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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pcdh20 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PCDH20 mRNA | CTD | PMID:32109520|PMID:33387578 | Pcdh20 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | 2,2',4,4',5-brominated diphenyl ether results in decreased expression of PCDH20 mRNA | CTD | PMID:26705709 | Pcdh20 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Pcdh20 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of PCDH20 mRNA | CTD | PMID:38648751 | Pcdh20 | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | Pcdh20 (Mus musculus) | 6480464 | tetrabromobisphenol A results in decreased expression of PCDH20 mRNA | CTD | PMID:25172293 | Pcdh20 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Pcdh20 (Mus musculus) | 6480464 | bisphenol S affects the methylation of PCDH20 gene | CTD | PMID:31683443 | Pcdh20 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of PCDH20 mRNA | CTD | PMID:24780913 | Pcdh20 | Rat | 8-Br-cAMP | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of PCDH20 mRNA | CTD | PMID:22079614 | Pcdh20 | Rat | all-trans-retinoic acid | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PCDH20 mRNA | CTD | PMID:21934132|PMID:23724009 | Pcdh20 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of PCDH20 mRNA | CTD | PMID:35163327 | Pcdh20 | Rat | antirheumatic drug | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of PCDH20 mRNA | CTD | PMID:24449571 | Pcdh20 | Rat | arsenous acid | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of PCDH20 mRNA | CTD | PMID:26705709 | Pcdh20 | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of PCDH20 mRNA | CTD | PMID:36841081 | Pcdh20 | Rat | benzo[a]pyrene | increases methylation | ISO | PCDH20 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of PCDH20 5' UTR; Benzo(a)pyrene results in increased methylation of more ... | CTD | PMID:27901495 | Pcdh20 | Rat | beta-lapachone | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of PCDH20 mRNA | CTD | PMID:38218311 | Pcdh20 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Pcdh20 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of PCDH20 mRNA | CTD | PMID:35716406 | Pcdh20 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of PCDH20 mRNA | CTD | PMID:26496021 | Pcdh20 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of PCDH20 mRNA | CTD | PMID:31129395 | Pcdh20 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PCDH20 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998 | Pcdh20 | Rat | bisphenol F | decreases expression | ISO | Pcdh20 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of PCDH20 mRNA | CTD | PMID:30951980 | Pcdh20 | Rat | buta-1,3-diene | increases expression | ISO | Pcdh20 (Mus musculus) | 6480464 | 1,3-butadiene results in increased expression of PCDH20 mRNA | CTD | PMID:29038090 | Pcdh20 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of PCDH20 mRNA | CTD | PMID:33453195 | Pcdh20 | Rat | CGP 52608 | multiple interactions | ISO | PCDH20 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PCDH20 gene] | CTD | PMID:28238834 | Pcdh20 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of PCDH20 mRNA | CTD | PMID:26577399 | Pcdh20 | Rat | cyclosporin A | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PCDH20 mRNA | CTD | PMID:20106945 | Pcdh20 | Rat | cytarabine | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of PCDH20 mRNA | CTD | PMID:21198554 | Pcdh20 | Rat | DDT | decreases expression | EXP | | 6480464 | DDT results in decreased expression of PCDH20 mRNA | CTD | PMID:30207508 | Pcdh20 | Rat | diarsenic trioxide | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of PCDH20 mRNA | CTD | PMID:26705709 | Pcdh20 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of PCDH20 mRNA | CTD | PMID:25152437 | Pcdh20 | Rat | dorsomorphin | multiple interactions | ISO | PCDH20 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Pcdh20 | Rat | doxorubicin | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PCDH20 mRNA | CTD | PMID:29803840 | Pcdh20 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PCDH20 mRNA | CTD | PMID:29391264 | Pcdh20 | Rat | entinostat | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | entinostat results in increased expression of PCDH20 mRNA | CTD | PMID:26272509 | Pcdh20 | Rat | entinostat | multiple interactions | ISO | PCDH20 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Pcdh20 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of PCDH20 mRNA | CTD | PMID:30307764 | Pcdh20 | Rat | folic acid | decreases expression | ISO | Pcdh20 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PCDH20 mRNA | CTD | PMID:25629700 | Pcdh20 | Rat | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of PCDH20 mRNA | CTD | PMID:24915197 | Pcdh20 | Rat | medroxyprogesterone acetate | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Medroxyprogesterone Acetate results in decreased expression of PCDH20 mRNA | CTD | PMID:20843944 | Pcdh20 | Rat | mercury dibromide | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of PCDH20 mRNA | CTD | PMID:26272509 | Pcdh20 | Rat | mercury dibromide | multiple interactions | ISO | PCDH20 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Pcdh20 | Rat | methylmercury chloride | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PCDH20 mRNA | CTD | PMID:23179753 | Pcdh20 | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of PCDH20 mRNA | CTD | PMID:24810058 | Pcdh20 | Rat | nickel atom | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Nickel results in decreased expression of PCDH20 mRNA | CTD | PMID:25583101 | Pcdh20 | Rat | niclosamide | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Niclosamide results in decreased expression of PCDH20 mRNA | CTD | PMID:36318118 | Pcdh20 | Rat | nitrofen | decreases expression | EXP | | 6480464 | nitrofen results in decreased expression of PCDH20 mRNA | CTD | PMID:26720608 | Pcdh20 | Rat | okadaic acid | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of PCDH20 mRNA | CTD | PMID:38832940 | Pcdh20 | Rat | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of PCDH20 mRNA | CTD | PMID:31397875 | Pcdh20 | Rat | ozone | multiple interactions | ISO | Pcdh20 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PCDH20 more ... | CTD | PMID:27106289 | Pcdh20 | Rat | panobinostat | multiple interactions | ISO | PCDH20 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Pcdh20 | Rat | panobinostat | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | panobinostat results in increased expression of PCDH20 mRNA | CTD | PMID:26272509 | Pcdh20 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of PCDH20 mRNA | CTD | PMID:33387578 | Pcdh20 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of PCDH20 mRNA | CTD | PMID:35163327 | Pcdh20 | Rat | phenylmercury acetate | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of PCDH20 mRNA | CTD | PMID:26272509 | Pcdh20 | Rat | phenylmercury acetate | multiple interactions | ISO | PCDH20 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Pcdh20 | Rat | pirinixic acid | multiple interactions | ISO | Pcdh20 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Pcdh20 | Rat | rotenone | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of PCDH20 mRNA | CTD | PMID:29955902 | Pcdh20 | Rat | SB 431542 | multiple interactions | ISO | PCDH20 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Pcdh20 | Rat | temozolomide | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of PCDH20 mRNA | CTD | PMID:31758290 | Pcdh20 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of PCDH20 mRNA | CTD | PMID:26496021 | Pcdh20 | Rat | trichostatin A | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PCDH20 mRNA | CTD | PMID:24935251 | Pcdh20 | Rat | triclosan | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of PCDH20 mRNA | CTD | PMID:30510588 | Pcdh20 | Rat | valproic acid | affects expression | ISO | Pcdh20 (Mus musculus) | 6480464 | Valproic Acid affects the expression of PCDH20 mRNA | CTD | PMID:17963808 | Pcdh20 | Rat | valproic acid | affects expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of PCDH20 mRNA | CTD | PMID:25979313 | Pcdh20 | Rat | valproic acid | increases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PCDH20 mRNA | CTD | PMID:19101580|PMID:23179753|PMID:24383497|PMID:24935251|PMID:25192806|PMID:26272509|PMID:28001369 | Pcdh20 | Rat | valproic acid | multiple interactions | ISO | PCDH20 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Pcdh20 | Rat | zoledronic acid | decreases expression | ISO | PCDH20 (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of PCDH20 mRNA | CTD | PMID:24714768 | |