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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Dnaja3 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Dnaja3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of DNAJA3 mRNA | CTD | PMID:36331819 | Dnaja3 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in increased expression of DNAJA3 mRNA | CTD | PMID:22206623 | Dnaja3 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Dnaja3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of DNAJA3 mRNA | CTD | PMID:17942748 | Dnaja3 | Rat | 17beta-estradiol | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | Estradiol promotes the reaction [DNAJA3 protein binds to ESR1 protein] | CTD | PMID:27156127 | Dnaja3 | Rat | 17beta-estradiol | increases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Estradiol results in increased expression of DNAJA3 mRNA | CTD | PMID:31614463 | Dnaja3 | Rat | 17beta-estradiol | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Estradiol results in increased expression of DNAJA3 mRNA | CTD | PMID:39298647 | Dnaja3 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of DNAJA3 mRNA | CTD | PMID:31826744|PMID:32679240 | Dnaja3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Dnaja3 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of DNAJA3 mRNA | CTD | PMID:17942748 | Dnaja3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DNAJA3 mRNA | CTD | PMID:21570461 | Dnaja3 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DNAJA3 mRNA | CTD | PMID:21215274 | Dnaja3 | Rat | 2-methylcholine | affects expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of DNAJA3 mRNA | CTD | PMID:21179406 | Dnaja3 | Rat | 4,4'-sulfonyldiphenol | affects expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | bisphenol S affects the expression of DNAJA3 protein | CTD | PMID:31945527 | Dnaja3 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | bisphenol S results in increased expression of DNAJA3 mRNA | CTD | PMID:39298647 | Dnaja3 | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of DNAJA3 mRNA | CTD | PMID:31881176 | Dnaja3 | Rat | acrolein | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Dnaja3 | Rat | aflatoxin B1 | decreases methylation | ISO | DNAJA3 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of DNAJA3 intron | CTD | PMID:30157460 | Dnaja3 | Rat | all-trans-retinoic acid | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DNAJA3 mRNA | CTD | PMID:33167477 | Dnaja3 | Rat | alpha-pinene | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Dnaja3 | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of DNAJA3 mRNA | CTD | PMID:30779732 | Dnaja3 | Rat | atrazine | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of DNAJA3 mRNA | CTD | PMID:22378314 | Dnaja3 | Rat | benzo[a]pyrene | multiple interactions | ISO | Dnaja3 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of DNAJA3 mRNA] | CTD | PMID:22228805 | Dnaja3 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DNAJA3 mRNA | CTD | PMID:19150397 | Dnaja3 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DNAJA3 mRNA | CTD | PMID:25181051 | Dnaja3 | Rat | bisphenol A | affects expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | bisphenol A affects the expression of DNAJA3 mRNA | CTD | PMID:30903817 | Dnaja3 | Rat | cadmium dichloride | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of DNAJA3 mRNA | CTD | PMID:38568856 | Dnaja3 | Rat | carbamazepine | affects expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of DNAJA3 mRNA | CTD | PMID:24752500 | Dnaja3 | Rat | carbon nanotube | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in increased expression of DNAJA3 mRNA | CTD | PMID:25620056 | Dnaja3 | Rat | clozapine | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Clozapine] results in increased expression of DNAJA3 protein | CTD | PMID:34122009 | Dnaja3 | Rat | copper(II) sulfate | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of DNAJA3 mRNA | CTD | PMID:19549813 | Dnaja3 | Rat | Cuprizon | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Cuprizone co-treated with Clozapine] results in increased expression of DNAJA3 protein | CTD | PMID:34122009 | Dnaja3 | Rat | Cuprizon | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Cuprizone results in decreased expression of DNAJA3 protein | CTD | PMID:34122009 | Dnaja3 | Rat | cylindrospermopsin | increases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of DNAJA3 mRNA | CTD | PMID:24921660 | Dnaja3 | Rat | Dibutyl phosphate | affects expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of DNAJA3 mRNA | CTD | PMID:37042841 | Dnaja3 | Rat | diclofenac | affects expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Diclofenac affects the expression of DNAJA3 mRNA | CTD | PMID:24752500 | Dnaja3 | Rat | diclofenac | decreases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Diclofenac results in decreased expression of DNAJA3 mRNA | CTD | PMID:26934552 | Dnaja3 | Rat | diquat | decreases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Diquat results in decreased expression of DNAJA3 protein | CTD | PMID:36851058 | Dnaja3 | Rat | doxorubicin | decreases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of DNAJA3 mRNA | CTD | PMID:26873546 | Dnaja3 | Rat | elemental selenium | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DNAJA3 mRNA | CTD | PMID:19244175 | Dnaja3 | Rat | elemental selenium | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Selenium results in decreased expression of DNAJA3 mRNA | CTD | PMID:19244175 | Dnaja3 | Rat | fenofibrate | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Fenofibrate results in increased expression of DNAJA3 mRNA | CTD | PMID:21318169 | Dnaja3 | Rat | fenthion | decreases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Fenthion results in decreased expression of DNAJA3 mRNA | CTD | PMID:34813904 | Dnaja3 | Rat | flutamide | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Flutamide results in increased expression of DNAJA3 mRNA | CTD | PMID:17702527 | Dnaja3 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of DNAJA3 mRNA | CTD | PMID:20566332 | Dnaja3 | Rat | flutamide | decreases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Flutamide results in decreased expression of DNAJA3 mRNA | CTD | PMID:19442681 | Dnaja3 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of DNAJA3 mRNA | CTD | PMID:26194646 | Dnaja3 | Rat | gold atom | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Polyethyleneimine binds to Gold] which results in increased expression of DNAJA3 mRNA | CTD | PMID:28433809 | Dnaja3 | Rat | gold(0) | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Polyethyleneimine binds to Gold] which results in increased expression of DNAJA3 mRNA | CTD | PMID:28433809 | Dnaja3 | Rat | hydralazine | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of DNAJA3 mRNA | CTD | PMID:17183730 | Dnaja3 | Rat | isotretinoin | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of DNAJA3 mRNA | CTD | PMID:20436886 | Dnaja3 | Rat | ivermectin | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DNAJA3 protein | CTD | PMID:32959892 | Dnaja3 | Rat | lamivudine | multiple interactions | ISO | Dnaja3 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine] results in decreased expression of DNAJA3 mRNA | CTD | PMID:18313992 | Dnaja3 | Rat | lead(0) | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Lead results in decreased expression of DNAJA3 mRNA | CTD | PMID:19921347 | Dnaja3 | Rat | manganese atom | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in decreased expression of DNAJA3 more ... | CTD | PMID:39836092 | Dnaja3 | Rat | manganese(0) | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in decreased expression of DNAJA3 more ... | CTD | PMID:39836092 | Dnaja3 | Rat | manganese(II) chloride | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in decreased expression of DNAJA3 more ... | CTD | PMID:39836092 | Dnaja3 | Rat | methidathion | affects expression | ISO | Dnaja3 (Mus musculus) | 6480464 | methidathion affects the expression of DNAJA3 mRNA | CTD | PMID:34813904 | Dnaja3 | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of DNAJA3 protein | CTD | PMID:22016808 | Dnaja3 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of DNAJA3 mRNA | CTD | PMID:24136188 | Dnaja3 | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of DNAJA3 mRNA | CTD | PMID:24136188 | Dnaja3 | Rat | nitrates | multiple interactions | ISO | Dnaja3 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of DNAJA3 more ... | CTD | PMID:35964746 | Dnaja3 | Rat | ouabain | increases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Ouabain results in increased expression of DNAJA3 mRNA | CTD | PMID:28795476 | Dnaja3 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DNAJA3 mRNA | CTD | PMID:25729387 | Dnaja3 | Rat | oxidopamine | increases degradation | EXP | | 6480464 | Oxidopamine results in increased degradation of DNAJA3 protein | CTD | PMID:22016808 | Dnaja3 | Rat | oxidopamine | decreases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Oxidopamine results in decreased expression of DNAJA3 protein | CTD | PMID:22016808 | Dnaja3 | Rat | ozone | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of more ... | CTD | PMID:32699268 | Dnaja3 | Rat | paracetamol | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of DNAJA3 mRNA | CTD | PMID:25704631 | Dnaja3 | Rat | perfluorononanoic acid | increases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of DNAJA3 mRNA | CTD | PMID:32588087 | Dnaja3 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Dnaja3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of DNAJA3 mRNA | CTD | PMID:36331819 | Dnaja3 | Rat | phlorizin | decreases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Phlorhizin results in decreased expression of DNAJA3 mRNA | CTD | PMID:22538082 | Dnaja3 | Rat | pirinixic acid | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of DNAJA3 mRNA | CTD | PMID:18301758 | Dnaja3 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of DNAJA3 mRNA | CTD | PMID:28903501 | Dnaja3 | Rat | selenium atom | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DNAJA3 mRNA | CTD | PMID:19244175 | Dnaja3 | Rat | selenium atom | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Selenium results in decreased expression of DNAJA3 mRNA | CTD | PMID:19244175 | Dnaja3 | Rat | sodium arsenite | increases expression | ISO | Dnaja3 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of DNAJA3 mRNA | CTD | PMID:16014739 | Dnaja3 | Rat | sunitinib | increases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of DNAJA3 mRNA | CTD | PMID:31533062 | Dnaja3 | Rat | thapsigargin | increases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of DNAJA3 mRNA | CTD | PMID:22378314 | Dnaja3 | Rat | thiram | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Thiram results in decreased expression of DNAJA3 mRNA | CTD | PMID:38568856 | Dnaja3 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of DNAJA3 mRNA | CTD | PMID:25729387 | Dnaja3 | Rat | triphenyl phosphate | affects expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of DNAJA3 mRNA | CTD | PMID:37042841 | Dnaja3 | Rat | triptonide | affects expression | ISO | Dnaja3 (Mus musculus) | 6480464 | triptonide affects the expression of DNAJA3 mRNA | CTD | PMID:33045310 | Dnaja3 | Rat | tunicamycin | increases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of DNAJA3 mRNA | CTD | PMID:22378314 | Dnaja3 | Rat | urethane | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Urethane results in decreased expression of DNAJA3 mRNA | CTD | PMID:28818685 | Dnaja3 | Rat | valproic acid | increases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of DNAJA3 mRNA | CTD | PMID:29154799 | Dnaja3 | Rat | valproic acid | affects expression | ISO | Dnaja3 (Mus musculus) | 6480464 | Valproic Acid affects the expression of DNAJA3 mRNA | CTD | PMID:17292431 | Dnaja3 | Rat | valproic acid | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of DNAJA3 mRNA | CTD | PMID:17183730 | Dnaja3 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of DNAJA3 gene | CTD | PMID:31682807 | Dnaja3 | Rat | vitamin E | multiple interactions | ISO | DNAJA3 (Homo sapiens) | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of DNAJA3 mRNA | CTD | PMID:19244175 | Dnaja3 | Rat | vitamin E | decreases expression | ISO | DNAJA3 (Homo sapiens) | 6480464 | Vitamin E results in decreased expression of DNAJA3 mRNA | CTD | PMID:19244175 | Dnaja3 | Rat | zidovudine | multiple interactions | ISO | Dnaja3 (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine] results in decreased expression of DNAJA3 mRNA | CTD | PMID:18313992 | |