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Gene: Sacs (sacsin molecular chaperone) Rattus norvegicus

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Symbol:

Sacs

Name:

sacsin molecular chaperone

RGD ID:

1307281

Description:

Predicted to enable several functions, including Hsp70 protein binding activity; low-density lipoprotein particle receptor binding activity; and proteasome binding activity. Predicted to be involved in negative regulation of inclusion body assembly. Predicted to be located in mitochondrion and nucleus. Human ortholog(s) of this gene implicated in Charlevoix-Saguenay spastic ataxia. Orthologous to human SACS (sacsin molecular chaperone); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4-amino-2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC290301; LOC305940; RGD1305416; sacsin; similar to RIKEN cDNA E130115J16; spastic ataxia of Charlevoix-Saguenay (sacsin)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SACS (sacsin molecular chaperone)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Sacs (sacsin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sacs (sacsin molecular chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SACS (sacsin molecular chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SACS (sacsin molecular chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sacs (sacsin molecular chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SACS (sacsin molecular chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SACS (sacsin molecular chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sacs (sacsin molecular chaperone)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SRD5A3 (steroid 5 alpha-reductase 3)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	SACS (sacsin molecular chaperone)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Sacs (sacsin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sacs (sacsin molecular chaperone)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sacs	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sacs	Alliance	DIOPT (Ensembl Compara\|OrthoFinder)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	39,461,853 - 39,546,419 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	39,472,905 - 39,546,419 (+)	Ensembl				GRCr8
mRatBN7.2	15	35,285,783 - 35,370,335 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	35,285,782 - 35,370,335 (+)	Ensembl				mRatBN7.2
Rnor_6.0	15	41,448,078 - 41,530,412 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	41,448,064 - 41,530,398 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	45,255,280 - 45,338,141 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	40,297,202 - 40,344,605 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	34,984,356 - 35,069,050 (+)	NCBI		Celera
RGSC_v3.1	15	40,315,190 - 40,359,066 (+)	NCBI
Cytogenetic Map	15	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

ATAXIA, SPASTIC, CHILDHOOD-ONSET, AUTOSOMAL RECESSIVE, WITH OPTIC ATROPHY AND MENTAL RETARDATION (ISO)

autosomal recessive limb-girdle muscular dystrophy (ISO)

autosomal recessive limb-girdle muscular dystrophy type 2C (ISO)

autosomal recessive limb-girdle muscular dystrophy type 2D (ISO)

Charcot-Marie-Tooth disease X-linked dominant 1 (ISO)

Charlevoix-Saguenay spastic ataxia (ISO,ISS)

genetic disease (ISO)

hereditary ataxia (ISO)

hereditary spastic paraplegia (ISO)

myoepithelioma (ISO)

paraplegia (ISO)

progressive myoclonus epilepsy (ISO)

schizophrenia (ISO)

spastic ataxia (ISO)

spastic ataxia 3 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1-nitropyrene (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,4'-trichlorobiphenyl (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

4-hydroxyphenyl retinamide (ISO)

7,12-dimethyltetraphene (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

cantharidin (ISO)

CGP 52608 (ISO)

choline (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

coumarin (ISO)

coumestrol (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

DDE (ISO)

DDT (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dimethylarsinic acid (ISO)

elemental selenium (ISO)

folic acid (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

indole-3-methanol (EXP)

indometacin (ISO)

L-methionine (ISO)

lead(0) (ISO)

maneb (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methylarsonic acid (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodiethylamine (EXP)

nickel sulfate (ISO)

nilotinib (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (ISO)

PCB138 (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

permethrin (EXP)

pirinixic acid (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (EXP)

selenium atom (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

succimer (ISO)

tamibarotene (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (EXP,ISO)

vitamin E (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of inclusion body assembly (IEA,ISO)

Cellular Component

cytoplasm (IEA,ISO)

mitochondrion (IEA,ISO)

nucleus (IEA,ISO)

Molecular Function

Hsp70 protein binding (IBA,IEA,ISO)

identical protein binding (IEA,ISO)

low-density lipoprotein particle receptor binding (IEA,ISO)

proteasome binding (IEA,ISO)

protein-folding chaperone binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15632090	PMID:19208651	PMID:19666135	PMID:21700703	PMID:23250129	PMID:31505169	PMID:35053415

Genomics

Comparative Map Data

Sacs
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	39,461,853 - 39,546,419 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	39,472,905 - 39,546,419 (+)	Ensembl				GRCr8
mRatBN7.2	15	35,285,783 - 35,370,335 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	35,285,782 - 35,370,335 (+)	Ensembl				mRatBN7.2
Rnor_6.0	15	41,448,078 - 41,530,412 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	41,448,064 - 41,530,398 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	45,255,280 - 45,338,141 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	40,297,202 - 40,344,605 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	34,984,356 - 35,069,050 (+)	NCBI		Celera
RGSC_v3.1	15	40,315,190 - 40,359,066 (+)	NCBI
Cytogenetic Map	15	p12	NCBI

SACS
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	23,328,830 - 23,433,702 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	13	23,288,689 - 23,433,763 (-)	Ensembl			hg38	GRCh38
GRCh37	13	23,902,969 - 24,007,841 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	22,800,966 - 22,840,626 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	13	22,800,966 - 22,840,626	NCBI
Celera	13	4,965,968 - 5,070,846 (-)	NCBI		Celera
Cytogenetic Map	13	q12.12	NCBI
HuRef	13	4,715,591 - 4,820,305 (-)	NCBI		HuRef
CHM1_1	13	23,871,558 - 23,976,445 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	13	22,535,642 - 22,640,549 (-)	NCBI		T2T-CHM13v2.0

Sacs
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	61,375,870 - 61,478,142 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	61,375,906 - 61,478,144 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	61,138,421 - 61,240,693 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	61,138,457 - 61,240,695 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	61,757,294 - 61,859,530 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	60,092,567 - 60,194,803 (+)	NCBI		MGSCv36	mm8
Celera	14	58,906,142 - 59,008,250 (+)	NCBI		Celera
Cytogenetic Map	14	D1	NCBI
cM Map	14	32.13	NCBI

Sacs
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955497	3,706,882 - 3,754,663 (-)	Ensembl
ChiLan1.0	NW_004955497	3,701,515 - 3,752,627 (-)	NCBI	ChiLan1.0	ChiLan1.0

SACS
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	14	22,945,914 - 23,049,302 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	13	14,052,946 - 14,156,634 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	13	4,642,078 - 4,745,453 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	13	22,936,013 - 22,978,366 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	13	22,937,320 - 22,982,553 (-)	Ensembl			panPan2	panpan1.1

SACS
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	15,207,959 - 15,297,483 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	15,207,839 - 15,296,078 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	15,291,066 - 15,380,653 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	15,344,721 - 15,434,496 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	15,344,724 - 15,433,719 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	15,219,819 - 15,309,238 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	15,221,010 - 15,310,645 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	15,277,258 - 15,366,849 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sacs
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	117,374,760 - 117,516,578 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936688	1,987,054 - 2,079,173 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936688	1,987,075 - 2,079,148 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SACS
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	2,382,906 - 2,442,316 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	11	2,382,406 - 2,455,756 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	1,722,558 - 1,743,861 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SACS
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	3,217,640 - 3,323,801 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	3,216,397 - 3,323,754 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666057	41,209,226 - 41,315,831 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sacs
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624776	14,290,198 - 14,460,046 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624776	14,290,186 - 14,395,303 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Sacs
787 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	53
Count of miRNA genes:	46
Interacting mature miRNAs:	49
Transcripts:	ENSRNOT00000019551, ENSRNOT00000038665, ENSRNOT00000075479
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	17362897	73690657	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	42356671	Rat
10755503	Bp391	Blood pressure QTL 391	2.37		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	20248600	37896129	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	306329	45306329	Rat
2293686	Bmd36	Bone mineral density QTL 36	7.4	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	15	33611058	71477291	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	12496141	65205939	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
2293691	Bmd37	Bone mineral density QTL 37	6.6	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	15	33611058	71477291	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	11111142	56111142	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
631273	Lecl2	Lens clarity QTL 2		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	15	10596089	55596089	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
731170	Pur3	Proteinuria QTL 3	2.3	0.0005	urine protein amount (VT:0005160)	urine protein excretion rate (CMO:0000759)	15	1	41686771	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat
152025253	Hrtrt24	Heart rate QTL 24	3.82		heart pumping trait (VT:2000009)		15	27885774	86257085	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	22117933	67117933	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	19856566	46187442	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	34054139	79054139	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat

Markers in Region

D15Hmgc1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	35,337,101 - 35,337,216 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	41,497,179 - 41,497,293	NCBI	Rnor6.0
Rnor_5.0	15	45,304,908 - 45,305,022	UniSTS	Rnor5.0
RGSC_v3.4	15	40,311,375 - 40,311,490	RGD	RGSC3.4
RGSC_v3.4	15	40,311,376 - 40,311,490	UniSTS	RGSC3.4
Celera	15	35,035,815 - 35,035,929	UniSTS
RH 3.4 Map	15	227.8	UniSTS
RH 3.4 Map	15	227.8	RGD
Cytogenetic Map	15	p12	UniSTS

RH142830

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	35,354,510 - 35,354,680 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	41,514,588 - 41,514,757	NCBI	Rnor6.0
Rnor_5.0	15	45,322,317 - 45,322,486	UniSTS	Rnor5.0
RGSC_v3.4	15	40,328,785 - 40,328,954	UniSTS	RGSC3.4
Celera	15	35,053,226 - 35,053,395	UniSTS
RH 3.4 Map	15	230.3	UniSTS
Cytogenetic Map	15	p12	UniSTS

AW524447

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	35,369,907 - 35,370,003 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	41,529,985 - 41,530,080	NCBI	Rnor6.0
Rnor_5.0	15	45,337,714 - 45,337,809	UniSTS	Rnor5.0
RGSC_v3.4	15	40,344,181 - 40,344,276	UniSTS	RGSC3.4
Celera	15	35,068,623 - 35,068,718	UniSTS
RH 3.4 Map	15	231.3	UniSTS
Cytogenetic Map	15	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	164	91	90	59	92	59	6	355	192	11	143	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001427721	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221975	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252167	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008770792	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599898	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274275	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274276	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274278	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000019551 ⟹ ENSRNOP00000019551

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	39,472,905 - 39,546,419 (+)	Ensembl
mRatBN7.2 Ensembl	15	35,285,782 - 35,370,335 (+)	Ensembl
Rnor_6.0 Ensembl	15	41,448,064 - 41,530,398 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000098951 ⟹ ENSRNOP00000095452

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	39,500,646 - 39,546,178 (+)	Ensembl
mRatBN7.2 Ensembl	15	35,285,782 - 35,370,335 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000113056 ⟹ ENSRNOP00000095721

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	39,501,902 - 39,546,419 (+)	Ensembl
mRatBN7.2 Ensembl	15	35,325,872 - 35,370,335 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000168656 ⟹ ENSRNOP00000103011

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	39,472,905 - 39,546,178 (+)	Ensembl

RefSeq Acc Id:

NM_001427721 ⟹ NP_001414650

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,501,902 - 39,546,419 (+)	NCBI

RefSeq Acc Id:

XM_006252167 ⟹ XP_006252229

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,461,853 - 39,546,416 (+)	NCBI
mRatBN7.2	15	35,285,783 - 35,370,335 (+)	NCBI
Rnor_6.0	15	41,448,078 - 41,530,412 (+)	NCBI
Rnor_5.0	15	45,255,280 - 45,338,141 (+)	NCBI

Sequence:

show sequence

ACTGCCGCACTCTGCCGGTCCTGCGCTGAATGCAGTGGCGGTCACGCTGGGACTCGTTGTTGGT
ACAAAAGGCACACAAAGGGCAGGCGACCAGGTTGACGATGGCCACAGTGAGACTCTGAGGGTCC
TTCGGACTGCGTCTGGTCTAGGAACAGCTGTATCGGGTGTTGCGCCCCGCCAGAGCCGGGCGGC
CCAGTCGCCCCCGCAGCCGCTGCCGGTCCAGGCCGGTCTCTGGACAAGTGGACCACGGTCCTCA
GCATCCACACCCCCAGGGAAGACAGAACAGCTCTGGCATGTAGTGCCGCAGCGCACCGAGTCCC
CGAGATAAAGCCAAGATGCTAGTAGCTCCAGACCTGGGAGAAGTGCTCTCAACGGCAAGCATCT
TGTATCTCCTGAGATGAGGGTGGGCGGCATCTGCCCTCTGCAGTTCCAGCAAGGAATACAGAAG
AGCCAGAGAGGAGGAACACGTTAAGGTTGCCCCTGGAAAAAGCCCAAAACTGCCAGCCAGCTGA
TACTGGTTTGCTTTAAAAAGGCAACCTTATCAGATCAGAGCAGCATACAGAACACAGGAACAAA
ACACAATGTTTTCTGATGTCACACGGTGACAGATGCTGGGGAAGACTGGCTTTTCATCAGCCAG
GAAGAGCTTCGTTCAGAGTGCACATCGACAAGAAACACAGGAAGCACAAAGGACCCTTAAGCAG
AAGGAAGCGGGAACCGTCTATGGTTTGCAAGGACAACTGCTCCAGTGACCATGGGGACCGAGGA
GACTAGGTGGGTCCGCGTGACCGTGCTCCGCGGCTGCGTGGGCTGCAGGACCGTGGCGGTGCGG
GCCACCGCAACCGGGCGGGACCTCAAGGAGCGCATCTTCGCTGAGACCGGCTTCCCGGTGGCGG
AGCAGCGACTGTGGCGCGGAGACAGGGAGATACCTGATTGGATCAAGATTGGAGATCTGACTTC
TAAAACCTGTCTTTTTGTAAACCTTCAATCAAAAGGCTTAAAAGGGGGAGGTCGATTTGGTCAA
ACAACACCACCACTTGTCGATTTTCTCAAGGATATTTTAAGAAGATATCCAGAAGGAGGACAGA
TCCTTAAGGAATTAATTCAGAATGCAGAAGATGCTGGGGCCACAGAGGTTAAATTTTTATATGA
TGAAACACAATATGGAACGGAGACTCTTTGGTCAAAAGATATGGCGCAATATCAGGGGTCGGCT
CTCTATGTGTACAACAATGCGGTTTTCACCCCAGAGGACTGGCATGGCATTCAGGAAATAGCAA
GAAGCAGGAAAAAAGATGATCCCTTGAAGGTTGGAAGATTTGGAATTGGGTTTAATTCTGTCTA
CCATATAACAGATGTTCCTTGTATCTTTAGTGGTGACCAGATAGGAATGCTAGACCCTCATCAA
ACACTTTTTGGCCCCCACGAATCAGGCCAATGTTGGAATCTCAAAGATGACATCAAAGAAATAA
ATGAGCTTCCGGATCAGTTTGCACCGTTCATTGGTGTTTTTGGAAGCACCAAGGAAACCTTTAC
AAACGGCAGCTTCCCAGGGACGTTTTTCCGTTTCCCTCTGCGCTTACAACCTTCCCAGCTTAGC
AGCAATCTCTACACTAAGCAGAAGGTTCTGGAGTTGTTCGACTCTTTCCGGGCGGATGCAGACA
CAGTGCTGCTCTTCCTGAAGAGCGTGCAGGCTGTGTCTTTACATGTCCGAGAGGCCGATGGGAC
AGAAAAACTGGTCTTTAGAGTAACTGCTAGTGAGAATAAGACCCTGAAGCATGAACGGCCAAAT
TCTATTAAGATTCTGGGAACGGCTATAAGTAACTATTGTAAAAAGATCCCAAGCAACAGTGTAA
CCTGTGTAACATATCATATAAACATAGCTCTAGAGGATGAGAGTACAAAAGATGCCCAGAAGAC
ATCTTGGTTGGTATGTAACAGTGTGGGTGGGCGGGGCATTAGTAGTAAACTGGATTCTTTGGCT
GATGAGTTGAAATTTGTCCCAATCATTGGTCTAGCCATGTCTTTATCAGGCAGGGATGAAGAGA
ATGGAGCAACATCCGATTTCTCAGGAAAAGCATTTTGTTTTCTTCCCTTGCCTCCTGGTGAGGA
AAGCAGAACAGGGCTTCCAGTTCATATCAGTGGCTTCTTTGGCCTGACTGACAACCGCAGGAGC
ATAAAATGGAGAGAGCTGGACCAATGGAGGGACCCTGCGGCCTTGTGGAATCAATTTCTTATTG
TGAATGTTGTTCCCAAAGCTTATGCTACTCTCATCCTGGATTCAATAAAACGCCTGGAGACAGA
GAAGAGCTCTGATTTCCCCTTATCAGTGGACGCCATCTACAAACTTTGGCCTGAGGCCAGCAAG
GTCAAGGCACACTGGCATCCAGTGTTGGGTCCTCTGTTTAGCGAACTGTTCCAGCATGCTGTCA
TTTACTCAGTCGGTGGCGAGTGGGTGAAGCTGGAGCAGGTGCACTTCTCAGAACTCGATGAAAG
TTTAGAATCCACACAGTCTGTGCTCAACTACCTCCAGCGCTCAGGGAAGCAGATTGCCAGGGTA
CCGGGGAACTTGGCTGCTGCTGTTCAGCTCAGTGCAGCCTCTGCCACCTCCACTGCATCTCCTG
TGAGGAAGGTGACGCCTGTGTGGGTGCGGCAGGTGCTGAGGAAGTGTGCCCACCTGGGCAGTGC
CGAAGAAAAGCTCCATCTTCTGGAGTTTGTGCTTTCTGACCAAGCCTACAGTGAGCTGCTTGGC
CTGGAGCTGCTGCCTTTACAGAGTGGGGCTTTTGTCCCCTTCTCCTCATCTGTCTCTGACCAAG
ATGTTGTTTACATCACCTCAGAAGAATTCCCAAGGTCCCTTTTCCCAGGTCTTGAAGCAAGACT
TATTTTGGAGAACTTGAAGCCTCATCTTCTAGCTGCTTTAAAAGAAGCTGCCCAGACCCGAGCA
CAGCAGCTTCTCTGGGGATACTCAGGAAGACCATGTACTCAGCTGCAGCTTCTAAATCCAGAGC
GATTTGCACGTCTTATTAAAGAAGTAATGAATACATTCTGGCCTGGTCGAGAGTTGGTGGTTCA
GTGGTATCCATTGAGTGAAGACAAACATCACCCGTCCATTTCATGGCTTAAGATGGTTTGGAAG
AATCTCTACATACATTTCTCAGAGGATTTGACTTTATTTGATGAGATGCCACTTATCCCCAGAA
CTCCACTGGATGCAGATCAGACGTGTGTGGAACTCATTAGACTCAGGGTCCCATCAGTAGTCAT
TTTAGATGATGAAACTGAAGCTCAGCTTCCGGAATTCCTAGCAGACATTGTACAAAAACTTGGA
GGCATTGTCCTGAAAAGATTAGATACCTCTCTTCAGCATCCGCTTGTTAAAAAATACATTCATT
CCCCACTGCCGAGTGCTATTTTGCAGATAATGGAGAAGATACCACTGCAGAAGTTGTGTAATCA
AATAGCATCATTACTTCCAACCCACAAAGATGCTCTAAGGAAGTTTTTGGCCAGCTTAACTGAT
ACCAGTGAAAAAGAGAAAAGAATAATTCAAGAATTGACAATATTCAAGAGAATTAATCATTCAT
CTGATCAAGGAATTTCCTCTTACACAAAACTAAAAGGATGTAAAGTTTTGGATCATACCGCCAA
GCTTCCAACAGAACTACGGCTCTCAGTTTCAGTAATAGATAGTAGTGATGAAGCCACCATTCGT
TTGGCAAACATGCTGAAAATTGAAAAGTTAAAGACTACAAGCTGTTTAAAGTTTGTTTTAAAAG
ATATTGAAAATGCATTTTATACACAGGAAGAGGTAACACGGCTTATGCTGTGGATCCTTGAGAA
TCTATCTTCTCTTAAAAATGAGAATCCAAGTGTGCTTGATTGGTTAATGCCACTAAAATTCATT
CATATGTCACAGGAGCATGTGGTAGCAGCCAGTGACCTCTTTGATCCTGATATAGAAGTCCTAA
GGGATCTCTTTTATAACGAAGAGGAAGCCTGTTTCCCTCCTGCAGTTTTTACCTCACCAGATAT
CCTTCACTCTTTGAGACAGATTGGCTTAAAAAATGAAGCCAGCCTAAAAGAGAAAGATGTCGTA
CAGGTGGCCAAAAAAATTGAAGCTTTACAGGTCAGTTCCTGTCAGAATCAGGATGTTCTCCTGA
AGAAAGCCAAAACACTCTTGCTGGTCTTGAATAAAAACCATACACTCTTGCAGTCTTCTGAGGG
GAAGATGGCATTGAAGAAAATAAAATGGGTTCCAGCCTGCAAGGAAAGACCCCCAAATTATCCA
GGTTCTTTAGTCTGGAAAGGGGATCTCTGTAATCTTTGTGCACCTCCAGATATGTGTGATGCAG
CTCACGCAGTTCTAGTGGGCTCCTCACTTCCTCTTGTTGAGAGTGCCCATGTGAGCTTGGAGAA
GACCCTCGGCATCTTCACGAAGCCTACCATCAGTGCTGTCTTAAAACACTTTAAAATTGTTGTT
GACTGGTATACTTCAAAAACCTTTAGTGACGAAGATTACTATCAGTTCCAACATATTTTGCTTG
AAATTTATGGGTTCATGCATGATCATCTGAGTGAAGGGAAGGATTCTTTTAAAGCCTTGAAATA
CCCCTGGGTTTGGACAGGCAAAAACTTTTGTCCTCTTGCCCAGGCTGTGATAAAGCCAATCCAT
GATCTGGACCTTCAGCCTTATTTATATAATGTGCCTAAAACCATGGCAAAATTCCACCAGCTGT
TCAAGGCTTGTGGCTCAATAGAAGAGTTGACATCAGATCATATTTCCATGGTCATTCAGAAAGT
TTATCTCAAAAGTGACCAGGAGTTGAGTGAGGAAGAAAGTAAGCAAAATCTTCATCTCATGTTG
AATATCATGAGATGGCTGTACAGCAATCAGATCCCAGCAAGCCCTAATACCCCAGTTCCTATTT
ATCACAGCAAAAATCCTTCCAAACTTGTCATGAAGCCAATTCATGAGTGCTGTTATTGTGATAT
CAAAGTTGATGACCTTAATGACTTGCTTGAAGACTCAGTGGAACCAATCATTTTGGTACATGAG
GACATACCCATGAAAACTGCAGAGTGGCTAAAAGTTCCGTGCCTTAGTACAAGACTGATCAATC
CTGAAAACATGGGGTTTGAGCAGTCAGGGCAAAGAGAGCCTCTTACTGTAAGGATTAAAAACAT
TTTGGAAGAATACCCTTCAGTGTCAGATATTTTTAAAGAGCTGCTTCAAAATGCTGATGATGCG
AATGCCACCGAATGCAGCTTCATGATTGATATGAGAAGAAATATGGACATAAGGGAAAATCTCC
TAGACCCAGGGATGGCAGCTTGTCATGGACCTGCTCTGTGGTCATTCAACAATTCTGAATTCTC
AGATTCAGATTTCATAAACATTACCAGGTTAGGAGAATCTTTAAAAAGGGGAGAAGTTGACAAG
GTTGGAAAATTTGGTCTTGGTTTTAATTCTGTGTACCACATTACTGACATTCCCATCATTATGA
GCCGAGAATTTATGATAATGTTTGATCCAAACATAAATCACATCAGTAAACACATTAAAGATAG
ATCTAATCCTGGAATCAAAATTAATTGGAGTAAACAGCAGAAAAGACTTAGGAAATTCCCCAAT
CAGTTCAAACCATTTATAGATGTATTTGGTTGTCAGCTGCCTTTGGCCGTAGAAGCTCCTTACA
GCTACAATGGGACTCTCTTCCGACTGTCCTTTAGAACGCAGCAGGAAGCAAAAGTGAGTGAAGT
TAGCAGTACTTGTTATAACACTGCGGATATTTACTCCCTGGTGGATGAATTTAGTCTTTGTGGG
CACAGACTTATCATTTTTACTCAGAGTGTAAACTCAATGTATTTGAAATACTTGAAAATTGAAG
AAACCAATCCTACCTTAGCACAAGATACAATAATAATTAAGAAAAAAGCTTGCCCCTCCAAAGC
ATTGAATGCACCAGTTTTAAGTGTTTTAAAAGAAGCTGCTAAACTCATGAAGACTTGTAGCAGC
AGCAACAAGAAGCTTCCCACTGATGTACCAAAGTCATCTTGCATTCTTCAGATCACAGTTGAGG
AATTTCACCATGTGTTCAGGAGGATTGCTGACTTACAGTCACCACTGTTCAGAGGTCCAGATGA
TGACCCAGCTACTCTCTTTGAAATGGCTAAGTCTGGCCAATCAAAAAAGCCATCAGATGAGTTG
CCACAAAAGACAGTAGATTGTACCACATGGCTTATATGCACATGCATGGACACAGGAGAAGCTC
TCAAGTTTTCTTTGAATGAAAGTGGAAGAAGATTAGGGCTGGTTCCTTGTGGGGCAGTAGGAGT
TCTTTTGCATGAAACCCAGGAGCAGAAGTGGACTGTGAAACCACATATAGGAGAGGTGTTCTGC
TATTTACCTTTACGAATAAAAACAGGGTTGCCAATTCACATCAATGGGTGCTTTGCTGTTACTT
CAAATAGGAAAGAAATCTGGAAGACAGATACAAAAGGTCGATGGAATACCACTTTCATGAGGCA
CGTCATTGTGAAAGCTTACTTACAAGCACTCAGTGTTTTACGGGACCTGGCCATTAGCGGTGAG
CTGATTGATTATACTTACTATGCTGTGTGGCCTGATCCTGACGTAGTTCATGATGACTTCTCTG
TGATCTGTCAAGGATTTTATGAAGATATAGCTCATGGGAAGGGGAAGGACCTGACCAGAGTCTT
CTCTGATGGATCTATGTGGGTTTCCATGAAGAATGTGAGATTTCTAGATGACTCTATTCTTCAA
AGGAAAGATGTTGGCTCAGCAGCCTTCAAGATATTCCTGAAGTACCTCAAGAAGACAGGCTCCA
AAAACCTCTGTGCTGTTGAGCTTCCTTCTTCGGTAAAAGTAGGATTTGAAGAGGCTGGCTGCAA
ACAGATACTGCTAGAAAATACATTTTCAGAGAAACAGTTCTTTTCAGAAGTCTTCTTTCCTAAT
ATTCAGGAAATCGAAGCAGAACTTAGAGATCCTCTGATGAATTTTGTCTTAAATGAGAAACTTG
ATGAGTTCTCAGGAATTCTTCGTGTTACCCCTTGTGTCCCTTGCTCCTTGGAAGGCCATCCTTT
GGTTTTGCCTTCAAGATTGATCCATCCTGAAGGACGAGTTGCAAAGTTATTTGATATTAAAGAT
GGGAGATTCCCTTATGGGTCCACACAGGATTACCTCAATCCTATTATTTTGATCAAGCTCGTTC
AGTTAGGCATGGCAAAAGATGATATTTTGTGGGATGACATGCTAGAGCGTGCAGAGTCCGTAGC
TGAGATTAATAAAAGTGACCATGCTGCCGCCTGCTTAAGGAGTAGTATTCTACTAAGCCTCATT
GATGAGAAGCTAAAAATAAGGGATCCTAGAGCAAAGGATTTTGCTGCAAAATACCAAACAATTC
CCTTCCTCCCATTTCTGACAAAGCCAGCGGGTTTTTCTTTAGAGTGGAAAGGGAACAGTTTTAA
GCCTGAAACCATGTTTGCAGCAACTGACCTTTACACTGCTGAATATCAAGATATAGTCTGTCTT
TTGCAACCAATTCTCAATGAAAATTCCCATTCCTTTAGAGGCTGTGGTTCAGTGTCATTGGCTG
TTAAAGAGTTTTTGGGTTTGCTAAAGAAGCCAACAGTTGATCTGGTAATAAACCAGTTGAAGCA
AGTTGCAAAATCAGTTGATGATGGTATTACATTGTACCAGGAAAATATCACCAATGCTTGCTAC
AAGTACCTCCATGAAGCAATATTGCAAAATGAAATGGCCAAGGCAACAATTATTGAAAAGCTAA
AACCATTTTGTTTCATTCTGGTTGAGAATGTATATGTTGAGTCAGAAAAGGTTTCTTTTCATTT
GAACTTTGAAGCAGCGCCATACCTTTATCAGTTACCTAACAAGTATAAAAATAATTTCCGGGAG
CTTTTTGAAAGTGTGGGTGTGCGGCAGTCATTTACTGTTGAAGATTTTGCCTTAGTCTTGGAGT
CTATTGATCAAGAAAGAGGAAAAAAACAAATAACAGAAGAGAATTTTCAGCTTTGCCGACGAAT
AATCAGTGAAGGAATCTGGAGTCTCATCAGAGAAAAGAGACAAGAATTCTGTGAGAAAAATTAT
GGTAAAATATTACTGCCGGATACTAATCTGCTGCTGCTCCCTGCTAAGTCATTATGCTACAATG
ACTGTCCCTGGATAAAAGTAAAGGATTCTTCTGTTAAGTATTGCCATGCCGACATACCCCGGGA
AGTAGCTGTAAAACTAGGTGCAATACCAAAGAGACATAAAGCCTTAGAAAGATACGCATCCAAC
ATCTGTTTCACAGCTCCAGGTACAGAATTCGGGCAGAAAGAAAAACTGACCAGCAGAATTAAGA
GCATTCTCAATGCCTATCCTTCAGAAAAGGAAATGCTGAAAGAGCTTCTTCAGAATGCTGATGA
TGCGAAGGCCACGGAGATCTGCTTTGTGTTTGATCCTAGACAGCATCCTGTTGACCGAATATTT
GATGATAAGTGGGCCCCACTGCAAGGGCCAGCACTGTGTGTTTACAATAACCAGCCATTTACAG
AAGATGATGTTAGAGGAATTCAGAACCTTGGGAAAGGCACCAAAGAAGGAAACCCTTGCAAAAC
AGGACAATATGGAATTGGGTTCAATTCCGTGTACCACATTACAGACTGCCCTTCTTTTATTTCT
GGCAATGACATCCTGTGTATTTTTGATCCCCATGCCAGATATGCACCAGGAGCCACATCAGTTA
GCCCTGGACGAATGTTTAGAGATTTGGATGCAGACTTTAGAACCCAGTTCTCAGATGTTCTAGA
TCTTTACTTGGGAAACCACTTTAAACTGGACAATTGTACAATGTTTAGATTTCCTCTGCGTAAT
GCAGAAATGGCACAAGTTTCAGAAATTTCCTCAGTTCCATCATCAGACAGAATGGTCCAGAATC
TTTTGGACAAATTACGGTCTGATGGGGCAGAACTTCTAATGTTTCTCAACCACATGGAAAAAAT
ATCTATTTGTGAAATAGATAAGGCCACAGGAGGTCTGAATGTGCTCTATTCAGTAAAAGGCAAG
ATCACTGATGGAGACCGGTTGAAGAGGAAGCAGTTCCATGCCTCTGTAATTGACAGCGTTACTA
AAAAGAGACAGCTCAAGGACATACCAGTCCAACAGATAACCTACACCATGGATACTGAGGATTC
TGAAGGGAATCTGACCACGTGGCTCATCTGTAATAGATCAGGTTTTTCAAGTATGGACAAAGTA
TCCAAGAGTGTTATATCGGCTCACAGGAACCAAGATATCACCCTCTTCCCACGTGGTGGAGTCG
CTGCCTGCATTACTCACAATTATAAAAAGCCCCACCGAGCCTTCTGCTTTCTGCCTCTCTCTTT
GGAGACAGGGCTGCCATTTCATGTGAATGGCCATTTTGCTCTAGATTCAGCCAGAAGAAACTTG
TGGCGTGATGATAATGGAGTTGGTGTCCGCAGTGACTGGAACAATAGTTTAATGACAGCCTTAA
TAGCGCCTGCATATGTTGAATTACTAATCCAGTTAAAAAAACGGTATTTCCCTGGTTCTGACCC
AACATTATCAGTTTTACAGAACACACCCATTCATGTTGTAAAGGACACATTAAAGAAGTTCCTG
TCCTTCTTTCCAGTTAACAGGCTGGATCTGCAGCCGGATCTATATTGCTTAGTGAAAGCTCTTT
ACAGTTGCATTCATGAAGACATGAAACGTCTTTTACCTGTTGTTCGGGCTCCAAATATTGATGG
CTCTGATTTGCATTCTGCAGTCATAATTACTTGGATCAATATGTCTACTTCAAATAAAACTAAA
CCATTTTTTGATAACTTGCTACAGGATGAATTACAGCACCTTAAAAATGCCGATTATAACATCA
CAACTCGCAAAACAGTTGCAGAGAATGTCTACAGACTGAAGCACCTGCTTTTAGAAATTGGTTT
CAACTTGGTTTATAACTGTGATGAAACTGCTAACCTTTACCACTGCCTTGTAGATGCGGCTATC
CCCGTTAGCTATGTGACTCCTGCGGATGTTAGGTCCTTCTTAATGACATTCTCTTCTCCCGATA
CCAACTGCCATATTGGGAAGCTGCCTTGTCGTCTTCAGCAAACCAACTTAAAACTTTTTCACAG
TTTAAAACTTTTAGTTGATTACTGTTTTAAAGATGCTGAAGAAAGTGAGTTTGAAGTTGAGGGA
CTGCCCCTGCTCATTACACTGGACAGTGTCTTGCAGATTTTTGATGGTAAACGACCCAAGTTTC
TCACTACATACCATGAATTAATCCCATCACGTAAAGACTTGTTTATGAACACCTTATACTTGAA
ATACAGTAGTGTGTTGTTGAACTGCAAAGTTGCAAAAGTGTTCGACATTTCCAGCTTTGCTGAC
TTACTCTCTTCTGTGTTGCCTCGTGAGTATAAGACCAAGAACTGTGCAAAGTGGAAAGACAATT
TTGCCAGTGAGTCTTGGCTTAAGAATGCATGGCACTTTATCAGCGAATCAGTAAGTGTGACAGA
TGATCAGGAAGAACCAAAGCCAGCGTTTGATGTCATTGTTGACATCCTGAAAGACTGGGCATTG
CTTCCAGGAACAAAGTTCACTGTGTCAGCCAGCCAGCTTGTGGTTCCGGAGGGGGATGTGCTGA
TCCCCCTGAGCCTCATGCACATTGCCGTGTTCCCCAATGCTCAGAGTGACAAGGTTTTTCACGC
TCTGATGAAAGCAGGCTGTATTCAGCTGGCCTTGAACAAAATCTGCTCTAAAGACAGTGCATTA
GTCCCTTTGTTGTCATGCCACACAGCAAACATAGATAGCCCTGCAAGCATCTTGAAAGCTGTAC
ATTATATGGTTCAGACTTCAACATTTAGAACTGAAAAACTAGTAGAAAATGACTTTGAAGCACT
TTTGATGTATTTCAACTGTAATTTGAGTCACCTGATGTCCCAGGATGACCTAAAAATTTTAAAG
TCCCTTCCATGCTACAAATCCATCAGTGGCCGCTATATGAGCATTGCAAAATTTGGAACGTGCT
ATGTGCTTACCAAAAGTATTCCTTCAGCTGAAGTGGAAAAATGGACACAGTCATCATCGTCTGC
ATTTCTTGAAGAAAAGGTACATTTAAAAGAACTGTATGAGGTGCTTGGCTGTGTGCCAGTAGAT
GATCTGGAGGTGTATTTGAAACATCTTCTGCCAAAAATTGAGAATCTCTCTTATGATGCAAAAT
TGGAGCACTTGATCTATCTGAAGAATAGACTGGCAAGCATTGAGGAGCTGTCGGAGACTAAGGA
GCAACTTTTTGAGAAACTGGAAAGCTTATTGATTATTCATGATGCCAACAACCGACTAAAGCAA
GCGAAGCACTTCTATGATAGGACTGTGAGAGTTTTTGAAGTTATGCTTCCTGAAAAATTGTTTA
TTCCTAAAGAGTTCTTTAAAAAGTTGGAACAAGTAATAAAACCTAAAAATCAAGTTGTGTTTAT
GACATCCTGGGTGGAATTCTTGAGAAATATCGGGCTAAAGCATGTGCTTTCCCAGCAGCAGTTG
TTACAGTTTGCCAAGGAAATCAGTGTGCGGGCAAATACGGAAAACTGGTCTAAAGAAACGCTGC
AGAATACAGTTGACATCCTGCTCCATCACATATTCCAAGAACGAACGGATTTGCTATCTGGAAA
CTTTCTGAAAGAGCTGTCCTTAATACCCTTCTTGTGTCCGGAGCGGGCCCCTGCGGAATACATC
CGCTTTCACCCTCAGTACCAGGAGGTAAATGGAACACTTCCTCTTATCAAGTTCAATGGAGCAC
AGGTGAACCCAAAGTTCAAGCAGTGCGACGTTCTCCAGCTGCTGTGGACATCTTGCCCTATTCT
TCCGGAGAAAGCCACGCCGCTGAGCATCAAAGAACAAGAAGGCAGCAGCCTTGCCCCACAGGAA
CAGCTTGAACAAGTTTTAAATATGCTGAATGTTAACCTGGACCCCCCTCTTGATAAGGTCATTA
ATAACTGCAGAAACATATGCAACATAACAACTCTGGATGAGGAAATGGTAAAAACTAGAGCAAA
GGTCCTAAGGAGCATATATGAATTTCTCAGTGCAGAAAAACGGGAGTTCCGTTTTCAGCTTCGG
GGCGTGGCCTTTGTAATGGTAGAAGATGGCTGGAAACTTCTGAAGCCTGAGGAAGTGGTGATAA
ACCTGGAGTACGAAGCTGATTTTAAACCTTACTTGTACAAGCTGCCTTTGGAGCTCGGCACTTT
TCATCAGCTGTTCAAGCATTTAGGTACTGAAGATATCATCTCAACTAAGCAATACGTTGAAGTA
CTCAGCCGAATATTCAAAAACTCTGAAGGAAAGCAGCTAGACCCTAATGAAATGCGCACAGTTA
AAAGAGTGGTTTCTGGTCTGTTCAAGAGTCTACAAAACGATTCAGTTAAAGTGAGGAGCGATCT
GGAGAACGCCCGGGACCTCGCACTCTACCTTCCGAGCCAGGATGGTAGGTTGGTGAAGTCGAGC
ATCTTGGTGTTCGATGATGCACCACATTATAAAAGTAGAATCCAGGGTAATATTGGTGTGCAAA
TGCTAGTTGATCTTAGCCAGTGCTACTTAGGGAAAGACCACGGATTCCACACTAAGCTGATAAT
GCTCTTCCCTCAAAAGCTTCGACCTCGTCTGCTGAGCAGTATACTTGAAGAGCAGCTCGATGAG
GAGACCCCCAAAGTGTGCCAGTTTGGAGCATTGTGCTCTCTTCAGGGAAGACTGCAGCTTCTCC
TGTCTTCAGAGCAGTTCATCACAGGACTCATTAGAATCATGAAGCACGAGAATGACAATGCTTT
CCTGGCCAATGAAGAAAAGGCCATACGACTTTGCAAAGCTCTAAGAGAGGGGCTGAAAGTTTCC
TGTTTTGAAAAGCTTCAGACAACATTACGGGTTAAAGGTTTCAATCCTATTCCGCATAGCAGGA
GTGAAACTTTCGCTTTTCTAAAGCGATTTGGCAATGCCGTCATCTTGCTCTACATCCAGCATTC
AGACAGTAAAGACATTAACTTTCTGCTAGCCTTAGCGATGACACTTAAATCAGCAACTGACAAC
TTGATTTCTGACACATCATACTTAATTGCTATGCTGGGATGCAATGACATTTACAGGATCAGTG
AGAAACTTGACAGTTTAGGGGTTAAATATGACTCCTCAGAGCCATCCAAACTGGAGCTTCCCAT
GCCTGGCACACCAATACCTGCTGAGATCCACTATACACTACTTATGGATCCAATGAATGTTTTC
TATCCTGGGGAATATGTTGGGTACCTTGTGGATGCTGAAGGTGGTGATATCTACGGGTCATACC
AGCCAACATACACATATGCAATCATTGTGCAAGAAGTTGAAAGAGAAGATGCTGACAATGCTAG
TTTCTTGGGGAAGATCTATCAGATCGATATTGGCTACAGTGAATATAAGATAGTCAGCTCTCTG
GATCTGTACAAGTTCTCACGGCCTGATGAAAGCTCCCAGAGCAGAGACAGTGCTCCTACCACAC
CAACGAGCCCCACGGAATTCCTGACTCCCGGTCTGAGAAGCATCCCTCCTCTTTTCTCTGGCAA
AGAGAGCCACAAGCCTGCCTCCTCCAAACACCACTCCCCCAGAAAGCTCAAGGTGAATGCTTTA
CCAGAAATCCTGAAAGAAGTGACGTCAGTGGTGGAGCAAGCTTGGAAGCTTCCCGAGTCAGAAC
GGAAGAAGATCATTAGACGCTTGTATCTGAAGTGGCACCCTGACAAAAACCCAGAAAATCATGA
CATCGCTAATGAAGTGTTCAAGCATCTGCAGAATGAAATCAACAGACTAGAAAAACAGGCTTTT
CTGGATCAAAATGCAGACAGAGCTTCAAGAAGAACGTTTTCAACCTCTGCATCCCGATTTCAGT
CAGACAAGTACTCATTTCAAAGATTTTATACTTCGTGGAATCAAGAAGCCACAAGTCATAAATC
TGAAAGGCAACAGCAAAGTAAAGAGAAATGCCCTCCCTCTGCTGGACAGACATACTCTCAAAGG
TTCTTTGTTCCTCCCACCTTCAAGTCTGTGGGCAATCCAGTGGAAGCCCGGAGATGGTTAAGAC
AAGCCAGAGCAAACTTCTCAGCTGCCAGGAATGACCTTCACAAAAATGCCAATGAGTGGGTGTG
CTTCAAGTGCTACCTTTCCACCAAGCTGGCTTTGATTGCAGCCGACTATGCCGTCAGGGGGAAA
TCTGATAAAGACGTAAAGCCCACGGCGCTGGCCCAAAAGATAGAGGAGTATAGTCAGCAGCTGG
AGGGGCTGACAAACGATGTGCACACACTGGAAGCTTACGGTGTAGACAGCTTGAAAACAAGGTA
CCCTGATCTGCTTCCTTTTCCCCAGATCCCCAATGACAGGTTCACGTCTGAGGTCGCCATGAGG
GTGATGGAATGTACTGCCTGCATCATCATAAAACTTGAAAATTTTATACAACAGAAGGTATGAA
AGTGAAGAAAGCAGAGCCAGCTCCTGGGCGTGGTATAGCACAATCATGAATTGCTACACTCCAT
TCAGCTTCGTCGCCAGTGTCCAGGAATCGGGAAGCACAACGCGGAGTGTTCTGGAAGCATTCTG
AAGCTGTATGACTCCTAATAGATGGTTACAGAGCTGGAAACCGACTTTGAAGACGGCGGTGAGC
TGCAGAGTCTCTAGGTGTGTGGAAACGATTGGGTAGCACATTATTGATCTGCACTTTATGTAAC
CAAAGCTTAGCAGTCTGTTAGATAAGAGTCTGCACATGTCTCGGAGAGGAGGGAGTTAATTCTG
TGTTTTTAAACATGTTTTTGAAGTAGTTAAAGAAACACTGGACAGACTGATTTGGACATAAGAT
AGGGACTTGGGTTTGGGGACTTATCACTTTGTAAATGGACACTTTCAGATGCATTGTTTTATCA
GCTGGATCTGATTATGAGTTTGTTGCAGTTTCACGTCTTTAGTTGGACATTTACAGTATTTAAT
CCTGACTATTACTTGACTGAGTATGAAGATAGTCCTGGGGTGCACTGGGTGCATTCTCCACCCT
TGTTTTGATTTTTTATACCTTGTGTTTCTGGGCTTCCTGACTCGTGAAGATAACCTATGGATAT
CTCAGAGTGCTGGTACATACTACCAGATATTGCTTCTAAAACTGCTTCCCAATGTGACATTTAG
CAGAAGACCGTTGGAGTTTGTGTACATATCTTTCACAGATGTCATAATTTGTATAGAGTGGCTG
AACAGGATGCAATCTTTTGTCTAAAGGTGCTGCAGTGAAAAAAAACCCAACTGTCTTTCAATAT
GGCACTTAGTGGGAATTTAAACATTTTTACTTTAAGTATATTAAAAATGCTCAAATTGTTGAGG
TGATATGCAGACGTTTACAAAGGGAATTATCAGCTTGTACTGTCCCCCACGAGTGATTGAGAAC
TGACATTTAATTTTCATAATGTTCAAAATACCTAGCAAACATATTTAACATATTCTTTTGCATA
AAGTCAAAGAAAGGAAATATAGTTTATGTAAGTGCACTGGCTGTAAATGATGCTAATATATTTT
ATGCAATTAAGGGCTTACATACAGAACATGTTAGATTTTTTTTATTTCATTTGTAAAAAAGGAA
TGTTAATTGCTTCTGGATGTGAATCATGAATATTTCTGCTGTTAATATTAAGTGCCATGATTTT
AATAAAAAATGTATATAGAAAATCA

hide sequence

RefSeq Acc Id:

XM_039093905 ⟹ XP_038949833

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,523,577 - 39,546,416 (+)	NCBI
mRatBN7.2	15	35,347,480 - 35,370,335 (+)	NCBI

RefSeq Acc Id:

XM_063274272 ⟹ XP_063130342

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,461,860 - 39,546,416 (+)	NCBI

RefSeq Acc Id:

XM_063274273 ⟹ XP_063130343

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,499,629 - 39,546,416 (+)	NCBI

RefSeq Acc Id:

XM_063274274 ⟹ XP_063130344

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,511,146 - 39,546,416 (+)	NCBI

RefSeq Acc Id:

XM_063274275 ⟹ XP_063130345

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,461,859 - 39,533,208 (+)	NCBI

RefSeq Acc Id:

XM_063274276 ⟹ XP_063130346

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,461,859 - 39,533,824 (+)	NCBI

RefSeq Acc Id:

XM_063274277 ⟹ XP_063130347

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,461,859 - 39,533,208 (+)	NCBI

RefSeq Acc Id:

XM_063274278 ⟹ XP_063130348

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	39,461,859 - 39,528,602 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001414650	(Get FASTA)	NCBI Sequence Viewer
	XP_006252229	(Get FASTA)	NCBI Sequence Viewer
	XP_038949833	(Get FASTA)	NCBI Sequence Viewer
	XP_063130342	(Get FASTA)	NCBI Sequence Viewer
	XP_063130343	(Get FASTA)	NCBI Sequence Viewer
	XP_063130344	(Get FASTA)	NCBI Sequence Viewer
	XP_063130345	(Get FASTA)	NCBI Sequence Viewer
	XP_063130346	(Get FASTA)	NCBI Sequence Viewer
	XP_063130347	(Get FASTA)	NCBI Sequence Viewer
	XP_063130348	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL85271	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000019551
	ENSRNOP00000019551.5
	ENSRNOP00000095452
	ENSRNOP00000095452.1
	ENSRNOP00000095721
	ENSRNOP00000095721.1
	ENSRNOP00000103011

RefSeq Acc Id:	XP_006252229 ⟸ XM_006252167
- Peptide Label:	isoform X1
- UniProtKB:	D4A1D3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGTEETRWVRVTVLRGCVGCRTVAVRATATGRDLKERIFAETGFPVAEQRLWRGDREIPDWIKI GDLTSKTCLFVNLQSKGLKGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEV KFLYDETQYGTETLWSKDMAQYQGSALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIG FNSVYHITDVPCIFSGDQIGMLDPHQTLFGPHESGQCWNLKDDIKEINELPDQFAPFIGVFGST KETFTNGSFPGTFFRFPLRLQPSQLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVR EADGTEKLVFRVTASENKTLKHERPNSIKILGTAISNYCKKIPSNSVTCVTYHINIALEDESTK DAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGLAMSLSGRDEENGATSDFSGKAFCFLPL PPGEESRTGLPVHISGFFGLTDNRRSIKWRELDQWRDPAALWNQFLIVNVVPKAYATLILDSIK RLETEKSSDFPLSVDAIYKLWPEASKVKAHWHPVLGPLFSELFQHAVIYSVGGEWVKLEQVHFS ELDESLESTQSVLNYLQRSGKQIARVPGNLAAAVQLSAASATSTASPVRKVTPVWVRQVLRKCA HLGSAEEKLHLLEFVLSDQAYSELLGLELLPLQSGAFVPFSSSVSDQDVVYITSEEFPRSLFPG LEARLILENLKPHLLAALKEAAQTRAQQLLWGYSGRPCTQLQLLNPERFARLIKEVMNTFWPGR ELVVQWYPLSEDKHHPSISWLKMVWKNLYIHFSEDLTLFDEMPLIPRTPLDADQTCVELIRLRV PSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSLQHPLVKKYIHSPLPSAILQIMEKIPLQ KLCNQIASLLPTHKDALRKFLASLTDTSEKEKRIIQELTIFKRINHSSDQGISSYTKLKGCKVL DHTAKLPTELRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIENAFYTQEEVTRLML WILENLSSLKNENPSVLDWLMPLKFIHMSQEHVVAASDLFDPDIEVLRDLFYNEEEACFPPAVF TSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVSSCQNQDVLLKKAKTLLLVLNKNHTLL QSSEGKMALKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDAAHAVLVGSSLPLVESAH VSLEKTLGIFTKPTISAVLKHFKIVVDWYTSKTFSDEDYYQFQHILLEIYGFMHDHLSEGKDSF KALKYPWVWTGKNFCPLAQAVIKPIHDLDLQPYLYNVPKTMAKFHQLFKACGSIEELTSDHISM VIQKVYLKSDQELSEEESKQNLHLMLNIMRWLYSNQIPASPNTPVPIYHSKNPSKLVMKPIHEC CYCDIKVDDLNDLLEDSVEPIILVHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTV RIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSFN NSEFSDSDFINITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISK HIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSYNGTLFRLSFRTQQEA KVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPTLAQDTIIIKKKA CPSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEFHHVFRRIADLQSPLF RGPDDDPATLFEMAKSGQSKKPSDELPQKTVDCTTWLICTCMDTGEALKFSLNESGRRLGLVPC GAVGVLLHETQEQKWTVKPHIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGRWNT TFMRHVIVKAYLQALSVLRDLAISGELIDYTYYAVWPDPDVVHDDFSVICQGFYEDIAHGKGKD LTRVFSDGSMWVSMKNVRFLDDSILQRKDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKVGFE EAGCKQILLENTFSEKQFFSEVFFPNIQEIEAELRDPLMNFVLNEKLDEFSGILRVTPCVPCSL EGHPLVLPSRLIHPEGRVAKLFDIKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLER AESVAEINKSDHAAACLRSSILLSLIDEKLKIRDPRAKDFAAKYQTIPFLPFLTKPAGFSLEWK GNSFKPETMFAATDLYTAEYQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVI NQLKQVAKSVDDGITLYQENITNACYKYLHEAILQNEMAKATIIEKLKPFCFILVENVYVESEK VSFHLNFEAAPYLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQ LCRRIISEGIWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKDSSVKYCHA DIPREVAVKLGAIPKRHKALERYASNICFTAPGTEFGQKEKLTSRIKSILNAYPSEKEMLKELL QNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEG NPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSPGRMFRDLDADFRTQF SDVLDLYLGNHFKLDNCTMFRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLN HMEKISICEIDKATGGLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTM DTEDSEGNLTTWLICNRSGFSSMDKVSKSVISAHRNQDITLFPRGGVAACITHNYKKPHRAFCF LPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYF PGSDPTLSVLQNTPIHVVKDTLKKFLSFFPVNRLDLQPDLYCLVKALYSCIHEDMKRLLPVVRA PNIDGSDLHSAVIITWINMSTSNKTKPFFDNLLQDELQHLKNADYNITTRKTVAENVYRLKHLL LEIGFNLVYNCDETANLYHCLVDAAIPVSYVTPADVRSFLMTFSSPDTNCHIGKLPCRLQQTNL KLFHSLKLLVDYCFKDAEESEFEVEGLPLLITLDSVLQIFDGKRPKFLTTYHELIPSRKDLFMN TLYLKYSSVLLNCKVAKVFDISSFADLLSSVLPREYKTKNCAKWKDNFASESWLKNAWHFISES VSVTDDQEEPKPAFDVIVDILKDWALLPGTKFTVSASQLVVPEGDVLIPLSLMHIAVFPNAQSD KVFHALMKAGCIQLALNKICSKDSALVPLLSCHTANIDSPASILKAVHYMVQTSTFRTEKLVEN DFEALLMYFNCNLSHLMSQDDLKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQ SSSSAFLEEKVHLKELYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEEL SETKEQLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEFFKKLEQVIKPKN QVVFMTSWVEFLRNIGLKHVLSQQQLLQFAKEISVRANTENWSKETLQNTVDILLHHIFQERTD LLSGNFLKELSLIPFLCPERAPAEYIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQCDVLQLLWT SCPILPEKATPLSIKEQEGSSLAPQEQLEQVLNMLNVNLDPPLDKVINNCRNICNITTLDEEMV KTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEADFKPYLYKLPL ELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFKSLQNDSVK VRSDLENARDLALYLPSQDGRLVKSSILVFDDAPHYKSRIQGNIGVQMLVDLSQCYLGKDHGFH TKLIMLFPQKLRPRLLSSILEEQLDEETPKVCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHE NDNAFLANEEKAIRLCKALREGLKVSCFEKLQTTLRVKGFNPIPHSRSETFAFLKRFGNAVILL YIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRISEKLDSLGVKYDSSEPSK LELPMPGTPIPAEIHYTLLMDPMNVFYPGEYVGYLVDAEGGDIYGSYQPTYTYAIIVQEVERED ADNASFLGKIYQIDIGYSEYKIVSSLDLYKFSRPDESSQSRDSAPTTPTSPTEFLTPGLRSIPP LFSGKESHKPASSKHHSPRKLKVNALPEILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKN PENHDIANEVFKHLQNEINRLEKQAFLDQNADRASRRTFSTSASRFQSDKYSFQRFYTSWNQEA TSHKSERQQQSKEKCPPSAGQTYSQRFFVPPTFKSVGNPVEARRWLRQARANFSAARNDLHKNA NEWVCFKCYLSTKLALIAADYAVRGKSDKDVKPTALAQKIEEYSQQLEGLTNDVHTLEAYGVDS LKTRYPDLLPFPQIPNDRFTSEVAMRVMECTACIIIKLENFIQQKV hide sequence

Ensembl Acc Id:

ENSRNOP00000019551 ⟸ ENSRNOT00000019551

RefSeq Acc Id:	XP_038949833 ⟸ XM_039093905
- Peptide Label:	isoform X5
- UniProtKB:	A6K6B1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000095452 ⟸ ENSRNOT00000098951

Ensembl Acc Id:

ENSRNOP00000095721 ⟸ ENSRNOT00000113056

RefSeq Acc Id:	XP_063130346 ⟸ XM_063274276
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_063130345 ⟸ XM_063274275
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063130347 ⟸ XM_063274277
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_063130348 ⟸ XM_063274278
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_063130342 ⟸ XM_063274272
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6ATI0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063130343 ⟸ XM_063274273
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6B374 (UniProtKB/TrEMBL)

RefSeq Acc Id:

NP_001414650 ⟸ NM_001427721

RefSeq Acc Id:	XP_063130344 ⟸ XM_063274274
- Peptide Label:	isoform X4

Ensembl Acc Id:

ENSRNOP00000103011 ⟸ ENSRNOT00000168656

Protein Domains

HEPN J

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699739

Promoter ID:

EPDNEW_R10262

Type:

multiple initiation site

Name:

Sacs_1

Description:

sacsin molecular chaperone

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	41,448,084 - 41,448,144	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1307281	AgrOrtholog
BioCyc Gene	G2FUF-13513	BioCyc
Ensembl Genes	ENSRNOG00000014509	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000019551	ENTREZGENE
	ENSRNOT00000019551.7	UniProtKB/TrEMBL
	ENSRNOT00000098951	ENTREZGENE
	ENSRNOT00000098951.1	UniProtKB/TrEMBL
	ENSRNOT00000113056	ENTREZGENE
	ENSRNOT00000113056.1	UniProtKB/TrEMBL
	ENSRNOT00000168656	ENTREZGENE
Gene3D-CATH	1.10.287.110	UniProtKB/TrEMBL
	Nucleotidyltransferases domain 2	UniProtKB/TrEMBL
InterPro	DnaJ_dom_sf	UniProtKB/TrEMBL
	DnaJ_domain	UniProtKB/TrEMBL
	HATPase_C_sf	UniProtKB/TrEMBL
	HEPN	UniProtKB/TrEMBL
	Sacsin_chaperone_reg	UniProtKB/TrEMBL
	Ubiquitin-rel_dom	UniProtKB/TrEMBL
KEGG Report	rno:305940	UniProtKB/TrEMBL
NCBI Gene	305940	ENTREZGENE
PANTHER	SACSIN	UniProtKB/TrEMBL
	SACSIN	UniProtKB/TrEMBL
Pfam	HEPN	UniProtKB/TrEMBL
PharmGKB	SACS	RGD
PhenoGen	Sacs	PhenoGen
PROSITE	DNAJ_2	UniProtKB/TrEMBL
	HEPN	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014509	RatGTEx
SMART	HEPN	UniProtKB/TrEMBL
Superfamily-SCOP	ATP_bd_ATPase	UniProtKB/TrEMBL
	DnaJ_N	UniProtKB/TrEMBL
	Nucleotidyltransferase substrate binding subunit/domain	UniProtKB/TrEMBL
	SSF54236	UniProtKB/TrEMBL
UniProt	A0A8I6ATI0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B374	ENTREZGENE, UniProtKB/TrEMBL
	A6K6B1	ENTREZGENE, UniProtKB/TrEMBL
	D4A1D3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-02-06	Sacs	sacsin molecular chaperone	Sacs	spastic ataxia of Charlevoix-Saguenay (sacsin)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-06-15	Sacs	spastic ataxia of Charlevoix-Saguenay (sacsin)	RGD1305416	similar to RIKEN cDNA E130115J16	Data merged from RGD:1305416	1643240	APPROVED
2008-11-20	Sacs	spastic ataxia of Charlevoix-Saguenay (sacsin)	Sacs	sacsin	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Sacs	sacsin	Sacs_predicted	sacsin (predicted)	'predicted' is removed	2292626	APPROVED
2008-04-30	RGD1305416	similar to RIKEN cDNA E130115J16	RGD1305416_predicted	similar to RIKEN cDNA E130115J16 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-20	RGD1305416_predicted	similar to RIKEN cDNA E130115J16 (predicted)	LOC290301_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	Sacs_predicted	sacsin (predicted)			Symbol and Name status set to approved	70820	APPROVED
2005-01-12	LOC290301_predicted	similar to RIKEN cDNA E130115J16 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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