Cytip (cytohesin 1 interacting protein) - Rat Genome Database

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Gene: Cytip (cytohesin 1 interacting protein) Rattus norvegicus
Analyze
Symbol: Cytip
Name: cytohesin 1 interacting protein
RGD ID: 1307990
Description: Predicted to be involved in regulation of cell adhesion. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cell cortex. Orthologous to human CYTIP (cytohesin 1 interacting protein); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: cytohesin-interacting protein; LOC311047; pleckstrin homology Sec7 and coiled-coil domain-binding protein; pleckstrin homology, Sec7 and coiled-coil domains, binding protein; Pscdbp
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8363,106,895 - 63,183,769 (-)NCBIGRCr8
mRatBN7.2342,698,058 - 42,774,955 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl342,698,768 - 42,725,993 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx346,030,208 - 46,057,446 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0354,626,568 - 54,653,798 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0352,405,369 - 52,432,599 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0344,150,494 - 44,225,723 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl344,150,992 - 44,177,689 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0349,269,641 - 49,344,787 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4339,893,884 - 39,921,114 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1339,790,260 - 39,817,486 (-)NCBI
Celera340,767,224 - 40,794,368 (-)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium hexachloroplatinate  (ISO)
antirheumatic drug  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (EXP,ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
butanal  (ISO)
cadmium dichloride  (EXP)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (ISO)
diuron  (ISO)
endosulfan  (EXP)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
glyphosate  (EXP)
imidacloprid  (EXP)
iron atom  (ISO)
iron(0)  (ISO)
kojic acid  (ISO)
L-methionine  (ISO)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pentanal  (ISO)
pirinixic acid  (ISO)
propanal  (ISO)
rotenone  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell cortex  (IBA,ISO)
cytoplasm  (ISO)
cytosol  (IEA,ISO)
early endosome  (IEA)
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:12606567   PMID:15489334  


Genomics

Comparative Map Data
Cytip
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8363,106,895 - 63,183,769 (-)NCBIGRCr8
mRatBN7.2342,698,058 - 42,774,955 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl342,698,768 - 42,725,993 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx346,030,208 - 46,057,446 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0354,626,568 - 54,653,798 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0352,405,369 - 52,432,599 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0344,150,494 - 44,225,723 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl344,150,992 - 44,177,689 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0349,269,641 - 49,344,787 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4339,893,884 - 39,921,114 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1339,790,260 - 39,817,486 (-)NCBI
Celera340,767,224 - 40,794,368 (-)NCBICelera
Cytogenetic Map3q21NCBI
CYTIP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382157,414,619 - 157,444,089 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2157,414,619 - 157,488,961 (-)EnsemblGRCh38hg38GRCh38
GRCh372158,271,131 - 158,300,601 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362157,979,377 - 158,008,850 (-)NCBINCBI36Build 36hg18NCBI36
Build 342158,096,639 - 158,126,112NCBI
Celera2151,884,278 - 151,913,751 (-)NCBICelera
Cytogenetic Map2q24.1NCBI
HuRef2150,156,652 - 150,186,277 (-)NCBIHuRef
CHM1_12158,277,149 - 158,306,602 (-)NCBICHM1_1
T2T-CHM13v2.02157,867,761 - 157,897,538 (-)NCBIT2T-CHM13v2.0
Cytip
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39258,019,151 - 58,085,559 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl258,019,149 - 58,085,544 (-)EnsemblGRCm39 Ensembl
GRCm38258,129,139 - 58,195,549 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl258,129,137 - 58,195,532 (-)EnsemblGRCm38mm10GRCm38
MGSCv37257,981,550 - 58,012,533 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36257,947,867 - 57,975,448 (-)NCBIMGSCv36mm8
Celera259,891,468 - 59,922,892 (-)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map233.05NCBI
Cytip
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544915,948,531 - 15,977,397 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544915,948,739 - 15,978,641 (+)NCBIChiLan1.0ChiLan1.0
CYTIP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21360,076,414 - 60,153,366 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B60,092,214 - 60,123,448 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B44,673,289 - 44,702,725 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B161,913,676 - 161,942,687 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B161,913,684 - 161,942,617 (-)Ensemblpanpan1.1panPan2
CYTIP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1363,429,407 - 3,501,992 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl363,431,934 - 3,503,140 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha363,566,361 - 3,639,265 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0363,551,505 - 3,624,462 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl363,551,505 - 3,625,315 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1363,553,796 - 3,627,461 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0363,613,492 - 3,686,312 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0363,651,516 - 3,724,409 (-)NCBIUU_Cfam_GSD_1.0
Cytip
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303120,556,416 - 120,586,884 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646921,034,015 - 21,063,704 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493646921,030,855 - 21,062,919 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYTIP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1564,353,475 - 64,382,152 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11564,353,146 - 64,421,306 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21571,188,262 - 71,214,530 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CYTIP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11042,823,176 - 42,902,194 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1042,822,776 - 42,902,171 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040156,676,252 - 156,753,529 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cytip
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247328,363,037 - 8,420,859 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247328,363,101 - 8,420,627 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cytip
277 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:61
Count of miRNA genes:49
Interacting mature miRNAs:60
Transcripts:ENSRNOT00000006387
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145447233430Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31831145447233430Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31831145447233430Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31831145447233430Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31831145447233430Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31831145447233430Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31831145447233430Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)32749462144188411Rat
2313049Bss72Bone structure and strength QTL 722.60.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)32749462150302886Rat
2313076Bss74Bone structure and strength QTL 7420.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)32749462150302886Rat
2313079Bss73Bone structure and strength QTL 731.5tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)32749462150302886Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)32749462150302886Rat
2313101Bmd76Bone mineral density QTL 763.60.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)32749462150302886Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
10450852Stl33Serum triglyceride level QTL 333.40.05blood LDL triglyceride amount (VT:0010699)blood lipoprotein triglyceride level (CMO:0002685)33819223350749747Rat
10450816Scl75Serum cholesterol level QTL 754.40.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33819223350749747Rat
10450813Scl74Serum cholesterol level QTL 745.80.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)33819223350749747Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
4889975Bmd81Bone mineral density QTL 814.3tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)33871036550302886Rat
634317Bw117Body weight QTL 1173.58abdominal fat pad mass (VT:1000711)abdominal fat pad weight to body weight ratio (CMO:0000095)33945463753296578Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat

Markers in Region
RH139985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2342,698,982 - 42,699,202 (+)MAPPERmRatBN7.2
Rnor_6.0344,151,207 - 44,151,426NCBIRnor6.0
Rnor_5.0349,270,354 - 49,270,573UniSTSRnor5.0
RGSC_v3.4339,894,108 - 39,894,327UniSTSRGSC3.4
Celera340,767,448 - 40,767,667UniSTS
RH 3.4 Map3555.5UniSTS
Cytogenetic Map3q21UniSTS
AU049310  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2342,716,167 - 42,716,323 (+)MAPPERmRatBN7.2
Rnor_6.0344,167,864 - 44,168,019NCBIRnor6.0
Rnor_5.0349,287,011 - 49,287,166UniSTSRnor5.0
RGSC_v3.4339,911,291 - 39,911,446UniSTSRGSC3.4
Celera340,784,626 - 40,784,781UniSTS
Cytogenetic Map3q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 8 19 13 14 11
Low 1 35 49 41 41 8 11 49 22 23 8
Below cutoff 8 25 4

Sequence


RefSeq Acc Id: ENSRNOT00000006387   ⟹   ENSRNOP00000006387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl342,698,768 - 42,725,993 (-)Ensembl
Rnor_6.0 Ensembl344,150,992 - 44,177,689 (-)Ensembl
RefSeq Acc Id: NM_001012086   ⟹   NP_001012086
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8363,107,598 - 63,134,832 (-)NCBI
mRatBN7.2342,698,759 - 42,725,993 (-)NCBI
Rnor_6.0344,150,983 - 44,177,689 (-)NCBI
Rnor_5.0349,269,641 - 49,344,787 (-)NCBI
RGSC_v3.4339,893,884 - 39,921,114 (-)RGD
Celera340,767,224 - 40,794,368 (-)RGD
Sequence:
RefSeq Acc Id: XM_006234202   ⟹   XP_006234264
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8363,106,895 - 63,183,769 (-)NCBI
mRatBN7.2342,698,058 - 42,774,955 (-)NCBI
Rnor_6.0344,150,494 - 44,225,723 (-)NCBI
Rnor_5.0349,269,641 - 49,344,787 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039104820   ⟹   XP_038960748
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8363,107,598 - 63,132,090 (-)NCBI
mRatBN7.2342,698,058 - 42,723,249 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001012086 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234264 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960748 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88207 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006387
  ENSRNOP00000006387.4
  ENSRNOP00055001022
  ENSRNOP00060009959
  ENSRNOP00065027819
GenBank Protein Q5I0L6 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001012086   ⟸   NM_001012086
- UniProtKB: Q5I0L6 (UniProtKB/Swiss-Prot),   A6JF54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234264   ⟸   XM_006234202
- Peptide Label: isoform X1
- UniProtKB: A6JF54 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006387   ⟸   ENSRNOT00000006387
RefSeq Acc Id: XP_038960748   ⟸   XM_039104820
- Peptide Label: isoform X2
Protein Domains
PDZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5I0L6-F1-model_v2 AlphaFold Q5I0L6 1-359 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692084
Promoter ID:EPDNEW_R2609
Type:multiple initiation site
Name:Cytip_1
Description:cytohesin 1 interacting protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0344,177,702 - 44,177,762EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307990 AgrOrtholog
BioCyc Gene G2FUF-49661 BioCyc
Ensembl Genes ENSRNOG00000004772 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055000741 UniProtKB/Swiss-Prot
  ENSRNOG00060007972 UniProtKB/Swiss-Prot
  ENSRNOG00065020505 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000006387 ENTREZGENE
  ENSRNOT00000006387.6 UniProtKB/Swiss-Prot
  ENSRNOT00055001274 UniProtKB/Swiss-Prot
  ENSRNOT00060013133 UniProtKB/Swiss-Prot
  ENSRNOT00065034674 UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7381695 IMAGE-MGC_LOAD
InterPro PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:311047 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108923 IMAGE-MGC_LOAD
NCBI Gene 311047 ENTREZGENE
PANTHER CYTOHESIN-INTERACTING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cytip PhenoGen
PROSITE PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004772 RatGTEx
  ENSRNOG00055000741 RatGTEx
  ENSRNOG00060007972 RatGTEx
  ENSRNOG00065020505 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PDZ domain-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6JF54 ENTREZGENE, UniProtKB/TrEMBL
  CYTIP_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-11-04 Cytip  cytohesin 1 interacting protein  Pscdbp  pleckstrin homology, Sec7 and coiled-coil domains, binding protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Pscdbp  pleckstrin homology, Sec7 and coiled-coil domains, binding protein  Pscdbp_predicted  pleckstrin homology, Sec7 and coiled-coil domains, binding protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Pscdbp_predicted  pleckstrin homology, Sec7 and coiled-coil domains, binding protein (predicted)      Symbol and Name status set to approved 70820 APPROVED