Ifitm3-ps2 (interferon induced transmembrane protein 3, pseudogene 2) - Rat Genome Database

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Gene: Ifitm3-ps2 (interferon induced transmembrane protein 3, pseudogene 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ifitm3-ps2 (Ensembl: Ifitm7)
Name: interferon induced transmembrane protein 3, pseudogene 2 (Ensembl:interferon induced transmembrane protein 7)
RGD ID: 1306466
Description: Predicted to be involved in several processes, including defense response to other organism; negative regulation of viral genome replication; and response to interferon-alpha. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFITM3 (interferon induced transmembrane protein 3); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon.
Type: pseudo (Ensembl: protein-coding)
RefSeq Status: INFERRED
Previously known as: Ifitm7; interferon induced transmembrane protein 7; interferon-induced transmembrane protein 3; LOC288244
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Related Functional Gene: Ifitm3  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81146,606,814 - 46,607,230 (+)NCBIGRCr8
mRatBN7.21133,137,146 - 33,137,562 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1133,137,146 - 33,138,061 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01134,037,103 - 34,037,519 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1134,037,104 - 34,037,513 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01137,626,720 - 37,627,136 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41134,046,822 - 34,047,238 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11134,103,064 - 34,103,481 (+)NCBI
Celera1135,307,327 - 35,307,743 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:23166625  


Genomics

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:67
Count of miRNA genes:56
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000039434
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
4 8 14 17 14 6 5 6 4 31 19 5 2 17 8

Sequence


Ensembl Acc Id: ENSRNOT00000039434
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1133,137,146 - 33,138,061 (+)Ensembl
Rnor_6.0 Ensembl1134,037,104 - 34,037,513 (+)Ensembl
RefSeq Acc Id: XM_221637   ⟹   XP_221637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81146,606,814 - 46,607,230 (+)NCBI
mRatBN7.21133,137,146 - 33,137,562 (+)NCBI
Rnor_6.01134,037,103 - 34,037,519 (+)NCBI
Rnor_5.01137,626,720 - 37,627,136 (+)NCBI
RGSC_v3.41134,046,822 - 34,047,238 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_221637 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000085507
  ENSRNOP00000085507.1
RefSeq Acc Id: XP_221637   ⟸   XM_221637
- Sequence:

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-21786 BioCyc
Ensembl Genes ENSRNOG00000021674 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000039434 ENTREZGENE
  ENSRNOT00000039434.6 UniProtKB/TrEMBL
InterPro CD225/Dispanin_fam UniProtKB/TrEMBL
  IFITM_antiviral_protein UniProtKB/TrEMBL
NCBI Gene 288244 ENTREZGENE
PANTHER INTERFERON INDUCIBLE TRANSMEMBRANE PROTEIN UniProtKB/TrEMBL
  INTERFERON-INDUCED TRANSMEMBRANE PROTEIN 3 UniProtKB/TrEMBL
Pfam CD225 UniProtKB/TrEMBL
PhenoGen Ifitm3-ps2 PhenoGen
RatGTEx ENSRNOG00000021674 RatGTEx
UniProt A0A8I6A2F8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2025-02-06 Ifitm3-ps2  interferon induced transmembrane protein 3, pseudogene 2  Ifitm3-ps2  interferon induced transmembrane protein3, pseudogene 2  Name changed 629549 APPROVED
2024-08-05 Ifitm3-ps2  interferon induced transmembrane protein3, pseudogene 2  Ifitm7  interferon induced transmembrane protein 7  Name and Symbol and Type changed (type changed from [protein-coding] to [pseudo]) 629549 APPROVED
2008-04-30 Ifitm7  interferon induced transmembrane protein 7   Ifitm7_predicted  interferon induced transmembrane protein 7 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ifitm7_predicted  interferon induced transmembrane protein 7 (predicted)      Symbol and Name status set to approved 70820 APPROVED