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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1315346 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CARMIL1 mRNA | CTD | PMID:22079256 | (1->4)-beta-D-glucan | multiple interactions | ISO | RGD:1315347 | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CARMIL1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1315347 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of LRRC16A mRNA | CTD | PMID:22206623 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | RGD:1315346 | 6480464 | Dihydrotestosterone results in increased expression of LRRC16A mRNA | CTD | PMID:29581250 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | RGD:1315346 | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1315346 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CARMIL1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CARMIL1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1315347 | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of CARMIL1 mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1315347 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CARMIL1 mRNA | CTD | PMID:19933214 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1315347 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CARMIL1 mRNA | CTD | PMID:20702594, PMID:26377647 | 2,4,6-tribromophenol | decreases expression | ISO | RGD:1315346 | 6480464 | 2 more ... | CTD | PMID:31675489 | 2-methoxyethanol | increases expression | EXP | | 6480464 | methyl cellosolve results in increased expression of CARMIL1 mRNA | CTD | PMID:21061450 | 3,3',4,4',5-pentachlorobiphenyl | affects expression | ISO | RGD:1315347 | 6480464 | 3 more ... | CTD | PMID:20702594 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | RGD:1315346 | 6480464 | tetrabromobisphenol A results in decreased expression of CARMIL1 protein | CTD | PMID:31675489 | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of CARMIL1 protein | CTD | PMID:34915118 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | RGD:1315347 | 6480464 | bis(4-hydroxyphenyl)sulfone results in decreased methylation of CARMIL1 exon | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1315347 | 6480464 | Fenretinide results in increased expression of CARMIL1 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of CARMIL1 mRNA | CTD | PMID:24780913 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of CARMIL1 mRNA | CTD | PMID:31881176 | aflatoxin B1 | decreases methylation | ISO | RGD:1315346 | 6480464 | Aflatoxin B1 results in decreased methylation of CARMIL1 gene | CTD | PMID:27153756 | aflatoxin B1 | affects methylation | ISO | RGD:1315346 | 6480464 | Aflatoxin B1 affects the methylation of LRRC16A intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | RGD:1315346 | 6480464 | Tretinoin results in decreased expression of LRRC16A mRNA | CTD | PMID:33167477 | aristolochic acid A | decreases expression | ISO | RGD:1315346 | 6480464 | aristolochic acid I results in decreased expression of CARMIL1 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | RGD:1315346 | 6480464 | Arsenic affects the methylation of CARMIL1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1315346 | 6480464 | Arsenic affects the methylation of CARMIL1 gene | CTD | PMID:25304211 | benzo[a]pyrene | decreases expression | ISO | RGD:1315346 | 6480464 | Benzo(a)pyrene results in decreased expression of CARMIL1 mRNA | CTD | PMID:20064835 | benzo[a]pyrene | affects methylation | ISO | RGD:1315346 | 6480464 | Benzo(a)pyrene affects the methylation of LRRC16A intron, Benzo(a)pyrene affects the methylation of LRRC16A promoter | CTD | PMID:27901495, PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | RGD:1315346 | 6480464 | Benzo(a)pyrene results in increased methylation of LRRC16A 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | RGD:1315347 | 6480464 | Benzo(a)pyrene results in decreased expression of CARMIL1 mRNA | CTD | PMID:19770486 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1315346 | 6480464 | 7 more ... | CTD | PMID:19150397, PMID:20018196 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CARMIL1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | RGD:1315346 | 6480464 | bisphenol A results in decreased expression of CARMIL1 protein | CTD | PMID:31675489 | bisphenol F | multiple interactions | ISO | RGD:1315346 | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of CARMIL1 gene | CTD | PMID:31601247 | butanal | decreases expression | ISO | RGD:1315346 | 6480464 | butyraldehyde results in decreased expression of CARMIL1 mRNA | CTD | PMID:26079696 | caffeine | affects phosphorylation | ISO | RGD:1315346 | 6480464 | Caffeine affects the phosphorylation of CARMIL1 protein | CTD | PMID:35688186 | calcitriol | multiple interactions | ISO | RGD:1315346 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of CARMIL1 mRNA | CTD | PMID:21592394 | calcitriol | increases expression | ISO | RGD:1315346 | 6480464 | Calcitriol results in increased expression of CARMIL1 mRNA | CTD | PMID:21592394 | captan | increases expression | ISO | RGD:1315347 | 6480464 | Captan results in increased expression of LRRC16A mRNA | CTD | PMID:31558096 | chloroprene | increases expression | ISO | RGD:1315347 | 6480464 | Chloroprene results in increased expression of CARMIL1 mRNA | CTD | PMID:23125180 | chrysene | decreases expression | ISO | RGD:1315347 | 6480464 | chrysene results in decreased expression of CARMIL1 mRNA | CTD | PMID:26377693 | ciguatoxin CTX1B | affects expression | ISO | RGD:1315347 | 6480464 | Ciguatoxins affects the expression of CARMIL1 mRNA | CTD | PMID:18353800 | clothianidin | decreases expression | ISO | RGD:1315346 | 6480464 | clothianidin results in decreased expression of LRRC16A mRNA | CTD | PMID:31626844 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of CARMIL1 mRNA | CTD | PMID:24386269 | coumarin | increases phosphorylation | ISO | RGD:1315346 | 6480464 | coumarin results in increased phosphorylation of CARMIL1 protein | CTD | PMID:35688186 | crocidolite asbestos | affects expression | ISO | RGD:1315347 | 6480464 | Asbestos, Crocidolite affects the expression of CARMIL1 mRNA | CTD | PMID:29279043 | cytarabine | decreases expression | ISO | RGD:1315346 | 6480464 | Cytarabine results in decreased expression of CARMIL1 mRNA | CTD | PMID:21198554 | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of CARMIL1 mRNA | CTD | PMID:23914054 | deguelin | decreases expression | ISO | RGD:1315346 | 6480464 | deguelin results in decreased expression of CARMIL1 mRNA | CTD | PMID:33512557 | dichloroacetic acid | decreases expression | ISO | RGD:1315347 | 6480464 | Dichloroacetic Acid results in decreased expression of CARMIL1 mRNA | CTD | PMID:28962523 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of CARMIL1 mRNA | CTD | PMID:21551480 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CARMIL1 mRNA | CTD | PMID:29391264 | epoxiconazole | decreases expression | ISO | RGD:1315347 | 6480464 | epoxiconazole results in decreased expression of CARMIL1 mRNA | CTD | PMID:35436446 | Erionite | decreases expression | ISO | RGD:1315347 | 6480464 | erionite results in decreased expression of CARMIL1 mRNA | CTD | PMID:29279043 | ethanol | increases expression | ISO | RGD:1315347 | 6480464 | Ethanol results in increased expression of LRRC16A mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | RGD:1315346 | 6480464 | Ethyl Methanesulfonate results in increased expression of CARMIL1 mRNA | CTD | PMID:23649840 | folpet | increases expression | ISO | RGD:1315347 | 6480464 | folpet results in increased expression of LRRC16A mRNA | CTD | PMID:31558096 | formaldehyde | increases expression | ISO | RGD:1315346 | 6480464 | Formaldehyde results in increased expression of CARMIL1 mRNA | CTD | PMID:23649840 | fulvestrant | multiple interactions | ISO | RGD:1315346 | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of CARMIL1 gene | CTD | PMID:31601247 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of CARMIL1 mRNA | CTD | PMID:25539665, PMID:27387713 | inulin | multiple interactions | ISO | RGD:1315347 | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CARMIL1 mRNA | CTD | PMID:36331819 | isoprenaline | increases expression | ISO | RGD:1315347 | 6480464 | Isoproterenol results in increased expression of CARMIL1 mRNA | CTD | PMID:20003209 | ivermectin | decreases expression | ISO | RGD:1315346 | 6480464 | Ivermectin results in decreased expression of CARMIL1 protein | CTD | PMID:32959892 | ketoconazole | decreases expression | ISO | RGD:1315346 | 6480464 | Ketoconazole results in decreased expression of CARMIL1 mRNA | CTD | PMID:36621641 | methyl methanesulfonate | increases expression | ISO | RGD:1315346 | 6480464 | Methyl Methanesulfonate results in increased expression of CARMIL1 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | RGD:1315346 | 6480464 | methylmercuric chloride results in decreased expression of CARMIL1 mRNA | CTD | PMID:28001369 | nickel sulfate | increases expression | ISO | RGD:1315346 | 6480464 | nickel sulfate results in increased expression of CARMIL1 mRNA | CTD | PMID:22714537 | ozone | increases expression | ISO | RGD:1315347 | 6480464 | Ozone results in increased expression of CARMIL1 mRNA | CTD | PMID:31626304 | paracetamol | decreases expression | ISO | RGD:1315346 | 6480464 | Acetaminophen results in decreased expression of CARMIL1 mRNA | CTD | PMID:21420995 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CARMIL1 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | RGD:1315347 | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CARMIL1 mRNA, [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of CARMIL1 mRNA | CTD | PMID:36331819 | phenobarbital | increases expression | ISO | RGD:1315347 | 6480464 | Phenobarbital results in increased expression of CARMIL1 mRNA | CTD | PMID:19270015 | phenobarbital | decreases expression | ISO | RGD:1315347 | 6480464 | Phenobarbital results in decreased expression of CARMIL1 mRNA | CTD | PMID:23091169 | picoxystrobin | decreases expression | ISO | RGD:1315346 | 6480464 | picoxystrobin results in decreased expression of CARMIL1 mRNA | CTD | PMID:33512557 | pirinixic acid | increases expression | ISO | RGD:1315347 | 6480464 | pirinixic acid results in increased expression of CARMIL1 mRNA | CTD | PMID:18445702 | pirinixic acid | decreases expression | ISO | RGD:1315347 | 6480464 | pirinixic acid results in decreased expression of CARMIL1 mRNA | CTD | PMID:23811191 | potassium chromate | decreases expression | ISO | RGD:1315346 | 6480464 | potassium chromate(VI) results in decreased expression of CARMIL1 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | RGD:1315346 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of CARMIL1 mRNA | CTD | PMID:22079256 | silicon dioxide | decreases expression | ISO | RGD:1315346 | 6480464 | Silicon Dioxide analog results in decreased expression of CARMIL1 mRNA | CTD | PMID:25895662 | sodium arsenite | increases expression | ISO | RGD:1315346 | 6480464 | sodium arsenite results in increased expression of CARMIL1 mRNA | CTD | PMID:22714537 | sodium dichromate | increases expression | ISO | RGD:1315347 | 6480464 | sodium bichromate results in increased expression of LRRC16A mRNA | CTD | PMID:31558096 | sulforaphane | decreases expression | ISO | RGD:1315347 | 6480464 | sulforaphane results in decreased expression of CARMIL1 mRNA | CTD | PMID:30529165 | tamoxifen | affects expression | ISO | RGD:1315347 | 6480464 | Tamoxifen affects the expression of CARMIL1 mRNA | CTD | PMID:20937368 | testosterone | increases expression | ISO | RGD:1315346 | 6480464 | Testosterone results in increased expression of CARMIL1 mRNA | CTD | PMID:21592394 | testosterone | increases expression | ISO | RGD:1315347 | 6480464 | Testosterone results in increased expression of CARMIL1 mRNA | CTD | PMID:21669218 | testosterone | multiple interactions | ISO | RGD:1315346 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of CARMIL1 mRNA | CTD | PMID:21592394 | tetrachloroethene | decreases expression | ISO | RGD:1315347 | 6480464 | Tetrachloroethylene results in decreased expression of CARMIL1 mRNA | CTD | PMID:28973375 | tetrachloromethane | decreases expression | ISO | RGD:1315347 | 6480464 | Carbon Tetrachloride results in decreased expression of CARMIL1 mRNA | CTD | PMID:27339419 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CARMIL1 mRNA | CTD | PMID:23411599 | Triptolide | decreases expression | ISO | RGD:1315347 | 6480464 | triptolide results in decreased expression of LRRC16A mRNA | CTD | PMID:32835833 | valproic acid | increases expression | ISO | RGD:1315346 | 6480464 | Valproic Acid results in increased expression of CARMIL1 mRNA | CTD | PMID:23179753, PMID:28001369 | valproic acid | affects expression | ISO | RGD:1315347 | 6480464 | Valproic Acid affects the expression of CARMIL1 mRNA | CTD | PMID:17292431 | |