Gpx7 (glutathione peroxidase 7) - Rat Genome Database

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Gene: Gpx7 (glutathione peroxidase 7) Rattus norvegicus
Analyze
Symbol: Gpx7
Name: glutathione peroxidase 7
RGD ID: 1306999
Description: Predicted to enable catalase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Barrett's adenocarcinoma and Barrett's esophagus. Orthologous to human GPX7 (glutathione peroxidase 7); PARTICIPATES IN arachidonic acid metabolic pathway; glutathione metabolic pathway; INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC298376
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85128,373,881 - 128,381,866 (-)NCBIGRCr8
mRatBN7.25123,145,151 - 123,153,141 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5123,144,331 - 123,153,004 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5125,767,857 - 125,775,729 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05127,490,918 - 127,498,790 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05127,542,230 - 127,550,102 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05128,001,766 - 128,009,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5128,001,761 - 128,009,735 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05131,847,356 - 131,855,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45129,506,986 - 129,514,830 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15129,512,627 - 129,520,020 (-)NCBI
Celera5121,881,045 - 121,888,871 (-)NCBICelera
Cytogenetic Map5q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-naringenin  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
Azoxymethane  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cerium trichloride  (ISO)
chlorpyrifos  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dimethylarsinic acid  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
furan  (EXP)
inulin  (ISO)
ivermectin  (ISO)
lanthanum trichloride  (ISO)
lycopene  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
naphthalene  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP)
phlorizin  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
Pyridostigmine bromide  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
troglitazone  (ISO)
Tungsten carbide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma. Peng DF, etal., Gut. 2009 Jan;58(1):5-15. doi: 10.1136/gut.2007.146290. Epub 2008 Jul 29.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21215271   PMID:22157330   PMID:28751022   PMID:37761814  


Genomics

Comparative Map Data
Gpx7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85128,373,881 - 128,381,866 (-)NCBIGRCr8
mRatBN7.25123,145,151 - 123,153,141 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5123,144,331 - 123,153,004 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5125,767,857 - 125,775,729 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05127,490,918 - 127,498,790 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05127,542,230 - 127,550,102 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05128,001,766 - 128,009,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5128,001,761 - 128,009,735 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05131,847,356 - 131,855,200 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45129,506,986 - 129,514,830 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15129,512,627 - 129,520,020 (-)NCBI
Celera5121,881,045 - 121,888,871 (-)NCBICelera
Cytogenetic Map5q34NCBI
GPX7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38152,602,371 - 52,609,051 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl152,602,371 - 52,609,051 (+)EnsemblGRCh38hg38GRCh38
GRCh37153,068,043 - 53,074,723 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36152,840,632 - 52,847,310 (+)NCBINCBI36Build 36hg18NCBI36
Celera151,354,739 - 51,361,416 (+)NCBICelera
Cytogenetic Map1p32.3NCBI
HuRef151,188,252 - 51,190,619 (+)NCBIHuRef
CHM1_1153,185,389 - 53,192,069 (+)NCBICHM1_1
T2T-CHM13v2.0152,483,604 - 52,490,521 (+)NCBIT2T-CHM13v2.0
Gpx7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394108,257,414 - 108,263,910 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4108,257,587 - 108,264,158 (-)EnsemblGRCm39 Ensembl
GRCm384108,400,217 - 108,406,713 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4108,400,390 - 108,406,961 (-)EnsemblGRCm38mm10GRCm38
MGSCv374108,072,822 - 108,079,318 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364107,898,343 - 107,904,646 (-)NCBIMGSCv36mm8
Celera4106,743,612 - 106,750,115 (-)NCBICelera
Cytogenetic Map4C7NCBI
cM Map450.5NCBI
Gpx7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554646,558,336 - 6,566,763 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554646,560,198 - 6,566,763 (-)NCBIChiLan1.0ChiLan1.0
GPX7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21174,239,774 - 174,246,782 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11173,382,173 - 173,388,926 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0151,827,000 - 51,870,924 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1153,471,583 - 53,478,074 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl153,471,624 - 53,477,448 (+)Ensemblpanpan1.1panPan2
GPX7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1158,777,626 - 8,784,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha158,930,091 - 8,937,758 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0158,900,791 - 8,908,468 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl158,901,496 - 8,908,454 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1158,713,988 - 8,721,699 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0158,803,072 - 8,810,744 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0158,819,680 - 8,827,419 (-)NCBIUU_Cfam_GSD_1.0
Gpx7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505867,027,132 - 67,034,547 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365228,381,377 - 8,389,357 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365228,381,678 - 8,388,800 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPX7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6159,590,482 - 159,599,293 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16159,590,479 - 159,598,768 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GPX7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12080,335,248 - 80,342,687 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2080,335,033 - 80,342,124 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603336,929,160 - 36,936,411 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpx7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624859618,517 - 624,610 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624859618,517 - 624,635 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gpx7
40 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:106
Interacting mature miRNAs:109
Transcripts:ENSRNOT00000013913
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1582230Bw78Body weight QTL 783.20.0016epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)5119085612128034027Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
7794739Bp372Blood pressure QTL 3720.0058arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5117913688125222967Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5120740824143608494Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000013913   ⟹   ENSRNOP00000013913
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5123,144,466 - 123,152,979 (-)Ensembl
Rnor_6.0 Ensembl5128,001,761 - 128,009,735 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108739   ⟹   ENSRNOP00000097358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5123,144,331 - 123,153,004 (-)Ensembl
RefSeq Acc Id: NM_001106673   ⟹   NP_001100143
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,373,881 - 128,381,725 (-)NCBI
mRatBN7.25123,145,158 - 123,153,004 (-)NCBI
Rnor_6.05128,001,766 - 128,009,610 (-)NCBI
Rnor_5.05131,847,356 - 131,855,200 (-)NCBI
RGSC_v3.45129,506,986 - 129,514,830 (-)RGD
Celera5121,881,045 - 121,888,871 (-)RGD
Sequence:
RefSeq Acc Id: XM_039109576   ⟹   XP_038965504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85128,373,886 - 128,381,866 (-)NCBI
mRatBN7.25123,145,151 - 123,153,141 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001100143 (Get FASTA)   NCBI Sequence Viewer  
  XP_038965504 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL90404 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013913.5
  ENSRNOP00000097358.1
RefSeq Acc Id: NP_001100143   ⟸   NM_001106673
- Peptide Label: precursor
- UniProtKB: D3ZQI1 (UniProtKB/TrEMBL),   A6JYU9 (UniProtKB/TrEMBL),   A0A8I6ARN0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013913   ⟸   ENSRNOT00000013913
RefSeq Acc Id: XP_038965504   ⟸   XM_039109576
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000097358   ⟸   ENSRNOT00000108739

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQI1-F1-model_v2 AlphaFold D3ZQI1 1-186 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693901
Promoter ID:EPDNEW_R4425
Type:initiation region
Name:Gpx7_1
Description:glutathione peroxidase 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05128,009,563 - 128,009,623EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306999 AgrOrtholog
BioCyc Gene G2FUF-40388 BioCyc
Ensembl Genes ENSRNOG00000009751 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013913.7 UniProtKB/TrEMBL
  ENSRNOT00000108739.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro Glut_perox_Gpx7 UniProtKB/TrEMBL
  Glutathione_peroxidase UniProtKB/TrEMBL
  GPX_AS UniProtKB/TrEMBL
  GPX_CS UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
KEGG Report rno:298376 UniProtKB/TrEMBL
NCBI Gene 298376 ENTREZGENE
PANTHER Glut_peroxidase UniProtKB/TrEMBL
  GLUTATHIONE PEROXIDASE 7 UniProtKB/TrEMBL
Pfam GSHPx UniProtKB/TrEMBL
PhenoGen Gpx7 PhenoGen
PIRSF Glutathion_perox UniProtKB/TrEMBL
PRINTS GLUTPROXDASE UniProtKB/TrEMBL
PROSITE GLUTATHIONE_PEROXID_1 UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_2 UniProtKB/TrEMBL
  GLUTATHIONE_PEROXID_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009751 RatGTEx
Superfamily-SCOP Thiordxn-like_fd UniProtKB/TrEMBL
UniProt A0A8I6ARN0 ENTREZGENE, UniProtKB/TrEMBL
  A6JYU9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQI1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Gpx7  glutathione peroxidase 7   Gpx7_predicted  glutathione peroxidase 7 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Gpx7_predicted  glutathione peroxidase 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED