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Gene: Zfand2b (zinc finger AN1-type containing 2B) Rattus norvegicus

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Symbol:

Zfand2b

Name:

zinc finger AN1-type containing 2B

RGD ID:

1306260

Description:

Predicted to enable K48-linked polyubiquitin modification-dependent protein binding activity and ubiquitin binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein targeting to ER; and regulation of insulin-like growth factor receptor signaling pathway. Predicted to act upstream of or within SRP-dependent cotranslational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be part of proteasome complex. Predicted to be active in endoplasmic reticulum. Orthologous to human ZFAND2B (zinc finger AN1-type containing 2B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

AIRAP-like protein; AN1-type zinc finger protein 2B; arsenite-inducible RNA-associated protein-like protein; LOC363253; MGC116391; RGD1306260; similar to RIKEN cDNA 1110060O18; zinc finger, AN1 type domain 2B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ZFAND2B (zinc finger AN1-type containing 2B)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Zfand2b (zinc finger, AN1 type domain 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Zfand2b (zinc finger AN1-type containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ZFAND2B (zinc finger AN1-type containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ZFAND2B (zinc finger AN1-type containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Zfand2b (zinc finger AN1-type containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ZFAND2B (zinc finger AN1-type containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ZFAND2B (zinc finger AN1-type containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Zfand2b (zinc finger AN1-type containing 2B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ZFAND2B (zinc finger AN1-type containing 2B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Zfand2b (zinc finger, AN1 type domain 2B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zfand2a (zinc finger, AN1-type domain 2A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12795	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CUZ1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER)
Caenorhabditis elegans (roundworm):	aip-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	84,114,170 - 84,117,115 (+)	NCBI		GRCr8
mRatBN7.2	9	76,665,466 - 76,668,447 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,665,546 - 76,668,445 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	85,110,107 - 85,113,024 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	90,238,998 - 90,241,915 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	88,625,211 - 88,628,128 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	82,370,887 - 82,373,843 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,370,924 - 82,373,839 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	82,140,181 - 82,143,104 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	74,451,779 - 74,454,698 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	74,598,760 - 74,601,680 (+)	NCBI
Celera	9	74,235,977 - 74,238,896 (+)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alacrima, achalasia, and impaired intellectual development syndrome (ISO)

cerebrotendinous xanthomatosis (ISO)

myofibrillar myopathy 1 (ISO)

Neurodevelopmental Disorders (ISO)

paroxysmal nonkinesigenic dyskinesia 1 (ISO)

polydactyly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

Aroclor 1254 (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (EXP)

caffeine (ISO)

cisplatin (ISO)

clofibrate (ISO)

copper(II) sulfate (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

gentamycin (EXP)

hydralazine (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

rotenone (ISO)

Soman (EXP)

sunitinib (ISO)

temozolomide (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteasome-mediated ubiquitin-dependent protein catabolic process (IBA,ISO)

protein targeting to ER (IBA,ISO)

regulation of insulin-like growth factor receptor signaling pathway (ISO)

SRP-dependent cotranslational protein targeting to membrane, translocation (ISO)

Cellular Component

cytoplasm (IBA)

endoplasmic reticulum (IBA,ISO)

endoplasmic reticulum membrane (IEA)

membrane (ISO)

proteasome complex (ISO)

Molecular Function

K48-linked polyubiquitin modification-dependent protein binding (ISO)

polyubiquitin modification-dependent protein binding (ISO)

protein binding (ISO)

ubiquitin binding (ISO)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334	PMID:18467495	PMID:24160817	PMID:26692333	PMID:26876100

Genomics

Comparative Map Data

Zfand2b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	84,114,170 - 84,117,115 (+)	NCBI		GRCr8
mRatBN7.2	9	76,665,466 - 76,668,447 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	76,665,546 - 76,668,445 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	85,110,107 - 85,113,024 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	90,238,998 - 90,241,915 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	88,625,211 - 88,628,128 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	82,370,887 - 82,373,843 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	82,370,924 - 82,373,839 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	82,140,181 - 82,143,104 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	74,451,779 - 74,454,698 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	74,598,760 - 74,601,680 (+)	NCBI
Celera	9	74,235,977 - 74,238,896 (+)	NCBI		Celera
Cytogenetic Map	9	q33	NCBI

ZFAND2B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	219,206,782 - 219,209,648 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	219,195,237 - 219,209,651 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	220,071,504 - 220,074,370 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	219,779,782 - 219,782,617 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	213,841,245 - 213,844,076 (+)	NCBI		Celera
Cytogenetic Map	2	q35	NCBI
HuRef	2	211,924,804 - 211,927,670 (+)	NCBI		HuRef
CHM1_1	2	220,077,341 - 220,080,208 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	219,691,549 - 219,694,414 (+)	NCBI		T2T-CHM13v2.0

Zfand2b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	75,145,290 - 75,148,270 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	75,145,290 - 75,148,273 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	75,168,646 - 75,171,626 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	75,168,646 - 75,171,629 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	75,165,220 - 75,168,200 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	75,051,893 - 75,054,772 (+)	NCBI		MGSCv36	mm8
Celera	1	75,659,513 - 75,662,491 (+)	NCBI		Celera
Cytogenetic Map	1	C4	NCBI
cM Map	1	38.61	NCBI

Zfand2b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	14,221,002 - 14,225,681 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	14,222,423 - 14,225,681 (-)	NCBI	ChiLan1.0	ChiLan1.0

ZFAND2B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	121,837,231 - 121,840,092 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	121,852,196 - 121,855,057 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	106,464,364 - 106,467,217 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	225,055,835 - 225,058,647 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	225,055,969 - 225,058,647 (+)	Ensembl	panpan1.1		panPan2

ZFAND2B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	25,757,454 - 25,760,366 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	25,757,669 - 25,760,132 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	26,583,410 - 26,586,262 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	25,772,748 - 25,775,601 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	25,772,743 - 25,775,362 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	25,677,178 - 25,680,023 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	25,612,271 - 25,615,129 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	25,633,120 - 25,635,966 (+)	NCBI		UU_Cfam_GSD_1.0

Zfand2b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	175,282,849 - 175,285,754 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936569	1,625,374 - 1,632,642 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936569	1,625,712 - 1,628,533 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ZFAND2B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	121,243,116 - 121,246,068 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	121,243,116 - 121,246,075 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	134,277,894 - 134,280,854 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ZFAND2B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	105,110,419 - 105,113,614 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	105,110,542 - 105,115,481 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	94,282,967 - 94,286,172 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Zfand2b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624823	5,805,147 - 5,808,485 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624823	5,805,147 - 5,808,500 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Zfand2b
3 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	194
Count of miRNA genes:	135
Interacting mature miRNAs:	152
Transcripts:	ENSRNOT00000025219
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	32535505	77535505	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	25268044	79271759	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1581517	Bp284	Blood pressure QTL 284			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	76650629	76771824	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
2303170	Bp332	Blood pressure QTL 332	3.73	0.027	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	55847841	77026453	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	42495343	79271511	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	36962359	77814038	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	23754144	83851531	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	40194188	85194188	Rat
2303180	Bp333	Blood pressure QTL 333		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	56627713	78595166	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	40194188	85194188	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	32535505	77535505	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001025745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245246	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083878	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083879	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC099215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000025219 ⟹ ENSRNOP00000025219

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	76,665,546 - 76,668,445 (+)	Ensembl
Rnor_6.0 Ensembl	9	82,370,924 - 82,373,839 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000117504 ⟹ ENSRNOP00000080649

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	76,665,882 - 76,668,445 (+)	Ensembl

RefSeq Acc Id:

NM_001025745 ⟹ NP_001020916

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,114,196 - 84,117,115 (+)	NCBI
mRatBN7.2	9	76,665,528 - 76,668,447 (+)	NCBI
Rnor_6.0	9	82,370,924 - 82,373,843 (+)	NCBI
Rnor_5.0	9	82,140,181 - 82,143,104 (+)	NCBI
RGSC_v3.4	9	74,451,779 - 74,454,698 (+)	RGD
Celera	9	74,235,977 - 74,238,896 (+)	RGD

Sequence:

show sequence

CGCGCGCCCTCCGAAGGAGGAGTAGGGGCCGCGAGCCGGCAGGCACCCAGGCTTCGGTAACCTG
TGCTGGGCGGGGGAGAGGAAGGGGCGGGGCGGGAGCCCCCGGAGTTGCTGTGTTGCGGACCCGG
CCCAGAACAGGAGTCCTTGGCACGCTCAGCTCCCGTTTCTTCCCAGCAGCAGGCCCGGCACGTC
CAGGCGATGGAGTTTCCGGACCTCGGGGCTCACTGTTCCGAGCCGAGCTGTCAGCGCTTGGATT
TTTTGCCACTCAAATGCGATGCCTGCTCCGGCATCTTCTGCGCAGACCATGTGGCCTACGCCCA
TCATCACTGTGGATCAGCTTACCAAAAGGATATCCAGGTACCTGTGTGCCCGCTCTGTAATGTG
CCTGTGCCGGTAGCCAGAGGGGAGCCTCCTGACCGGGCCGTAGGAGAGCATATTGACAGAGACT
GTCGCTCTGATCCGGCACAGCAAAAACGCAAGATCTTCACCAATAAGTGTGAACGATCTGGCTG
CCGGCAGCGAGAGATGATGAAACTGACTTGTGACCGCTGTGGCCGAAATTTCTGCATCAAGCAC
CGTCACCCACTGGACCATGATTGCTCTGGTGAAGGTCATCCGACCAGCCGGGCAGGGCTTGCTG
CTATCTCCAGAGCACAAGGTCTGGCTTCTACAAGCACTGTCCCCAGTCCAAGTCGGACCTTGCC
TTCGTCATCCTCCCCCAGCAGAGCCACACCCCAGCTTCCACCCAGGACAACCTCTCCAGTTATT
GCTTTGCAGAATGGCTTGAGTGAGGACGAGGCCCTGCAGCGTGCCCTGGAACTATCCCTTGCGG
AGGCTAAACCCCAGATCCCAAGTTCTCAAGAGGAAGAAGACCTGGCGTTAGCACAGGCGCTGTC
AGCCAGTGAGGCAGAGTACCAACAGCAGCAGGCGCAGAGCCGTAGCTTGAAGCCGTCCAACTGC
AGCCTGTGCTAGGGTCTGGGCTTGGGGAGGGAGGCTCACCCAAGGACTGTGGCCCTCACATCTC
CAGGGTACACAGGGAAAGGAAGCACAGAGAAGCCTGGATCACAGAGACAAGCAGGAGTAACGTG
GAGGATGTTCCATGGAGCCTGGAGAGGAAGGAAGCTTGTGCAGAAGAGGGTGGCTGAGAAGCGC
TCTCTGGTTGGGGCCTTGGTAGGTGCTAACCAGACTCAATCCCCACAGCCTCTTACATCGTATT
ACCCCACTTTTCCCCGGGGCTGCCACATGTAGCAGACAGGGAGAGGGCTGGGAAGAGTAAAGAC
TGGTGATTAGTAAGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006245245 ⟹ XP_006245307

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,114,170 - 84,117,115 (+)	NCBI
mRatBN7.2	9	76,665,466 - 76,668,447 (+)	NCBI
Rnor_6.0	9	82,370,887 - 82,373,843 (+)	NCBI
Rnor_5.0	9	82,140,181 - 82,143,104 (+)	NCBI

Sequence:

show sequence

CCGCGATGGACCCGCCCAACGTGATGACGTCAGTGCGCGCGCGCCCTCCGAAGGAGGAGTAGGG
GCCGCGAGCCGGCAGGCACCCAGGCTTCGCAGGCCCGGCACGTCCAGGCGATGGAGTTTCCGGA
CCTCGGGGCTCACTGTTCCGAGCCGAGCTGTCAGCGCTTGGATTTTTTGCCACTCAAATGCGAT
GCCTGCTCCGGCATCTTCTGCGCAGACCATGTGGCCTACGCCCATCATCACTGTGGATCAGCTT
ACCAAAAGGATATCCAGGTACCTGTGTGCCCGCTCTGTAATGTGCCTGTGCCGGTAGCCAGAGG
GGAGCCTCCTGACCGGGCCGTAGGAGAGCATATTGACAGAGACTGTCGCTCTGATCCGGCACAG
CAAAAACGCAAGATCTTCACCAATAAGTGTGAACGATCTGGCTGCCGGCAGCGAGAGATGATGA
AACTGACTTGTGACCGCTGTGGCCGAAATTTCTGCATCAAGCACCGTCACCCACTGGACCATGA
TTGCTCTGGTGAAGGTCATCCGACCAGCCGGGCAGGGCTTGCTGCTATCTCCAGAGCACAAGGT
CTGGCTTCTACAAGCACTGTCCCCAGTCCAAGTCGGACCTTGCCTTCGTCATCCTCCCCCAGCA
GAGCCACACCCCAGCTTCCACCCAGGACAACCTCTCCAGTTATTGCTTTGCAGAATGGCTTGAG
TGAGGACGAGGCCCTGCAGCGTGCCCTGGAACTATCCCTTGCGGAGGCTAAACCCCAGATCCCA
AGTTCTCAAGAGGAAGAAGACCTGGCGTTAGCACAGGCGCTGTCAGCCAGTGAGGCAGAGTACC
AACAGCAGCAGGGTACACAGGGAAAGGAAGCACAGAGAAGCCTGGATCACAGAGACAAGCAGGA
GTAACGTGGAGGATGTTCCATGGAGCCTGGAGAGGAAGGAAGCTTGTGCAGAAGAGGGTGGCTG
AGAAGCGCTCTCTGGTTGGGGCCTTGGTAGGTGCTAACCAGACTCAATCCCCACAGCCTCTTAC
ATCGTATTACCCCACTTTTCCCCGGGGCTGCCACATGTAGCAGACAGGGAGAGGGCTGGGAAGA
GTAAAGACTGGTGATTAGTAAGA

hide sequence

RefSeq Acc Id:

XM_006245246 ⟹ XP_006245308

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,114,195 - 84,117,115 (+)	NCBI
mRatBN7.2	9	76,665,514 - 76,668,447 (+)	NCBI
Rnor_6.0	9	82,370,920 - 82,373,843 (+)	NCBI
Rnor_5.0	9	82,140,181 - 82,143,104 (+)	NCBI

Sequence:

show sequence

TGCGCGCGCGCCCTCCGAAGGAGGAGTAGGGGCCGCGAGCCGGCAGGCACCCAGGCTTCGCAGC
AGGCCCGGCACGTCCAGGCGATGGAGTTTCCGGACCTCGGGGCTCACTGTTCCGAGCCGAGCTG
TCAGCGCTTGGATTTTTTGCCACTCAAATGCGATGCCTGCTCCGGCATCTTCTGCGCAGACCAT
GTGGCCTACGCCCATCATCACTGTGGATCAGCTTACCAAAAGGATATCCAGGTACCTGTGTGCC
CGCTCTGTAATGTGCCTGTGCCGGTAGCCAGAGGGGAGCCTCCTGACCGGGCCGTAGGAGAGCA
TATTGACAGAGACTGTCGCTCTGATCCGGCACAGCAAAAACGCAAGATCTTCACCAATAAGTGT
GAACGATCTGGCTGCCGGCAGCGAGAGATGATGAAACTGACTTGTGACCGCTGTGGCCGAAATT
TCTGCATCAAGCACCGTCACCCACTGGACCATGATTGCTCTGGTGAAGGTCATCCGACCAGCCG
GGCAGGGCTTGCTGCTATCTCCAGAGCACAAGGTCTGGCTTCTACAAGCACTGTCCCCAGTCCA
AGTCGGACCTTGCCTTCGTCATCCTCCCCCAGCAGAGCCACACCCCAGCTTCCACCCAGGACAA
CCTCTCCAGTTATTGCTTTGCAGAATGGCTTGAGTGAGGACGAGGCCCTGCAGCGTGCCCTGGA
ACTATCCCTTGCGGAGGCTAAACCCCAGATCCCAAGTTCTCAAGAGGAAGAAGACCTGGCGTTA
GCACAGGCGCTGTCAGCCAGTGAGGCAGAGTACCAACAGCAGCAGGGTACACAGGGAAAGGAAG
CACAGAGAAGCCTGGATCACAGAGACAAGCAGGAGTAACGTGGAGGATGTTCCATGGAGCCTGG
AGAGGAAGGAAGCTTGTGCAGAAGAGGGTGGCTGAGAAGCGCTCTCTGGTTGGGGCCTTGGTAG
GTGCTAACCAGACTCAATCCCCACAGCCTCTTACATCGTATTACCCCACTTTTCCCCGGGGCTG
CCACATGTAGCAGACAGGGAGAGGGCTGGGAAGAGTAAAGACTGGTGATTAGTAAGA

hide sequence

RefSeq Acc Id:

XM_039083878 ⟹ XP_038939806

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,114,187 - 84,117,115 (+)	NCBI
mRatBN7.2	9	76,665,529 - 76,668,447 (+)	NCBI

RefSeq Acc Id:

XM_039083879 ⟹ XP_038939807

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,114,170 - 84,117,115 (+)	NCBI
mRatBN7.2	9	76,665,466 - 76,668,447 (+)	NCBI

RefSeq Acc Id:

XM_063267396 ⟹ XP_063123466

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	84,114,192 - 84,117,115 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001020916	(Get FASTA)	NCBI Sequence Viewer
	XP_006245307	(Get FASTA)	NCBI Sequence Viewer
	XP_006245308	(Get FASTA)	NCBI Sequence Viewer
	XP_038939806	(Get FASTA)	NCBI Sequence Viewer
	XP_038939807	(Get FASTA)	NCBI Sequence Viewer
	XP_063123466	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH99215	(Get FASTA)	NCBI Sequence Viewer
	EDL75389	(Get FASTA)	NCBI Sequence Viewer
	EDL75390	(Get FASTA)	NCBI Sequence Viewer
	EDL75391	(Get FASTA)	NCBI Sequence Viewer
	EDL75392	(Get FASTA)	NCBI Sequence Viewer
	EDL75393	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000025219.5
	ENSRNOP00000080649.1
GenBank Protein	Q4KLG9	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001020916 ⟸ NM_001025745

- UniProtKB:

Q4KLG9 (UniProtKB/Swiss-Prot), A6JVY1 (UniProtKB/TrEMBL), A6JVY4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEFPDLGAHCSEPSCQRLDFLPLKCDACSGIFCADHVAYAHHHCGSAYQKDIQVPVCPLCNVPV
PVARGEPPDRAVGEHIDRDCRSDPAQQKRKIFTNKCERSGCRQREMMKLTCDRCGRNFCIKHRH
PLDHDCSGEGHPTSRAGLAAISRAQGLASTSTVPSPSRTLPSSSSPSRATPQLPPRTTSPVIAL
QNGLSEDEALQRALELSLAEAKPQIPSSQEEEDLALAQALSASEAEYQQQQAQSRSLKPSNCSL
C

hide sequence

RefSeq Acc Id:	XP_006245307 ⟸ XM_006245245
- Peptide Label:	isoform X1
- UniProtKB:	A6JVY4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEFPDLGAHCSEPSCQRLDFLPLKCDACSGIFCADHVAYAHHHCGSAYQKDIQVPVCPLCNVPV PVARGEPPDRAVGEHIDRDCRSDPAQQKRKIFTNKCERSGCRQREMMKLTCDRCGRNFCIKHRH PLDHDCSGEGHPTSRAGLAAISRAQGLASTSTVPSPSRTLPSSSSPSRATPQLPPRTTSPVIAL QNGLSEDEALQRALELSLAEAKPQIPSSQEEEDLALAQALSASEAEYQQQQGTQGKEAQRSLDH RDKQE hide sequence

RefSeq Acc Id:	XP_006245308 ⟸ XM_006245246
- Peptide Label:	isoform X1
- UniProtKB:	A6JVY4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEFPDLGAHCSEPSCQRLDFLPLKCDACSGIFCADHVAYAHHHCGSAYQKDIQVPVCPLCNVPV PVARGEPPDRAVGEHIDRDCRSDPAQQKRKIFTNKCERSGCRQREMMKLTCDRCGRNFCIKHRH PLDHDCSGEGHPTSRAGLAAISRAQGLASTSTVPSPSRTLPSSSSPSRATPQLPPRTTSPVIAL QNGLSEDEALQRALELSLAEAKPQIPSSQEEEDLALAQALSASEAEYQQQQGTQGKEAQRSLDH RDKQE hide sequence

Ensembl Acc Id:

ENSRNOP00000025219 ⟸ ENSRNOT00000025219

RefSeq Acc Id:	XP_038939807 ⟸ XM_039083879
- Peptide Label:	isoform X2
- UniProtKB:	Q4KLG9 (UniProtKB/Swiss-Prot), A6JVY1 (UniProtKB/TrEMBL), A6JVY4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038939806 ⟸ XM_039083878
- Peptide Label:	isoform X1
- UniProtKB:	A6JVY4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000080649 ⟸ ENSRNOT00000117504

RefSeq Acc Id:	XP_063123466 ⟸ XM_063267396
- Peptide Label:	isoform X2
- UniProtKB:	Q4KLG9 (UniProtKB/Swiss-Prot), A6JVY1 (UniProtKB/TrEMBL), A6JVY4 (UniProtKB/TrEMBL)

Protein Domains

AN1-type UIM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4KLG9-F1-model_v2	AlphaFold	Q4KLG9	1-257	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696768

Promoter ID:

EPDNEW_R7292

Type:

initiation region

Name:

Zfand2b_1

Description:

zinc finger AN1-type containing 2B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	82,370,918 - 82,370,978	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306260	AgrOrtholog
BioCyc Gene	G2FUF-27094	BioCyc
Ensembl Genes	ENSRNOG00000018639	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000025219.6	UniProtKB/Swiss-Prot
	ENSRNOT00000117504.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.1110.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7384656	IMAGE-MGC_LOAD
InterPro	AN1-like_Znf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	UIM_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_AN1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:363253	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:116391	IMAGE-MGC_LOAD
NCBI Gene	363253	ENTREZGENE
PANTHER	AN1-TYPE ZINC FINGER PROTEIN 2B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	zf-AN1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Zfand2b	PhenoGen
PROSITE	UIM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_AN1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000018639	RatGTEx
SMART	UIM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZnF_AN1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF118310	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZQ31_RAT	UniProtKB/TrEMBL
	A6JVY1	ENTREZGENE, UniProtKB/TrEMBL
	A6JVY4	ENTREZGENE, UniProtKB/TrEMBL
	A6JVY5_RAT	UniProtKB/TrEMBL
	Q4KLG9	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-17	Zfand2b	zinc finger AN1-type containing 2B	Zfand2b	zinc finger, AN1 type domain 2B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Zfand2b	zinc finger, AN1 type domain 2B	RGD1306260	similar to RIKEN cDNA 1110060O18	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1306260	similar to RIKEN cDNA 1110060O18	RGD1306260_predicted	similar to RIKEN cDNA 1110060O18 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1306260_predicted	similar to RIKEN cDNA 1110060O18 (predicted)	LOC363253_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC363253_predicted	similar to RIKEN cDNA 1110060O18 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar