Dusp22 (dual specificity phosphatase 22) - Rat Genome Database

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Gene: Dusp22 (dual specificity phosphatase 22) Rattus norvegicus
Analyze
Symbol: Dusp22
Name: dual specificity phosphatase 22
RGD ID: 1307146
Description: Predicted to enable non-membrane spanning protein tyrosine phosphatase activity; protein tyrosine kinase binding activity; and protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of focal adhesion assembly; and negative regulation of non-membrane spanning protein tyrosine kinase activity. Predicted to act upstream of or within several processes, including negative regulation of T cell mediated immunity; negative regulation of T cell receptor signaling pathway; and negative regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and leading edge of lamellipodium. Predicted to be part of filamentous actin. Predicted to be active in cytosol and plasma membrane. Orthologous to human DUSP22 (dual specificity phosphatase 22); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: dual specificity protein phosphatase 22; LOC361242
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81733,989,637 - 34,040,021 (-)NCBIGRCr8
mRatBN7.21733,780,980 - 33,831,241 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1733,780,981 - 33,831,321 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1733,621,260 - 33,670,371 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01735,225,129 - 35,274,240 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01733,617,064 - 33,666,176 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01734,986,589 - 35,037,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1734,986,591 - 35,037,076 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01738,366,974 - 38,417,681 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41740,229,790 - 40,281,414 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11740,232,640 - 40,394,580 (-)NCBI
Celera1733,321,675 - 33,372,005 (-)NCBICelera
Cytogenetic Map17p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
amenorrhea  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12138158   PMID:16636663   PMID:20018849   PMID:24714587  


Genomics

Comparative Map Data
Dusp22
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81733,989,637 - 34,040,021 (-)NCBIGRCr8
mRatBN7.21733,780,980 - 33,831,241 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1733,780,981 - 33,831,321 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1733,621,260 - 33,670,371 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01735,225,129 - 35,274,240 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01733,617,064 - 33,666,176 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01734,986,589 - 35,037,297 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1734,986,591 - 35,037,076 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01738,366,974 - 38,417,681 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41740,229,790 - 40,281,414 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11740,232,640 - 40,394,580 (-)NCBI
Celera1733,321,675 - 33,372,005 (-)NCBICelera
Cytogenetic Map17p12NCBI
DUSP22
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386292,487 - 351,355 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6291,630 - 351,355 (+)EnsemblGRCh38hg38GRCh38
GRCh376292,487 - 351,355 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366237,101 - 296,355 (+)NCBINCBI36Build 36hg18NCBI36
Build 346237,100 - 296,353NCBI
Celera63,913 - 4,374 (-)NCBICelera
Cytogenetic Map6p25.3NCBI
HuRef6218,216 - 221,471 (+)NCBIHuRef
HuRef6144,304 - 164,165 (+)NCBIHuRef
CHM1_16290,513 - 349,836 (+)NCBICHM1_1
T2T-CHM13v2.06147,423 - 206,310 (+)NCBIT2T-CHM13v2.0
Dusp22
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391330,844,042 - 30,895,215 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1330,843,982 - 30,895,214 (+)EnsemblGRCm39 Ensembl
GRCm381330,660,059 - 30,711,232 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1330,659,999 - 30,711,231 (+)EnsemblGRCm38mm10GRCm38
MGSCv371330,751,965 - 30,803,094 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361330,667,561 - 30,718,690 (+)NCBIMGSCv36mm8
Celera1330,874,241 - 30,925,414 (+)NCBICelera
Cytogenetic Map13A3.2NCBI
cM Map1313.26NCBI
Dusp22
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546512,551,063 - 12,592,572 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546512,551,063 - 12,597,386 (-)NCBIChiLan1.0ChiLan1.0
DUSP22
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2514,906,929 - 14,983,734 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1610,898,167 - 10,974,897 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06107,145 - 180,777 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16242,121 - 301,248 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6242,121 - 301,248 (+)Ensemblpanpan1.1panPan2
DUSP22
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.135678,320 - 733,225 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl35678,155 - 732,397 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha35689,526 - 745,448 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.035625,303 - 681,338 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl35625,022 - 680,993 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.135611,650 - 667,585 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.035630,246 - 686,012 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0351,965,530 - 2,021,399 (+)NCBIUU_Cfam_GSD_1.0
Dusp22
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494625,092,590 - 25,161,088 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366331,459,386 - 1,528,082 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366331,459,487 - 1,528,080 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DUSP22
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl743,487 - 96,267 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1743,437 - 96,270 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DUSP22
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11771,798,515 - 71,855,642 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1771,799,014 - 71,855,601 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666044217,631 - 275,611 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dusp22
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475623,968,017 - 24,017,332 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475623,968,148 - 24,017,340 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dusp22
188 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:45
Count of miRNA genes:44
Interacting mature miRNAs:45
Transcripts:ENSRNOT00000024587
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)172738994653481766Rat
70157Niddm32Non-insulin dependent diabetes mellitus QTL 324.34blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)172245492450909196Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
2313854Bp343Blood pressure QTL 3433.9life span trait (VT:0005372)age at time of death (CMO:0001193)173199078450909196Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
4889891Eae32Experimental allergic encephalomyelitis QTL 324.80.0002nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)172702794936146731Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat

Markers in Region
RH131606  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2127,212,139 - 7,212,330 (-)MAPPERmRatBN7.2
mRatBN7.21733,781,020 - 33,781,210 (+)MAPPERmRatBN7.2
Rnor_6.0128,939,369 - 8,939,559NCBIRnor6.0
Rnor_6.01734,986,630 - 34,986,819NCBIRnor6.0
Rnor_5.01738,417,451 - 38,417,640UniSTSRnor5.0
Rnor_5.01211,057,446 - 11,057,636UniSTSRnor5.0
RGSC_v3.41740,229,829 - 40,230,018UniSTSRGSC3.4
Celera1733,321,714 - 33,321,903UniSTS
Cytogenetic Map17p12UniSTS
RH143737  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01211,057,403 - 11,057,540NCBIRnor5.0
Rnor_5.01210,913,859 - 10,913,996NCBIRnor5.0
Rnor_5.01738,417,408 - 38,417,544NCBIRnor5.0
RGSC_v3.41740,229,925 - 40,230,060UniSTSRGSC3.4
RGSC_v3.4127,770,706 - 7,770,842UniSTSRGSC3.4
Celera1733,321,810 - 33,321,945UniSTS
Celera128,955,241 - 8,955,377UniSTS
Cytogenetic Map17p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000090946   ⟹   ENSRNOP00000071916
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1733,780,982 - 33,825,502 (-)Ensembl
Rnor_6.0 Ensembl1734,986,591 - 35,037,076 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094585   ⟹   ENSRNOP00000092639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1733,780,981 - 33,831,321 (-)Ensembl
RefSeq Acc Id: NM_001108412   ⟹   NP_001101882
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,637 - 34,039,895 (-)NCBI
mRatBN7.21733,780,980 - 33,831,241 (-)NCBI
Rnor_6.01734,986,591 - 35,037,076 (-)NCBI
Rnor_5.01738,366,974 - 38,417,681 (+)NCBI
RGSC_v3.41740,229,790 - 40,281,414 (-)RGD
Celera1733,321,675 - 33,372,005 (-)RGD
Sequence:
RefSeq Acc Id: NM_001399248   ⟹   NP_001386177
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,637 - 34,039,895 (-)NCBI
mRatBN7.21733,780,980 - 33,831,241 (-)NCBI
RefSeq Acc Id: XM_006253888   ⟹   XP_006253950
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,649 - 34,039,835 (-)NCBI
mRatBN7.21733,780,980 - 33,831,169 (-)NCBI
Rnor_6.01734,986,595 - 35,036,928 (-)NCBI
Rnor_5.01738,366,974 - 38,417,681 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600602   ⟹   XP_017456091
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,649 - 34,034,317 (-)NCBI
mRatBN7.21733,780,980 - 33,825,746 (-)NCBI
Rnor_6.01734,986,595 - 35,036,832 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017600603   ⟹   XP_017456092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,649 - 34,034,148 (-)NCBI
mRatBN7.21733,780,980 - 33,825,731 (-)NCBI
Rnor_6.01734,986,589 - 35,036,832 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039095884   ⟹   XP_038951812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,649 - 34,034,377 (-)NCBI
mRatBN7.21733,780,980 - 33,829,398 (-)NCBI
RefSeq Acc Id: XM_063276589   ⟹   XP_063132659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,649 - 34,039,816 (-)NCBI
RefSeq Acc Id: XM_063276590   ⟹   XP_063132660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,649 - 34,040,021 (-)NCBI
RefSeq Acc Id: XM_063276591   ⟹   XP_063132661
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,649 - 34,040,013 (-)NCBI
RefSeq Acc Id: XM_063276592   ⟹   XP_063132662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81733,989,649 - 34,031,952 (-)NCBI
RefSeq Acc Id: NP_001101882   ⟸   NM_001108412
- Peptide Label: isoform 1
- UniProtKB: A6J7L5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253950   ⟸   XM_006253888
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017456092   ⟸   XM_017600603
- Peptide Label: isoform X3
- UniProtKB: D3ZC16 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456091   ⟸   XM_017600602
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000071916   ⟸   ENSRNOT00000090946
RefSeq Acc Id: XP_038951812   ⟸   XM_039095884
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000092639   ⟸   ENSRNOT00000094585
RefSeq Acc Id: NP_001386177   ⟸   NM_001399248
- Peptide Label: isoform 2
- UniProtKB: A0A8I6AGY7 (UniProtKB/TrEMBL),   A6J7L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063132660   ⟸   XM_063276590
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063132661   ⟸   XM_063276591
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063132659   ⟸   XM_063276589
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063132662   ⟸   XM_063276592
- Peptide Label: isoform X7
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZC16-F1-model_v2 AlphaFold D3ZC16 1-184 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700426
Promoter ID:EPDNEW_R10949
Type:initiation region
Name:Dusp22_1
Description:dual specificity phosphatase 22
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01735,037,003 - 35,037,063EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307146 AgrOrtholog
BioCyc Gene G2FUF-9536 BioCyc
Ensembl Genes ENSRNOG00000056376 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000090946.2 UniProtKB/TrEMBL
  ENSRNOT00000094585.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/TrEMBL
InterPro Dual-sp/Tyr_phosphatase UniProtKB/TrEMBL
  Dual-sp_phosphatase_cat-dom UniProtKB/TrEMBL
  Dual-sp_phosphatase_subgr_cat UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
KEGG Report rno:361242 UniProtKB/TrEMBL
NCBI Gene 361242 ENTREZGENE
PANTHER DUAL SPECIFICITY PROTEIN PHOSPHATASE 22 UniProtKB/TrEMBL
  DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED UniProtKB/TrEMBL
Pfam DSPc UniProtKB/TrEMBL
PhenoGen Dusp22 PhenoGen
PRINTS ADSPHPHTASE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056376 RatGTEx
SMART DSPc UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
UniProt A0A8I6AGY7 ENTREZGENE, UniProtKB/TrEMBL
  A6J7L5 ENTREZGENE, UniProtKB/TrEMBL
  A6J7L7 ENTREZGENE, UniProtKB/TrEMBL
  D3ZC16 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Dusp22  dual specificity phosphatase 22   Dusp22_predicted  dual specificity phosphatase 22 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dusp22_predicted  dual specificity phosphatase 22 (predicted)      Symbol and Name status set to approved 70820 APPROVED