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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Slc39a2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of SLC39A2 mRNA] | CTD | PMID:22206623 | Slc39a2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Slc39a2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of SLC39A2 mRNA | CTD | PMID:22206623 | Slc39a2 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of SLC39A2 mRNA; [Testosterone co-treated with more ... | CTD | PMID:26496021|PMID:32741896 | Slc39a2 | Rat | 17beta-estradiol 3-benzoate | decreases expression | EXP | | 6480464 | estradiol 3-benzoate results in decreased expression of SLC39A2 mRNA | CTD | PMID:32741896 | Slc39a2 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SLC39A2 mRNA | CTD | PMID:30851411 | Slc39a2 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Slc39a2 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of SLC39A2 mRNA | CTD | PMID:39298647 | Slc39a2 | Rat | aflatoxin B1 | increases methylation | ISO | SLC39A2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of SLC39A2 gene | CTD | PMID:27153756 | Slc39a2 | Rat | arsane | multiple interactions | ISO | SLC39A2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SLC39A2 more ... | CTD | PMID:32525701 | Slc39a2 | Rat | arsane | increases response to substance | ISO | SLC39A2 (Homo sapiens) | 6480464 | SLC39A2 gene SNP results in increased susceptibility to Arsenic | CTD | PMID:21947419 | Slc39a2 | Rat | arsenic atom | multiple interactions | ISO | SLC39A2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SLC39A2 more ... | CTD | PMID:32525701 | Slc39a2 | Rat | arsenic atom | increases response to substance | ISO | SLC39A2 (Homo sapiens) | 6480464 | SLC39A2 gene SNP results in increased susceptibility to Arsenic | CTD | PMID:21947419 | Slc39a2 | Rat | benzo[a]pyrene | affects methylation | ISO | SLC39A2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLC39A2 exon | CTD | PMID:27901495 | Slc39a2 | Rat | benzo[a]pyrene | decreases methylation | ISO | SLC39A2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SLC39A2 promoter | CTD | PMID:27901495 | Slc39a2 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of SLC39A2 mRNA | CTD | PMID:26496021 | Slc39a2 | Rat | bisphenol A | decreases expression | ISO | Slc39a2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SLC39A2 mRNA | CTD | PMID:32156529|PMID:38074096 | Slc39a2 | Rat | bisphenol A | increases expression | ISO | Slc39a2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of SLC39A2 mRNA | CTD | PMID:29165653 | Slc39a2 | Rat | bisphenol A | affects methylation | EXP | | 6480464 | bisphenol A affects the methylation of SLC39A2 promoter | CTD | PMID:27415467 | Slc39a2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SLC39A2 mRNA | CTD | PMID:25181051 | Slc39a2 | Rat | bisphenol F | decreases expression | ISO | Slc39a2 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of SLC39A2 mRNA | CTD | PMID:38685157 | Slc39a2 | Rat | calcitriol | decreases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of SLC39A2 mRNA | CTD | PMID:27107558 | Slc39a2 | Rat | carbamazepine | affects expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of SLC39A2 mRNA | CTD | PMID:25979313 | Slc39a2 | Rat | CGP 52608 | multiple interactions | ISO | SLC39A2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SLC39A2 gene] | CTD | PMID:28238834 | Slc39a2 | Rat | crocidolite asbestos | increases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Asbestos, Crocidolite results in increased expression of SLC39A2 mRNA | CTD | PMID:25351596 | Slc39a2 | Rat | cytarabine | decreases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of SLC39A2 mRNA | CTD | PMID:21198554 | Slc39a2 | Rat | dimethylarsinic acid | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Slc39a2 | Rat | ethanol | increases expression | ISO | Slc39a2 (Mus musculus) | 6480464 | Ethanol results in increased expression of SLC39A2 mRNA | CTD | PMID:19167417|PMID:30319688 | Slc39a2 | Rat | ethylparaben | increases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in increased expression of SLC39A2 mRNA | CTD | PMID:37690743 | Slc39a2 | Rat | folic acid | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of SLC39A2 mRNA] | CTD | PMID:22206623 | Slc39a2 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of SLC39A2 gene | CTD | PMID:22079235 | Slc39a2 | Rat | glutathione | multiple interactions | ISO | SLC39A2 (Homo sapiens) | 6480464 | [SLC39A2 protein co-treated with zinc chloride] results in increased abundance of Glutathione | CTD | PMID:18385089 | Slc39a2 | Rat | methylarsonic acid | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Slc39a2 | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | decreases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of SLC39A2 mRNA | CTD | PMID:18385089 | Slc39a2 | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | increases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A2 mRNA | CTD | PMID:12756304 | Slc39a2 | Rat | N-nitrosodiethylamine | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of SLC39A2 mRNA | CTD | PMID:24535843 | Slc39a2 | Rat | nitrofen | increases expression | EXP | | 6480464 | nitrofen results in increased expression of SLC39A2 mRNA | CTD | PMID:33484710 | Slc39a2 | Rat | ozone | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased more ... | CTD | PMID:34911549 | Slc39a2 | Rat | paracetamol | affects expression | ISO | Slc39a2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SLC39A2 mRNA | CTD | PMID:17562736 | Slc39a2 | Rat | phenobarbital | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of SLC39A2 mRNA | CTD | PMID:24535843 | Slc39a2 | Rat | rac-lactic acid | decreases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SLC39A2 mRNA | CTD | PMID:30851411 | Slc39a2 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SLC39A2 mRNA | CTD | PMID:28374803 | Slc39a2 | Rat | silicon dioxide | increases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of SLC39A2 mRNA | CTD | PMID:25895662 | Slc39a2 | Rat | silicon dioxide | increases expression | ISO | Slc39a2 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of SLC39A2 mRNA | CTD | PMID:29203145|PMID:29341224 | Slc39a2 | Rat | sodium arsenate | multiple interactions | ISO | SLC39A2 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of SLC39A2 more ... | CTD | PMID:32525701 | Slc39a2 | Rat | sodium arsenate | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Slc39a2 | Rat | sodium arsenite | multiple interactions | ISO | Slc39a2 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Slc39a2 | Rat | sulforaphane | multiple interactions | ISO | SLC39A2 (Homo sapiens) | 6480464 | sulforaphane promotes the reaction [SLC39A2 protein results in increased activity of NFE2L2 protein] | CTD | PMID:18385089 | Slc39a2 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [Testosterone co-treated with Estradiol] results in increased expression of SLC39A2 mRNA | CTD | PMID:32741896 | Slc39a2 | Rat | triclosan | increases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Triclosan results in increased expression of SLC39A2 mRNA | CTD | PMID:30510588 | Slc39a2 | Rat | valproic acid | increases methylation | ISO | SLC39A2 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of SLC39A2 gene | CTD | PMID:29154799 | Slc39a2 | Rat | vitamin E | increases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of SLC39A2 mRNA | CTD | PMID:19244175 | Slc39a2 | Rat | zinc atom | increases transport | ISO | SLC39A2 (Homo sapiens) | 6480464 | SLC39A2 protein results in increased transport of Zinc | CTD | PMID:18326752 | Slc39a2 | Rat | zinc atom | increases uptake | ISO | Slc39a2 (Mus musculus) | 6480464 | SLC39A2 protein results in increased uptake of Zinc | CTD | PMID:14525987|PMID:15322118 | Slc39a2 | Rat | zinc atom | increases expression | EXP | | 6480464 | Zinc results in increased expression of SLC39A2 mRNA | CTD | PMID:17028381 | Slc39a2 | Rat | zinc dichloride | multiple interactions | ISO | SLC39A2 (Homo sapiens) | 6480464 | [SLC39A2 protein co-treated with zinc chloride] results in increased abundance of Glutathione; zinc chloride promotes more ... | CTD | PMID:18385089 | Slc39a2 | Rat | zinc dichloride | increases expression | ISO | SLC39A2 (Homo sapiens) | 6480464 | zinc chloride results in increased expression of SLC39A2 mRNA | CTD | PMID:18385089 | Slc39a2 | Rat | zinc(0) | increases transport | ISO | SLC39A2 (Homo sapiens) | 6480464 | SLC39A2 protein results in increased transport of Zinc | CTD | PMID:18326752 | Slc39a2 | Rat | zinc(0) | increases expression | EXP | | 6480464 | Zinc results in increased expression of SLC39A2 mRNA | CTD | PMID:17028381 | Slc39a2 | Rat | zinc(0) | increases uptake | ISO | Slc39a2 (Mus musculus) | 6480464 | SLC39A2 protein results in increased uptake of Zinc | CTD | PMID:14525987|PMID:15322118 | |