Mrps35 (mitochondrial ribosomal protein S35) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Mrps35 (mitochondrial ribosomal protein S35) Rattus norvegicus
Analyze
Symbol: Mrps35
Name: mitochondrial ribosomal protein S35
RGD ID: 1306720
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Orthologous to human MRPS35 (mitochondrial ribosomal protein S35); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 28S ribosomal protein S35, mitochondrial; LOC297727; small ribosomal subunit protein mS35
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84181,688,715 - 181,719,403 (+)NCBIGRCr8
mRatBN7.24179,958,067 - 179,988,752 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4179,958,083 - 179,987,710 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4186,242,484 - 186,273,380 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04182,026,991 - 182,057,885 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04180,647,436 - 180,678,335 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04181,434,793 - 181,465,318 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4181,434,812 - 181,465,318 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04245,584,679 - 245,615,196 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44184,642,428 - 184,673,097 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14184,887,582 - 184,917,056 (+)NCBI
Celera4168,451,594 - 168,482,258 (+)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18614015   PMID:22681889   PMID:25931508   PMID:34800366  


Genomics

Comparative Map Data
Mrps35
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84181,688,715 - 181,719,403 (+)NCBIGRCr8
mRatBN7.24179,958,067 - 179,988,752 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4179,958,083 - 179,987,710 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4186,242,484 - 186,273,380 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04182,026,991 - 182,057,885 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04180,647,436 - 180,678,335 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04181,434,793 - 181,465,318 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4181,434,812 - 181,465,318 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04245,584,679 - 245,615,196 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44184,642,428 - 184,673,097 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14184,887,582 - 184,917,056 (+)NCBI
Celera4168,451,594 - 168,482,258 (+)NCBICelera
Cytogenetic Map4q44NCBI
MRPS35
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381227,710,832 - 27,756,295 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1227,710,822 - 27,756,295 (+)EnsemblGRCh38hg38GRCh38
GRCh371227,863,765 - 27,909,228 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361227,754,996 - 27,800,495 (+)NCBINCBI36Build 36hg18NCBI36
Build 341227,754,995 - 27,800,494NCBI
Celera1233,009,297 - 33,054,807 (+)NCBICelera
Cytogenetic Map12p11.22NCBI
HuRef1227,632,567 - 27,678,311 (+)NCBIHuRef
CHM1_11227,828,692 - 27,874,201 (+)NCBICHM1_1
T2T-CHM13v2.01227,582,568 - 27,628,010 (+)NCBIT2T-CHM13v2.0
Mrps35
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396146,944,270 - 146,972,399 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6146,944,262 - 146,975,489 (+)EnsemblGRCm39 Ensembl
GRCm386147,042,728 - 147,070,906 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6147,042,764 - 147,073,991 (+)EnsemblGRCm38mm10GRCm38
MGSCv376146,991,292 - 147,019,424 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366146,999,974 - 147,028,071 (+)NCBIMGSCv36mm8
Celera6150,078,704 - 150,106,864 (+)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.7NCBI
Mrps35
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555057,139,870 - 7,181,201 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555057,139,870 - 7,181,201 (-)NCBIChiLan1.0ChiLan1.0
MRPS35
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21069,058,123 - 69,104,222 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11269,054,522 - 69,099,668 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01258,555,661 - 58,600,799 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11261,175,326 - 61,219,680 (-)NCBIpanpan1.1PanPan1.1panPan2
MRPS35
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12719,984,220 - 20,025,734 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2719,984,309 - 20,025,734 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2726,374,570 - 26,415,986 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02720,177,752 - 20,219,604 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2720,172,019 - 20,219,599 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12719,984,550 - 20,026,238 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02720,011,245 - 20,052,931 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02726,531,536 - 26,573,313 (+)NCBIUU_Cfam_GSD_1.0
Mrps35
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213202,571,453 - 202,572,515 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648011,507,692 - 11,509,010 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRPS35
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl545,973,693 - 46,030,453 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1545,973,698 - 46,023,003 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2549,541,791 - 49,591,091 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MRPS35
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11127,432,804 - 27,476,443 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1127,432,871 - 27,476,627 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660697,575,534 - 7,619,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrps35
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624935292,243 - 350,667 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mrps35
248 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:142
Count of miRNA genes:112
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000002520
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat

Markers in Region
RH129064  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24179,987,269 - 179,987,487 (+)MAPPERmRatBN7.2
Rnor_6.04181,463,837 - 181,464,054NCBIRnor6.0
Rnor_5.04245,613,715 - 245,613,932UniSTSRnor5.0
RGSC_v3.44184,671,616 - 184,671,833UniSTSRGSC3.4
Celera4168,480,788 - 168,481,005UniSTS
RH 3.4 Map41090.1UniSTS
Cytogenetic Map4q44UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000002520   ⟹   ENSRNOP00000002520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4179,958,083 - 179,987,710 (+)Ensembl
Rnor_6.0 Ensembl4181,434,812 - 181,465,318 (+)Ensembl
RefSeq Acc Id: NM_001106628   ⟹   NP_001100098
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84181,688,736 - 181,719,403 (+)NCBI
mRatBN7.24179,958,083 - 179,988,752 (+)NCBI
Rnor_6.04181,434,812 - 181,465,318 (+)NCBI
Rnor_5.04245,584,679 - 245,615,196 (+)NCBI
RGSC_v3.44184,642,428 - 184,673,097 (+)RGD
Celera4168,451,594 - 168,482,258 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237676   ⟹   XP_006237738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84181,688,715 - 181,718,175 (+)NCBI
mRatBN7.24179,958,068 - 179,987,522 (+)NCBI
Rnor_6.04181,434,794 - 181,464,089 (+)NCBI
Rnor_5.04245,584,679 - 245,615,196 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237677   ⟹   XP_006237739
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84181,688,720 - 181,718,175 (+)NCBI
mRatBN7.24179,958,067 - 179,987,522 (+)NCBI
Rnor_6.04181,434,793 - 181,464,089 (+)NCBI
Rnor_5.04245,584,679 - 245,615,196 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592600   ⟹   XP_017448089
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84181,688,735 - 181,718,175 (+)NCBI
mRatBN7.24179,958,082 - 179,987,522 (+)NCBI
Rnor_6.04181,434,863 - 181,464,089 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107482   ⟹   XP_038963410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84181,688,715 - 181,718,175 (+)NCBI
mRatBN7.24179,958,093 - 179,987,522 (+)NCBI
RefSeq Acc Id: XM_039107483   ⟹   XP_038963411
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84181,688,720 - 181,718,041 (+)NCBI
mRatBN7.24179,958,067 - 179,987,522 (+)NCBI
RefSeq Acc Id: XM_063285920   ⟹   XP_063141990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84181,688,720 - 181,718,175 (+)NCBI
RefSeq Acc Id: XM_063285921   ⟹   XP_063141991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84181,688,720 - 181,718,175 (+)NCBI
RefSeq Acc Id: NP_001100098   ⟸   NM_001106628
- UniProtKB: D4A9Z6 (UniProtKB/TrEMBL),   A6IN39 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237739   ⟸   XM_006237677
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006237738   ⟸   XM_006237676
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017448089   ⟸   XM_017592600
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000002520   ⟸   ENSRNOT00000002520
RefSeq Acc Id: XP_038963411   ⟸   XM_039107483
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038963410   ⟸   XM_039107482
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063141991   ⟸   XM_063285921
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063141990   ⟸   XM_063285920
- Peptide Label: isoform X4
Protein Domains
Small ribosomal subunit protein mS35 mitochondrial

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9Z6-F1-model_v2 AlphaFold D4A9Z6 1-320 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693510
Promoter ID:EPDNEW_R4034
Type:multiple initiation site
Name:Mrps35_1
Description:mitochondrial ribosomal protein S35
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04181,434,812 - 181,434,872EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306720 AgrOrtholog
BioCyc Gene G2FUF-42419 BioCyc
Ensembl Genes ENSRNOG00000001842 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002520.8 UniProtKB/TrEMBL
InterPro Ribosomal_S24/S35 UniProtKB/TrEMBL
  Ribosomal_S24/S35_mit UniProtKB/TrEMBL
KEGG Report rno:297727 UniProtKB/TrEMBL
NCBI Gene 297727 ENTREZGENE
PANTHER 28S RIBOSOMAL PROTEIN S35, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR13490 UniProtKB/TrEMBL
Pfam MRP-S28 UniProtKB/TrEMBL
PhenoGen Mrps35 PhenoGen
RatGTEx ENSRNOG00000001842 RatGTEx
UniProt A6IN39 ENTREZGENE, UniProtKB/TrEMBL
  D4A9Z6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Mrps35  mitochondrial ribosomal protein S35   Mrps35_predicted  mitochondrial ribosomal protein S35 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mrps35_predicted  mitochondrial ribosomal protein S35 (predicted)      Symbol and Name status set to approved 70820 APPROVED