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Gene: Zswim6 (zinc finger, SWIM-type containing 6) Rattus norvegicus

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Symbol:

Zswim6

Name:

zinc finger, SWIM-type containing 6

RGD ID:

1306624

Description:

Predicted to be involved in striatal medium spiny neuron differentiation. Predicted to act upstream of or within neuron projection morphogenesis and regulation of neuron migration. Predicted to be located in stereocilium. Predicted to be part of Cul2-RING ubiquitin ligase complex. Human ortholog(s) of this gene implicated in acromelic frontonasal dysostosis. Orthologous to human ZSWIM6 (zinc finger SWIM-type containing 6); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Ab2-064; LOC310062; zinc finger SWIM domain-containing protein 6; zinc finger, SWIM domain containing 6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	40,944,617 - 41,112,340 (-)	NCBI		GRCr8
mRatBN7.2	2	39,211,131 - 39,378,877 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	39,212,949 - 39,378,924 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	38,978,042 - 39,042,886 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	38,979,865 - 39,007,976 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	58,068,503 - 58,133,311 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	38,939,758 - 38,967,874 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	38,858,310 - 39,031,145 (-)	NCBI
Celera	2	35,056,022 - 35,120,828 (-)	NCBI		Celera
Cytogenetic Map	2	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acromelic frontonasal dysostosis (ISO)

epilepsy (ISO)

genetic disease (ISO)

Neurodevelopmental Disorder with Movement Abnormalities, Abnormal Gait, and Autistic Features (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4,4'-trichlorobiphenyl (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

casticin (ISO)

CGP 52608 (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) chloride (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cylindrospermopsin (ISO)

Di-n-octyl phthalate (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fluoranthene (ISO)

folic acid (ISO)

gentamycin (EXP)

indole-3-methanol (EXP)

ketoconazole (ISO)

leflunomide (ISO)

methyl methanesulfonate (ISO)

methylparaben (ISO)

nickel atom (ISO)

okadaic acid (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

phenobarbital (ISO)

quercetin (ISO)

resveratrol (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

neuron projection morphogenesis (ISO)

regulation of neuron migration (ISO)

striatal medium spiny neuron differentiation (ISO)

Cellular Component

Cul2-RING ubiquitin ligase complex (IBA)

membrane (IEA)

stereocilium (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22028030	PMID:25105228	PMID:28433741

Genomics

Comparative Map Data

Zswim6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	40,944,617 - 41,112,340 (-)	NCBI		GRCr8
mRatBN7.2	2	39,211,131 - 39,378,877 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	39,212,949 - 39,378,924 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	38,978,042 - 39,042,886 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	38,979,865 - 39,007,976 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	58,068,503 - 58,133,311 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	38,939,758 - 38,967,874 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	38,858,310 - 39,031,145 (-)	NCBI
Celera	2	35,056,022 - 35,120,828 (-)	NCBI		Celera
Cytogenetic Map	2	q14	NCBI

ZSWIM6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	61,332,258 - 61,546,172 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	61,332,258 - 61,546,172 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	60,628,085 - 60,841,999 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	60,663,758 - 60,877,756 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	57,764,647 - 57,838,148 (+)	NCBI		Celera
Cytogenetic Map	5	q12.1	NCBI
HuRef	5	57,585,234 - 57,798,491 (+)	NCBI		HuRef
CHM1_1	5	60,627,755 - 60,841,658 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	62,151,402 - 62,365,278 (+)	NCBI		T2T-CHM13v2.0

Zswim6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	107,861,152 - 108,026,598 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	107,861,152 - 108,026,598 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	107,724,617 - 107,890,064 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	107,724,617 - 107,890,064 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	108,514,697 - 108,680,258 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	108,845,002 - 109,010,895 (-)	NCBI		MGSCv36	mm8
Celera	13	112,064,904 - 112,230,294 (-)	NCBI		Celera
Cytogenetic Map	13	D2.1	NCBI
cM Map	13	59.39	NCBI

Zswim6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955446	7,011,836 - 7,188,521 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955446	7,010,005 - 7,188,763 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZSWIM6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	52,364,323 - 52,575,529 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	50,517,957 - 50,729,171 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	52,453,762 - 52,664,847 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	54,095,105 - 54,169,700 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	54,096,958 - 54,305,965 (-)	Ensembl	panpan1.1		panPan2

ZSWIM6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	47,954,786 - 48,064,489 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	47,991,716 - 48,063,680 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	44,946,333 - 45,140,308 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	48,347,499 - 48,541,916 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	48,347,407 - 48,540,027 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	45,417,813 - 45,611,848 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	46,204,341 - 46,398,479 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	47,056,413 - 47,250,499 (+)	NCBI		UU_Cfam_GSD_1.0

Zswim6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	198,113,031 - 198,302,567 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936480	7,051,334 - 7,239,677 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936480	7,049,499 - 7,239,035 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZSWIM6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	40,105,227 - 40,305,197 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	40,105,499 - 40,305,379 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	16	43,072,339 - 43,305,396 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZSWIM6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	57,501,906 - 57,717,375 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666049	5,992,635 - 6,209,846 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zswim6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624815	8,482,855 - 8,673,090 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624815	8,481,026 - 8,673,090 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Zswim6
982 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	54
Count of miRNA genes:	52
Interacting mature miRNAs:	54
Transcripts:	ENSRNOT00000064292
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	11591100	56591100	Rat
7387318	Stl32	Serum triglyceride level QTL 32	3.2	0.0003	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	22384627	67384627	Rat
10755436	Coatc8	Coat color QTL 8		0.02431	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	35023117	80023117	Rat
10755434	Coatc7	Coat color QTL 7		0.04794	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	30648065	75648065	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	18960362	228801039	Rat
738010	Lnnr3	Liver neoplastic nodule remodeling QTL 3	2.94		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	2	1	41244106	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1300160	Hrtrt3	Heart rate QTL 3	3.62		heart pumping trait (VT:2000009)	absolute change in heart rate (CMO:0000534)	2	29971593	51729300	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	20304672	65304672	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
152025242	Bw191	Body weight QTL 191	3.62		body mass (VT:0001259)		2	38573329	122609194	Rat
738012	Anxrr3	Anxiety related response QTL 3	3.8		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	2	9023519	54023519	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	25413423	143657569	Rat
9685065	Swd6	Spike wave discharge measurement QTL 6	5.8	0.01	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge rate (CMO:0001739)	2	39223937	48793699	Rat
10402051	Gdil2	Gastrointestinal dilation QTL 2			enteric ganglion morphology trait (VT:0001045)	length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)	2	24903853	74786777	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	27157160	72157160	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26999571	43154682	Rat
731179	Mamtr3	Mammary tumor resistance QTL 3		0.0001	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	32373770	43665178	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1600379	Mcs18	Mammary carcinoma susceptibility QTL 18	2.6		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	7887772	42804738	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1643006	Pain1	Pain QTL 1	3.63	0.005	mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	2	26999571	48268661	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	5873687	102844969	Rat
2300168	Bmd47	Bone mineral density QTL 47	6.6	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	2	20662448	65662448	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	81754745	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	11852062	49003364	Rat
1357990	Ael1	Aortic elastin QTL 1	3.1	0.00091	aorta elastin amount (VT:0003905)	aortic elastin	2	19076825	64076825	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	26917817	136917119	Rat
152025206	Hrtrt23	Heart rate QTL 23	5.98		heart pumping trait (VT:2000009)		2	28484589	169504100	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	16491740	61491740	Rat
152025204	Hrtrt22	Heart rate QTL 22	5.6		heart pumping trait (VT:2000009)		2	28484589	169504100	Rat
61371	Edpm1	Estrogen-dependent pituitary mass QTL 1	4	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	35134841	88029593	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	127469484	Rat

Markers in Region

D2Rat12

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	2	41,107,849 - 41,108,002 (+)	Marker Load Pipeline
mRatBN7.2	2	39,374,376 - 39,374,529 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,141,434 - 39,141,586	NCBI	Rnor6.0
Rnor_5.0	2	58,231,832 - 58,231,984	UniSTS	Rnor5.0
RGSC_v3.4	2	39,101,956 - 39,102,109	RGD	RGSC3.4
RGSC_v3.4	2	39,101,957 - 39,102,109	UniSTS	RGSC3.4
RGSC_v3.1	2	39,022,326 - 39,022,478	RGD
Celera	2	35,219,415 - 35,219,567	UniSTS
RH 3.4 Map	2	177.4	RGD
RH 3.4 Map	2	177.4	UniSTS
RH 2.0 Map	2	54.9	RGD
SHRSP x BN Map	2	16.1598	RGD
FHH x ACI Map	2	24.1699	RGD
Cytogenetic Map	2	q14	UniSTS

D2Got18

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,362,913 - 39,363,105 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,129,825 - 39,130,016	NCBI	Rnor6.0
Rnor_5.0	2	58,220,223 - 58,220,414	UniSTS	Rnor5.0
RGSC_v3.4	2	39,090,543 - 39,090,734	RGD	RGSC3.4
RGSC_v3.4	2	39,090,543 - 39,090,734	UniSTS	RGSC3.4
RGSC_v3.1	2	39,010,912 - 39,011,103	RGD
Celera	2	35,207,961 - 35,208,152	UniSTS
RH 3.4 Map	2	177.1	RGD
RH 3.4 Map	2	177.1	UniSTS
RH 2.0 Map	2	53.8	RGD
Cytogenetic Map	2	q14	UniSTS

D2Got22

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,276,357 - 39,276,596 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,043,267 - 39,043,505	NCBI	Rnor6.0
Rnor_5.0	2	58,133,726 - 58,133,964	UniSTS	Rnor5.0
RGSC_v3.4	2	39,003,165 - 39,003,404	RGD	RGSC3.4
RGSC_v3.4	2	39,003,166 - 39,003,404	UniSTS	RGSC3.4
RGSC_v3.1	2	38,923,535 - 38,923,773	RGD
Celera	2	35,121,209 - 35,121,447	UniSTS
RH 3.4 Map	2	177.1	UniSTS
RH 3.4 Map	2	177.1	RGD
RH 2.0 Map	2	53.8	RGD
Cytogenetic Map	2	q14	UniSTS

BM387016

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,362,737 - 39,362,934 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,129,649 - 39,129,845	NCBI	Rnor6.0
Rnor_5.0	2	58,220,047 - 58,220,243	UniSTS	Rnor5.0
RGSC_v3.4	2	39,090,367 - 39,090,563	UniSTS	RGSC3.4
Celera	2	35,207,785 - 35,207,981	UniSTS
RH 3.4 Map	2	177.2	UniSTS
Cytogenetic Map	2	q14	UniSTS

RH130599

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,211,251 - 39,211,469 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	38,978,163 - 38,978,380	NCBI	Rnor6.0
Rnor_5.0	2	58,068,622 - 58,068,839	UniSTS	Rnor5.0
RGSC_v3.4	2	38,938,061 - 38,938,278	UniSTS	RGSC3.4
Celera	2	35,056,143 - 35,056,360	UniSTS
RH 3.4 Map	2	178.3	UniSTS
Cytogenetic Map	2	q14	UniSTS

RH144303

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,252,855 - 39,253,063 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,019,766 - 39,019,973	NCBI	Rnor6.0
Rnor_5.0	2	58,110,225 - 58,110,432	UniSTS	Rnor5.0
RGSC_v3.4	2	38,979,665 - 38,979,872	UniSTS	RGSC3.4
Celera	2	35,097,762 - 35,097,969	UniSTS
RH 3.4 Map	2	177.3	UniSTS
Cytogenetic Map	2	q14	UniSTS

BI285441

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,356,717 - 39,356,879 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,123,630 - 39,123,791	NCBI	Rnor6.0
Rnor_5.0	2	58,214,028 - 58,214,189	UniSTS	Rnor5.0
RGSC_v3.4	2	39,084,348 - 39,084,509	UniSTS	RGSC3.4
Celera	2	35,201,768 - 35,201,929	UniSTS
RH 3.4 Map	2	176.0	UniSTS
Cytogenetic Map	2	q14	UniSTS

BF397496

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,284,899 - 39,285,051 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,051,804 - 39,051,955	NCBI	Rnor6.0
Rnor_5.0	2	58,142,263 - 58,142,414	UniSTS	Rnor5.0
RGSC_v3.4	2	39,012,607 - 39,012,758	UniSTS	RGSC3.4
Celera	2	35,129,748 - 35,129,899	UniSTS
RH 3.4 Map	2	176.0	UniSTS
Cytogenetic Map	2	q14	UniSTS

AU048211

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,349,916 - 39,350,091 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,116,950 - 39,117,124	NCBI	Rnor6.0
Rnor_5.0	2	58,207,409 - 58,207,583	UniSTS	Rnor5.0
RGSC_v3.4	2	39,077,620 - 39,077,794	UniSTS	RGSC3.4
Celera	2	35,194,729 - 35,194,911	UniSTS
Cytogenetic Map	2	q14	UniSTS

AI008171

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	39,319,895 - 39,320,115 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	39,086,932 - 39,087,151	NCBI	Rnor6.0
Rnor_5.0	2	58,177,391 - 58,177,610	UniSTS	Rnor5.0
RGSC_v3.4	2	39,047,602 - 39,047,821	UniSTS	RGSC3.4
Celera	2	35,164,718 - 35,164,937	UniSTS
RH 3.4 Map	2	175.1	UniSTS
Cytogenetic Map	2	q14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001433121	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001433122	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006224011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760730	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008775059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039103499	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282687	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063282688	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010063737	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY325185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233593	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000064292 ⟹ ENSRNOP00000059251

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	39,212,949 - 39,378,924 (-)	Ensembl
Rnor_6.0 Ensembl	2	38,979,868 - 39,007,976 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078884 ⟹ ENSRNOP00000073696

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	39,212,949 - 39,236,051 (-)	Ensembl
Rnor_6.0 Ensembl	2	38,979,865 - 39,003,552 (-)	Ensembl

RefSeq Acc Id:

XM_039103499 ⟹ XP_038959427

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	40,944,617 - 41,112,339 (-)	NCBI
mRatBN7.2	2	39,211,131 - 39,378,877 (-)	NCBI

RefSeq Acc Id:

XM_063282687 ⟹ XP_063138757

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	40,944,617 - 41,073,996 (-)	NCBI

RefSeq Acc Id:

XM_063282688 ⟹ XP_063138758

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	40,944,617 - 40,968,640 (-)	NCBI

RefSeq Acc Id:

XR_010063737

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	40,954,243 - 41,112,340 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001420050	(Get FASTA)	NCBI Sequence Viewer
	NP_001420051	(Get FASTA)	NCBI Sequence Viewer
	XP_038959427	(Get FASTA)	NCBI Sequence Viewer
	XP_063138757	(Get FASTA)	NCBI Sequence Viewer
	XP_063138758	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAP92586	(Get FASTA)	NCBI Sequence Viewer
	EDM10299	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000059251
	ENSRNOP00000059251.3
	ENSRNOP00000073696.2

Ensembl Acc Id:

ENSRNOP00000059251 ⟸ ENSRNOT00000064292

Ensembl Acc Id:

ENSRNOP00000073696 ⟸ ENSRNOT00000078884

RefSeq Acc Id:	XP_038959427 ⟸ XM_039103499
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063138757 ⟸ XM_063282687
- Peptide Label:	isoform X2
- UniProtKB:	Q7TP63 (UniProtKB/TrEMBL), A6I5J1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138758 ⟸ XM_063282688
- Peptide Label:	isoform X3
- UniProtKB:	Q7TP63 (UniProtKB/TrEMBL), F1M5P6 (UniProtKB/TrEMBL)

Protein Domains

ZSWIM4-8 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TP63-F1-model_v2	AlphaFold	Q7TP63	1-793	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306624	AgrOrtholog
BioCyc Gene	G2FUF-54493	BioCyc
Ensembl Genes	ENSRNOG00000014528	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000064292	ENTREZGENE
	ENSRNOT00000064292.4	UniProtKB/TrEMBL
	ENSRNOT00000078884.2	UniProtKB/TrEMBL
InterPro	ZSWIM4-8_C	UniProtKB/TrEMBL
NCBI Gene	310062	ENTREZGENE
PANTHER	ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6	UniProtKB/TrEMBL
	ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 6	UniProtKB/TrEMBL
Pfam	ZSWIM4-8_C	UniProtKB/TrEMBL
PhenoGen	Zswim6	PhenoGen
RatGTEx	ENSRNOG00000014528	RatGTEx
UniProt	A0A0G2K667_RAT	UniProtKB/TrEMBL
	A6I5J1	ENTREZGENE, UniProtKB/TrEMBL
	F1M5P6	ENTREZGENE, UniProtKB/TrEMBL
	Q7TP63	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-25	Zswim6	zinc finger, SWIM-type containing 6	Zswim6	zinc finger, SWIM domain containing 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Zswim6	zinc finger, SWIM domain containing 6	Zswim6_predicted	zinc finger, SWIM domain containing 6 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Zswim6_predicted	zinc finger, SWIM domain containing 6 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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