCGGTACAACCAAGAAACACCG
ATGGAGATCTGCCTCAATGGCACCCCAGCCCTGGCCTACCTGGCGAGTGCACCCCCGCCACTGT
GTCCAGGTGGCCGCACCCCAGACCTGAAGGCACTGCTCAGCGTGGTGGACAACGCCCGAAGCTT
CATCTACATTGCAGTTATGAACTACCTGCCCACCATGGAGTTCTCCCATCCACGCAGGTTCTGG
CCAGCGATTGATGATGGGCTAAGACGGGCTGCGTATGAACGAGGCGTCAAAGTGCGTTTGCTCA
TCAGCTGCTGGGGACACTCCGAGCCATCCATGCGGTCCTTCCTGCTCTCCCTGGCTGCCCTTCG
TGACAACCATACCCACTCTGACATCCAGGTGAAACTGTTTGTGGTCCCTGCGGATGAGGCCCAA
GCTCGAATCCCCTATGCCCGCGTCAACCACAACAAGTACATGGTGACTGAACGCACCACATACA
TTGGAACCTCCAACTGGTCTGGAAGCTACTTCACAGAGACGGCAGGCACCTCCCTGCTGGTGAC
ACAGAACGGGCACGGTGGCTTGCGCAGCCAGCTGGAGGCTGTTTTCCTGAGAGACTGGGAATCC
CCATACAGCCACAACCTTGACACCTCAGCCGACAGTGTGGGCAATGCCTGCCGCCTGCTTTGAG
GCTCATCTCGATGGACAGGCCAAAGCCTTCTGGGCCCCCCTGGACTCAGCACTGGGTCCTGGTT
GCTGTCCCTGTGCCCTTGCTTCTGTCTATCCCATTGTGGCTCTGTACTCTCTACTACACTCCTG
TGGCTACCTCCACCTCCACTGGTCTGACACTCTGGCCCCTGTGGACTTAGCAGAGCTGAGGGAG
GATCGGGCCCCAAAGAAGTGGGGGTGCATGCTGGGCCCAGACCTTTGGCCCACCCCACAAAGGG
GCCAAGATTATAAGTAAATAATTGTCTGTATAGCCTGTGCTAAGA

hide sequence

RefSeq Acc Id:

XM_006228581 ⟹ XP_006228643

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	91,949,465 - 91,971,763 (-)	NCBI
mRatBN7.2	1	82,821,863 - 82,844,238 (-)	NCBI
Rnor_6.0	1	84,339,269 - 84,361,648 (-)	NCBI
Rnor_5.0	1	85,556,092 - 85,578,621 (-)	NCBI

Sequence:

show sequence

ACCAGATGGGGGGAGCGAGGGCGATGGCCGTCACGTGACAACACGCAGCCTCCCAAGCCCCTGT
CCGCCCCAAGCTACACCGCGTTCGCGAAGAACGCCGCCAATCAGAAACGATCAGGTCTAGCCTT
TGCCCTGCCCGCAGTCTAACGCGAATGCGCCTGCGCACAGGTGGGCAGGAAGGCGGGGCTAGGT
TCTGGAGTAGAAGACTGTGACGTGCAGACTGTGATGTCTCACCTGGATACAGACAGGACCACAG
GCTAAGGAACTGGGAGCTGTTCTGTGGACAGGAAGAAGGTTACTCAGGACCACCCCTTCCCCTG
TTGCGGGGAGTCAGCCGACGACGTGCACACTGCGCAGACGCCTCGCTGCAGTGGGCGTGATCCG
TGGAGGTCCCGCCCCTTCTTTCCTCCCGCCCCTACTCAGCTGCTCAGGCAGAAGCTGGGGCCCC
ACCGAAGTAGCAGCCAACGTCGGATCCCTGACACACCCACCTTGCCGCCTCCGTTCTGCAGAGG
CCCCCAGCTGCCAGGCAATATGAAGCCTAAACTGATGTACCAGGAGCTGAAGGTTCCTGTTGAG
GAACCTGCGGGAGAACTGCCCATGAATGAAATCGAGGCATGGAAGGCAGCAGAGAAGAAAGCCC
GTTGGGTCCTCCTTGTCCTTATCCTGGCGGTAGTGGGCTTCGGTGCCCTGATGACTCAGCTGTT
TCTATGGGAATACGGGGACTTACATCTATTTGGCCCGAATCAGCACCCAGCCCCCTGCTATGAC
CCCTGCGAGGCGGTGCTGGTGGAGAGCATTCCCGAGGGGCTGGAGTTTCCCAATGCCACCACAA
GCAACCCCTCCACCAGCCAGGCCTGGTTGGGCCTCCTTGCCGGTGCTCACAGCAGCCTGGACAT
CGCGTCCTTCTACTGGACTCTCACAAACAATGATACCCACACGCAAGAGCCCTCTGCCCAGCAG
GGTGAAGAGGTTCTTCAGCAGCTTCAGGCTCTGGCACCTCGAGGTGTAAAGGTTCGCATCGCTG
TGAGCAAACCCAACGGACCTCTGGCTGATCTGCAGTCTCTGCTACAGAGTGGTGCCCAGGTGCG
CATGGTGGACATGCAGAAGCTGACCCATGGTGTCCTGCACACCAAGTTCTGGGTGGTGGACCAG
ACCCACTTTTACCTGGGCAGTGCCAACATGGACTGGCGATCGCTGACCCAGGTCAAGGAGCTGG
GCGTGGTCATGTACAACTGCAGCTGCCTGGCTCGCGACCTCACCAAGATTTTTGAAGCCTATTG
GTTCCTGGGCCAGGCAGGCAGCTCCATCCCTTCAACCTGGCCACGGCCCTTTGACACCCGGTAC
AACCAAGAAACACCGATGGAGATCTGCCTCAATGGCACCCCAGCCCTGGCCTACCTGGCGAGTG
CACCCCCGCCACTGTGTCCAGGTGGCCGCACCCCAGACCTGAAGGCACTGCTCAGCGTGGTGGA
CAACGCCCGAAGCTTCATCTACATTGCAGTTATGAACTACCTGCCCACCATGGAGTTCTCCCAT
CCACGCAGGTTCTGGCCAGCGATTGATGATGGGCTAAGACGGGCTGCGTATGAACGAGGCGTCA
AAGTGCGTTTGCTCATCAGCTGCTGGGGACACTCCGAGCCATCCATGCGGTCCTTCCTGCTCTC
CCTGGCTGCCCTTCGTGACAACCATACCCACTCTGACATCCAGGTGAAACTGTTTGTGGTCCCT
GCGGATGAGGCCCAAGCTCGAATCCCCTATGCCCGCGTCAACCACAACAAGTACATGGTGACTG
AACGCACCACATACATTGGAACCTCCAACTGGTCTGGAAGCTACTTCACAGAGACGGCAGGCAC
CTCCCTGCTGGTGACACAGAACGGGCACGGTGGCTTGCGCAGCCAGCTGGAGGCTGTTTTCCTG
AGAGACTGGGAATCCCCATACAGCCACAACCTTGACACCTCAGCCGACAGTGTGGGCAATGCCT
GCCGCCTGCTTTGAGGCTCATCTCGATGGACAGGCCAAAGCCTTCTGGGCCCCCCTGGACTCAG
CACTGGGTCCTGGTTGCTGTCCCTGTGCCCTTGCTTCTGTCTATCCCATTGTGGCTCTGTACTC
TCTACTACACTCCTGTGGCTACCTCCACCTCCACTGGTCTGACACTCTGGCCCCTGTGGACTTA
GCAGAGCTGAGGGAGGATCGGGCCCCAAAGAAGTGGGGGTGCATGCTGGGCCCAGACCTTTGGC
CCACCCCACAAAGGGGCCAAGATTATAAGTAAATAATTGTCTGTATAGCCTGTGCTAAGA

hide sequence

RefSeq Acc Id:

XM_039081861 ⟹ XP_038937789

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	91,949,465 - 91,971,763 (-)	NCBI
mRatBN7.2	1	82,821,863 - 82,844,215 (-)	NCBI

RefSeq Acc Id:

XM_063266400 ⟹ XP_063122470

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	91,949,465 - 91,971,805 (-)	NCBI

RefSeq Acc Id:

XM_063266405 ⟹ XP_063122475

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	91,949,465 - 91,971,762 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001012167	(Get FASTA)	NCBI Sequence Viewer
	XP_006228640	(Get FASTA)	NCBI Sequence Viewer
	XP_006228642	(Get FASTA)	NCBI Sequence Viewer
	XP_006228643	(Get FASTA)	NCBI Sequence Viewer
	XP_038937789	(Get FASTA)	NCBI Sequence Viewer
	XP_063122470	(Get FASTA)	NCBI Sequence Viewer
	XP_063122475	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH89987	(Get FASTA)	NCBI Sequence Viewer
	EDM07948	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000054004
	ENSRNOP00000054004.2
	ENSRNOP00000080374.1
GenBank Protein	Q5FVH2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001012167 ⟸ NM_001012167

- UniProtKB:

Q5FVH2 (UniProtKB/Swiss-Prot), A6J9D6 (UniProtKB/TrEMBL), A0A8I5ZPG5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKPKLMYQELKVPVEEPAGELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGD
LHLFGPNQHPAPCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWT
LTNNDTHTQEPSAQQGEEVLQQLQALAPRGVKVRIAVSKPNGPLADLQSLLQSGAQVRMVDMQK
LTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAG
SSIPSTWPRPFDTRYNQETPMEICLNGTPALAYLASAPPPLCPGGRTPDLKALLSVVDNARSFI
YIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSEPSMRSFLLSLAALRD
NHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERTTYIGTSNWSGSYFTETAGTSLLVTQ
NGHGGLRSQLEAVFLRDWESPYSHNLDTSADSVGNACRLL

hide sequence

RefSeq Acc Id:	XP_006228642 ⟸ XM_006228580
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVH2 (UniProtKB/Swiss-Prot), A6J9D6 (UniProtKB/TrEMBL), A0A8I5ZPG5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKPKLMYQELKVPVEEPAGELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGD LHLFGPNQHPAPCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWT LTNNDTHTQEPSAQQGEEVLQQLQALAPRGVKVRIAVSKPNGPLADLQSLLQSGAQVRMVDMQK LTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAG SSIPSTWPRPFDTRYNQETPMEICLNGTPALAYLASAPPPLCPGGRTPDLKALLSVVDNARSFI YIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSEPSMRSFLLSLAALRD NHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERTTYIGTSNWSGSYFTETAGTSLLVTQ NGHGGLRSQLEAVFLRDWESPYSHNLDTSADSVGNACRLL hide sequence

RefSeq Acc Id:	XP_006228643 ⟸ XM_006228581
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVH2 (UniProtKB/Swiss-Prot), A6J9D6 (UniProtKB/TrEMBL), A0A8I5ZPG5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKPKLMYQELKVPVEEPAGELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGD LHLFGPNQHPAPCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWT LTNNDTHTQEPSAQQGEEVLQQLQALAPRGVKVRIAVSKPNGPLADLQSLLQSGAQVRMVDMQK LTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAG SSIPSTWPRPFDTRYNQETPMEICLNGTPALAYLASAPPPLCPGGRTPDLKALLSVVDNARSFI YIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSEPSMRSFLLSLAALRD NHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERTTYIGTSNWSGSYFTETAGTSLLVTQ NGHGGLRSQLEAVFLRDWESPYSHNLDTSADSVGNACRLL hide sequence

RefSeq Acc Id:	XP_006228640 ⟸ XM_006228578
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVH2 (UniProtKB/Swiss-Prot), A6J9D6 (UniProtKB/TrEMBL), A0A8I5ZPG5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKPKLMYQELKVPVEEPAGELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGD LHLFGPNQHPAPCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWT LTNNDTHTQEPSAQQGEEVLQQLQALAPRGVKVRIAVSKPNGPLADLQSLLQSGAQVRMVDMQK LTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAG SSIPSTWPRPFDTRYNQETPMEICLNGTPALAYLASAPPPLCPGGRTPDLKALLSVVDNARSFI YIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSEPSMRSFLLSLAALRD NHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERTTYIGTSNWSGSYFTETAGTSLLVTQ NGHGGLRSQLEAVFLRDWESPYSHNLDTSADSVGNACRLL hide sequence

Ensembl Acc Id:

ENSRNOP00000054004 ⟸ ENSRNOT00000057177

RefSeq Acc Id:	XP_038937789 ⟸ XM_039081861
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVH2 (UniProtKB/Swiss-Prot), A6J9D6 (UniProtKB/TrEMBL), A0A8I5ZPG5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000080374 ⟸ ENSRNOT00000102599

RefSeq Acc Id:	XP_063122470 ⟸ XM_063266400
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVH2 (UniProtKB/Swiss-Prot), A0A8I5ZPG5 (UniProtKB/TrEMBL), A6J9D6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063122475 ⟸ XM_063266405
- Peptide Label:	isoform X1
- UniProtKB:	Q5FVH2 (UniProtKB/Swiss-Prot), A0A8I5ZPG5 (UniProtKB/TrEMBL), A6J9D6 (UniProtKB/TrEMBL)

Protein Domains

PLD phosphodiesterase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5FVH2-F1-model_v2	AlphaFold	Q5FVH2	1-488	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689855

Promoter ID:

EPDNEW_R380

Type:

initiation region

Name:

Pld3_1

Description:

phospholipase D family, member 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	84,351,052 - 84,351,112	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308248	AgrOrtholog
BioCyc Gene	G2FUF-60304	BioCyc
Ensembl Genes	ENSRNOG00000018390	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000057177	ENTREZGENE
	ENSRNOT00000057177.4	UniProtKB/Swiss-Prot
	ENSRNOT00000102599.1	UniProtKB/TrEMBL
Gene3D-CATH	Endonuclease Chain A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7318612	IMAGE-MGC_LOAD
InterPro	Diverse_PLD-related	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PLDc_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PLipase_D/transphosphatidylase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:361527	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:109410	IMAGE-MGC_LOAD
NCBI Gene	361527	ENTREZGENE
PANTHER	5'-3' EXONUCLEASE PLD3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PHOSPHOLIPASE D - RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	PLDc_3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Pld3	PhenoGen
PROSITE	PLD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000018390	RatGTEx
SMART	PLDc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Phospholipase D/nuclease	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZPG5	ENTREZGENE, UniProtKB/TrEMBL
	A6J9D6	ENTREZGENE, UniProtKB/TrEMBL
	PLD3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Pld3	phospholipase D family, member 3		phospholipase D3	Name updated	1299863	APPROVED
2005-12-06	Pld3	phospholipase D3	Pld3_predicted	phospholipase D3 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Pld3_predicted	phospholipase D3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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