Wdfy2 (WD repeat and FYVE domain containing 2) - Rat Genome Database

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Gene: Wdfy2 (WD repeat and FYVE domain containing 2) Rattus norvegicus
Analyze
Symbol: Wdfy2
Name: WD repeat and FYVE domain containing 2
RGD ID: 1307337
Description: Predicted to enable zinc ion binding activity. Predicted to be involved in positive regulation of fat cell differentiation and positive regulation of protein phosphorylation. Predicted to be located in cytoplasm and vesicle. Predicted to be active in early endosome. Orthologous to human WDFY2 (WD repeat and FYVE domain containing 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC305956; WD repeat and FYVE domain-containing protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81541,259,840 - 41,385,549 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1541,259,884 - 41,385,549 (+)EnsemblGRCr8
mRatBN7.21537,083,842 - 37,209,559 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1537,042,987 - 37,209,304 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1538,949,935 - 39,074,627 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01540,100,765 - 40,225,433 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01538,544,497 - 38,669,945 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01546,008,613 - 46,134,319 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1546,008,613 - 46,134,064 (+)Ensemblrn6Rnor6.0
Rnor_5.01549,774,557 - 49,900,263 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41542,095,912 - 42,222,222 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1536,769,721 - 36,895,015 (+)NCBICelera
RGSC_v3.11542,111,625 - 42,234,122 (+)NCBI
Cytogenetic Map15p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA,ISO)
early endosome  (IBA,IEA,ISO)
endosome  (IEA)
vesicle  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16792529   PMID:17313651   PMID:18388859  


Genomics

Comparative Map Data
Wdfy2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81541,259,840 - 41,385,549 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1541,259,884 - 41,385,549 (+)EnsemblGRCr8
mRatBN7.21537,083,842 - 37,209,559 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1537,042,987 - 37,209,304 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1538,949,935 - 39,074,627 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01540,100,765 - 40,225,433 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01538,544,497 - 38,669,945 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01546,008,613 - 46,134,319 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1546,008,613 - 46,134,064 (+)Ensemblrn6Rnor6.0
Rnor_5.01549,774,557 - 49,900,263 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41542,095,912 - 42,222,222 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1536,769,721 - 36,895,015 (+)NCBICelera
RGSC_v3.11542,111,625 - 42,234,122 (+)NCBI
Cytogenetic Map15p12NCBI
WDFY2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381351,584,462 - 51,767,709 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1351,584,455 - 51,767,709 (+)Ensemblhg38GRCh38
GRCh371352,158,598 - 52,341,845 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361351,056,485 - 51,234,172 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341351,056,644 - 51,232,133NCBI
Celera1333,207,683 - 33,385,373 (+)NCBICelera
Cytogenetic Map13q14.3NCBI
HuRef1332,948,174 - 33,125,829 (+)NCBIHuRef
CHM1_11352,126,054 - 52,303,714 (+)NCBICHM1_1
T2T-CHM13v2.01350,799,394 - 50,982,622 (+)NCBIT2T-CHM13v2.0
Wdfy2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391463,075,110 - 63,198,958 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1463,075,127 - 63,198,958 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381462,837,661 - 62,961,509 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1462,837,678 - 62,961,509 (+)Ensemblmm10GRCm38
MGSCv371463,456,527 - 63,575,723 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361461,791,788 - 61,910,613 (+)NCBIMGSCv36mm8
Celera1460,596,380 - 60,715,100 (+)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.23NCBI
Wdfy2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554314,912,954 - 5,060,304 (+)Ensembl
ChiLan1.0NW_0049554314,809,405 - 5,086,647 (+)NCBIChiLan1.0ChiLan1.0
WDFY2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21453,012,653 - 53,199,203 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11351,656,791 - 51,843,328 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01332,714,088 - 32,896,885 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11351,458,583 - 51,636,052 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1351,535,071 - 51,636,052 (+)EnsemblpanPan2panpan1.1
WDFY2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.122304,250 - 467,909 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl22304,884 - 428,223 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha22339,809 - 501,888 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.022287,185 - 449,561 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl22287,189 - 449,149 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.122208,347 - 370,765 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.022257,949 - 420,217 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.022275,964 - 438,418 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Wdfy2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945160,798,259 - 161,043,209 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365654,375,462 - 4,520,691 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365654,375,012 - 4,527,259 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDFY2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1116,092,698 - 16,195,134 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11116,086,872 - 16,272,513 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21116,400,193 - 16,409,752 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WDFY2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1329,462,390 - 29,644,021 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl329,462,836 - 29,640,806 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605714,172,564 - 14,363,230 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdfy2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247482,412,808 - 2,612,437 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247482,412,808 - 2,748,661 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Wdfy2
391 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1240
Count of miRNA genes:353
Interacting mature miRNAs:506
Transcripts:ENSRNOT00000066864
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

Markers in Region
D15Rat8  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81541,315,931 - 41,316,175 (+)Marker Load Pipeline
mRatBN7.21537,139,936 - 37,140,182 (+)MAPPERmRatBN7.2
Rnor_6.01546,064,706 - 46,064,949NCBIRnor6.0
Rnor_5.01549,830,650 - 49,830,893UniSTSRnor5.0
RGSC_v3.41542,152,319 - 42,152,730RGDRGSC3.4
RGSC_v3.41542,152,364 - 42,152,607UniSTSRGSC3.4
Celera1536,825,818 - 36,826,061UniSTS
RGSC_v3.11542,168,064 - 42,168,307RGD
RH 3.4 Map15206.8UniSTS
RH 3.4 Map15206.8RGD
RH 2.0 Map15237.7RGD
SHRSP x BN Map1530.0999RGD
Cytogenetic Map15p12UniSTS
D15Got244  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21537,156,989 - 37,157,182 (+)MAPPERmRatBN7.2
Rnor_6.01546,081,754 - 46,081,944NCBIRnor6.0
Rnor_5.01549,847,698 - 49,847,888UniSTSRnor5.0
RGSC_v3.41542,169,412 - 42,169,602UniSTSRGSC3.4
Celera1536,842,866 - 36,843,056UniSTS
Cytogenetic Map15p12UniSTS
RH143178  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21537,205,476 - 37,205,660 (+)MAPPERmRatBN7.2
Rnor_6.01546,130,237 - 46,130,420NCBIRnor6.0
Rnor_5.01549,896,181 - 49,896,364UniSTSRnor5.0
RGSC_v3.41542,218,395 - 42,218,578UniSTSRGSC3.4
Celera1536,891,188 - 36,891,371UniSTS
RH 3.4 Map15271.0UniSTS
Cytogenetic Map15p12UniSTS
AI535484  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21537,207,284 - 37,207,491 (+)MAPPERmRatBN7.2
Rnor_6.01546,132,045 - 46,132,251NCBIRnor6.0
Rnor_5.01549,897,989 - 49,898,195UniSTSRnor5.0
RGSC_v3.41542,220,203 - 42,220,409UniSTSRGSC3.4
Celera1536,892,996 - 36,893,202UniSTS
RH 3.4 Map15261.2UniSTS
Cytogenetic Map15p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000066864   ⟹   ENSRNOP00000061576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1541,259,884 - 41,385,548 (+)Ensembl
mRatBN7.2 Ensembl1537,083,842 - 37,209,304 (+)Ensembl
Rnor_6.0 Ensembl1546,008,613 - 46,134,064 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080537   ⟹   ENSRNOP00000074718
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1541,297,841 - 41,385,549 (+)Ensembl
mRatBN7.2 Ensembl1537,042,987 - 37,209,304 (+)Ensembl
Rnor_6.0 Ensembl1546,008,636 - 46,129,571 (+)Ensembl
RefSeq Acc Id: NM_001107269   ⟹   NP_001100739
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,259,840 - 41,385,294 (+)NCBI
mRatBN7.21537,083,842 - 37,209,304 (+)NCBI
Rnor_6.01546,008,613 - 46,134,064 (+)NCBI
Rnor_5.01549,774,557 - 49,900,263 (+)NCBI
RGSC_v3.41542,095,912 - 42,222,222 (+)RGD
Celera1536,769,721 - 36,895,015 (+)RGD
Sequence:
RefSeq Acc Id: NM_001415102   ⟹   NP_001402031
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,259,901 - 41,385,549 (+)NCBI
mRatBN7.21537,083,903 - 37,209,559 (+)NCBI
RefSeq Acc Id: XM_039093325   ⟹   XP_038949253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,298,468 - 41,385,549 (+)NCBI
mRatBN7.21537,122,450 - 37,209,559 (+)NCBI
RefSeq Acc Id: XM_039093327   ⟹   XP_038949255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,260,199 - 41,385,549 (+)NCBI
mRatBN7.21537,084,089 - 37,209,559 (+)NCBI
RefSeq Acc Id: XM_039093328   ⟹   XP_038949256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,324,086 - 41,385,549 (+)NCBI
mRatBN7.21537,148,094 - 37,209,559 (+)NCBI
RefSeq Acc Id: XM_063274283   ⟹   XP_063130353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,260,104 - 41,385,549 (+)NCBI
RefSeq Acc Id: NP_001100739   ⟸   NM_001107269
- Peptide Label: isoform 1
- UniProtKB: D4A0J0 (UniProtKB/TrEMBL),   A6K6E4 (UniProtKB/TrEMBL),   A6K6E5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074718   ⟸   ENSRNOT00000080537
Ensembl Acc Id: ENSRNOP00000061576   ⟸   ENSRNOT00000066864
RefSeq Acc Id: XP_038949255   ⟸   XM_039093327
- Peptide Label: isoform X3
- UniProtKB: A6K6E6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949253   ⟸   XM_039093325
- Peptide Label: isoform X1
- UniProtKB: A6K6E5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038949256   ⟸   XM_039093328
- Peptide Label: isoform X4
RefSeq Acc Id: NP_001402031   ⟸   NM_001415102
- Peptide Label: isoform 2
- UniProtKB: A0A0G2K8S4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063130353   ⟸   XM_063274283
- Peptide Label: isoform X2
- UniProtKB: A6K6E5 (UniProtKB/TrEMBL)
Protein Domains
FYVE-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K8S4-F1-model_v2 AlphaFold A0A0G2K8S4 1-400 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699769
Promoter ID:EPDNEW_R10293
Type:initiation region
Name:Wdfy2_1
Description:WD repeat and FYVE domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01546,008,674 - 46,008,734EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307337 AgrOrtholog
BioCyc Gene G2FUF-13448 BioCyc
Ensembl Genes ENSRNOG00000010042 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000066864 ENTREZGENE
  ENSRNOT00000066864.3 UniProtKB/TrEMBL
  ENSRNOT00000080537 ENTREZGENE
  ENSRNOT00000080537.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep_reg UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
  WDFY1/WDFY2 UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene 305956 ENTREZGENE
PANTHER PTHR46189 UniProtKB/TrEMBL
  WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam FYVE UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Wdfy2 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010042 RatGTEx
SMART FYVE UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF57903 UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt A0A0G2K8S4 ENTREZGENE, UniProtKB/TrEMBL
  A6K6E4 ENTREZGENE, UniProtKB/TrEMBL
  A6K6E5 ENTREZGENE, UniProtKB/TrEMBL
  A6K6E6 ENTREZGENE, UniProtKB/TrEMBL
  D4A0J0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Wdfy2  WD repeat and FYVE domain containing 2   Wdfy2_predicted  WD repeat and FYVE domain containing 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Wdfy2_predicted  WD repeat and FYVE domain containing 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED