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Gene: Dennd1a (DENN domain containing 1A) Rattus norvegicus

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Symbol:

Dennd1a

Name:

DENN domain containing 1A

RGD ID:

1307927

Description:

Predicted to enable several functions, including SH3 domain binding activity; guanyl-nucleotide exchange factor activity; and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in several processes, including endocytic recycling; positive regulation of GTPase activity; and regulation of Rab protein signal transduction. Predicted to act upstream of or within synaptic vesicle endocytosis. Predicted to be located in several cellular components, including clathrin-coated vesicle membrane; dendrite; and neuronal cell body. Predicted to be active in clathrin-coated vesicle and cytosol. Orthologous to human DENND1A (DENN domain containing 1A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,5-hexanedione; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

DENN domain-containing protein 1A; DENN/MADD domain containing 1A; LOC311913; RGD1307927; similar to RIKEN cDNA 6030446I19 gene

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DENND1A (DENN domain containing 1A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Dennd1a (DENN domain containing 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dennd1a (DENN domain containing 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DENND1A (DENN domain containing 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DENND1A (DENN domain containing 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dennd1a (DENN domain containing 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DENND1A (DENN domain containing 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DENND1A (DENN domain containing 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dennd1a (DENN domain containing 1A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	DENND1A (DENN domain containing 1A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dennd1a (DENN domain containing 1A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dennd1a (DENN/MADD domain containing 1A)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG18659	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	rme-4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	41,974,502 - 42,461,816 (-)	NCBI		GRCr8
mRatBN7.2	3	21,564,749 - 22,052,057 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	21,564,749 - 22,052,062 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	25,032,954 - 25,463,774 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	33,617,912 - 34,048,766 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	31,429,892 - 31,860,523 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	22,061,120 - 22,501,502 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	22,058,400 - 22,500,765 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	27,296,829 - 27,750,936 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	17,561,878 - 17,996,342 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	17,459,291 - 17,993,186 (-)	NCBI
Celera	3	19,998,559 - 20,428,895 (-)	NCBI		Celera
Cytogenetic Map	3	q11-q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,5-hexanedione (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

caffeine (ISO)

CGP 52608 (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

coumestrol (ISO)

cytarabine (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

folic acid (ISO)

formaldehyde (ISO)

FR900359 (ISO)

fulvestrant (ISO)

gentamycin (EXP)

hypochlorous acid (ISO)

isobutanol (ISO)

leflunomide (ISO)

methapyrilene (ISO)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

N-methyl-4-phenylpyridinium (EXP)

nickel atom (ISO)

O-methyleugenol (ISO)

panobinostat (ISO)

perfluorohexanesulfonic acid (ISO)

permethrin (EXP)

phenylmercury acetate (ISO)

quercetin (ISO)

SB 431542 (ISO)

sodium dichromate (EXP)

sunitinib (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

Triptolide (EXP)

tungsten (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endocytic recycling (IBA,ISO)

endocytosis (IBA,ISO)

positive regulation of GTPase activity (ISO)

regulation of Rab protein signal transduction (ISO)

synaptic vesicle endocytosis (ISO)

Cellular Component

clathrin-coated vesicle (IBA,IEA,ISO)

clathrin-coated vesicle membrane (ISO)

cytoplasmic vesicle (IEA)

cytosol (IBA,ISO)

dendrite (ISO)

intracellular membrane-bounded organelle (ISO)

neuronal cell body (ISO)

presynapse (IEA)

synapse (ISO)

Molecular Function

guanyl-nucleotide exchange factor activity (IEA,ISO)

phosphatidylinositol phosphate binding (IBA,ISO)

phosphatidylinositol-3-phosphate binding (ISO)

protein binding (ISO)

SH3 domain binding (ISO)

small GTPase binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:17182770	PMID:17762867	PMID:20159556	PMID:20937701

Genomics

Comparative Map Data

Dennd1a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	41,974,502 - 42,461,816 (-)	NCBI		GRCr8
mRatBN7.2	3	21,564,749 - 22,052,057 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	21,564,749 - 22,052,062 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	25,032,954 - 25,463,774 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	33,617,912 - 34,048,766 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	31,429,892 - 31,860,523 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	22,061,120 - 22,501,502 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	22,058,400 - 22,500,765 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	27,296,829 - 27,750,936 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	17,561,878 - 17,996,342 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	17,459,291 - 17,993,186 (-)	NCBI
Celera	3	19,998,559 - 20,428,895 (-)	NCBI		Celera
Cytogenetic Map	3	q11-q12	NCBI

DENND1A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	123,379,658 - 123,930,126 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	123,379,654 - 123,930,152 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	126,141,937 - 126,692,405 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	125,181,754 - 125,732,238 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	123,243,423 - 123,771,971	NCBI
Celera	9	96,790,158 - 97,339,675 (-)	NCBI		Celera
Cytogenetic Map	9	q33.3	NCBI
HuRef	9	95,756,878 - 96,306,367 (-)	NCBI		HuRef
CHM1_1	9	126,290,596 - 126,841,219 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	135,577,391 - 136,128,012 (-)	NCBI		T2T-CHM13v2.0

Dennd1a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	37,689,002 - 38,177,417 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	37,689,003 - 38,177,402 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	37,798,990 - 38,287,410 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	37,798,991 - 38,287,390 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	37,654,510 - 38,142,904 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	37,621,000 - 38,109,356 (-)	NCBI		MGSCv36	mm8
Celera	2	37,484,305 - 37,845,059 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	24.19	NCBI

Dennd1a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	4,146,456 - 4,608,425 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	4,120,095 - 4,605,002 (+)	NCBI	ChiLan1.0	ChiLan1.0

DENND1A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	15,422,791 - 15,965,600 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	15,425,146 - 15,967,947 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	94,511,281 - 95,053,490 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	123,035,433 - 123,532,038 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	123,037,217 - 123,532,037 (-)	Ensembl	panpan1.1		panPan2

DENND1A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	58,918,699 - 59,424,685 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	58,919,265 - 59,424,684 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	58,114,217 - 58,621,184 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	59,835,883 - 60,345,684 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	59,835,961 - 60,345,010 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	58,595,059 - 59,104,298 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	58,911,773 - 59,419,867 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	59,002,954 - 59,512,277 (+)	NCBI		UU_Cfam_GSD_1.0

Dennd1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	192,046,518 - 192,564,066 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	11,812,658 - 12,332,673 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	11,815,040 - 12,332,603 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DENND1A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	264,300,994 - 264,823,489 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	264,300,989 - 264,823,351 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	298,049,860 - 298,440,397 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DENND1A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	14,211,743 - 14,756,063 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	14,212,606 - 14,758,953 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666079	1,313,817 - 1,856,832 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dennd1a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	11,043,348 - 11,575,531 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	11,043,099 - 11,576,600 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Dennd1a
1655 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	617
Count of miRNA genes:	261
Interacting mature miRNAs:	308
Transcripts:	ENSRNOT00000025443
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	8658162	27494778	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	17374703	35528639	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	8227194	33703538	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	10434306	24512004	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	15005422	76927699	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	33278763	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	33230976	Rat
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	18311454	47233430	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	18311454	47233430	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	18311454	47233430	Rat
10450804	Scl70	Serum cholesterol level QTL 70	4.7	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	20714090	65714090	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	10778823	30356773	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	18311454	47233430	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	10778704	50302886	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	18311454	47233430	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	18311454	47233430	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	18311454	47233430	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2325840	Bp345	Blood pressure QTL 345		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	18311454	28441896	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	16954708	61954708	Rat
10450794	Scl69	Serum cholesterol level QTL 69	6.3	0.001	blood LDL cholesterol amount (VT:0000181)	blood low density lipoprotein cholesterol level (CMO:0000053)	3	20714090	65714090	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	31158234	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	8658162	27494778	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	27494778	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat

Markers in Region

RH138437

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	21,564,590 - 21,564,746 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	22,060,962 - 22,061,117	NCBI	Rnor6.0
Rnor_5.0	3	27,296,671 - 27,296,826	UniSTS	Rnor5.0
RGSC_v3.4	3	17,561,720 - 17,561,875	UniSTS	RGSC3.4
Celera	3	19,998,401 - 19,998,556	UniSTS
RH 3.4 Map	3	209.1	UniSTS
Cytogenetic Map	3	q11	UniSTS

RH141980

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	21,649,351 - 21,649,538 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	22,145,785 - 22,145,971	NCBI	Rnor6.0
Rnor_5.0	3	27,380,964 - 27,381,150	UniSTS	Rnor5.0
RGSC_v3.4	3	17,647,664 - 17,647,850	UniSTS	RGSC3.4
Celera	3	20,083,063 - 20,083,249	UniSTS
RH 3.4 Map	3	189.1	UniSTS
Cytogenetic Map	3	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001434229	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761757	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591856	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591857	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105281	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105285	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105287	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105289	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105290	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283978	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283980	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283982	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166562	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473983	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000025443 ⟹ ENSRNOP00000025443

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	21,564,749 - 21,994,873 (-)	Ensembl
Rnor_6.0 Ensembl	3	22,061,126 - 22,500,765 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000091747 ⟹ ENSRNOP00000073834

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	21,564,749 - 21,955,055 (-)	Ensembl
Rnor_6.0 Ensembl	3	22,058,400 - 22,459,257 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000096396 ⟹ ENSRNOP00000088926

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	21,564,749 - 22,052,062 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097346 ⟹ ENSRNOP00000077456

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	21,564,749 - 22,052,062 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000108920 ⟹ ENSRNOP00000078866

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	21,564,749 - 21,955,055 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116730 ⟹ ENSRNOP00000094401

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	21,564,749 - 21,994,873 (-)	Ensembl

RefSeq Acc Id:

NM_001191747 ⟹ NP_001178676

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,502 - 42,404,603 (-)	NCBI
mRatBN7.2	3	21,564,749 - 21,994,873 (-)	NCBI
Rnor_6.0	3	22,061,120 - 22,500,765 (-)	NCBI
Rnor_5.0	3	27,296,829 - 27,750,936 (-)	NCBI
Celera	3	19,998,559 - 20,428,895 (-)	NCBI

Sequence:

show sequence

ATGATTTGTTTCCTTTGTAGACAAAACCCGGAGACTACATTTGAAGTGTATGTGGAAGTGGCCT
ATCCTAGGACAGGTGGCACGCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAG
TGACCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTTCCCTTCTATGTGGACAGCCTCTCA
GTTAGCCAAGTTGGCCAGAACTTCACATTTGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCCAAGAGCTGCTTCTGTATCTTAAGCTACCTCCCCTGGTT
TGAGGTATTTTATAAGCTCCTTAACATCTTGGCAGATTACACAACAAAACAACAGGAAAGTCAG
TGGAATGAACTTCTTGAAACTCTGCACAGACTTCCCATTCCAGACCCCGGAGTGTCTGTTCACC
TCAGCGTGCATTCTTACTTCACTGTGCCTGATAGCAGAGAGCTTCCCAGCATACCTGAGAATAG
AAATCTGACAGAATATTTTGTGGCTGTGGATGTGAACAACATGTTGCATCTGTACGCCAGCATG
CTGTATGAGCGCCGGATCCTCATCATCTGCAGCAAGCTGAGTACCTTGACGGCCTGCATCCACG
GCTCTGCTGCCATGCTCTACCCCATGTACTGGCAGCATGTGTACATCCCTGTGCTGCCCCCACA
TCTGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAG
AAGGTCAGAAACATGGCCCTAGATGATGTTGTGATCTTGAATGTGGACACCAACACCCTGGAAA
CCCCTTTTGATGACCTTCAGAGCCTCCCAAATGATGTGATCTCCTCCCTGAAGAACAGGCTGAA
GAAGGTCTCCACAACCACAGGCGATGGGGTGGCCAGAGCCTTCCTCAAGGCCCAGGCTGCTTTC
TTTGGCAGCTACCGGAATGCACTGAAAATTGAGCCAGAAGAACCCATCACTTTCAGTGAGGAGG
CCTTCGTGTCCCACTACCGCTCTGGAGCCATGAGACAGTTCCTACAGAATGCCACACAGTTGCA
GCTCTTCAAGCAGTTTATCGATGGCCGACTAGACCTTCTCAATTCCGGTGAAGGTTTCAGTGAT
GTCTTTGAGGAGGAGATCAGCATGGGAGAATATGCCGGCAGTGATAAACTGTACCATCAGTGGC
TGTCCACAGTCCGGAAAGGAAGTGGAGCGATTCTGAATACTGTAAAAACAAAAGCTAACCCAGC
CATGAAGACTGTCTACAAGTTTGCAAAAGATCATGCAAAAATGGGAATAAAAGAGGTGAAAAAC
CGCTTGAAGCAAAAGGACATCACCGAGAATGGCTGTGCATCCTCTGCAGAAGATCCACTGCCAA
AGACCATACCATCCCCACTGGCAGAGGCCAAGGACCCCAAACTTCGAGAAGACCGGAGACCAAT
CACAGTCCACTTTGGGCAGGTAAGACCGCCTCGGCCGCATGTCATCAAGAGACCCAAGAGCAAC
ATGGCTGTGGAAGGCCGGAGGACGTCCATCTCAAGCCCCGAGCAGCCACAGCCATACAGGACTT
TGAAAGAATCAGACAGCGCAGAAGGTGATGAGACCGAGAGTCCAGAGCAGCCAACTCGGGAGCC
CTGGGGGCCTACCCCTGCTCCACCTGACCGAGCTGCCAGCATTGACCTTCTAGAAGATGTCTTC
AGCAGCCTAGATGTGGAGGCACCACTGCAGCCGCTGGGCCAAGCCAAGAGCCTGGAGGATCTTC
GGGTCCCCAGAGACTTGCGGGAACAGTCAGGCAGCTTTGATTACCAGAGGCTGGACCTATGCAG
AAGTGAGAGGGGCCTTAGCATGGCTGCAGCCTTGAAGTTTGCTCATCCATATACTCAGCTCTGG
AGTCTCGGACAAGACGACATGGCCATCCCCAGCAAGCCCTCCATGACCTCCCCTGAGAAGCCCT
CAGCTCTGCTTGGTACTTTGCCAGCACTGCCTGTCAGACCCCAGAACCAGGAGGGCATCCTGAG
CCCCAGCATCAAGGAGGAGACTCCCGTGCCAGCTCCAGGCAGCATCACCATTCCCAGGCCACAA
GGCAGAAAGACCCCTGAGCTTGGCATTGTGCCTCCACCACCCACTGCCCGGCCAGCCAAGCTCC
AGGGTGCTGGCGGCCCACTTGGTGACTTCTCTTCAGAGCCACTACAGATGGACCTGGAAAGACA
AGCTGCTCTGAGTCCAGCCCTCTTGTCAGGGCTGCTCCCGAGAGCTGGTCCCCAAGGCTCCACA
GAACTTGTGCAGTCACCCAGCCCAGCCCCAGGAGCTGCAGGCACAGGCAGCGATGCCCTGCTTG
CTCTCCTGGACCCACTTAACACAGCCTGGTCAGGCAGCACCATCCCATCCTATCCTACTACCCC
CAGTGTAGCCACCCCATTCACCCCCCAGCTCAGCTTCCCCTCAACAGTGACACCCTCCCCTTTT
GCACAGACACCACTCAATCCCTTTGTCCCCTCTGTGCCAGTAGTACCACCCACCATGTCCCTGG
GCTCTACACCAGCCAGACCTTTTGGGACGCCTCCAGCATCCCTAGGGCCAGCATATGCACCTAG
CATCCTATTGTCTGGTTCTAGCTTCTGTGCCCCTCACAGGTCTCAGCCCACCCTCTCTGCTCTC
TCTATGCCCAACCTCTTTGGCCAGATCCCAATGGGTGCCCACACTAGTCCCCTGCAGCCACTTG
GCCCCCCAGCCGTTGCCCCCTCCAGGATCCGAACATTGCCTCTGCCCCGCTCAAGTGCCAGGGC
TGCTGAGGCCAAGCAGGGGTTGGCCCTGAGGCCAGGTGAATCCCCACTGCTGCCTCCTAGACCA
CCACAGAATCTACAGCCAACCCTGCAGCCCTCTGCTCCTACACAGGCCAGAGACCCCTTTGAGG
ATTTGCTACGGAAAACCAAGCAAGATGTGAGCCCAAGCCCAGTCCCGGCCCCGGCCCCAGCCCC
AGCCCCAGCCTCAGCCTCCACCTCTGTGGAGCAGCTCCGCAGGCAGTGGGAGACCTTCGAGTGA
CCATGCCTATGCCACTGTCCAGTACCGTGCCTCCCCAGTGTCCCGTTCCTGGCCAGGCTTCACC
GGGGCAAAGGGACTCTGCCCCTCTCCTCCATAGCCCATCTCTGAGGCCTGGCCCTGGGAGCTCG
TCCCAGAGGAGAGAGCTGCCTGCCACCACCCTCAGCACCCTGTGTGGGTTTTGCACTATATGTC
AGCTGGGCCAGCTGTGTCCCACCACCTTCCCTCCCTTAGTCCAAGAGGAGTCAAGAAGCTCGAG
GCTGCTCTCAAGCCCAGCTCTCCTCCTTTGCTGGGCCCTACCCCACAGGGCAGATGTCAGTAAC
GCACTGTGTAAGCACATCTTTGGGGGACATAGGTGTTTGGGGGGCTGGAATGAGGACCACTCCT
GGGCTGGCATTTCTCCCTGGTGGTCATCTCCAAACCTCACTAAGCAATACACTCTTTGCTGAGT
CTTCACCTAACCACCAAACTCGAGTTGTTCCTAAAGGGCCAGCGGTCTGGAGACCTAATGGTCA
ACAAGCCCAGCCCCAGCCAGCCCTTCCAGGGCTCGGGAACACCAGCAACTCTAATTTATACGAC
GACCCCCAAACCTGAGTCGAAGGAGCTGCCTTTAGCTCTGCCACCTCCATACCTCTGGGCTTTC
CTGTCAATCAAAGCTCAGGCTCAGCCTCCTGCCCATGGAGCTTATGGGCACCAGTGATGGAGTC
CAGCTCAAAGGACAAGCTTCCTGACACAGGCAAAAGAGAGGGCAGCTGCTTGAGCTCCTGGGTC
AAGATCAGGTGGGGCCCCAGGCCCCCAGGGGCCCCGTGGAGTGAATATACACATGGCCTCTGAG
CCTGGGGCGGGTGGGGCCCAGCCCTCCCCACTGTCTCCAGCCTCTCGCCAGCGCAGAAATTCCT
GAGTCCAAGTCACCAAAGTTATAATGAAATGTTTGTTATTGTTTCTTTGATCTTGCTTTTCCTT
TTTACCTTATTGATTTGATGAATCTTGAAAATTGATTCCTTTCAATAAACCAAGGTAAAACACA
GACTAACCATTTAAGAAA

hide sequence

RefSeq Acc Id:

XM_039105281 ⟹ XP_038961209

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,786 (-)	NCBI
mRatBN7.2	3	21,564,765 - 22,052,052 (-)	NCBI

RefSeq Acc Id:

XM_039105285 ⟹ XP_038961213

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,816 (-)	NCBI
mRatBN7.2	3	21,564,765 - 22,052,049 (-)	NCBI

RefSeq Acc Id:

XM_039105287 ⟹ XP_038961215

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,816 (-)	NCBI
mRatBN7.2	3	21,564,765 - 22,052,047 (-)	NCBI

RefSeq Acc Id:

XM_039105289 ⟹ XP_038961217

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,784 (-)	NCBI
mRatBN7.2	3	21,564,765 - 22,052,050 (-)	NCBI

RefSeq Acc Id:

XM_039105290 ⟹ XP_038961218

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,783 (-)	NCBI
mRatBN7.2	3	21,564,765 - 22,052,049 (-)	NCBI

RefSeq Acc Id:

XM_039105292 ⟹ XP_038961220

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,816 (-)	NCBI
mRatBN7.2	3	21,564,765 - 22,052,046 (-)	NCBI

RefSeq Acc Id:

XM_063283977 ⟹ XP_063140047

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,785 (-)	NCBI

RefSeq Acc Id:

XM_063283978 ⟹ XP_063140048

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,412,676 (-)	NCBI

RefSeq Acc Id:

XM_063283979 ⟹ XP_063140049

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,412,673 (-)	NCBI

RefSeq Acc Id:

XM_063283980 ⟹ XP_063140050

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,784 (-)	NCBI

RefSeq Acc Id:

XM_063283981 ⟹ XP_063140051

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,434,131 (-)	NCBI

RefSeq Acc Id:

XM_063283982 ⟹ XP_063140052

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,412,670 (-)	NCBI

RefSeq Acc Id:

XM_063283984 ⟹ XP_063140054

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,813 (-)	NCBI

RefSeq Acc Id:

XM_063283985 ⟹ XP_063140055

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,784 (-)	NCBI

RefSeq Acc Id:

XM_063283986 ⟹ XP_063140056

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,784 (-)	NCBI

RefSeq Acc Id:

XM_063283987 ⟹ XP_063140057

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,779 (-)	NCBI

RefSeq Acc Id:

XM_063283988 ⟹ XP_063140058

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,813 (-)	NCBI

RefSeq Acc Id:

XM_063283989 ⟹ XP_063140059

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,778 (-)	NCBI

RefSeq Acc Id:

XM_063283990 ⟹ XP_063140060

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,461,586 (-)	NCBI

RefSeq Acc Id:

XM_063283991 ⟹ XP_063140061

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,302,174 (-)	NCBI

RefSeq Acc Id:

XM_063283992 ⟹ XP_063140062

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,188,900 (-)	NCBI

RefSeq Acc Id:

XM_063283993 ⟹ XP_063140063

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,974,520 - 42,188,898 (-)	NCBI

RefSeq Acc Id:

XM_063283994 ⟹ XP_063140064

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	42,006,481 - 42,412,688 (-)	NCBI

RefSeq Acc Id:

XM_063283995 ⟹ XP_063140065

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	41,997,101 - 42,412,685 (-)	NCBI

RefSeq Acc Id:

XM_063283996 ⟹ XP_063140066

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	42,027,286 - 42,412,692 (-)	NCBI

RefSeq Acc Id:

XM_063283997 ⟹ XP_063140067

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	42,027,286 - 42,412,682 (-)	NCBI

RefSeq Acc Id:

XM_063283998 ⟹ XP_063140068

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	42,006,481 - 42,461,789 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178676	(Get FASTA)	NCBI Sequence Viewer
	NP_001421158	(Get FASTA)	NCBI Sequence Viewer
	XP_038961209	(Get FASTA)	NCBI Sequence Viewer
	XP_038961213	(Get FASTA)	NCBI Sequence Viewer
	XP_038961215	(Get FASTA)	NCBI Sequence Viewer
	XP_038961217	(Get FASTA)	NCBI Sequence Viewer
	XP_038961218	(Get FASTA)	NCBI Sequence Viewer
	XP_038961220	(Get FASTA)	NCBI Sequence Viewer
	XP_063140047	(Get FASTA)	NCBI Sequence Viewer
	XP_063140048	(Get FASTA)	NCBI Sequence Viewer
	XP_063140049	(Get FASTA)	NCBI Sequence Viewer
	XP_063140050	(Get FASTA)	NCBI Sequence Viewer
	XP_063140051	(Get FASTA)	NCBI Sequence Viewer
	XP_063140052	(Get FASTA)	NCBI Sequence Viewer
	XP_063140054	(Get FASTA)	NCBI Sequence Viewer
	XP_063140055	(Get FASTA)	NCBI Sequence Viewer
	XP_063140056	(Get FASTA)	NCBI Sequence Viewer
	XP_063140057	(Get FASTA)	NCBI Sequence Viewer
	XP_063140058	(Get FASTA)	NCBI Sequence Viewer
	XP_063140059	(Get FASTA)	NCBI Sequence Viewer
	XP_063140060	(Get FASTA)	NCBI Sequence Viewer
	XP_063140061	(Get FASTA)	NCBI Sequence Viewer
	XP_063140062	(Get FASTA)	NCBI Sequence Viewer
	XP_063140063	(Get FASTA)	NCBI Sequence Viewer
	XP_063140064	(Get FASTA)	NCBI Sequence Viewer
	XP_063140065	(Get FASTA)	NCBI Sequence Viewer
	XP_063140066	(Get FASTA)	NCBI Sequence Viewer
	XP_063140067	(Get FASTA)	NCBI Sequence Viewer
	XP_063140068	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66562	(Get FASTA)	NCBI Sequence Viewer
	EDM00519	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000025443
	ENSRNOP00000025443.5
	ENSRNOP00000073834.1
	ENSRNOP00000077456
	ENSRNOP00000077456.1
	ENSRNOP00000078866
	ENSRNOP00000078866.1
	ENSRNOP00000088926
	ENSRNOP00000088926.1
	ENSRNOP00000094401
	ENSRNOP00000094401.1
	ENSRNOP00000102796
	ENSRNOP00000105651

RefSeq Acc Id:

NP_001178676 ⟸ NM_001191747

- UniProtKB:

A0A8I6GKQ9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MICFLCRQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLS
VSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKQQESQ
WNELLETLHRLPIPDPGVSVHLSVHSYFTVPDSRELPSIPENRNLTEYFVAVDVNNMLHLYASM
LYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLME
KVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAF
FGSYRNALKIEPEEPITFSEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSD
VFEEEISMGEYAGSDKLYHQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKN
RLKQKDITENGCASSAEDPLPKTIPSPLAEAKDPKLREDRRPITVHFGQVRPPRPHVIKRPKSN
MAVEGRRTSISSPEQPQPYRTLKESDSAEGDETESPEQPTREPWGPTPAPPDRAASIDLLEDVF
SSLDVEAPLQPLGQAKSLEDLRVPRDLREQSGSFDYQRLDLCRSERGLSMAAALKFAHPYTQLW
SLGQDDMAIPSKPSMTSPEKPSALLGTLPALPVRPQNQEGILSPSIKEETPVPAPGSITIPRPQ
GRKTPELGIVPPPPTARPAKLQGAGGPLGDFSSEPLQMDLERQAALSPALLSGLLPRAGPQGST
ELVQSPSPAPGAAGTGSDALLALLDPLNTAWSGSTIPSYPTTPSVATPFTPQLSFPSTVTPSPF
AQTPLNPFVPSVPVVPPTMSLGSTPARPFGTPPASLGPAYAPSILLSGSSFCAPHRSQPTLSAL
SMPNLFGQIPMGAHTSPLQPLGPPAVAPSRIRTLPLPRSSARAAEAKQGLALRPGESPLLPPRP
PQNLQPTLQPSAPTQARDPFEDLLRKTKQDVSPSPVPAPAPAPAPASASTSVEQLRRQWETFE

hide sequence

Ensembl Acc Id:

ENSRNOP00000025443 ⟸ ENSRNOT00000025443

Ensembl Acc Id:

ENSRNOP00000073834 ⟸ ENSRNOT00000091747

RefSeq Acc Id:	XP_038961209 ⟸ XM_039105281
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961217 ⟸ XM_039105289
- Peptide Label:	isoform X10
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961218 ⟸ XM_039105290
- Peptide Label:	isoform X11
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961213 ⟸ XM_039105285
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961215 ⟸ XM_039105287
- Peptide Label:	isoform X8
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961220 ⟸ XM_039105292
- Peptide Label:	isoform X14
- UniProtKB:	A0A8I6GKQ9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000088926 ⟸ ENSRNOT00000096396

Ensembl Acc Id:

ENSRNOP00000077456 ⟸ ENSRNOT00000097346

Ensembl Acc Id:

ENSRNOP00000094401 ⟸ ENSRNOT00000116730

Ensembl Acc Id:

ENSRNOP00000078866 ⟸ ENSRNOT00000108920

RefSeq Acc Id:	XP_063140058 ⟸ XM_063283988
- Peptide Label:	isoform X17

RefSeq Acc Id:	XP_063140054 ⟸ XM_063283984
- Peptide Label:	isoform X12
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140047 ⟸ XM_063283977
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140055 ⟸ XM_063283985
- Peptide Label:	isoform X13
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140056 ⟸ XM_063283986
- Peptide Label:	isoform X15
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140050 ⟸ XM_063283980
- Peptide Label:	isoform X6
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140057 ⟸ XM_063283987
- Peptide Label:	isoform X16
- UniProtKB:	A0A8I6GKQ9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140059 ⟸ XM_063283989
- Peptide Label:	isoform X18
- UniProtKB:	F1M241 (UniProtKB/TrEMBL), A0A8I6GKQ9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140060 ⟸ XM_063283990
- Peptide Label:	isoform X19
- UniProtKB:	A6JEU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140051 ⟸ XM_063283981
- Peptide Label:	isoform X7
- UniProtKB:	A0A8I5ZKB0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140048 ⟸ XM_063283978
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6GKQ9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140049 ⟸ XM_063283979
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6GKQ9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140052 ⟸ XM_063283982
- Peptide Label:	isoform X9
- UniProtKB:	A0A8I6GKQ9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140061 ⟸ XM_063283991
- Peptide Label:	isoform X19
- UniProtKB:	A6JEU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140062 ⟸ XM_063283992
- Peptide Label:	isoform X20
- UniProtKB:	A6JEU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140063 ⟸ XM_063283993
- Peptide Label:	isoform X21
- UniProtKB:	A6JEU1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063140065 ⟸ XM_063283995
- Peptide Label:	isoform X23

RefSeq Acc Id:	XP_063140068 ⟸ XM_063283998
- Peptide Label:	isoform X26

RefSeq Acc Id:	XP_063140064 ⟸ XM_063283994
- Peptide Label:	isoform X22

RefSeq Acc Id:	XP_063140066 ⟸ XM_063283996
- Peptide Label:	isoform X24

RefSeq Acc Id:	XP_063140067 ⟸ XM_063283997
- Peptide Label:	isoform X25

Protein Domains

uDENN

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K6J1-F1-model_v2	AlphaFold	A0A0G2K6J1	1-1093	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307927	AgrOrtholog
BioCyc Gene	G2FUF-49916	BioCyc
Ensembl Genes	ENSRNOG00000010526	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000025443	ENTREZGENE
	ENSRNOT00000025443.5	UniProtKB/TrEMBL
	ENSRNOT00000091747.2	UniProtKB/TrEMBL
	ENSRNOT00000096396	ENTREZGENE
	ENSRNOT00000096396.1	UniProtKB/TrEMBL
	ENSRNOT00000097346	ENTREZGENE
	ENSRNOT00000097346.1	UniProtKB/TrEMBL
	ENSRNOT00000108920	ENTREZGENE
	ENSRNOT00000108920.1	UniProtKB/TrEMBL
	ENSRNOT00000116730	ENTREZGENE
	ENSRNOT00000116730.1	UniProtKB/TrEMBL
	ENSRNOT00000145932	ENTREZGENE
	ENSRNOT00000169280	ENTREZGENE
Gene3D-CATH	3.30.450.200	UniProtKB/TrEMBL
	3.40.50.11500	UniProtKB/TrEMBL
	6.10.140.1000	UniProtKB/TrEMBL
InterPro	dDENN_dom	UniProtKB/TrEMBL
	DENN_C	UniProtKB/TrEMBL
	DENN_dom	UniProtKB/TrEMBL
	DENND1A/B/C	UniProtKB/TrEMBL
	Tripartite_DENN	UniProtKB/TrEMBL
	uDENN_dom	UniProtKB/TrEMBL
NCBI Gene	311913	ENTREZGENE
PANTHER	DENN DOMAIN-CONTAINING PROTEIN 1A	UniProtKB/TrEMBL
	PTHR13196	UniProtKB/TrEMBL
Pfam	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
PhenoGen	Dennd1a	PhenoGen
PROSITE	DENN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000010526	RatGTEx
SMART	dDENN	UniProtKB/TrEMBL
	DENN	UniProtKB/TrEMBL
	uDENN	UniProtKB/TrEMBL
UniProt	A0A0G2K6J1_RAT	UniProtKB/TrEMBL
	A0A8I5ZKB0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZLU1_RAT	UniProtKB/TrEMBL
	A0A8I6A7I2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GKQ9	ENTREZGENE, UniProtKB/TrEMBL
	A6JEU1	ENTREZGENE, UniProtKB/TrEMBL
	B2GV78_RAT	UniProtKB/TrEMBL
	F1M241	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Dennd1a	DENN domain containing 1A	Dennd1a	DENN/MADD domain containing 1A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Dennd1a	DENN/MADD domain containing 1A	RGD1307927_predicted	similar to RIKEN cDNA 6030446I19 gene (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1307927_predicted	similar to RIKEN cDNA 6030446I19 gene (predicted)	LOC311913_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC311913_predicted	similar to RIKEN cDNA 6030446I19 gene (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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