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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of JADE1 mRNA] | CTD | PMID:31150632 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1315810 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of JADE1 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1315810 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of JADE1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:1315810 | 6480464 | Ethinyl Estradiol affects the expression of JADE1 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of JADE1 mRNA | CTD | PMID:29097150 | 17beta-estradiol | decreases expression | ISO | RGD:1315810 | 6480464 | Estradiol results in decreased expression of JADE1 mRNA | CTD | PMID:22467019 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1315810 | 6480464 | Tetrachlorodibenzodioxin affects the expression of JADE1 mRNA | CTD | PMID:21570461, PMID:24680724 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of JADE1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of JADE1 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of JADE1 mRNA | CTD | PMID:22298810, PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1315810 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of JADE1 mRNA | CTD | PMID:19770486, PMID:19933214 | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of JADE1 mRNA | CTD | PMID:21061450 | 2-methylcholine | affects expression | ISO | RGD:1315809 | 6480464 | beta-methylcholine affects the expression of JADE1 mRNA | CTD | PMID:21179406 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | RGD:1315810 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of JADE1 mRNA | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | increases methylation | ISO | RGD:1315810 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased methylation of JADE1 promoter | CTD | PMID:26251327 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1315809 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of JADE1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of JADE1 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | RGD:1315810 | 6480464 | 4, 4'-diaminodiphenylmethane results in decreased expression of JADE1 mRNA | CTD | PMID:18648102 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of JADE1 mRNA | CTD | PMID:24780913 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of JADE1 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases expression | ISO | RGD:1315809 | 6480464 | Aflatoxin B1 results in decreased expression of JADE1 mRNA | CTD | PMID:21641981 | all-trans-retinoic acid | decreases expression | ISO | RGD:1315809 | 6480464 | Tretinoin results in decreased expression of JADE1 mRNA | CTD | PMID:21934132, PMID:33167477 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of JADE1 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | RGD:1315809 | 6480464 | aristolochic acid I results in decreased expression of JADE1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | RGD:1315809 | 6480464 | Arsenic affects the methylation of JADE1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1315809 | 6480464 | Arsenic affects the methylation of JADE1 gene | CTD | PMID:25304211 | arsenite(3-) | multiple interactions | ISO | RGD:1315809 | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to JADE1 mRNA] | CTD | PMID:32406909 | atrazine | increases expression | ISO | RGD:1315809 | 6480464 | Atrazine results in increased expression of JADE1 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | multiple interactions | ISO | RGD:1315810 | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of JADE1 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | decreases methylation | ISO | RGD:1315810 | 6480464 | Benzo(a)pyrene results in decreased methylation of JADE1 exon, Benzo(a)pyrene results in decreased methylation of JADE1 intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | RGD:1315809 | 6480464 | Benzo(a)pyrene results in decreased expression of JADE1 mRNA | CTD | PMID:20064835, PMID:26238291 | benzo[a]pyrene | increases expression | ISO | RGD:1315810 | 6480464 | Benzo(a)pyrene results in increased expression of JADE1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1315809 | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of JADE1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:1315810 | 6480464 | bisphenol A results in decreased expression of JADE1 mRNA | CTD | PMID:33221593 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of JADE1 mRNA | CTD | PMID:33296240 | bisphenol A | multiple interactions | ISO | RGD:1315809 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of JADE1 mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | ISO | RGD:1315809 | 6480464 | bisphenol A results in decreased expression of JADE1 mRNA | CTD | PMID:27685785 | bisphenol F | multiple interactions | ISO | RGD:1315809 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of JADE1 mRNA | CTD | PMID:28628672 | butanal | decreases expression | ISO | RGD:1315809 | 6480464 | butyraldehyde results in decreased expression of JADE1 mRNA | CTD | PMID:26079696 | cadmium atom | decreases expression | ISO | RGD:1315810 | 6480464 | Cadmium results in decreased expression of JADE1 mRNA | CTD | PMID:24067728 | cadmium atom | multiple interactions | ISO | RGD:1315809 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of JADE1 mRNA | CTD | PMID:35301059 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of JADE1 mRNA | CTD | PMID:33453195 | cadmium dichloride | multiple interactions | ISO | RGD:1315809 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of JADE1 mRNA | CTD | PMID:35301059 | carbon nanotube | decreases expression | ISO | RGD:1315810 | 6480464 | Nanotubes more ... | CTD | PMID:25554681, PMID:25620056 | CGP 52608 | multiple interactions | ISO | RGD:1315809 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to JADE1 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | RGD:1315810 | 6480464 | Chlorpyrifos results in increased expression of JADE1 mRNA | CTD | PMID:32715474 | cisplatin | multiple interactions | ISO | RGD:1315809 | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of JADE1 mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | RGD:1315809 | 6480464 | Cisplatin results in decreased expression of JADE1 mRNA | CTD | PMID:27392435 | cobalt dichloride | increases expression | ISO | RGD:1315810 | 6480464 | cobaltous chloride results in increased expression of JADE1 mRNA | CTD | PMID:21139344 | copper(II) sulfate | decreases expression | ISO | RGD:1315809 | 6480464 | Copper Sulfate results in decreased expression of JADE1 mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | ISO | RGD:1315810 | 6480464 | Asbestos, Crocidolite results in decreased expression of JADE1 mRNA | CTD | PMID:29279043 | cyclosporin A | decreases expression | ISO | RGD:1315810 | 6480464 | Cyclosporine results in decreased expression of JADE1 mRNA | CTD | PMID:19770486 | cyclosporin A | decreases expression | ISO | RGD:1315809 | 6480464 | Cyclosporine results in decreased expression of JADE1 mRNA | CTD | PMID:27989131 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of JADE1 mRNA | CTD | PMID:23640034 | dexamethasone | decreases expression | EXP | | 6480464 | Dexamethasone results in decreased expression of JADE1 mRNA | CTD | PMID:20032058 | dexamethasone | multiple interactions | ISO | RGD:1315809 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of JADE1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of JADE1 mRNA | CTD | PMID:28628672 | dexamethasone | increases expression | ISO | RGD:1315809 | 6480464 | Dexamethasone results in increased expression of JADE1 mRNA | CTD | PMID:25047013 | dexamethasone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of JADE1 mRNA] | CTD | PMID:20032058 | dorsomorphin | multiple interactions | ISO | RGD:1315809 | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | epoxiconazole | decreases expression | ISO | RGD:1315810 | 6480464 | epoxiconazole results in decreased expression of JADE1 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | ISO | RGD:1315810 | 6480464 | Ethanol affects the splicing of JADE1 mRNA | CTD | PMID:30319688 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of JADE1 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:1315810 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of JADE1 mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | ISO | RGD:1315809 | 6480464 | Formaldehyde results in decreased expression of JADE1 mRNA | CTD | PMID:20655997 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of JADE1 mRNA | CTD | PMID:33387578 | hydrogen peroxide | affects expression | ISO | RGD:1315809 | 6480464 | Hydrogen Peroxide affects the expression of JADE1 mRNA | CTD | PMID:20044591 | indometacin | multiple interactions | ISO | RGD:1315809 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of JADE1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of JADE1 mRNA | CTD | PMID:28628672 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of JADE1 mRNA | CTD | PMID:30467583 | methylmercury chloride | decreases expression | ISO | RGD:1315809 | 6480464 | methylmercuric chloride results in decreased expression of JADE1 mRNA | CTD | PMID:28001369 | microcystin-LR | decreases expression | ISO | RGD:1315809 | 6480464 | cyanoginosin LR results in decreased expression of JADE1 mRNA | CTD | PMID:27796937 | N-methyl-4-phenylpyridinium | decreases expression | ISO | RGD:1315809 | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of JADE1 mRNA | CTD | PMID:24810058 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of JADE1 mRNA | CTD | PMID:24136188 | nickel atom | decreases expression | ISO | RGD:1315809 | 6480464 | Nickel results in decreased expression of JADE1 mRNA | CTD | PMID:25583101 | ozone | multiple interactions | ISO | RGD:1315810 | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of JADE1 mRNA, [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of JADE1 mRNA | CTD | PMID:34911549 | p-chloromercuribenzoic acid | decreases expression | ISO | RGD:1315809 | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of JADE1 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | RGD:1315809 | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of JADE1 mRNA | CTD | PMID:27188386 | paracetamol | affects expression | ISO | RGD:1315810 | 6480464 | Acetaminophen affects the expression of JADE1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of JADE1 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | RGD:1315809 | 6480464 | Acetaminophen results in decreased expression of JADE1 mRNA | CTD | PMID:29067470 | parathion | increases expression | ISO | RGD:1315810 | 6480464 | Parathion results in increased expression of JADE1 mRNA | CTD | PMID:34813904 | phenobarbital | affects expression | ISO | RGD:1315810 | 6480464 | Phenobarbital affects the expression of JADE1 mRNA | CTD | PMID:23091169 | phenylmercury acetate | decreases expression | ISO | RGD:1315809 | 6480464 | Phenylmercuric Acetate results in decreased expression of JADE1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | RGD:1315809 | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of JADE1 mRNA | CTD | PMID:27188386 | pirinixic acid | decreases expression | ISO | RGD:1315810 | 6480464 | pirinixic acid results in decreased expression of JADE1 mRNA | CTD | PMID:23811191 | progesterone | increases expression | ISO | RGD:1315809 | 6480464 | Progesterone results in increased expression of JADE1 mRNA | CTD | PMID:20864642, PMID:21795739 | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of JADE1 mRNA | CTD | PMID:25905778 | resveratrol | multiple interactions | ISO | RGD:1315809 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of JADE1 mRNA | CTD | PMID:23557933 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of JADE1 mRNA | CTD | PMID:28374803 | SB 431542 | multiple interactions | ISO | RGD:1315809 | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | RGD:1315810 | 6480464 | Silicon Dioxide results in decreased expression of JADE1 mRNA | CTD | PMID:19073995 | silver atom | decreases expression | ISO | RGD:1315810 | 6480464 | Silver results in decreased expression of JADE1 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | RGD:1315810 | 6480464 | Silver results in decreased expression of JADE1 mRNA | CTD | PMID:27131904 | sodium arsenate | increases expression | ISO | RGD:1315810 | 6480464 | sodium arsenate results in increased expression of JADE1 mRNA | CTD | PMID:21795629 | succimer | multiple interactions | ISO | RGD:1315810 | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of JADE1 mRNA | CTD | PMID:21641980 | testosterone | multiple interactions | EXP | | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of JADE1 mRNA] | CTD | PMID:20032058 | testosterone | increases expression | ISO | RGD:1315810 | 6480464 | Testosterone deficiency results in increased expression of JADE1 mRNA | CTD | PMID:33848595 | tetrachloromethane | affects expression | ISO | RGD:1315810 | 6480464 | Carbon Tetrachloride affects the expression of JADE1 mRNA | CTD | PMID:17484886 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of JADE1 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of JADE1 mRNA] | CTD | PMID:31150632 | tetraphene | decreases expression | ISO | RGD:1315810 | 6480464 | benz(a)anthracene results in decreased expression of JADE1 mRNA | CTD | PMID:26377693 | theophylline | increases expression | ISO | RGD:1315809 | 6480464 | Theophylline results in increased expression of JADE1 mRNA | CTD | PMID:18951874 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of JADE1 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | RGD:1315810 | 6480464 | titanium dioxide results in decreased expression of JADE1 mRNA | CTD | PMID:23557971 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of JADE1 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | RGD:1315809 | 6480464 | trichostatin A results in decreased expression of JADE1 mRNA | CTD | PMID:24935251, PMID:26272509 | trichostatin A | multiple interactions | ISO | RGD:1315809 | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of JADE1 mRNA | CTD | PMID:27188386 | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of JADE1 mRNA | CTD | PMID:30589522 | triptonide | affects expression | ISO | RGD:1315810 | 6480464 | triptonide affects the expression of JADE1 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | ISO | RGD:1315810 | 6480464 | troglitazone results in decreased expression of JADE1 mRNA | CTD | PMID:28973697 | trovafloxacin | decreases expression | ISO | RGD:1315810 | 6480464 | trovafloxacin results in decreased expression of JADE1 mRNA | CTD | PMID:35537566 | valproic acid | increases methylation | ISO | RGD:1315809 | 6480464 | Valproic Acid results in increased methylation of JADE1 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | RGD:1315809 | 6480464 | Valproic Acid results in decreased expression of JADE1 mRNA | CTD | PMID:19101580 more ... | valproic acid | affects expression | ISO | RGD:1315809 | 6480464 | Valproic Acid affects the expression of JADE1 mRNA | CTD | PMID:25979313 | valproic acid | multiple interactions | ISO | RGD:1315809 | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of JADE1 mRNA | CTD | PMID:27188386 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of JADE1 mRNA | CTD | PMID:29427782 | |