Rbm20 (RNA binding motif protein 20) - Rat Genome Database

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Gene: Rbm20 (RNA binding motif protein 20) Rattus norvegicus
Analyze
Symbol: Rbm20
Name: RNA binding motif protein 20
RGD ID: 1307427
Description: Enables pre-mRNA intronic binding activity. Involved in heart formation; negative regulation of mRNA splicing, via spliceosome; and regulation of alternative mRNA splicing, via spliceosome. Located in cytoplasmic ribonucleoprotein granule. Is active in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy and dilated cardiomyopathy 1DD. Orthologous to human RBM20 (RNA binding motif protein 20); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC309544; probable RNA-binding protein 20; RNA-binding motif protein 20; RNA-binding protein 20
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Rbm20m1Mlgw   Rbm20em5Mcwi   Rbm20em10Mcwi   Rbm20em8Mcwi  
Genetic Models: (SDxF344)F1-Rbm20m1Mlgw (SDxF344)F1xBN-Rbm20m1Mlgw+/+ (SDxF344)F1-Rbm20m1Mlgw+/+ (SDxF344)F1xBN-Rbm20m1Mlgw SS-Rbm20em5Mcwi SS-Rbm20em10Mcwi SS-Rbm20em8Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81262,671,311 - 262,912,551 (+)NCBIGRCr8
mRatBN7.21252,683,760 - 252,907,465 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1252,683,771 - 252,886,060 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1260,872,977 - 261,075,647 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01267,579,046 - 267,781,723 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01260,234,755 - 260,437,091 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01274,391,932 - 274,589,816 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1274,391,932 - 274,589,816 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01281,783,646 - 282,003,053 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41259,905,545 - 260,144,190 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11260,300,378 - 260,352,579 (+)NCBI
Celera1248,402,941 - 248,600,603 (+)NCBICelera
Cytogenetic Map1q55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasmic ribonucleoprotein granule  (IDA,ISO)
nucleus  (IBA,IDA,IEA,ISO,ISS)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Mutations in ribonucleic acid binding protein gene cause familial dilated cardiomyopathy. Brauch KM, etal., J Am Coll Cardiol. 2009 Sep 1;54(10):930-41. doi: 10.1016/j.jacc.2009.05.038.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing. Guo W, etal., Nat Med. 2012 May;18(5):766-73. doi: 10.1038/nm.2693.
4. Pathophysiological defects and transcriptional profiling in the RBM20-/- rat model. Guo W, etal., PLoS One. 2013 Dec 19;8(12):e84281. doi: 10.1371/journal.pone.0084281. eCollection 2013.
5. RBM20 and RBM24 cooperatively promote the expression of short enh splice variants. Ito J, etal., FEBS Lett. 2016 Jul;590(14):2262-74. doi: 10.1002/1873-3468.12251. Epub 2016 Jul 4.
6. Rbm20 regulates titin alternative splicing as a splicing repressor. Li S, etal., Nucleic Acids Res. 2013 Feb 1;41(4):2659-72. doi: 10.1093/nar/gks1362. Epub 2013 Jan 9.
7. RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing. Maatz H, etal., J Clin Invest. 2014 Aug;124(8):3419-30. doi: 10.1172/JCI74523. Epub 2014 Jun 24.
8. RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and Differential Hormonal Responses between Muscles and in Muscle Cell Cultures. Maimaiti R, etal., Int J Mol Sci. 2021 Mar 13;22(6). pii: ijms22062928. doi: 10.3390/ijms22062928.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis. Zhang Y, etal., FASEB J. 2022 May;36(5):e22302. doi: 10.1096/fj.202101811RR.
14. RBM20 is an essential factor for thyroid hormone-regulated titin isoform transition. Zhu C, etal., J Mol Cell Biol. 2015 Feb;7(1):88-90. doi: 10.1093/jmcb/mjv002. Epub 2015 Jan 8.
Additional References at PubMed
PMID:28676430   PMID:29725258   PMID:30133019   PMID:31221019   PMID:31717392   PMID:35762193  


Genomics

Comparative Map Data
Rbm20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81262,671,311 - 262,912,551 (+)NCBIGRCr8
mRatBN7.21252,683,760 - 252,907,465 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1252,683,771 - 252,886,060 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1260,872,977 - 261,075,647 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01267,579,046 - 267,781,723 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01260,234,755 - 260,437,091 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01274,391,932 - 274,589,816 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1274,391,932 - 274,589,816 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01281,783,646 - 282,003,053 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41259,905,545 - 260,144,190 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11260,300,378 - 260,352,579 (+)NCBI
Celera1248,402,941 - 248,600,603 (+)NCBICelera
Cytogenetic Map1q55NCBI
RBM20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810110,643,245 - 110,839,468 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10110,644,336 - 110,839,468 (+)EnsemblGRCh38hg38GRCh38
GRCh3710112,404,094 - 112,599,226 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610112,394,203 - 112,589,217 (+)NCBINCBI36Build 36hg18NCBI36
Celera10106,135,726 - 106,330,820 (+)NCBICelera
Cytogenetic Map10q25.2NCBI
HuRef10106,033,283 - 106,228,064 (+)NCBIHuRef
CHM1_110112,685,947 - 112,881,061 (+)NCBICHM1_1
T2T-CHM13v2.010111,526,746 - 111,723,237 (+)NCBIT2T-CHM13v2.0
Rbm20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391953,649,422 - 53,855,514 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1953,665,737 - 53,855,511 (+)EnsemblGRCm39 Ensembl
GRCm381953,660,989 - 53,867,083 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1953,677,306 - 53,867,080 (+)EnsemblGRCm38mm10GRCm38
MGSCv371953,751,796 - 53,941,570 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361953,730,363 - 53,919,025 (+)NCBIMGSCv36mm8
MGSCv361953,676,844 - 53,880,034 (+)NCBIMGSCv36mm8
Celera1955,870,376 - 56,061,918 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1948.28NCBI
Rbm20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955485586,373 - 769,635 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955485590,094 - 769,604 (-)NCBIChiLan1.0ChiLan1.0
RBM20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28122,528,458 - 122,721,290 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110122,533,794 - 122,726,626 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010107,240,854 - 107,433,749 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110110,767,653 - 110,882,909 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10110,822,255 - 110,882,909 (+)Ensemblpanpan1.1panPan2
RBM20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12821,971,424 - 22,162,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2821,971,504 - 22,161,476 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2822,243,625 - 22,314,911 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02822,616,330 - 22,687,337 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2822,496,586 - 22,687,315 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12822,175,756 - 22,246,804 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02822,182,299 - 22,253,611 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02822,316,433 - 22,387,379 (+)NCBIUU_Cfam_GSD_1.0
Rbm20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721323,908,959 - 24,089,243 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364861,472,227 - 1,653,209 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364861,472,170 - 1,652,314 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBM20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14121,210,666 - 121,269,823 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114121,058,896 - 121,269,824 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214131,944,861 - 132,146,766 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RBM20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19103,583,722 - 103,775,391 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9103,703,569 - 103,777,934 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604864,923,022 - 64,982,689 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbm20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473735,477,521 - 35,545,242 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473735,479,621 - 35,660,357 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbm20
1388 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:801
Count of miRNA genes:329
Interacting mature miRNAs:439
Transcripts:ENSRNOT00000054685
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1238699859259647894Rat
631836Stl31Serum triglyceride level QTL 314.645e-06blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat
1600384Niddm66Non-insulin dependent diabetes mellitus QTL 660.000005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1252645447253439819Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
1598839Rf56Renal function QTL 56renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1245907761257976495Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233190394258625266Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat

Markers in Region
RH143918  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21252,683,081 - 252,683,263 (+)MAPPERmRatBN7.2
Rnor_6.01274,391,254 - 274,391,435NCBIRnor6.0
Rnor_5.01281,800,803 - 281,800,984UniSTSRnor5.0
RGSC_v3.41259,904,867 - 259,905,048UniSTSRGSC3.4
Celera1248,402,213 - 248,402,394UniSTS
RH 3.4 Map11673.1UniSTS
Cytogenetic Map1q55UniSTS
RH141597  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21252,883,185 - 252,883,366 (+)MAPPERmRatBN7.2
Rnor_6.01274,586,942 - 274,587,122NCBIRnor6.0
Rnor_5.01282,000,179 - 282,000,359UniSTSRnor5.0
RGSC_v3.41260,141,316 - 260,141,496UniSTSRGSC3.4
Celera1248,597,729 - 248,597,909UniSTS
RH 3.4 Map11665.2UniSTS
Cytogenetic Map1q55UniSTS


Genetic Models
This gene Rbm20 is modified in the following models/strains:
(SDxF344)F1-Rbm20m1Mlgw     (SDxF344)F1xBN-Rbm20m1Mlgw+/+     (SDxF344)F1-Rbm20m1Mlgw+/+     (SDxF344)F1xBN-Rbm20m1Mlgw     SS-Rbm20em5Mcwi     SS-Rbm20em10Mcwi     SS-Rbm20em8Mcwi    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 89 88 57 25 57 6 216 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000054685   ⟹   ENSRNOP00000051570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1252,683,771 - 252,886,060 (+)Ensembl
Rnor_6.0 Ensembl1274,391,932 - 274,589,816 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110758   ⟹   ENSRNOP00000096791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1252,834,919 - 252,886,060 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113904   ⟹   ENSRNOP00000091922
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1252,814,422 - 252,886,060 (+)Ensembl
RefSeq Acc Id: NM_001107611   ⟹   NP_001101081
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,689,075 - 262,891,364 (+)NCBI
mRatBN7.21252,683,760 - 252,886,060 (+)NCBI
Rnor_6.01274,391,932 - 274,589,816 (+)NCBI
Rnor_5.01281,783,646 - 282,003,053 (+)NCBI
RGSC_v3.41259,905,545 - 260,144,190 (+)RGD
Celera1248,402,941 - 248,600,603 (+)RGD
Sequence:
RefSeq Acc Id: XM_017589306   ⟹   XP_017444795
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,818,559 - 262,882,894 (+)NCBI
mRatBN7.21252,813,348 - 252,886,059 (+)NCBI
Rnor_6.01274,515,780 - 274,587,161 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039080732   ⟹   XP_038936660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,686,539 - 262,912,551 (+)NCBI
mRatBN7.21252,683,862 - 252,907,465 (+)NCBI
RefSeq Acc Id: XM_039080742   ⟹   XP_038936670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,818,559 - 262,882,894 (+)NCBI
mRatBN7.21252,813,347 - 252,886,059 (+)NCBI
RefSeq Acc Id: XM_039080744   ⟹   XP_038936672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,853,115 - 262,882,894 (+)NCBI
mRatBN7.21252,845,164 - 252,886,059 (+)NCBI
RefSeq Acc Id: XM_063265322   ⟹   XP_063121392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,686,534 - 262,882,894 (+)NCBI
RefSeq Acc Id: XM_063265325   ⟹   XP_063121395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,769,766 - 262,882,894 (+)NCBI
RefSeq Acc Id: XM_063265327   ⟹   XP_063121397
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,671,311 - 262,882,894 (+)NCBI
RefSeq Acc Id: XM_063265334   ⟹   XP_063121404
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81262,848,503 - 262,882,894 (+)NCBI
RefSeq Acc Id: NP_001101081   ⟸   NM_001107611
- UniProtKB: C1IEE3 (UniProtKB/Swiss-Prot),   E9PT37 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017444795   ⟸   XM_017589306
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AGI3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000051570   ⟸   ENSRNOT00000054685
RefSeq Acc Id: XP_038936660   ⟸   XM_039080732
- Peptide Label: isoform X3
- UniProtKB: E9PT37 (UniProtKB/Swiss-Prot),   C1IEE3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038936670   ⟸   XM_039080742
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AGI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936672   ⟸   XM_039080744
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000096791   ⟸   ENSRNOT00000110758
Ensembl Acc Id: ENSRNOP00000091922   ⟸   ENSRNOT00000113904
RefSeq Acc Id: XP_063121397   ⟸   XM_063265327
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AGI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121392   ⟸   XM_063265322
- Peptide Label: isoform X1
- UniProtKB: E9PT37 (UniProtKB/Swiss-Prot),   C1IEE3 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063121395   ⟸   XM_063265325
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AGI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063121404   ⟸   XM_063265334
- Peptide Label: isoform X4
Protein Domains
Matrin-type   RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PT37-F1-model_v2 AlphaFold E9PT37 1-1207 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307427 AgrOrtholog
BioCyc Gene G2FUF-55380 BioCyc
Ensembl Genes ENSRNOG00000014705 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000054685.3 UniProtKB/Swiss-Prot
  ENSRNOT00000110758.1 UniProtKB/TrEMBL
  ENSRNOT00000113904.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Matrin/U1-C_Znf_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Matrin/U1-like-C_Znf_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBM20_RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:309544 UniProtKB/Swiss-Prot
NCBI Gene 309544 ENTREZGENE
PANTHER MATRIN 3/NUCLEAR PROTEIN 220-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15592:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rbm20 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZF_MATRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014705 RatGTEx
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnF_U1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AGI3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AR99_RAT UniProtKB/TrEMBL
  C1IEE3 ENTREZGENE
  E9PT37 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary C1IEE3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Rbm20  RNA binding motif protein 20   Rbm20_predicted  RNA binding motif protein 20 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rbm20_predicted  RNA binding motif protein 20 (predicted)      Symbol and Name status set to approved 70820 APPROVED