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Gene: Sass6 (SAS-6 centriolar assembly protein) Rattus norvegicus

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Symbol:

Sass6

Name:

SAS-6 centriolar assembly protein

RGD ID:

1306255

Description:

Predicted to be involved in centriole replication; positive regulation of cell cycle process; and spermatogenesis. Predicted to be located in cytoplasm and deuterosome. Predicted to be part of procentriole replication complex. Predicted to be active in centriole and centrosome. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 14. Orthologous to human SASS6 (SAS-6 centriolar assembly protein); INTERACTS WITH 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC102555636; LOC310807; RGD1306255; similar to 2810453L12Rik protein; spindle assembly 6 homolog; spindle assembly 6 homolog (C. elegans); spindle assembly abnormal protein 6 homolog; uncharacterized LOC102555636

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SASS6 (SAS-6 centriolar assembly protein)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Sass6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sass6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SASS6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SASS6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sass6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SASS6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SASS6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sass6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Sass6 (SAS-6 centriolar assembly protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DEFB103B (defensin beta 103B)	HGNC	OMA
Homo sapiens (human):	DEFB103A (defensin beta 103A)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Sass6 (SAS-6 centriolar assembly protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SASS6 (SAS-6 centriolar assembly protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sass6 (SAS-6 centriolar assembly protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Sas-6	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	Sas-6	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	sass6.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sass6.2	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	sass6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector)
Xenopus tropicalis (tropical clawed frog):	sass6	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	207,231,896 - 207,263,840 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	207,231,333 - 207,263,851 (+)	Ensembl				GRCr8
mRatBN7.2	2	204,546,660 - 204,578,930 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	204,546,660 - 204,578,927 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	212,203,668 - 212,227,945 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	210,112,851 - 210,136,947 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	204,929,924 - 204,954,021 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	219,626,851 - 219,660,975 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	219,628,695 - 219,652,968 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	237,557,441 - 237,588,679 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	212,825,474 - 212,849,747 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	197,038,483 - 197,062,724 (+)	NCBI		Celera
RGSC_v3.1	2	212,788,526 - 212,818,898 (+)	NCBI
Cytogenetic Map	2	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

primary autosomal recessive microcephaly 14 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

CU-O LINKAGE (ISO)

DDE (ISO)

decabromodiphenyl ether (EXP)

diazinon (EXP)

dicrotophos (ISO)

diethylstilbestrol (ISO)

dioxygen (ISO)

folic acid (ISO)

formaldehyde (ISO)

GSK-J4 (ISO)

inulin (ISO)

leflunomide (ISO)

methimazole (EXP)

mono(2-ethylhexyl) phthalate (ISO)

monobenzyl phthalate (ISO)

Monobutylphthalate (ISO)

monoethyl phthalate (ISO)

okadaic acid (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

quercetin (ISO)

sodium dodecyl sulfate (ISO)

sulfadimethoxine (EXP)

testosterone (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

tributylstannane (EXP)

triphenyl phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

centriole replication (IBA,ISO)

centrosome duplication (ISO)

positive regulation of centriole replication (ISO)

positive regulation of G1/S transition of mitotic cell cycle (ISO)

spermatogenesis (IBA)

Cellular Component

centriole (IBA,IEA,ISO)

centrosome (IBA,IEA,ISO)

cytoplasm (ISO)

deuterosome (ISO)

procentriole replication complex (ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15665853	PMID:16244668	PMID:17681131	PMID:21399614	PMID:22020124	PMID:22349705	PMID:24075808	PMID:24107630	PMID:24421332

Genomics

Comparative Map Data

Sass6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	207,231,896 - 207,263,840 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	207,231,333 - 207,263,851 (+)	Ensembl				GRCr8
mRatBN7.2	2	204,546,660 - 204,578,930 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	204,546,660 - 204,578,927 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	212,203,668 - 212,227,945 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	210,112,851 - 210,136,947 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	204,929,924 - 204,954,021 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	219,626,851 - 219,660,975 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	219,628,695 - 219,652,968 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	237,557,441 - 237,588,679 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	212,825,474 - 212,849,747 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	197,038,483 - 197,062,724 (+)	NCBI		Celera
RGSC_v3.1	2	212,788,526 - 212,818,898 (+)	NCBI
Cytogenetic Map	2	q42	NCBI

SASS6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	100,083,570 - 100,132,930 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	100,083,563 - 100,132,955 (-)	Ensembl			hg38	GRCh38
GRCh37	1	100,549,126 - 100,598,486 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	100,321,688 - 100,371,099 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	98,805,981 - 98,855,389 (-)	NCBI		Celera
Cytogenetic Map	1	p21.2	NCBI
HuRef	1	98,671,854 - 98,721,264 (-)	NCBI		HuRef
CHM1_1	1	100,665,439 - 100,714,865 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	99,931,689 - 99,981,045 (-)	NCBI		T2T-CHM13v2.0

Sass6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	116,388,577 - 116,424,816 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	116,388,631 - 116,424,653 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	116,594,938 - 116,630,986 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	116,594,982 - 116,631,004 (+)	Ensembl			mm10	GRCm38
MGSCv37	3	116,297,926 - 116,333,902 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	3	116,587,012 - 116,621,151 (+)	NCBI		MGSCv36	mm8
Celera	3	123,022,163 - 123,057,932 (+)	NCBI		Celera
Cytogenetic Map	3	G1	NCBI
cM Map	3	50.4	NCBI

Sass6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955435	4,832,284 - 4,879,010 (-)	Ensembl
ChiLan1.0	NW_004955435	4,832,284 - 4,876,077 (-)	NCBI	ChiLan1.0	ChiLan1.0

SASS6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	126,894,888 - 126,944,006 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	126,052,966 - 126,102,037 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	102,741,808 - 102,790,850 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	101,457,559 - 101,506,348 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	101,459,348 - 101,506,072 (-)	Ensembl			panPan2	panpan1.1

SASS6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	49,859,597 - 49,902,407 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	49,859,182 - 49,900,757 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	52,532,393 - 52,575,607 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	50,209,089 - 50,252,236 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	50,209,170 - 50,252,236 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	49,900,764 - 49,943,907 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	49,879,765 - 49,922,915 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	50,311,435 - 50,354,653 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Sass6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	110,442,855 - 110,484,777 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936748	249,934 - 289,787 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936748	249,216 - 290,062 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SASS6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	117,985,759 - 118,050,040 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	117,985,599 - 118,049,129 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SASS6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	33,205,538 - 33,254,292 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	33,205,742 - 33,257,170 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666038	24,802,894 - 24,852,018 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sass6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624857	2,882,133 - 2,930,508 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624857	2,872,335 - 2,930,481 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Sass6
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	43,094,222 - 43,125,926 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Sass6
285 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	40
Count of miRNA genes:	38
Interacting mature miRNAs:	39
Transcripts:	ENSRNOT00000067324
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	163997722	225110681	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	169358774	214358774	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	204795005	249795005	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	124537199	209621565	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	191709311	217961898	Rat
1302789	Stl26	Serum triglyceride level QTL 26	3.1	0.0035	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	206613059	226891081	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	196140964	251540988	Rat
61467	Bp14	Blood pressure QTL 14	2.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170652929	215652929	Rat
70175	BpQTLCluster3	Blood pressure QTL cluster 3	4.128		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	2	205135267	250135267	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	220931218	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	188565047	233565047	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	192287802	229609668	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	184856304	229856304	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	184856304	229856304	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	191709311	217961898	Rat
1357991	Ael2	Aortic elastin QTL 2	4.2	0.000071	aorta elastin amount (VT:0003905)	aortic elastin	2	169227906	214227906	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	192287802	221089121	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	184856304	229856304	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	192287802	237287802	Rat
1578671	Bmd10	Bone mineral density QTL 10	5.4		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	175931416	220931416	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	182024327	227024327	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	159440760	228950743	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	184482291	229482291	Rat
631501	Bp101	Blood pressure QTL 101	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	205135267	250135267	Rat
1598813	Memor9	Memory QTL 9	2.7		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	2	202029709	236904960	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
2298479	Eau5	Experimental allergic uveoretinitis QTL 5		0.0021	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	2	205135267	225627153	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	145306936	212705578	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	186850607	231850607	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	192287802	237287802	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	223841096	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	182635347	227635347	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	220008837	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	184856304	229856304	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	203664411	248664411	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	165453811	210453811	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	163253030	208253030	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat

Markers in Region

D2Got135

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	204,574,182 - 204,574,424 (+)	MAPPER	mRatBN7.2
mRatBN7.2	2	204,574,182 - 204,574,424 (-)	MAPPER	mRatBN7.2
Rnor_6.0	2	219,656,215 - 219,656,456	NCBI	Rnor6.0
Rnor_6.0	1	69,825,734 - 69,825,975	NCBI	Rnor6.0
Rnor_5.0	2	237,561,960 - 237,562,201	UniSTS	Rnor5.0
Rnor_5.0	1	71,222,654 - 71,222,895	UniSTS	Rnor5.0
RGSC_v3.4	2	212,852,994 - 212,853,235	UniSTS	RGSC3.4
RGSC_v3.4	2	212,852,993 - 212,853,235	RGD	RGSC3.4
Celera	2	197,065,971 - 197,066,224	UniSTS
RGSC_v3.1	2	212,815,748 - 212,815,989	RGD
RH 3.4 Map	2	1479.9	UniSTS
RH 3.4 Map	2	1479.9	RGD
RH 2.0 Map	2	1044.8	RGD
Cytogenetic Map	2	q41	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	67	165	91	90	59	92	59	6	354	191	11	144	80	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001415058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233228	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039102429	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281937	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119448	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000020757 ⟹ ENSRNOP00000020757

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	207,232,045 - 207,263,851 (+)	Ensembl
mRatBN7.2 Ensembl	2	204,547,133 - 204,578,927 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000067324 ⟹ ENSRNOP00000063437

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	207,231,896 - 207,263,836 (+)	Ensembl
mRatBN7.2 Ensembl	2	204,546,660 - 204,578,100 (+)	Ensembl
Rnor_6.0 Ensembl	2	219,628,695 - 219,652,968 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112539 ⟹ ENSRNOP00000097084

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	207,231,896 - 207,263,836 (+)	Ensembl
mRatBN7.2 Ensembl	2	204,546,904 - 204,578,927 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000152529 ⟹ ENSRNOP00000099745

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	207,231,333 - 207,262,048 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000164886 ⟹ ENSRNOP00000103659

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	207,231,890 - 207,263,851 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000169989 ⟹ ENSRNOP00000109160

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	207,231,846 - 207,263,851 (+)	Ensembl

RefSeq Acc Id:

NM_001415058 ⟹ NP_001401987

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	207,231,896 - 207,263,837 (+)	NCBI
mRatBN7.2	2	204,546,984 - 204,578,930 (+)	NCBI

RefSeq Acc Id:

XM_006233228 ⟹ XP_006233290

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	207,231,932 - 207,263,840 (+)	NCBI
mRatBN7.2	2	204,546,660 - 204,578,930 (+)	NCBI
Rnor_6.0	2	219,626,851 - 219,660,975 (+)	NCBI
Rnor_5.0	2	237,557,441 - 237,588,679 (-)	NCBI

Sequence:

show sequence

ACTGAGCTAAATCCCCAACCCCTGCATACTTATTCTTTAATTTTAAAATGTTGCCCATTTAAAC
TGATTTTAGAATGCGTATTTATCTAAAGCTGTTTAAACGTAGGGAAATGCTGGGCGTGGTGGAC
CATGCTTTGAATATCAGCACTGCGGAGGAAAGGCAGACAGAGCTTTTGAGCCAAAGACCAGCCA
GGGTAACCCTCAGGCCCTGTCTCAATAAAGACAGAAATCAAATACAGGAGAACGTATGACAGGA
ACAACGAGGCATGGTACTTTAACAATTTAGAATGGGTCATATTCCCTGGCTTTGCAACTTTTCA
AAAATGCTAGTTACTGTCTTTCAAGTTATATACATTTAATTATAGGCAACGGGTGGAAAGCAAG
AAAAACCAGTATTGGCATGCCTACCTTACAGACCCTATCAACACATGCACATGATGGCCCAATT
ATTAAAACCAGAGGCCAGTGGTTATGATTCTCAGTTCTTTCTATTAGCTGCTAACTCTATGTCT
ATGACCCAACACTAACACTCACTGCCTCATGTGAATAATAGTATATACTCCCTAAGTATAGACT
TACTATATCCCTATTAAATAGAATAATAGCATGATTTATTTCCTAAGGTTTGTGAAAATTGAAT
TTTTAAAAGAAAAGTAACAATGTTTAGTGCTAGCCATACAGCAAAAGCTGACCAAGTATTTACT
CTTATTTTTTCTCAATTATTTATTTCAATTTATTTCAGAATGTTCATGATGTTATGCACACTGA
ATTTTAGGGAAAGTTAAGAAATTCTCAGTATTAAGAATAACCTATATTATTTCTTCTTCACGTA
CAGATTTTAAAATTTAATTTCCAGTGTGATTGTTTGGTGTTGACCAGCTAGTTGGGAGGCTGAG
GCAGGAGAATTCCTGAGACCAGGTATTCAAGACCAACATGAGAAATTCAGTGAGATCACCATCT
CAAAGACAAACAGGAAAATTGTCTTTCAAGGGAAATAGTAATCTATTCTAGCTTGCAAAGCTAA
ATCGCAGAAAACACACACACACAGGCGCGAGCACACGCACGCGCGCGCGCGCACACACACACAC
ACAAAGCATTCTTAATTTAGAAACTGTTATAAAGATGTTTTCTTTTTTGGTGTAGAGGGTGGTG
AGACTTCCTGTGACCTGCGGATTAGTAATTTTCCTGTTCTCTATCCATTTGAAGCCCCTGACAT
TTTTGCACTTAGAACCAAAATGTCTTATGACATTAATGTCTGCTGGGGTTGGAAGACAAAAATG
CACTCTGCTTTCAACTTTTAATGTTAGTTACTTTAGGTTAATTCTTCTTCCCCCTCCCAGAATA
ATAATTACAAGCTCATAAGGTGTTTCCTGGAGAGTTAAGTCTAAACAAAAAACATTTTTTTTCT
AAGTTTCTTCCTCATGCACTCAAGTGGTTATCGTTCAGAAAACAATAAGTATAATTAGAACCCA
GTTAGTAAAGTCTGGTGATTTCAAACACTATTCTGTAAAGATAATCACTTCCCATGAGGATGGG
CGACTGATGGAAGGATGAGCACAAAGATCTCTATGATAGCACAGAGGATCATCTCTTGGCTATT
CTTAGCACTTAGTCCAAGAAAGCAATGTTCCTCAGGAGCTCATCGTGGCTCCAAGCGGTGGTCA
GAACTGCATTTACTTAAGTAAAGGCTGGAGAATCCATGGGGCAGAAGCAGAAACCTGTCAAAGG
GGGTGAGGATGGGTTCCAGCACCCACAGACCAGCAACTCAGTTCCGACTCTCAGGAAGGTAGGG
CGATACCAGACCTCCGCCGATCCAGCGTGTTCACCACAGAACCTTTTCCCCGCGGCCACCACCA
TCCTGCAGAAGCGCTTCTTCTTTTCCACAAAGTAGTTGCATCTACCGTCAGTTGGAAAACCGAT
CGCGGGCGTTGTCGGAGCAGGAGCCTCCATCACGCTGGGTCCTTTTGGCCTGGCTCAACCCAAA
GTTGTCAATTCCCTCTGGTCCCGCTTCCCTTAACAAACGTGGCCGCCTGAAGGGGGTGGGACCA
CGGAAATTACGCATCACCCTGACTTATTCGTTCCCTCAACCGGAAGAAAGTGATGGTGGCTGAA
GAGGTCCAAACCTCCTTCGTTCCCTCTGTTTATCGTTCCCCTCCTCCGCCGGAGCTGAGCGCCA
AACTCAAACTTAGTCTGGAGCAGTACTTCTTTTAAGCTGGTACCGCGGGCCAGGCCTACTGGGC
TTTTTCACTCACGGGTCGGGGCAGCGGTCCGACATGAGTCAAGTTCTGTTCCAGCAACTTGTTC
CCTTGCTAGTGAAATGCAAAGACTGCGAGGAGAGGAGAGGGAGCGTTAGAGTGAGCATTGAACT
ACAGTCACTGTCTAATCCAGTACACAGAAAGGATCTAGTCATCCGTCTGACTGATGATACAGAT
CCATTTTTTCTGTATAACCTTGTTATATCCGAGGAAGACTTTCAAAGTTTAAAATTGCAGCAAG
GTCTCCTGGTGGACTTCTTATCTTTTCCACAGAAGTTTATAGACCTCCTTCAGCAATGTATGCA
GGAGCATGTGAAAGAGACTCCAAGGTTTCTGCTGCAGCTCACGTCTTCAGCTGCTCTTTTGGAT
AACTCGCCGGTGTTTTTAAATGTAGTGGAGACAAATCCTTTTAAGCATCTTATTCACCTGTCAC
TAAAGCTTTTACCTGGAAATGATGTAGAAATAAAGAAATTTCTAGCAGGATGCTTGAAATGTAG
CAAGGAAGAAAAATTATCACTGACTAAATCACTAGATGATGTTACCAGGCAACTGCACATTACA
CAAGAGACACTCTCGGAAAAGATGCAGGAACTAGATAAGTTGCGGAGTGAGTGGGCCTCGCACA
CAGCAGCGCTGACCAATAAGCACTCCCAGGAGTTAACAAACGAGAAGGAGAAAGCCTTGCAGAC
ACAAGTTCAGTACCAACAGCAGCATGAACAACAGAAAAAGGATCTGGAAGCCCTCCATCAACGA
AATATCCACCAGCTACAAAACAGATTGTCTGAGTTAGAGGCAGCTAATAAAGAGCTCACCGAGA
GGAAGTATAAAGGAGACTCCACTGTCAGAGAACTAAAAGCGAAGCTTGCTGGTGTGGAAGAGGA
GCTGCAGCGGACCAAGCAAGAGGTCCTTTCTCTGAGAAGAGAGAATTGTACTCTGGATACTGAA
TGCCACGAGAAAGAAAAGCATATTAACCAGCTACAAACAAAAGTGGCCGTTTTAGAACAGGAGA
TCAAGGATAAAGACCAGCTTGTTCTGAGAACAAAAGAAGCATTCGATACAATCCAAGAGCAAAA
GGTGGCTTTAGAAGAAAATGGTGAGAAAAATCAGATACAATTGGGAAAACTTGAAGCTACAATA
AAATCATTATCAGCAGAACTTCTAAAGGCGAATGAGATTATCAAGAAGTTACAAGGAGATCTTA
AAACTCTGATGGGTAAATTGAAACTGAAGAATACAGTTACTATTCAGCAAGAAAAGCTATTGGC
TGAGAAAGAAGAAATGCTACAAAAGGAGCGAAAGGAATCACAGGATGCTGGGCAGTCTCTTCGG
GCCAAAGAGCAAGAGGTATGCAGATTACAAGAACAATTAGAAACTACAGTTCAGAAACTTGAAG
AAAGTAAACAACTTTTGAAAAATAATGAAAAATTAATCACATGGCTAAACAAAGAACTAAATGA
AAACCAGCTGGGAAGAAAGCAAGACACACTGGGGGCCTCTGCCACCCCACCCACACATTCTGCT
AGCAACACCGTCAGAAGTGGGCTTTCTCCCAGCCTGAATGTGGTTGATAGTAGACTAAATTACC
CAAGCTGTGGAATTGGCTATCCTGTCTCGTCTGCGTTCACATTCCAGAATGCTTTTCCTCATGC
AGTAGTTGCCAAAAACACCAGCCATCCAGTCTCTGGACCAAAGGTGCAGTTCAGCTTGCAGCTG
ACAAAGCAAAGCACGTCGTCGGGAGATGGGCAGCCGGGAGCGGCTGTTAACAGGTCTGCTTCAG
CTGACAAGGAGAAACCATCAGAAAGATGGCATGCTGGGAGCGCTGCAGACATCTTCCAAACCCA
CAGTCCTGCCCCCATCTTCATCGTATTTTCCTGGGCCATTACCAAGTAGTTAATCCGACACCTT
TCACTGCTTACTGACAGTTTAGAAACTCAAGTGACTTAACAGACCATTAATAACACCAGTCTTT
TCTTGTTCCTGTTAGGTCATTTGTATCCTTTATAATAGTGCTGCCATTGACAAACTTAGGACAT
TGATAAGGACTCTGAGTAAATGGTATTTTTTTCTGTGAGCACAACAGAATATTTAAAAAAAAAA
AAAGTCACTGAATTGTATCGGATTTTTACCAGTTGGTCTGAATAGGGACACTAAATCAAAGATA
AGCCTGCAGAGAATAGTAGTAACAAGCTGAAGAAGACTTGTGATTCATACTATCATTTCTGTTA
TTAAAAAATTATTAATTTGCCACCTGAGAGTTGGGAGGGCTTCCACCTGTGATCATTGGTCTTT
ACACTGAGTTAGTATACTACTTTCAAAGGGTTTTTTTGTTTGTTTTTCTTTGAGATAGGGTCTA
TTATGTAGTTCAGGCTGCAGAACATGCCATGTATGTAGACTAGGCTGGTCTGAAATCCAGATCC
GCCTGCCTCTGTCTCCCAACACCTGGTATGTACTACTGAGCCTGATTTACACAATGTATTTTGG
TTTATTCTTTCTCCTCTCAGGTGCTCTCCAATTTCCTACCCACCCAATTCCATATTTTCTCCCT
TAAAAAGAAAATTAAAATAACCAACCAGTAAGATAAAAATATCAAACCAAAACCAATGGATTTG
ACCTTGTGTTAGTCAACAACTCCTGGGTGTGGGTGTTTGGAATTTGGCTGATATACTCGATAGT
CTTAAGCACTTTGAGTGAAAGTTAAGTATTCGTAGTGAGCGGATTATTTTCTCTGACATGTTTG
ATCTATGAAATGATTTTATATAAAAATTGGGCAGTATATTTACATGACTGAAATGCTTTAGTCG
TCTGGGCTGAGCATAGTTGATTTTGACACTTCCATACAAGATCATCAGTGGAATAGCACCATAA
AAGTTTTTATAATATACTTTTACAATATTTGTGCTCAGTGTTAATAAAGCAGGCAAGTTAACTA
TTGGAAGTTACAACTTTCTCATTATTAAAAACTTCCAAGAATTATTCCTTGGAAATTAAGTAGT
TTCAAAAAACAAAACAAAACCAAAACTAACACTCAGTAATCTTAGAGGTCTAGTTTTGTTTTCT
TGTTGATAACACCCCAAATCTTATCTGTAAAATGTAACAATCATGTGATATTTTCAAAGTTTCA
AGAGGCTGGCGAGATGGCTCGGTTGTTGATTAGCACTAAATATCTTTCAGAGGACATGGGGGTT
CTAGTCCCAGAACCCACATGGCAGCTCATGATTGTATGTCACCCACAGTGCATCAGGCATGTGG
TTTCTAAATATACACTGTTGAAGACATTTTGAGACTGAGACATATTAACTATGAGGGCTACAGG
AGAACAGGGATCTTTAGTCTCACTTTCAGGATGATAGCATCTGCCATCTATCTTCAACAAGGAA
GGGCTGAAGTAGAAGTTCAGTGATGTAAGGCTATTGGTACAACTACTTGAGAGCACTTATTCTG
GAAAGAAGCCTCTTGCCAGCACAGGACTGTTGTAAATACTGTAAAGTAAGCGTCAGTGCTTGCG
GCCGGCTTTGGGAAGGGATTAAGACGTATCTATTAGCTTTGTGAAGAGATACCCTCCCCTTACT
ATTTATAAACATTTCCAAGATAGGCTGTTGGTGAGCTGTCTGTGCTAAGTGTCCACCACACGGA
TAGTGCTAACTCTCTGCTCTACCTCTCAGCTTTTGTTTGAAATTGTTTTGTATAACTGTACATG
TGTTAATAATCAAAATGTTGTTCTTTGCTATTTCTGAAAACTGTGACCTTTGTTAATAAAGCAC
TGAAACCTCAGAATTTTATATATCA

hide sequence

RefSeq Acc Id:

XM_039102429 ⟹ XP_038958357

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	207,231,932 - 207,255,591 (+)	NCBI
mRatBN7.2	2	204,546,917 - 204,570,606 (+)	NCBI

RefSeq Acc Id:

XM_063281937 ⟹ XP_063138007

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	207,231,932 - 207,263,840 (+)	NCBI

RefSeq Acc Id:

XM_063281938 ⟹ XP_063138008

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	207,231,932 - 207,263,840 (+)	NCBI

RefSeq Acc Id:

XM_063281939 ⟹ XP_063138009

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	207,231,932 - 207,255,594 (+)	NCBI

RefSeq Acc Id:

XM_063281940 ⟹ XP_063138010

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	207,245,022 - 207,263,840 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001401987	(Get FASTA)	NCBI Sequence Viewer
	XP_006233290	(Get FASTA)	NCBI Sequence Viewer
	XP_038958357	(Get FASTA)	NCBI Sequence Viewer
	XP_063138007	(Get FASTA)	NCBI Sequence Viewer
	XP_063138008	(Get FASTA)	NCBI Sequence Viewer
	XP_063138009	(Get FASTA)	NCBI Sequence Viewer
	XP_063138010	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL82037	(Get FASTA)	NCBI Sequence Viewer
	EDL82038	(Get FASTA)	NCBI Sequence Viewer
	EDL82039	(Get FASTA)	NCBI Sequence Viewer
	EDL82040	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020757.7
	ENSRNOP00000063437
	ENSRNOP00000063437.4
	ENSRNOP00000097084
	ENSRNOP00000097084.2
	ENSRNOP00000099745.1
	ENSRNOP00000103659.1
	ENSRNOP00000109160
	ENSRNOP00000109160.1

RefSeq Acc Id:	XP_006233290 ⟸ XM_006233228
- Peptide Label:	isoform X3
- UniProtKB:	A6HVA3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSQVLFQQLVPLLVKCKDCEERRGSVRVSIELQSLSNPVHRKDLVIRLTDDTDPFFLYNLVISE EDFQSLKLQQGLLVDFLSFPQKFIDLLQQCMQEHVKETPRFLLQLTSSAALLDNSPVFLNVVET NPFKHLIHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLTKSLDDVTRQLHITQETLSEKMQEL DKLRSEWASHTAALTNKHSQELTNEKEKALQTQVQYQQQHEQQKKDLEALHQRNIHQLQNRLSE LEAANKELTERKYKGDSTVRELKAKLAGVEEELQRTKQEVLSLRRENCTLDTECHEKEKHINQL QTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVALEENGEKNQIQLGKLEATIKSLSAELLKAN EIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEMLQKERKESQDAGQSLRAKEQEVCRLQE QLETTVQKLEESKQLLKNNEKLITWLNKELNENQLGRKQDTLGASATPPTHSASNTVRSGLSPS LNVVDSRLNYPSCGIGYPVSSAFTFQNAFPHAVVAKNTSHPVSGPKVQFSLQLTKQSTSSGDGQ PGAAVNRSASADKEKPSERWHAGSAADIFQTHSPAPIFIVFSWAITK hide sequence

Ensembl Acc Id:

ENSRNOP00000063437 ⟸ ENSRNOT00000067324

RefSeq Acc Id:	XP_038958357 ⟸ XM_039102429
- Peptide Label:	isoform X5
- UniProtKB:	A6HVA2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000020757 ⟸ ENSRNOT00000020757

Ensembl Acc Id:

ENSRNOP00000097084 ⟸ ENSRNOT00000112539

RefSeq Acc Id:	NP_001401987 ⟸ NM_001415058
- UniProtKB:	A0A8I6GMD5 (UniProtKB/TrEMBL), A6HVA1 (UniProtKB/TrEMBL), D3ZVS7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138007 ⟸ XM_063281937
- Peptide Label:	isoform X1
- UniProtKB:	D3ZVS7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138008 ⟸ XM_063281938
- Peptide Label:	isoform X2
- UniProtKB:	D3ZVI7 (UniProtKB/TrEMBL), A6HVA3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138009 ⟸ XM_063281939
- Peptide Label:	isoform X4
- UniProtKB:	A6HVA2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063138010 ⟸ XM_063281940
- Peptide Label:	isoform X6

Ensembl Acc Id:

ENSRNOP00000109160 ⟸ ENSRNOT00000169989

Ensembl Acc Id:

ENSRNOP00000099745 ⟸ ENSRNOT00000152529

Ensembl Acc Id:

ENSRNOP00000103659 ⟸ ENSRNOT00000164886

Protein Domains

SAS-6 coiled-coil Spindle assembly abnormal protein 6 N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZVI7-F1-model_v2	AlphaFold	D3ZVI7	1-568	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306255	AgrOrtholog
BioCyc Gene	G2FUF-51494	BioCyc
Ensembl Genes	ENSRNOG00000015211	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020757.8	UniProtKB/TrEMBL
	ENSRNOT00000067324	ENTREZGENE
	ENSRNOT00000067324.4	UniProtKB/TrEMBL
	ENSRNOT00000112539	ENTREZGENE
	ENSRNOT00000112539.2	UniProtKB/TrEMBL
	ENSRNOT00000152529.1	UniProtKB/TrEMBL
	ENSRNOT00000164886.1	UniProtKB/TrEMBL
	ENSRNOT00000169989	ENTREZGENE
	ENSRNOT00000169989.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.1490	UniProtKB/TrEMBL
	2.170.210.20	UniProtKB/TrEMBL
InterPro	SAS-6_N	UniProtKB/TrEMBL
	SAS-6_N_sf	UniProtKB/TrEMBL
	SAS6_CC	UniProtKB/TrEMBL
NCBI Gene	310807	ENTREZGENE
PANTHER	SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG	UniProtKB/TrEMBL
	SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG	UniProtKB/TrEMBL
Pfam	SAS-6_N	UniProtKB/TrEMBL
	Sas6_CC	UniProtKB/TrEMBL
PhenoGen	Sass6	PhenoGen
RatGTEx	ENSRNOG00000015211	RatGTEx
UniProt	A0A8I6GMD5	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L6Y8_RAT	UniProtKB/TrEMBL
	A0ABK0LFV0_RAT	UniProtKB/TrEMBL
	A0ABK0M5F4_RAT	UniProtKB/TrEMBL
	A6HVA1	ENTREZGENE, UniProtKB/TrEMBL
	A6HVA2	ENTREZGENE, UniProtKB/TrEMBL
	A6HVA3	ENTREZGENE, UniProtKB/TrEMBL
	D3ZVI7	ENTREZGENE, UniProtKB/TrEMBL
	D3ZVS7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Sass6	SAS-6 centriolar assembly protein	LOC102555636	uncharacterized LOC102555636	Data merged from RGD:7671520	737654	PROVISIONAL
2015-06-26	Sass6	SAS-6 centriolar assembly protein	Sass6	spindle assembly 6 homolog (C. elegans)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-12-18	LOC102555636	uncharacterized LOC102555636			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Sass6	spindle assembly 6 homolog (C. elegans)	Sass6_predicted	spindle assembly 6 homolog (C. elegans) (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-30	Sass6_predicted	spindle assembly 6 homolog (C. elegans) (predicted)	RGD1306255_predicted	similar to 2810453L12Rik protein (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-20	RGD1306255_predicted	similar to 2810453L12Rik protein (predicted)	LOC310807_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC310807_predicted	similar to 2810453L12Rik protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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