Gtf2h1 (general transcription factor IIH subunit 1) - Rat Genome Database

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Gene: Gtf2h1 (general transcription factor IIH subunit 1) Rattus norvegicus
Analyze
Symbol: Gtf2h1
Name: general transcription factor IIH subunit 1
RGD ID: 1308225
Description: Enables chromatin binding activity. Involved in transcription by RNA polymerase II. Part of transcription factor TFIIH holo complex. Orthologous to human GTF2H1 (general transcription factor IIH subunit 1); PARTICIPATES IN nucleotide excision repair pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: general transcription factor II H, polypeptide 1; general transcription factor IIH, polypeptide 1; LOC361580
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81106,457,692 - 106,485,729 (+)NCBIGRCr8
GRCr8 Ensembl1106,457,394 - 106,485,727 (+)EnsemblGRCr8 Ensembl
mRatBN7.2197,321,417 - 97,349,455 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl197,321,394 - 97,349,455 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1102,713,646 - 102,741,801 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01111,185,630 - 111,213,785 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01104,469,761 - 104,497,796 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01102,849,618 - 102,877,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1102,849,889 - 102,877,944 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01103,923,681 - 103,951,995 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4197,352,251 - 97,380,298 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera191,568,224 - 91,596,262 (+)NCBICelera
RGSC_v3.1197,430,363 - 97,458,409 (+)NCBI
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
5-aza-2'-deoxycytidine  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aluminium sulfate (anhydrous)  (ISO)
Aroclor 1254  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (ISO)
bisphenol AF  (ISO)
cadmium dichloride  (EXP)
chromium(6+)  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
decabromodiphenyl ether  (EXP)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenthion  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
hydrogen peroxide  (ISO)
L-ascorbic acid  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
nitrates  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
phenylmercury acetate  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. TFIIH: when transcription met DNA repair. Compe E and Egly JM, Nat Rev Mol Cell Biol. 2012 May 10;13(6):343-54. doi: 10.1038/nrm3350.
2. The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding. Cowling VH and Cole MD, Mol Cell Biol. 2007 Mar;27(6):2059-73. Epub 2007 Jan 22.
3. A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor. Egly JM and Coin F, DNA Repair (Amst). 2011 Jul 15;10(7):714-21. doi: 10.1016/j.dnarep.2011.04.021. Epub 2011 May 17.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Ossipow V, etal., Cell. 1995 Oct 6;83(1):137-46.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tissue and cell distribution of a mammalian proteasomal ATPase, MSS1, and its complex formation with the basal transcription factors. Yanagi S, etal., Biochem Biophys Res Commun. 2000 Dec 20;279(2):568-73.
Additional References at PubMed
PMID:8692841   PMID:9852112   PMID:12815074   PMID:20439489  


Genomics

Comparative Map Data
Gtf2h1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81106,457,692 - 106,485,729 (+)NCBIGRCr8
GRCr8 Ensembl1106,457,394 - 106,485,727 (+)EnsemblGRCr8 Ensembl
mRatBN7.2197,321,417 - 97,349,455 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl197,321,394 - 97,349,455 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1102,713,646 - 102,741,801 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01111,185,630 - 111,213,785 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01104,469,761 - 104,497,796 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01102,849,618 - 102,877,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1102,849,889 - 102,877,944 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01103,923,681 - 103,951,995 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4197,352,251 - 97,380,298 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera191,568,224 - 91,596,262 (+)NCBICelera
RGSC_v3.1197,430,363 - 97,458,409 (+)NCBI
Cytogenetic Map1q22NCBI
GTF2H1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381118,322,567 - 18,367,045 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1118,322,295 - 18,367,045 (+)EnsemblGRCh38hg38GRCh38
GRCh371118,344,114 - 18,388,592 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361118,300,719 - 18,345,153 (+)NCBINCBI36Build 36hg18NCBI36
Build 341118,300,718 - 18,345,152NCBI
Celera1118,476,032 - 18,520,801 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1118,026,329 - 18,071,105 (+)NCBIHuRef
CHM1_11118,343,304 - 18,388,093 (+)NCBICHM1_1
T2T-CHM13v2.01118,418,103 - 18,462,582 (+)NCBIT2T-CHM13v2.0
Gtf2h1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39746,445,518 - 46,473,224 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl746,445,527 - 46,473,224 (+)EnsemblGRCm39 Ensembl
GRCm38746,796,094 - 46,823,800 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl746,796,103 - 46,823,800 (+)EnsemblGRCm38mm10GRCm38
MGSCv37754,051,464 - 54,079,170 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36746,664,145 - 46,691,839 (+)NCBIMGSCv36mm8
Celera742,274,479 - 42,302,829 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map730.58NCBI
Gtf2h1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541433,028,701 - 33,063,233 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541433,028,701 - 33,063,233 (+)NCBIChiLan1.0ChiLan1.0
GTF2H1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2920,636,598 - 20,681,276 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11120,596,985 - 20,641,633 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01118,357,594 - 18,402,268 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11118,042,822 - 18,086,898 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1118,042,824 - 18,086,898 (+)Ensemblpanpan1.1panPan2
GTF2H1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12140,770,661 - 40,807,329 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2140,770,983 - 40,806,556 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2140,250,242 - 40,286,596 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02141,894,288 - 41,930,625 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2141,894,288 - 41,930,623 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12140,886,602 - 40,922,934 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02141,075,253 - 41,111,663 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02141,452,829 - 41,489,189 (+)NCBIUU_Cfam_GSD_1.0
Gtf2h1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494744,869,445 - 44,906,096 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936528903,322 - 940,313 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936528903,429 - 940,308 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2H1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl240,857,723 - 40,900,624 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1240,857,720 - 40,900,591 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2243,921,524 - 43,964,052 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GTF2H1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1146,573,907 - 46,620,443 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl146,573,393 - 46,609,261 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038143,946,538 - 143,998,018 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf2h1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247669,808,170 - 9,848,173 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247669,807,973 - 9,848,167 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gtf2h1
303 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:402
Count of miRNA genes:225
Interacting mature miRNAs:270
Transcripts:ENSRNOT00000066791
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)187889942132889942Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)139728272132889942Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151941022208479811Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1102780511182384005Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)151940904168768703Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)192963855109494029Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1101228864146228864Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)187785026142582336Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183019780128019780Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)166404680111404680Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134184556172281316Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)166009857160501508Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134565911208798288Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)193903998191260518Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)166400974132889942Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)184107164115183752Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)191302413136302413Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)151511344153680016Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)1102359314153680016Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)199645382182701046Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)199645382221502378Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)186622262131622262Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)166077886111077886Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1103779152223964440Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)198879955208479939Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of, or within a discrete space in an open field apparatus (CMO:0001514)192683681137683681Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)152891222109116986Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)186993904131993904Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)187558587132558587Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)192683681137683681Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)197582336142582336Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1101594089146594089Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1100345976145345976Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)196717367160111531Rat

Markers in Region
BI293524  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2197,320,737 - 97,320,957 (+)MAPPERmRatBN7.2
Rnor_6.01102,849,223 - 102,849,442NCBIRnor6.0
Rnor_5.01103,923,286 - 103,923,505UniSTSRnor5.0
RGSC_v3.4197,351,585 - 97,351,804UniSTSRGSC3.4
Celera191,567,558 - 91,567,777UniSTS
RH 3.4 Map1909.5UniSTS
Cytogenetic Map1q22UniSTS
RH127470  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2197,349,108 - 97,349,313 (+)MAPPERmRatBN7.2
Rnor_6.01102,877,593 - 102,877,797NCBIRnor6.0
Rnor_5.01103,951,649 - 103,951,853UniSTSRnor5.0
RGSC_v3.4197,379,955 - 97,380,159UniSTSRGSC3.4
Celera191,595,919 - 91,596,123UniSTS
RH 3.4 Map1909.99UniSTS
Cytogenetic Map1q22UniSTS
RH140781  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2197,348,568 - 97,348,747 (+)MAPPERmRatBN7.2
Rnor_6.01102,877,053 - 102,877,231NCBIRnor6.0
Rnor_5.01103,951,109 - 103,951,287UniSTSRnor5.0
RGSC_v3.4197,379,415 - 97,379,593UniSTSRGSC3.4
Celera191,595,379 - 91,595,557UniSTS
RH 3.4 Map1908.6UniSTS
Cytogenetic Map1q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 11 49 113 91 90 59 25 59 6 218 97 11 93 45 60 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000066791   ⟹   ENSRNOP00000063357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1106,457,692 - 106,485,180 (+)Ensembl
mRatBN7.2 Ensembl197,321,404 - 97,349,452 (+)Ensembl
Rnor_6.0 Ensembl1102,849,889 - 102,877,936 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000087920   ⟹   ENSRNOP00000069965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1106,457,394 - 106,485,727 (+)Ensembl
mRatBN7.2 Ensembl197,321,394 - 97,349,455 (+)Ensembl
Rnor_6.0 Ensembl1102,857,251 - 102,877,944 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099036   ⟹   ENSRNOP00000095099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl197,329,696 - 97,349,450 (+)Ensembl
RefSeq Acc Id: NM_001399644   ⟹   NP_001386573
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81106,457,692 - 106,485,729 (+)NCBI
mRatBN7.2197,321,417 - 97,349,455 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001386573 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM07251 (Get FASTA)   NCBI Sequence Viewer  
  EDM07252 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000063357.1
  ENSRNOP00000069965
  ENSRNOP00000069965.2
  ENSRNOP00000095099.1
Ensembl Acc Id: ENSRNOP00000069965   ⟸   ENSRNOT00000087920
Ensembl Acc Id: ENSRNOP00000063357   ⟸   ENSRNOT00000066791
Ensembl Acc Id: ENSRNOP00000095099   ⟸   ENSRNOT00000099036
RefSeq Acc Id: NP_001386573   ⟸   NM_001399644
- UniProtKB: A6JBD2 (UniProtKB/TrEMBL),   D3ZYG3 (UniProtKB/TrEMBL)
Protein Domains
BSD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JWQ0-F1-model_v2 AlphaFold A0A0G2JWQ0 1-547 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690067
Promoter ID:EPDNEW_R591
Type:multiple initiation site
Name:Gtf2h1_1
Description:general transcription factor IIH subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01102,849,902 - 102,849,962EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308225 AgrOrtholog
BioCyc Gene G2FUF-59612 BioCyc
Ensembl Genes ENSRNOG00000012360 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066791.3 UniProtKB/TrEMBL
  ENSRNOT00000087920 ENTREZGENE
  ENSRNOT00000087920.2 UniProtKB/TrEMBL
  ENSRNOT00000099036.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.3970.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  6.10.140.1200 UniProtKB/TrEMBL
InterPro BSD UniProtKB/TrEMBL
  BSD_dom_sf UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Tfb1/p62 UniProtKB/TrEMBL
  TFIIH_BTF_p62_N UniProtKB/TrEMBL
NCBI Gene 361580 ENTREZGENE
PANTHER PTHR12856 UniProtKB/TrEMBL
Pfam BSD UniProtKB/TrEMBL
  TFIIH_BTF_p62_N UniProtKB/TrEMBL
PhenoGen Gtf2h1 PhenoGen
PROSITE BSD UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012360 RatGTEx
SMART BSD UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF140383 UniProtKB/TrEMBL
UniProt A0A0G2JWQ0_RAT UniProtKB/TrEMBL
  A0A8I6AJ08_RAT UniProtKB/TrEMBL
  A6JBD2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZYG3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-02 Gtf2h1  general transcription factor IIH subunit 1  Gtf2h1  general transcription factor IIH, polypeptide 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Gtf2h1  general transcription factor IIH, polypeptide 1  Gtf2h1  general transcription factor II H, polypeptide 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Gtf2h1  general transcription factor II H, polypeptide 1   Gtf2h1_predicted  general transcription factor II H, polypeptide 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Gtf2h1_predicted  general transcription factor II H, polypeptide 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED