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Gene: Surf6 (surfeit 6) Rattus norvegicus

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Symbol:

Surf6

Name:

surfeit 6

RGD ID:

1307382

Description:

Predicted to enable DNA binding activity; RNA binding activity; and molecular condensate scaffold activity. Predicted to be involved in ribosomal large subunit biogenesis and ribosomal small subunit biogenesis. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in chromosome; granular component; and nucleoplasm. Predicted to be active in nucleolus. Orthologous to human SURF6 (surfeit 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC108352178; LOC311823; MGC109125; Surf6_predicted; surfeit gene 6; surfeit gene 6 (predicted); surfeit locus protein 6; surfeit locus protein 6-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SURF6 (surfeit 6)	HGNC	Ensembl, HomoloGene, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Surf6 (surfeit gene 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Surf6 (surfeit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SURF6 (surfeit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SURF6 (surfeit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Surf6 (surfeit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SURF6 (surfeit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SURF6 (surfeit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Surf6 (surfeit 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NSUN6 (NOP2/Sun RNA methyltransferase 6)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SURF6 (surfeit 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Surf6 (surfeit gene 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ZK546.14	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	RRP14	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Surf6	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	surf6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	30,619,525 - 30,630,388 (-)	NCBI		GRCr8
mRatBN7.2	3	10,221,450 - 10,232,306 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	10,221,452 - 10,232,251 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	13,281,440 - 13,292,254 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	21,866,841 - 21,877,655 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	20,122,142 - 20,132,956 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	5,441,404 - 5,452,156 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	5,441,409 - 5,452,156 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	10,803,314 - 10,814,066 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	5,790,323 - 5,801,072 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	5,790,623 - 5,801,372 (-)	NCBI
Celera	3	5,019,513 - 5,030,262 (-)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 14 (ISO)

Ehlers-Danlos syndrome classic type 1 (ISO)

Leigh disease (ISO)

primary coenzyme Q10 deficiency 7 (ISO)

Rafiq syndrome (ISO)

tuberous sclerosis 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

4,4'-diaminodiphenylmethane (ISO)

aflatoxin B1 (EXP,ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

carbon nanotube (ISO)

cefaloridine (EXP)

chlordecone (ISO)

cisplatin (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

decabromodiphenyl ether (EXP)

Dibutyl phosphate (ISO)

dioxygen (ISO)

enzyme inhibitor (ISO)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

lead(0) (ISO)

N-nitrosodiethylamine (EXP)

ozone (ISO)

paracetamol (ISO)

PCB138 (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ribosomal large subunit biogenesis (IBA)

ribosomal small subunit biogenesis (IBA)

ribosome biogenesis (ISO)

Cellular Component

chromosome (ISO)

granular component (ISO)

nucleolus (IBA,ISO)

nucleoplasm (ISO)

Molecular Function

DNA binding (IBA,ISO)

molecular condensate scaffold activity (ISO)

protein binding (ISO)

RNA binding (IBA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8639267	PMID:9548374	PMID:12477932	PMID:16855206	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Surf6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	30,619,525 - 30,630,388 (-)	NCBI		GRCr8
mRatBN7.2	3	10,221,450 - 10,232,306 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	10,221,452 - 10,232,251 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	13,281,440 - 13,292,254 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	21,866,841 - 21,877,655 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	20,122,142 - 20,132,956 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	5,441,404 - 5,452,156 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	5,441,409 - 5,452,156 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	10,803,314 - 10,814,066 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	5,790,323 - 5,801,072 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	5,790,623 - 5,801,372 (-)	NCBI
Celera	3	5,019,513 - 5,030,262 (-)	NCBI		Celera
Cytogenetic Map	3	p13	NCBI

SURF6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	133,328,776 - 133,336,188 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	133,328,776 - 133,336,188 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	136,195,612 - 136,203,025 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	135,187,373 - 135,192,868 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	9	133,227,106 - 133,232,598	NCBI
Celera	9	106,748,057 - 106,753,551 (-)	NCBI		Celera
Cytogenetic Map	9	q34.2	NCBI
HuRef	9	105,697,497 - 105,702,999 (-)	NCBI		HuRef
CHM1_1	9	136,347,741 - 136,353,244 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	145,542,703 - 145,550,115 (-)	NCBI		T2T-CHM13v2.0

Surf6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	26,780,430 - 26,792,899 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	26,778,640 - 26,792,891 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	26,890,418 - 26,902,887 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	26,888,628 - 26,902,879 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	26,746,292 - 26,758,333 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	26,712,781 - 26,724,829 (-)	NCBI		MGSCv36	mm8
Celera	2	26,600,515 - 26,612,557 (-)	NCBI		Celera
Cytogenetic Map	2	A3	NCBI
cM Map	2	19.08	NCBI

Surf6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955513	2,692,806 - 2,696,481 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955513	2,691,648 - 2,696,018 (-)	NCBI	ChiLan1.0	ChiLan1.0

SURF6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	6,016,970 - 6,024,335 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	6,019,310 - 6,026,671 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	104,453,832 - 104,459,589 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	133,064,755 - 133,070,302 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	133,064,755 - 133,070,302 (-)	Ensembl	panpan1.1		panPan2

SURF6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	49,769,338 - 49,774,136 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	49,050,875 - 49,055,669 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	50,643,360 - 50,648,222 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	50,642,893 - 50,648,773 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	49,405,912 - 49,410,703 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	49,747,372 - 49,752,154 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	49,825,278 - 49,830,139 (-)	NCBI		UU_Cfam_GSD_1.0

Surf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	199,827,029 - 199,831,820 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936669	3,542,644 - 3,548,762 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936669	3,543,250 - 3,548,756 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SURF6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	272,949,247 - 272,955,197 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	272,949,236 - 272,955,674 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SURF6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	4,803,231 - 4,804,973 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666058	181,666 - 187,771 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Surf6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	1,797,740 - 1,804,231 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	1,799,764 - 1,804,194 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Surf6
41 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	769
Count of miRNA genes:	300
Interacting mature miRNAs:	400
Transcripts:	ENSRNOT00000006699
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	8658162	27494778	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
2292615	Ept17	Estrogen-induced pituitary tumorigenesis QTL 17	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6537645	10778823	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	8227194	33703538	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	31158234	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	8658162	27494778	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	27494778	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	33278763	Rat
1358185	Ept6	Estrogen-induced pituitary tumorigenesis QTL 6	6.7		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	6537645	10778823	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	33230976	Rat

Markers in Region

AW212655

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	10,234,035 - 10,234,169 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	4,862,035 - 4,862,168	NCBI	Rnor6.0
Rnor_6.0	3	5,453,960 - 5,454,093	NCBI	Rnor6.0
Rnor_5.0	3	10,217,232 - 10,217,365	UniSTS	Rnor5.0
Rnor_5.0	3	10,815,870 - 10,816,003	UniSTS	Rnor5.0
RGSC_v3.4	3	5,802,876 - 5,803,009	UniSTS	RGSC3.4
Celera	3	5,032,066 - 5,032,199	UniSTS
Cytogenetic Map	3	p12	UniSTS

RH133460

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	10,232,601 - 10,232,800 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	5,452,526 - 5,452,724	NCBI	Rnor6.0
Rnor_6.0	3	4,860,602 - 4,860,800	NCBI	Rnor6.0
Rnor_5.0	3	10,215,799 - 10,215,997	UniSTS	Rnor5.0
Rnor_5.0	3	10,814,436 - 10,814,634	UniSTS	Rnor5.0
RGSC_v3.4	3	5,801,442 - 5,801,640	UniSTS	RGSC3.4
Celera	3	5,030,632 - 5,030,830	UniSTS
Cytogenetic Map	3	p12	UniSTS

BF396659

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	31,174,589 - 31,174,867 (+)	MAPPER	mRatBN7.2
mRatBN7.2	3	10,221,573 - 10,221,794 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	5,441,528 - 5,441,748	NCBI	Rnor6.0
Rnor_6.0	10	31,869,745 - 31,870,022	NCBI	Rnor6.0
Rnor_5.0	10	31,691,075 - 31,691,352	UniSTS	Rnor5.0
Rnor_5.0	3	10,803,438 - 10,803,658	UniSTS	Rnor5.0
RGSC_v3.4	3	5,790,444 - 5,790,664	UniSTS	RGSC3.4
RGSC_v3.4	10	31,880,905 - 31,881,182	UniSTS	RGSC3.4
Celera	10	30,619,422 - 30,619,699	UniSTS
Celera	3	5,019,634 - 5,019,854	UniSTS
RH 3.4 Map	3	21.9	UniSTS
Cytogenetic Map	3	p12	UniSTS

RH141946

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	10,221,589 - 10,221,794 (+)	MAPPER	mRatBN7.2
mRatBN7.2	10	31,174,657 - 31,174,867 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	31,869,813 - 31,870,022	NCBI	Rnor6.0
Rnor_6.0	3	5,441,544 - 5,441,748	NCBI	Rnor6.0
Rnor_5.0	10	31,691,143 - 31,691,352	UniSTS	Rnor5.0
Rnor_5.0	3	10,803,454 - 10,803,658	UniSTS	Rnor5.0
RGSC_v3.4	3	5,790,460 - 5,790,664	UniSTS	RGSC3.4
RGSC_v3.4	10	31,880,973 - 31,881,182	UniSTS	RGSC3.4
Celera	10	30,619,490 - 30,619,699	UniSTS
Celera	3	5,019,650 - 5,019,854	UniSTS
RH 3.4 Map	3	21.9	UniSTS
Cytogenetic Map	3	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001015014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233784	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC126134	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC091270	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006699 ⟹ ENSRNOP00000006699

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	10,221,452 - 10,232,251 (-)	Ensembl
Rnor_6.0 Ensembl	3	5,441,409 - 5,452,156 (-)	Ensembl

RefSeq Acc Id:

NM_001015014 ⟹ NP_001015014

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	30,619,528 - 30,630,307 (-)	NCBI
mRatBN7.2	3	10,221,453 - 10,232,232 (-)	NCBI
Rnor_6.0	3	5,441,407 - 5,452,156 (-)	NCBI
Rnor_5.0	3	10,803,314 - 10,814,066 (-)	NCBI
RGSC_v3.4	3	5,790,323 - 5,801,072 (-)	RGD
Celera	3	5,019,513 - 5,030,262 (-)	RGD

Sequence:

show sequence

CGGGACCCTCTGATTGTAGCTCCAGCCCTGGTTGCTAACATGGCTTCTCTCCTGGCTAAGGATG
CCTATCTGCAGGACTTGGCCAAGAAAATCTGCGCGCAGCCTGGCCCTGAGCGGCAGAGGAGCCA
GTGGGCTGTCAGAACAAAAGGCTCAGAAGCTGCTGGACCCCCAAAAAAGAAAAGGAAGAAAACA
CAAAATAAGTCTCGGAAGCAGGAGGAGAAAACTATGGAGCACAAGACTAAACCCCTGGGCAAGA
AGTCTCCCACCTCTTCTAGTGCCAAGAAACCAGGGCTATCCAAACAAGGGAGCTCCGGCTCCCT
GGGGTCCCCTGAAGATAGCCGAGGCACAGCGCCCGATTCTGTCTTTGCACTGGATTTCCTGAGA
CAGCGGCTGCATGAGAAGATCCAGATGGCCCGGGGCCAGGGTGGCACCAAGGAGCTGTCTGCTG
CCACTCTAGAAAAAAGACAGCGGAGAAAGCAGGAGAGGGAACGGAAGAAAAGGAAGCGGAGGGA
GCTCCGAGCAAAGCAGCAGGTTGCAGAGGCTGAGAAAAAGGAGGAACCAGTCAAGGCGCCCCCC
AAAATGGCCTGCAAGGATCTGCAGGAATCAGGGCTGATCTTTAATAAGGTGGAGGTAGCTGGAG
AGGAGCCAGCCAGCAAGGCCCAGCGCAAGAAGGAGAAGCGGCAGCAGGTGAAGGGGAACTTGAC
CCCTCTGACAGGCAGGAACTATAGGCAGCTGCTGGACCGTCTGCATGCCCGGCAGGGCCGGGTG
GAGGAGCTTCGCGATCAGGATGCAGGCAAGGCCCAGGAGCTGGAGGCCAAGATGAAGTGGACCA
ACTTGCTGTACAAGGCAGAGGGTGTGAAGATCAGGGACGATGAGCGCCTGCTGCAGGAGGCCCT
GAAGCGCAAAGAGAAGCGCCGGGCACAGCGGCAGCGCAAGTGGGAGAAGCGTTCGGAGCATGTG
GTGGAGAAGATGCAGCAGCGACAGGACAAGCGACGCCAGAACCTGCGCAAGAAGAAGGCAGCTC
GGGCCGAGCGACGGCTACAGAAGGCCCGCAAGAAGGGCCGGGTGCTGCCCCAGGACCTGGAGCG
TGCAGGCCTCTCCTGAGAGCTTGCACCTGCCAGGTTCCTGGCTGGGCACCTTCCTACCTGGCTT
CCATCCATCTCCATCCTTGAGGGTTGAGGTGGTATGTGGTGACAGACTGGGTCTCCTGTGAGGT
TGACAGTTCTTGCACCCCACAACCAAAGTGAGATCTGACTGCGTGCCAGGACGTTTCAGCAGCA
TCCTTAAGGAAGACCGTGTTTCCCGTTCCTGAGAGGGATGAAGGGGATCTGTGCCCGTGTCTTG
TGAGGGGTGTGTCACTGTGTCTGTATGTCTGTGTATGTCTGTGTTCTGAATGCTCCAGAGTTGG
GATAGAGGTTGGGGTGAGGTACCCCACTCACTCCTTCCTGCCCACCTGGTATATCCAGGGGCCA
TGAGAACAAAAGGTTTTGACTACTTGTTCTGTATCCACTAGTCTTGGGAACAGAGAAGAGGGCC
CAAGAGTTTTGGGAGAATCTGATCCAGTCAGATATGTCTCTGGGCCAGAGCTTGAGAGCTGTGT
TGAAGGCCAGCATCCAGCTCAAAAATCTAGAGTCCTTCCTGAGTCCCAGGATGTGCTTGCTCAC
CTGTGAGCCAGTCAATGGCTGCGACTTACATGTCGCCTAGTTTTATGTCAGTTTAATACAAACT
GGAGTTGTCTGAGAAGAGAGTGCCTCAACTGAGAACCCCGCTAGATTGGCCTGTGGTGCTTTTT
TTTAAAAAACAAAAAAACCTGGTGAATGATATGGTAGGGCCTGGTTCATTGTGGCTAGTGCCAC
CCCCGGACTGACGGTCCTGGGTTGTTTAAGAAAGTAGGCCAAGCCAGCTGTCGGGGACAAGCCA
TTAAGTAGCTTTTGCTTCAGTTCCTGCGTCTAGGTTCCTGCCCTGGCTTCCCTTGGTGATGTAC
TGTTACCTGGAAATGTAACATGAAGTAAACCCTTTCCTCAAAAAAAAAAAAAAAAAAAAAAAAA
A

hide sequence

RefSeq Acc Id:

XM_006233784 ⟹ XP_006233846

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	30,619,525 - 30,630,388 (-)	NCBI
mRatBN7.2	3	10,221,450 - 10,232,306 (-)	NCBI
Rnor_6.0	3	5,441,404 - 5,452,017 (-)	NCBI
Rnor_5.0	3	10,803,314 - 10,814,066 (-)	NCBI

Sequence:

show sequence

CATCCGGCCCGAGCAGCCTTTGGGAATGGACGCCGTCGTCTGGGGCCCGCTGTCCTAGGTCGGG
GCCGGACCCTCCACAAGGGATATGAGTTCGACTGTCAGAACAAAAGGCTCAGAAGCTGCTGGAC
CCCCAAAAAAGAAAAGGAAGAAAACACAAAATAAGTCTCGGAAGCAGGAGGAGAAAACTATGGA
GCACAAGACTAAACCCCTGGGCAAGAAGTCTCCCACCTCTTCTAGTGCCAAGAAACCAGGGCTA
TCCAAACAAGGGAGCTCCGGCTCCCTGGGGTCCCCTGAAGATAGCCGAGGCACAGCGCCCGATT
CTGTCTTTGCACTGGATTTCCTGAGACAGCGGCTGCATGAGAAGATCCAGATGGCCCGGGGCCA
GGGTGGCACCAAGGAGCTGTCTGCTGCCACTCTAGAAAAAAGACAGCGGAGAAAGCAGGAGAGG
GAACGGAAGAAAAGGAAGCGGAGGGAGCTCCGAGCAAAGCAGCAGGTTGCAGAGGCTGAGAAAA
AGGAGGAACCAGTCAAGGCGCCCCCCAAAATGGCCTGCAAGGATCTGCAGGAATCAGGGCTGAT
CTTTAATAAGGTGGAGGTAGCTGGAGAGGAGCCAGCCAGCAAGGCCCAGCGCAAGAAGGAGAAG
CGGCAGCAGGTGAAGGGGAACTTGACCCCTCTGACAGGCAGGAACTATAGGCAGCTGCTGGACC
GTCTGCATGCCCGGCAGGGCCGGGTGGAGGAGCTTCGCGATCAGGATGCAGGCAAGGCCCAGGA
GCTGGAGGCCAAGATGAAGTGGACCAACTTGCTGTACAAGGCAGAGGGTGTGAAGATCAGGGAC
GATGAGCGCCTGCTGCAGGAGGCCCTGAAGCGCAAAGAGAAGCGCCGGGCACAGCGGCAGCGCA
AGTGGGAGAAGCGTTCGGAGCATGTGGTGGAGAAGATGCAGCAGCGACAGGACAAGCGACGCCA
GAACCTGCGCAAGAAGAAGGCAGCTCGGGCCGAGCGACGGCTACAGAAGGCCCGCAAGAAGGGC
CGGGTGCTGCCCCAGGACCTGGAGCGTGCAGGCCTCTCCTGAGAGCTTGCACCTGCCAGGTTCC
TGGCTGGGCACCTTCCTACCTGGCTTCCATCCATCTCCATCCTTGAGGGTTGAGGTGGTATGTG
GTGACAGACTGGGTCTCCTGTGAGGTTGACAGTTCTTGCACCCCACAACCAAAGTGAGATCTGA
CTGCGTGCCAGGACGTTTCAGCAGCATCCTTAAGGAAGACCGTGTTTCCCGTTCCTGAGAGGGA
TGAAGGGGATCTGTGCCCGTGTCTTGTGAGGGGTGTGTCACTGTGTCTGTATGTCTGTGTATGT
CTGTGTTCTGAATGCTCCAGAGTTGGGATAGAGGTTGGGGTGAGGTACCCCACTCACTCCTTCC
TGCCCACCTGGTATATCCAGGGGCCATGAGAACAAAAGGTTTTGACTACTTGTTCTGTATCCAC
TAGTCTTGGGAACAGAGAAGAGGGCCCAAGAGTTTTGGGAGAATCTGATCCAGTCAGATATGTC
TCTGGGCCAGAGCTTGAGAGCTGTGTTGAAGGCCAGCATCCAGCTCAAAAATCTAGAGTCCTTC
CTGAGTCCCAGGATGTGCTTGCTCACCTGTGAGCCAGTCAATGGCTGCGACTTACATGTCGCCT
AGTTTTATGTCAGTTTAATACAAACTGGAGTTGTCTGAGAAGAGAGTGCCTCAACTGAGAACCC
CGCTAGATTGGCCTGTGGTGCTTTTTTTTAAAAAACAAAAAAACCTGGTGAATGATATGGTAGG
GCCTGGTTCATTGTGGCTAGTGCCACCCCCGGACTGACGGTCCTGGGTTGTTTAAGAAAGTAGG
CCAAGCCAGCTGTCGGGGACAAGCCATTAAGTAGCTTTTGCTTCAGTTCCTGCGTCTAGGTTCC
TGCCCTGGCTTCCCTTGGTGATGTACTGTTACCTGGAAATGTAACATGAAGTAAACCCTTTCCT
CAAGTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001015014	(Get FASTA)	NCBI Sequence Viewer
	XP_006233846	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91270	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006699.4

RefSeq Acc Id:

NP_001015014 ⟸ NM_001015014

- UniProtKB:

Q5BJZ4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MASLLAKDAYLQDLAKKICAQPGPERQRSQWAVRTKGSEAAGPPKKKRKKTQNKSRKQEEKTME
HKTKPLGKKSPTSSSAKKPGLSKQGSSGSLGSPEDSRGTAPDSVFALDFLRQRLHEKIQMARGQ
GGTKELSAATLEKRQRRKQERERKKRKRRELRAKQQVAEAEKKEEPVKAPPKMACKDLQESGLI
FNKVEVAGEEPASKAQRKKEKRQQVKGNLTPLTGRNYRQLLDRLHARQGRVEELRDQDAGKAQE
LEAKMKWTNLLYKAEGVKIRDDERLLQEALKRKEKRRAQRQRKWEKRSEHVVEKMQQRQDKRRQ
NLRKKKAARAERRLQKARKKGRVLPQDLERAGLS

hide sequence

RefSeq Acc Id:	XP_006233846 ⟸ XM_006233784
- Peptide Label:	isoform X1
- UniProtKB:	F7F149 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSTVRTKGSEAAGPPKKKRKKTQNKSRKQEEKTMEHKTKPLGKKSPTSSSAKKPGLSKQGSSG SLGSPEDSRGTAPDSVFALDFLRQRLHEKIQMARGQGGTKELSAATLEKRQRRKQERERKKRKR RELRAKQQVAEAEKKEEPVKAPPKMACKDLQESGLIFNKVEVAGEEPASKAQRKKEKRQQVKGN LTPLTGRNYRQLLDRLHARQGRVEELRDQDAGKAQELEAKMKWTNLLYKAEGVKIRDDERLLQE ALKRKEKRRAQRQRKWEKRSEHVVEKMQQRQDKRRQNLRKKKAARAERRLQKARKKGRVLPQDL ERAGLS hide sequence

Ensembl Acc Id:

ENSRNOP00000006699 ⟸ ENSRNOT00000006699

Protein Domains

Ribosomal RNA-processing protein 14/surfeit locus

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5BJZ4-F1-model_v2	AlphaFold	Q5BJZ4	1-354	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691915

Promoter ID:

EPDNEW_R2440

Type:

initiation region

Name:

Surf6_1

Description:

surfeit 6

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	5,452,197 - 5,452,257	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307382	AgrOrtholog
BioCyc Gene	G2FUF-50331	BioCyc
Ensembl Genes	ENSRNOG00000005031	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006699.5	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7381547	IMAGE-MGC_LOAD
InterPro	Rrp14/SURF6_C	UniProtKB/TrEMBL
	Surf6	UniProtKB/TrEMBL
KEGG Report	rno:303076	UniProtKB/TrEMBL
MGC_CLONE	MGC:109125	IMAGE-MGC_LOAD
NCBI Gene	Surf6	ENTREZGENE
PANTHER	Surf6	UniProtKB/TrEMBL
	SURFEIT LOCUS PROTEIN 6	UniProtKB/TrEMBL
Pfam	SURF6	UniProtKB/TrEMBL
PhenoGen	Surf6	PhenoGen
RatGTEx	ENSRNOG00000005031	RatGTEx
UniProt	F7F149	ENTREZGENE, UniProtKB/TrEMBL
	Q5BJZ4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Surf6	surfeit 6	LOC108352178	surfeit locus protein 6-like	Data merged from RGD:11365920	737654	PROVISIONAL
2016-08-02	LOC108352178	surfeit locus protein 6-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-10-23	Surf6	surfeit 6	Surf6	surfeit gene 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Surf6	surfeit gene 6	Surf6_predicted	surfeit gene 6 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Surf6_predicted	surfeit gene 6 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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