![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tmem161a | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM161A mRNA | CTD | PMID:36331819 | Tmem161a | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TMEM161A mRNA | CTD | PMID:22206623 | Tmem161a | Rat | 17beta-estradiol | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | [Polyphenols co-treated with Estradiol] results in decreased expression of TMEM161A mRNA | CTD | PMID:30077407 | Tmem161a | Rat | 17beta-estradiol | decreases expression | ISO | Tmem161a (Mus musculus) | 6480464 | Estradiol results in decreased expression of TMEM161A mRNA | CTD | PMID:30077407 | Tmem161a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in increased expression of TMEM161A mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to TMEM161A promoter] | CTD | PMID:19465110 and PMID:19654925 | Tmem161a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM161A mRNA | CTD | PMID:33387578 | Tmem161a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | TMEM161A (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM161A mRNA | CTD | PMID:22574217 | Tmem161a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmem161a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM161A mRNA | CTD | PMID:21570461 | Tmem161a | Rat | 2-palmitoylglycerol | increases expression | ISO | TMEM161A (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of TMEM161A mRNA | CTD | PMID:37199045 | Tmem161a | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Tmem161a (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of TMEM161A mRNA | CTD | PMID:20188158 | Tmem161a | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Tmem161a (Mus musculus) | 6480464 | bisphenol S affects the methylation of TMEM161A gene | CTD | PMID:31683443 | Tmem161a | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TMEM161A mRNA | CTD | PMID:30047161 | Tmem161a | Rat | acrolein | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TMEM161A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TMEM161A mRNA | CTD | PMID:32699268 | Tmem161a | Rat | aflatoxin B1 | increases expression | ISO | Tmem161a (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of TMEM161A mRNA | CTD | PMID:19770486 | Tmem161a | Rat | aflatoxin B1 | increases methylation | ISO | TMEM161A (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of TMEM161A intron | CTD | PMID:30157460 | Tmem161a | Rat | alpha-pinene | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TMEM161A mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of TMEM161A mRNA | CTD | PMID:32699268 | Tmem161a | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of TMEM161A mRNA | CTD | PMID:30047161 | Tmem161a | Rat | arsane | affects methylation | ISO | TMEM161A (Homo sapiens) | 6480464 | Arsenic affects the methylation of TMEM161A gene | CTD | PMID:25304211 | Tmem161a | Rat | arsane | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TMEM161A mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TMEM161A mRNA | CTD | PMID:39836092 | Tmem161a | Rat | arsenic atom | affects methylation | ISO | TMEM161A (Homo sapiens) | 6480464 | Arsenic affects the methylation of TMEM161A gene | CTD | PMID:25304211 | Tmem161a | Rat | arsenic atom | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TMEM161A mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TMEM161A mRNA | CTD | PMID:39836092 | Tmem161a | Rat | arsenite(3-) | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to TMEM161A mRNA] | CTD | PMID:32406909 | Tmem161a | Rat | benzo[a]pyrene | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to TMEM161A promoter] | CTD | PMID:19654925 | Tmem161a | Rat | benzo[a]pyrene | affects methylation | ISO | TMEM161A (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TMEM161A intron | CTD | PMID:30157460 | Tmem161a | Rat | benzo[e]pyrene | increases methylation | ISO | TMEM161A (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of TMEM161A intron | CTD | PMID:30157460 | Tmem161a | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TMEM161A mRNA | CTD | PMID:25181051 | Tmem161a | Rat | chlorpyrifos | increases expression | ISO | Tmem161a (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TMEM161A mRNA | CTD | PMID:37019170 | Tmem161a | Rat | choline | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of TMEM161A mRNA | CTD | PMID:20938992 | Tmem161a | Rat | cisplatin | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TMEM161A mRNA | CTD | PMID:27392435 | Tmem161a | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of TMEM161A mRNA | CTD | PMID:23640034 | Tmem161a | Rat | Dibutyl phosphate | affects expression | ISO | TMEM161A (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TMEM161A mRNA | CTD | PMID:37042841 | Tmem161a | Rat | folic acid | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 | Tmem161a | Rat | folic acid | decreases expression | ISO | Tmem161a (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TMEM161A mRNA | CTD | PMID:25629700 | Tmem161a | Rat | L-methionine | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of TMEM161A mRNA | CTD | PMID:20938992 | Tmem161a | Rat | manganese atom | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TMEM161A mRNA | CTD | PMID:39836092 | Tmem161a | Rat | manganese(0) | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TMEM161A mRNA | CTD | PMID:39836092 | Tmem161a | Rat | manganese(II) chloride | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TMEM161A mRNA | CTD | PMID:39836092 | Tmem161a | Rat | methapyrilene | increases methylation | ISO | TMEM161A (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of TMEM161A intron | CTD | PMID:30157460 | Tmem161a | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of TMEM161A mRNA | CTD | PMID:30047161 | Tmem161a | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | TMEM161A (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of TMEM161A mRNA | CTD | PMID:24810058 | Tmem161a | Rat | ozone | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of TMEM161A mRNA more ... | CTD | PMID:32699268 | Tmem161a | Rat | paracetamol | affects expression | ISO | Tmem161a (Mus musculus) | 6480464 | Acetaminophen affects the expression of TMEM161A mRNA | CTD | PMID:17562736 | Tmem161a | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TMEM161A mRNA | CTD | PMID:33387578 | Tmem161a | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tmem161a (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM161A mRNA | CTD | PMID:36331819 | Tmem161a | Rat | pirinixic acid | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TMEM161A mRNA | CTD | PMID:19710929 | Tmem161a | Rat | pirinixic acid | decreases expression | ISO | Tmem161a (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TMEM161A mRNA | CTD | PMID:23811191 | Tmem161a | Rat | sodium arsenite | multiple interactions | ISO | TMEM161A (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in increased expression of TMEM161A mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TMEM161A mRNA | CTD | PMID:39836092 | Tmem161a | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of TMEM161A mRNA | CTD | PMID:19281266 | Tmem161a | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of TMEM161A mRNA | CTD | PMID:30047161 | Tmem161a | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TMEM161A mRNA | CTD | PMID:34492290 | Tmem161a | Rat | thiram | decreases expression | ISO | TMEM161A (Homo sapiens) | 6480464 | Thiram results in decreased expression of TMEM161A mRNA | CTD | PMID:38568856 | Tmem161a | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of TMEM161A mRNA | CTD | PMID:33387578 | Tmem161a | Rat | triptonide | increases expression | ISO | Tmem161a (Mus musculus) | 6480464 | triptonide results in increased expression of TMEM161A mRNA | CTD | PMID:33045310 | Tmem161a | Rat | valproic acid | affects expression | ISO | TMEM161A (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TMEM161A mRNA | CTD | PMID:25979313 | Tmem161a | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of TMEM161A mRNA | CTD | PMID:23869203 | |