Rbm43 (RNA binding motif protein 43) - Rat Genome Database

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Pathways
Gene: Rbm43 (RNA binding motif protein 43) Rattus norvegicus
Analyze
Symbol: Rbm43
Name: RNA binding motif protein 43
RGD ID: 1306676
Description: Predicted to enable RNA binding activity. Orthologous to human RBM43 (RNA binding motif protein 43); INTERACTS WITH acetamide; bisphenol A; diuron.
Type: protein-coding (Ensembl: pseudogene)
RefSeq Status: PROVISIONAL
Previously known as: LOC311020; MGC124672; rCG37778-like; RGD1306676; RNA-binding motif protein 43; RNA-binding protein 43; similar to RIKEN cDNA 0610033I05
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2336,394,431 - 36,404,757 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl336,395,346 - 36,404,816 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx339,780,190 - 39,790,346 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0348,364,969 - 48,375,131 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0346,149,553 - 46,159,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0337,434,616 - 37,446,777 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl337,434,620 - 37,445,907 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0342,538,127 - 42,550,678 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4332,938,135 - 32,958,882 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1332,831,292 - 32,855,254 (-)NCBI
Celera334,541,396 - 34,551,624 (-)NCBICelera
Cytogenetic Map3q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334  


Genomics

Comparative Map Data
Rbm43
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2336,394,431 - 36,404,757 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl336,395,346 - 36,404,816 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx339,780,190 - 39,790,346 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0348,364,969 - 48,375,131 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0346,149,553 - 46,159,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0337,434,616 - 37,446,777 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl337,434,620 - 37,445,907 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0342,538,127 - 42,550,678 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4332,938,135 - 32,958,882 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1332,831,292 - 32,855,254 (-)NCBI
Celera334,541,396 - 34,551,624 (-)NCBICelera
Cytogenetic Map3q12NCBI
RBM43
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382151,247,940 - 151,261,863 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2151,247,940 - 151,261,863 (-)EnsemblGRCh38hg38GRCh38
GRCh372152,104,454 - 152,118,377 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362151,814,156 - 151,826,623 (-)NCBINCBI36Build 36hg18NCBI36
Celera2145,718,988 - 145,732,652 (-)NCBICelera
Cytogenetic Map2q23.3NCBI
HuRef2144,001,276 - 144,014,871 (-)NCBIHuRef
CHM1_12152,110,570 - 152,124,230 (-)NCBICHM1_1
T2T-CHM13v2.02151,699,679 - 151,713,604 (-)NCBIT2T-CHM13v2.0
Rbm43
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39251,814,460 - 51,825,175 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl251,814,460 - 51,825,175 (-)EnsemblGRCm39 Ensembl
GRCm38251,924,448 - 51,935,163 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl251,924,448 - 51,935,163 (-)EnsemblGRCm38mm10GRCm38
MGSCv37251,779,968 - 51,790,529 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36251,746,466 - 51,757,172 (-)NCBIMGSCv36mm8
Celera253,648,850 - 53,659,362 (-)NCBICelera
Cytogenetic Map2C1.1NCBI
cM Map229.98NCBI
Rbm43
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544016,837,541 - 16,841,112 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544016,836,877 - 16,843,414 (-)NCBIChiLan1.0ChiLan1.0
RBM43
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12B23,693,560 - 23,708,097 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B8,611,744 - 8,626,269 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B155,783,603 - 155,794,297 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B155,783,924 - 155,788,743 (-)Ensemblpanpan1.1panPan2
Rbm43
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303115,387,055 - 115,397,993 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493646926,219,816 - 26,228,966 (+)EnsemblSpeTri2.0
SpeTri2.0NW_00493646926,219,822 - 26,228,968 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBM43
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11036,681,651 - 36,691,611 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1036,679,830 - 36,686,904 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040162,848,515 - 162,861,660 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbm43
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248664,209,984 - 4,228,185 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248664,212,347 - 4,228,042 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbm43
124 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:453
Count of miRNA genes:251
Interacting mature miRNAs:312
Transcripts:ENSRNOT00000006172
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
731172Bp151Blood pressure QTL 1510.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)31831145447233430Rat
12879849Bw180Body weight QTL 1800.037body mass (VT:0001259)body weight (CMO:0000012)31831145447233430Rat
12879850Cm91Cardiac mass QTL 910.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)31831145447233430Rat
12879851Cm92Cardiac mass QTL 920.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)31831145447233430Rat
12879852Cm93Cardiac mass QTL 930.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)31831145447233430Rat
12879853Am5Aortic mass QTL 50.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)31831145447233430Rat
12879854Kidm63Kidney mass QTL 630.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)31831145447233430Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
1298073Cm13Cardiac mass QTL 132.5heart mass (VT:0007028)heart wet weight (CMO:0000069)32501391138192233Rat
631832Sach1Saccharin preference QTL 12.70.02consumption behavior trait (VT:0002069)calculated saccharin drink intake volume (CMO:0001600)32749462144188411Rat
2313049Bss72Bone structure and strength QTL 722.60.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)32749462150302886Rat
2313076Bss74Bone structure and strength QTL 7420.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)32749462150302886Rat
2313079Bss73Bone structure and strength QTL 731.5tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)32749462150302886Rat
2313093Bmd77Bone mineral density QTL 772.20.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)32749462150302886Rat
2313101Bmd76Bone mineral density QTL 763.60.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)32749462150302886Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1300169Bp177Blood pressure QTL 1772.96arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)33370334761017857Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat

Markers in Region
RH132015  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2336,394,570 - 36,394,758 (+)MAPPERmRatBN7.2
Rnor_6.0337,434,758 - 37,434,945NCBIRnor6.0
Rnor_5.0342,539,472 - 42,539,659UniSTSRnor5.0
RGSC_v3.4332,938,277 - 32,938,464UniSTSRGSC3.4
Celera334,541,538 - 34,541,725UniSTS
RH 3.4 Map3441.0UniSTS
Cytogenetic Map3q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 17 10 18 10 4 21 11
Low 1 43 40 31 1 31 8 11 74 31 20 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000006172   ⟹   ENSRNOP00000006172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl337,434,620 - 37,445,907 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl336,395,346 - 36,404,816 (-)Ensembl
RefSeq Acc Id: NM_001037649   ⟹   NP_001032738
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2336,394,431 - 36,404,757 (-)NCBI
Rnor_6.0337,434,616 - 37,445,907 (-)NCBI
Rnor_5.0342,538,127 - 42,550,678 (-)NCBI
RGSC_v3.4332,938,135 - 32,958,882 (-)RGD
Celera334,541,396 - 34,551,624 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001032738 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI07649 (Get FASTA)   NCBI Sequence Viewer  
  Q3B7D9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001032738   ⟸   NM_001037649
- UniProtKB: Q3B7D9 (UniProtKB/Swiss-Prot),   A6JF12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006172   ⟸   ENSRNOT00000006172
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3B7D9-F1-model_v2 AlphaFold Q3B7D9 1-343 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306676 AgrOrtholog
BioCyc Gene G2FUF-49741 BioCyc
Ensembl Genes ENSRNOG00000004673 Ensembl
  ENSRNOG00000064432 Ensembl
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7930358 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:311020 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124672 IMAGE-MGC_LOAD
NCBI Gene 311020 ENTREZGENE
PANTHER INTERFERON-INDUCED PROTEIN 35/NMI N-MYC/STAT INTERACTING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15225:SF8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rbm43 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP RNA-binding domain, RBD UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A6JF12 ENTREZGENE, UniProtKB/TrEMBL
  Q3B7D9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Rbm43  RNA binding motif protein 43  LOC100363787  rCG37778-like  Data Merged 1643240 APPROVED
2010-05-06 LOC100363787  rCG37778-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-07 Rbm43  RNA binding motif protein 43  RGD1306676  similar to RIKEN cDNA 0610033I05  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1306676  similar to RIKEN cDNA 0610033I05  RGD1306676_predicted  similar to RIKEN cDNA 0610033I05 (predicted)  Symbol and Name status set to approved 1299863 APPROVED
2005-01-20 RGD1306676_predicted  similar to RIKEN cDNA 0610033I05 (predicted)  LOC311020_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC311020_predicted  similar to RIKEN cDNA 0610033I05 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL