Asb2 (ankyrin repeat and SOCS box-containing 2) - Rat Genome Database

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Gene: Asb2 (ankyrin repeat and SOCS box-containing 2) Rattus norvegicus
Analyze
Symbol: Asb2
Name: ankyrin repeat and SOCS box-containing 2
RGD ID: 1306414
Description: Predicted to enable cullin family protein binding activity. Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in several processes, including heart development; podosome assembly; and skeletal muscle atrophy. Predicted to act upstream of or within skeletal muscle cell differentiation. Predicted to be located in Z disc. Predicted to be part of ubiquitin ligase complex. Orthologous to human ASB2 (ankyrin repeat and SOCS box containing 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ankyrin repeat and SOCS box protein 2; ankyrin repeat and SOCS box protein 2-like; ankyrin repeat and SOCS box-containing protein 2; ASB-2; LOC100909439; LOC299266
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,239,550 - 128,275,833 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6128,239,552 - 128,266,321 (-)EnsemblGRCr8
mRatBN7.26122,474,754 - 122,511,014 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,474,756 - 122,510,854 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6122,615,834 - 122,651,778 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,911,098 - 122,947,036 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,245,566 - 122,281,575 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,212,325 - 127,248,451 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,212,273 - 127,248,372 (-)Ensemblrn6Rnor6.0
Rnor_5.06136,425,783 - 136,469,502 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46127,609,500 - 127,645,492 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6119,956,026 - 119,991,593 (-)NCBICelera
RGSC_v3.16127,613,248 - 127,649,239 (-)NCBI
Cytogenetic Map6q32NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-trinitrotoluene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-azacytidine  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
aristolochic acid A  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
butanal  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
cantharidin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
fenthion  (ISO)
genistein  (ISO)
GSK-J4  (ISO)
GW 4064  (ISO)
hexadecanoic acid  (ISO)
irinotecan  (EXP)
lead(0)  (ISO)
methapyrilene  (ISO)
methidathion  (ISO)
Muraglitazar  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
nitrofen  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
pentanal  (ISO)
perfluorooctanoic acid  (EXP)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
tamibarotene  (ISO)
Tesaglitazar  (EXP)
tetrachloroethene  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (EXP)
Tungsten carbide  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:16325183   PMID:19300455   PMID:22147266  


Genomics

Comparative Map Data
Asb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86128,239,550 - 128,275,833 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl6128,239,552 - 128,266,321 (-)EnsemblGRCr8
mRatBN7.26122,474,754 - 122,511,014 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6122,474,756 - 122,510,854 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx6122,615,834 - 122,651,778 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06122,911,098 - 122,947,036 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06122,245,566 - 122,281,575 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.06127,212,325 - 127,248,451 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6127,212,273 - 127,248,372 (-)Ensemblrn6Rnor6.0
Rnor_5.06136,425,783 - 136,469,502 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.46127,609,500 - 127,645,492 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera6119,956,026 - 119,991,593 (-)NCBICelera
RGSC_v3.16127,613,248 - 127,649,239 (-)NCBI
Cytogenetic Map6q32NCBI
ASB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381493,934,166 - 93,976,570 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1493,933,783 - 93,978,831 (-)Ensemblhg38GRCh38
GRCh371494,400,512 - 94,442,916 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361493,470,266 - 93,493,520 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341493,470,265 - 93,493,520NCBI
Celera1474,454,282 - 74,477,544 (-)NCBICelera
Cytogenetic Map14q32.12NCBI
HuRef1474,580,269 - 74,622,812 (-)NCBIHuRef
CHM1_11494,338,550 - 94,381,110 (-)NCBICHM1_1
T2T-CHM13v2.01488,161,475 - 88,203,881 (-)NCBIT2T-CHM13v2.0
Asb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912103,287,401 - 103,322,260 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12103,287,401 - 103,322,260 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm3812103,321,142 - 103,356,001 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12103,321,142 - 103,356,001 (-)Ensemblmm10GRCm38
MGSCv3712104,559,352 - 104,594,211 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3612103,722,192 - 103,757,051 (-)NCBIMGSCv36mm8
Celera12104,538,189 - 104,572,686 (-)NCBICelera
Cytogenetic Map12ENCBI
cM Map1252.9NCBI
Asb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543816,005,570 - 16,042,115 (-)Ensembl
ChiLan1.0NW_00495543816,005,570 - 16,041,668 (-)NCBIChiLan1.0ChiLan1.0
ASB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21595,091,860 - 95,134,193 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11494,308,365 - 94,350,698 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01474,566,607 - 74,608,905 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11493,900,425 - 93,942,764 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1493,900,914 - 93,930,527 (-)EnsemblpanPan2panpan1.1
ASB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1863,008,206 - 63,051,809 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl863,008,575 - 63,051,581 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha862,585,084 - 62,628,410 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0863,279,448 - 63,322,854 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl863,277,026 - 63,322,847 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1862,957,212 - 63,000,493 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0863,008,327 - 63,051,686 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0863,338,505 - 63,381,859 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Asb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864011,617,225 - 11,653,472 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367331,813,548 - 1,849,806 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367331,813,569 - 1,849,805 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7115,210,891 - 115,258,960 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.17115,210,885 - 115,258,863 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27121,998,766 - 122,044,049 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12471,687,282 - 71,730,684 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2471,687,238 - 71,730,696 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605358,925,221 - 58,968,980 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Asb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473410,316,299 - 10,352,515 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473410,317,932 - 10,352,300 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Asb2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v17114,608,866 - 114,644,279 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Asb2
332 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:263
Count of miRNA genes:161
Interacting mature miRNAs:186
Transcripts:ENSRNOT00000012045
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6112483610147156653Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6114241077147156653Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)668767270135411972Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)688019181136741135Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)690871046135871046Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)693560258136550638Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)698944780143944780Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)6100704576136029228Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6110921244147156653Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)679198463144254945Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6106095977147156653Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)693778632138778632Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)684490437129490437Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)690871046135871046Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)693560258136550638Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6118366855147156653Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6101593607138161926Rat
1298087Iddm18Insulin dependent diabetes mellitus QTL 180.0001urine glucose amount (VT:0001758)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)6122236101147156653Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)693560258136550638Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)6101593607146593607Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6121444670147156653Rat

Markers in Region
BG375800  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26122,487,793 - 122,487,893 (+)MAPPERmRatBN7.2
Rnor_6.06127,225,365 - 127,225,464NCBIRnor6.0
Rnor_5.06136,438,858 - 136,438,957UniSTSRnor5.0
RGSC_v3.46127,622,540 - 127,622,639UniSTSRGSC3.4
Celera6119,969,098 - 119,969,197UniSTS
RH 3.4 Map6843.79UniSTS
Cytogenetic Map6q32UniSTS
RH139118  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26122,500,833 - 122,500,983 (+)MAPPERmRatBN7.2
Rnor_6.06127,238,227 - 127,238,376NCBIRnor6.0
Rnor_5.06136,453,502 - 136,453,651UniSTSRnor5.0
Rnor_5.06136,451,522 - 136,451,671UniSTSRnor5.0
RGSC_v3.46127,635,425 - 127,635,574UniSTSRGSC3.4
Celera6119,981,896 - 119,982,045UniSTS
RH 3.4 Map6840.19UniSTS
Cytogenetic Map6q32UniSTS
RH136912  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26122,474,775 - 122,474,988 (+)MAPPERmRatBN7.2
Rnor_6.06128,984,736 - 128,984,948NCBIRnor6.0
Rnor_6.06127,212,347 - 127,212,559NCBIRnor6.0
Rnor_5.06138,181,837 - 138,182,049UniSTSRnor5.0
Rnor_5.06136,425,805 - 136,426,017UniSTSRnor5.0
RGSC_v3.46127,609,522 - 127,609,734UniSTSRGSC3.4
Celera6119,956,048 - 119,956,260UniSTS
RH 3.4 Map6841.9UniSTS
Cytogenetic Map6q32UniSTS
Cytogenetic Map12q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 88 59 6 352 188 11 135 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000085517   ⟹   ENSRNOP00000071182
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6128,239,552 - 128,266,321 (-)Ensembl
mRatBN7.2 Ensembl6122,474,756 - 122,510,854 (-)Ensembl
Rnor_6.0 Ensembl6127,212,273 - 127,248,372 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000085943   ⟹   ENSRNOP00000070875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6128,985,453 - 128,989,812 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000134554   ⟹   ENSRNOP00000102240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl6128,239,552 - 128,258,301 (-)Ensembl
RefSeq Acc Id: NM_001011984   ⟹   NP_001011984
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,239,550 - 128,275,650 (-)NCBI
mRatBN7.26122,474,754 - 122,510,854 (-)NCBI
Rnor_6.06127,212,325 - 127,248,247 (-)NCBI
Rnor_5.06136,425,783 - 136,469,502 (-)NCBI
RGSC_v3.46127,609,500 - 127,645,492 (-)RGD
Celera6119,956,026 - 119,991,593 (-)RGD
Sequence:
RefSeq Acc Id: XM_006240464   ⟹   XP_006240526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,240,416 - 128,257,624 (-)NCBI
mRatBN7.26122,474,754 - 122,492,828 (-)NCBI
Rnor_6.06127,212,325 - 127,230,486 (-)NCBI
Rnor_5.06136,425,783 - 136,469,502 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112072   ⟹   XP_038968000
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,240,416 - 128,275,833 (-)NCBI
mRatBN7.26122,475,322 - 122,511,013 (-)NCBI
RefSeq Acc Id: XM_063261766   ⟹   XP_063117836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,240,416 - 128,275,833 (-)NCBI
RefSeq Acc Id: XR_593075
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86128,242,433 - 128,275,833 (-)NCBI
mRatBN7.26122,477,633 - 122,511,014 (-)NCBI
Rnor_6.06127,215,288 - 127,248,451 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001011984   ⟸   NM_001011984
- UniProtKB: Q5U2S6 (UniProtKB/Swiss-Prot),   A6JEM4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240526   ⟸   XM_006240464
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSRNOP00000071182   ⟸   ENSRNOT00000085517
RefSeq Acc Id: XP_038968000   ⟸   XM_039112072
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000070875   ⟸   ENSRNOT00000085943
RefSeq Acc Id: XP_063117836   ⟸   XM_063261766
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000102240   ⟸   ENSRNOT00000134554
Protein Domains
SOCS box   UIM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JZ15-F1-model_v2 AlphaFold A0A0G2JZ15 1-277 view protein structure
AF-Q5U2S6-F1-model_v2 AlphaFold Q5U2S6 1-634 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694790
Promoter ID:EPDNEW_R5315
Type:multiple initiation site
Name:Asb2_1
Description:ankyrin repeat and SOCS box-containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06127,248,260 - 127,248,320EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306414 AgrOrtholog
BioCyc Gene G2FUF-36419 BioCyc
Ensembl Genes ENSRNOG00000051619 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000057803 Ensembl
Ensembl Transcript ENSRNOT00000085517 ENTREZGENE
  ENSRNOT00000085517.2 UniProtKB/Swiss-Prot
  ENSRNOT00000134554 ENTREZGENE
Gene3D-CATH 1.25.40.20 UniProtKB/Swiss-Prot
  SOCS box UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7191983 IMAGE-MGC_LOAD
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot
  ASB2_SOCS UniProtKB/Swiss-Prot
  SOCS_box UniProtKB/Swiss-Prot
  SOCS_box-like_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:299266 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94662 IMAGE-MGC_LOAD
NCBI Gene 299266 ENTREZGENE
PANTHER ANK_REP_REGION DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED UniProtKB/Swiss-Prot
Pfam Ank_2 UniProtKB/Swiss-Prot
  Ank_3 UniProtKB/Swiss-Prot
  Ank_4 UniProtKB/Swiss-Prot
  SOCS_box UniProtKB/Swiss-Prot
PhenoGen Asb2 PhenoGen
PRINTS ANKYRIN UniProtKB/Swiss-Prot
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot
  ANK_REPEAT UniProtKB/Swiss-Prot
  SOCS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000051619 RatGTEx
  ENSRNOG00000057803 RatGTEx
SMART ANK UniProtKB/Swiss-Prot
  SOCS UniProtKB/Swiss-Prot
  SOCS_box UniProtKB/Swiss-Prot
Superfamily-SCOP SSF158235 UniProtKB/Swiss-Prot
  SSF48403 UniProtKB/Swiss-Prot
UniProt A0ABK0LPG4_RAT UniProtKB/TrEMBL
  A6JEM4 ENTREZGENE, UniProtKB/TrEMBL
  ASB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Asb2  ankyrin repeat and SOCS box-containing 2  LOC100909439  ankyrin repeat and SOCS box protein 2-like  Data merged from RGD:6503583 737654 PROVISIONAL
2012-07-05 LOC100909439  ankyrin repeat and SOCS box protein 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-25 Asb2  ankyrin repeat and SOCS box-containing 2  Asb2  ankyrin repeat and SOCS box-containing protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Asb2  ankyrin repeat and SOCS box-containing protein 2  Asb2_predicted  ankyrin repeat and SOCS box-containing protein 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Asb2_predicted  ankyrin repeat and SOCS box-containing protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED