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Gene: Lhx6 (LIM homeobox 6) Rattus norvegicus

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Symbol:

Lhx6

Name:

LIM homeobox 6

RGD ID:

1306174

Description:

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in forebrain neuron development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within forebrain development and neuron maturation. Predicted to be active in nucleus. Orthologous to human LHX6 (LIM homeobox 6); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LIM homeobox protein 6; LIM/homeobox protein Lhx6; LOC311901

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LHX6 (LIM homeobox 6)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Lhx6 (LIM homeobox protein 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Lhx6 (LIM homeobox 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LHX6 (LIM homeobox 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LHX6 (LIM homeobox 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Lhx6 (LIM homeobox 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LHX6 (LIM homeobox 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LHX6 (LIM homeobox 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Lhx6 (LIM homeobox 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	LHX6 (LIM homeobox 6)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Lhx6 (LIM homeobox protein 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	lhx6 (LIM homeobox 6)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Awh	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	lim-4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	lhx6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	39,829,846 - 39,853,681 (-)	NCBI		GRCr8
mRatBN7.2	3	19,432,439 - 19,456,268 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	19,433,494 - 19,456,061 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	22,510,924 - 22,534,512 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	31,095,849 - 31,119,442 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	29,343,118 - 29,366,747 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	15,409,349 - 15,433,504 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	15,411,939 - 15,433,252 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	20,718,972 - 20,742,583 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	15,192,524 - 15,216,076 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	15,088,870 - 15,113,701 (-)	NCBI
Celera	3	14,144,852 - 14,168,405 (-)	NCBI		Celera
Cytogenetic Map	3	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

actinomycin D (ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

amosite asbestos (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium dichloride (ISO)

camptothecin (ISO)

choline (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

ethanol (ISO)

folic acid (ISO)

furan (EXP)

genistein (ISO)

hydrogen peroxide (ISO)

inulin (ISO)

L-methionine (ISO)

menadione (ISO)

methapyrilene (ISO)

niclosamide (ISO)

Nutlin-3 (ISO)

paracetamol (ISO)

pentanal (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

propanal (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sotorasib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trametinib (ISO)

trichloroethene (EXP,ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cerebral cortex GABAergic interneuron migration (ISO)

cerebral cortex neuron differentiation (ISO)

cerebral cortex radially oriented cell migration (ISO)

cerebral cortex tangential migration (ISO)

forebrain neuron development (IBA,ISO)

forebrain neuron fate commitment (ISO)

neuron differentiation (IBA)

neuron maturation (ISO)

neuron migration (ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IBA)

system development (IEA)

Cellular Component

nucleus (IBA,IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA)

sequence-specific double-stranded DNA binding (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:15217369	PMID:17376969	PMID:18339674	PMID:20075618	PMID:32931819	PMID:38531158

Genomics

Comparative Map Data

Lhx6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	39,829,846 - 39,853,681 (-)	NCBI		GRCr8
mRatBN7.2	3	19,432,439 - 19,456,268 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	19,433,494 - 19,456,061 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	22,510,924 - 22,534,512 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	31,095,849 - 31,119,442 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	29,343,118 - 29,366,747 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	15,409,349 - 15,433,504 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	15,411,939 - 15,433,252 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	20,718,972 - 20,742,583 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	15,192,524 - 15,216,076 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	15,088,870 - 15,113,701 (-)	NCBI
Celera	3	14,144,852 - 14,168,405 (-)	NCBI		Celera
Cytogenetic Map	3	p11	NCBI

LHX6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	122,202,582 - 122,228,957 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	122,202,577 - 122,229,626 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	124,964,861 - 124,991,236 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	124,004,679 - 124,030,840 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	9	95,613,158 - 95,639,326 (-)	NCBI		Celera
Cytogenetic Map	9	q33.2	NCBI
HuRef	9	94,579,638 - 94,605,760 (-)	NCBI		HuRef
CHM1_1	9	125,112,910 - 125,139,147 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	134,400,069 - 134,426,451 (-)	NCBI		T2T-CHM13v2.0

Lhx6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	35,971,962 - 35,996,004 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	35,971,965 - 35,995,420 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	36,081,950 - 36,105,992 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	36,081,953 - 36,105,408 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	35,937,473 - 35,960,928 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	35,905,548 - 35,927,280 (-)	NCBI		MGSCv36	mm8
Celera	2	35,785,674 - 35,809,139 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	24.17	NCBI

Lhx6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	5,834,547 - 5,858,113 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	5,835,230 - 5,858,096 (+)	NCBI	ChiLan1.0	ChiLan1.0

LHX6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	17,117,476 - 17,172,379 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	17,119,825 - 17,174,732 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	93,303,447 - 93,353,896 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	121,668,585 - 121,693,605 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	121,670,707 - 121,694,378 (-)	Ensembl	panpan1.1		panPan2

LHX6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	60,348,529 - 60,374,037 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	60,348,335 - 60,374,024 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	59,543,996 - 59,581,491 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	61,263,724 - 61,301,199 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	61,263,679 - 61,289,115 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	60,037,892 - 60,075,327 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	60,354,214 - 60,391,774 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	60,442,894 - 60,480,404 (+)	NCBI		UU_Cfam_GSD_1.0

Lhx6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	190,823,007 - 190,847,434 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936487	10,591,532 - 10,616,017 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936487	10,591,532 - 10,616,017 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LHX6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	262,295,353 - 262,322,530 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	262,297,557 - 262,322,777 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	294,597,333 - 294,622,577 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LHX6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	17,364,693 - 17,392,756 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	12	17,366,826 - 17,386,276 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666035	25,656,604 - 25,683,197 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Lhx6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624760	13,066,703 - 13,097,468 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624760	13,066,632 - 13,092,006 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Lhx6
143 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	65
Count of miRNA genes:	59
Interacting mature miRNAs:	63
Transcripts:	ENSRNOT00000008817
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358357	Srcrtb1	Stress Responsive Cort Basal QTL 1	6.36	0.002	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	8658162	27494778	Rat
6893355	Bw101	Body weight QTL 101	0.4	0.38	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
634306	Bp140	Blood pressure QTL 140	3.3	0.0013	arterial blood pressure trait (VT:2000000)	body weight (CMO:0000012)	3	17374703	35528639	Rat
10401810	Kidm53	Kidney mass QTL 53			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	8227194	47233430	Rat
1298526	Arunc3	Aerobic running capacity QTL 3	2.2		exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	8227194	33703538	Rat
8693641	Alc30	Alcohol consumption QTL 30	2	0.739	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	3	10434306	24512004	Rat
2298542	Neuinf11	Neuroinflammation QTL 11	3.9		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	3	15005422	76927699	Rat
1558657	Cm43	Cardiac mass QTL 43	6.6	3e-08	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
631568	Bp92	Blood pressure QTL 92	2.2	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	39874793	Rat
6893363	Bw105	Body weight QTL 105	2.6	0.0036	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
61468	Bp15	Blood pressure QTL 15	4.4		blood pressure trait (VT:0000183)	pulse pressure (CMO:0000292)	3	1	33278763	Rat
631831	Alc8	Alcohol consumption QTL 8	2.7		consumption behavior trait (VT:0002069)	calculated ethanol drink intake rate (CMO:0001615)	3	1	33230976	Rat
1558647	Cm46	Cardiac mass QTL 46	5.4	0.0000055	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	10778823	30356773	Rat
4889966	Bss95	Bone structure and strength QTL 95	4.4		tibia area (VT:1000281)	tibia-fibula cross-sectional area (CMO:0001718)	3	1	36847613	Rat
12879852	Cm93	Cardiac mass QTL 93		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	18311454	47233430	Rat
1558654	Bw56	Body weight QTL 56	4.5	0.0000171	body mass (VT:0001259)	body weight (CMO:0000012)	3	10778704	30357018	Rat
12879853	Am5	Aortic mass QTL 5		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	18311454	47233430	Rat
12879854	Kidm63	Kidney mass QTL 63		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	18311454	47233430	Rat
1558650	Cm48	Cardiac mass QTL 48	4	0.0001	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	3	10778823	30356773	Rat
1358905	Hrtrt17	Heart rate QTL 17	5.9	0.000014	heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	3	10861912	89878372	Rat
12879849	Bw180	Body weight QTL 180		0.037	body mass (VT:0001259)	body weight (CMO:0000012)	3	18311454	47233430	Rat
70191	BpQTLcluster4	Blood pressure QTL cluster 4	3		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	3	10778704	50302886	Rat
12879850	Cm91	Cardiac mass QTL 91		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	18311454	47233430	Rat
731172	Bp151	Blood pressure QTL 151		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	18311454	47233430	Rat
12879851	Cm92	Cardiac mass QTL 92		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	18311454	47233430	Rat
631545	Bp85	Blood pressure QTL 85	3.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	1	33278763	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2325840	Bp345	Blood pressure QTL 345		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	18311454	28441896	Rat
631676	Cm8	Cardiac mass QTL 8	7.03	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	3	16954708	61954708	Rat
631679	Cm10	Cardiac mass QTL 10	7.34	0.0001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	1	31158234	Rat
2290452	Scl56	Serum cholesterol level QTL 56	2.26		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	3	1	91609953	Rat
70203	Gcr2	Gastric cancer resistance QTL 2	2.6		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	3	8658162	27494778	Rat
70202	Alc19	Alcohol consumption QTL 19	2.5		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	3	1	27494778	Rat
2312664	Scl62	Serum cholesterol level QTL 62		0.05	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	1	38710544	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat

Markers in Region

D2Mit372

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	19,452,454 - 19,452,553 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	15,429,750 - 15,429,848	NCBI	Rnor6.0
Rnor_5.0	3	20,738,962 - 20,739,060	UniSTS	Rnor5.0
RGSC_v3.4	3	15,212,514 - 15,212,612	UniSTS	RGSC3.4
Celera	3	14,164,843 - 14,164,941	UniSTS
Cytogenetic Map	3	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
7	11	49	109	87	86	56	24	56	6	209	96	89	42	60	30

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107837	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006234066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105262	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105263	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039105264	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000008817 ⟹ ENSRNOP00000008817

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	19,433,494 - 19,456,061 (-)	Ensembl
Rnor_6.0 Ensembl	3	15,411,939 - 15,433,252 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000093874 ⟹ ENSRNOP00000097190

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	19,433,494 - 19,456,061 (-)	Ensembl

RefSeq Acc Id:

NM_001107837 ⟹ NP_001101307

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	39,829,871 - 39,853,423 (-)	NCBI
mRatBN7.2	3	19,432,464 - 19,456,017 (-)	NCBI
Rnor_6.0	3	15,409,760 - 15,433,315 (-)	NCBI
Rnor_5.0	3	20,718,972 - 20,742,583 (-)	NCBI
RGSC_v3.4	3	15,192,524 - 15,216,076 (-)	RGD
Celera	3	14,144,852 - 14,168,405 (-)	RGD

Sequence:

show sequence

CGAGGCCCCACTCCGTGCTGCTCTTTGCGCTGCGCGCCCTTCGAGCCCTCAGTTCCCGGGCCCA
TGTACTGGAAGCATGAGAGCGCCGCCCCGGGCTGCCGGTTACCGGCGGAGGGCGGCCCCACCAC
CGACCAGGTGATGGCCCAGCCAGGGTCCGGCTGCAAAGCGACCACCCGCTGTCTTGAAGGGACC
GCTCCGCCTGCCATGGCTCAGTCAGACGCCGAGGCCTTGGCAGGCGCTCTGGACAAGGACGAAG
GTAGAGCCTCCCCATGTACGCCCAGCACACCCTCTGTCTGCTCGCCGCCCTCTGCCGCCTCTTC
CGTGCCGTCTGCTGGCAAGAATATCTGCTCCAGTTGCGGTCTCGAGATCCTGGACCGGTATCTG
CTCAAGGTCAACAACCTCATCTGGCACGTGCGGTGCCTCGAGTGCTCCGTGTGTCGCACATCGC
TGAGGCAGCAGAATAGCTGCTACATCAAGAACAAGGAGATCTACTGCAAGATGGACTACTTCAG
CCGATTTGGAACCAAGTGTGCCCGGTGCGGCAGACAAATCTATGCCAGTGACTGGGTGCGGCGC
GCGCGCGGCAATGCCTACCACCTGGCCTGCTTCGCTTGCTTTTCCTGCAAGCGCCAGCTATCCA
CGGGCGAGGAATTCGGCCTGGTTGAGGAGAAGGTGCTTTGCCGCATCCATTACGACACCATGAT
CGAGAACCTCAAGAGGGCCGCCGAGAACGGGAACGGTCTCACGTTGGAGGGGGCAGTGCCCTCG
GAACAGGACAGTCAGCCCAAGCCAGCTAAGCGCGCGCGGACGTCCTTCACGGCAGAGCAATTGC
AGGTTATGCAGGCTCAGTTCGCGCAGGACAACAACCCCGACGCGCAGACGCTGCAGAAGCTAGC
GGACATGACGGGCCTCAGTCGCAGGGTCATCCAGGTGTGGTTTCAAAACTGCCGAGCGCGTCAT
AAAAAGCATACACCGCAGCACCCAGTGCCGCCCTCTGGGGCACCCCCGTCCCGCCTCCCCTCCT
CCCTGTCCGACGACATCCACTATTCTCCGTTCAGCAGCCCAGAGCGGGCACGCATGGTCACCTT
GCACGGCTACATCGAGAGTCAGGTACAGTGCGGGCAGGTGCACTGCCGACTGCCTTACACCGCG
CCCCCTGTCCACCTCAAAGCCGACATGGATGGGCCGCTCTCCAGCCGGGGTGAGAAGGTCATCC
TTTTTCAGTACTAACTCTGCCGGCGCTTGCACATCTGTCCATGGGCACCACACAGCTGCCCCTC
AGCCGCTGAGCATCCAGCGTCCAGCTGTGGCCAGGGATCCACCGCCTCTGGGCACACCCTCCTC
ACCCGCTGCCGCCCTGCCCTCTGCCAGTGGCCCCATCAACCCAGCCCCGGTATTTCCCTCTCCT
GCTGAGAACCAGAACCCGCCAGGAGCAGCAGAGCCCTCTCTGGGAAGGCAGGCTCCCTGAAATG
TGGTATCAGCATGAAAACAAGCAGCCTGTCTTTCCTCATCATCTGGGAGTCTTGCTTATCTGGG
AGTCAGCTGATCGCAGCAGCAACAGCTAATTCAACAACAGCCTCCCACTTCACAGGTTTTCTTC
TTCCCCCATATTGGCCTTCATTTACTACTTCCTTGGAACCGTCTCTGAGTTCTGAACAGCCAAA
ACAACCCCCAACATTATATACTCCGCTGCTTTTGTCTGGAAAACTCTACAGTGTTTGTGGGATG
TCCCCAAAGGAAAGCCGTGTTCTGATTTTATCATTTCCATCTGTCTGGTTATGTCAAGTTAACT
CAGAAAAAGAAGAGACACTGACCAACCCTGAGAGGCCCAACAGGGCAGAGATGGAGGCCTGCCC
AGATGAAGAGGCAGAGGGATGGGCAGGGATGGGTGCCAAAGACCCCCCATTGGCTTGGAGAAGG
AGGACTGGGTATGCTGGACTTGGAGAGGTGATGAGAGTTTCATGGAGAGAAAAGAGGAAACTTG
AGGGGGGGTGTCCCCCACCTAATTACCCAGCAGGAGTTGTGGAAAGAATGGCGTCTGATCGGCA
CGATGACACCACTGAATGTTTAGGTGGGCTAGCATTAGGGACCCTTGTTGGCCACTTTTCAGTC
CTGAGATGAGGGCCTGAGCCAGTCTTCTCTGGGGGTGGGGTGAGACTACTCATGAGGACCAAGG
AACAGAGCCCAGAGAAATAGCAGCCATGATATTAGCTCGGATTCATCCACGAGGGGAGAGAGGT
GCCCGTGGCCTCAGTGAGTGCGTGCCAAGCCCAGGATTCCAGCTGGCACCTCGGCAGTCTCCCC
ACCAACTGCACAGAGCCAGCTCTACCCACTCCTGAGAGCAGAGGCCAGCTCCAAATAAAGGTCT
CAGGTTACACAGGCCCTCGATTCATGTTTTCAGGGGGTGCCCATCTGCCCCGAGCTTATCCTGT
AATTCTACAACCACTTGGTGGCCTGATGCACTACTCACCAGAGGCTGCCTAGCAGCGTGTGTTA
GCCAAAGTCTTCCTCCCTGTTTTGAGGAGACTCCAGGTCAGGAAAGGCAAATTCCGAGTCTGTA
TGCTGTCCCTCCTTCACCTGTGGCAGACATCACTAATCGCTAATCGATCACACCTCTCTCTCTC
TCTCTCTCTCTCTCTCTCTCTCTCTCGCTCTCGCTCTCGCTCTCGCTCTCGCTCTCGCTCTCGC
TCTCTCTCGCTTTCTCTCGCTCTCGGAGTCTGGATAAGGTTTCAGAATTCCCAAGCTTGAAGTT
GGGATGTGACCAACTGTGCTATTGCTGAAGGACCTGGAGGAGGGTTAGGCCTGGGTGACCCCCC
AGAAGGGAACTTGCATCTTTTCCCTTCCAAAAATTGTCAACTGACGGAGGACAGAGAGAAAGTT
CCTCCCAGAAAGCTGAGAGTGTGGTTCATTCCGGTCAGAACTCCAGCACCCTGTGCCAGGCACT
GACTCAAGCAAGAGGAACCTGGCCTGATCCCTGACTTGGGGAACCCAGATATTCCCTTTGATTT
ATTTTGCTCCTAAGGATCAAAACCCCCAGTTGCAACCATGTGGCAAGTGGCCAGCTGAGCCCAG
GTTACTTGGTACCCACTCTGCCTTGAGCCTTCCCCCAGGGTCTATTTCTTGTGTGGATCACGTG
GCAGTAGCATGTTGCAGTTCAGACGTCTCCACTACTCTGTTCAAAACAGCCTGGGAATGTACAG
GCCATTGAGGCTATTTATTTAAATACACACACACACACACACACACACACACACACACATGCGC
ACACACAAAGGGGGGAACACACACAAATGGAAACAATTGTAAGCACTTTTTTTTGTAAAACCAA
TGTCTGTTTTGTTACATACCTTTCATGTTGTGCTTTGTAAATGTCTTATTTGTGTAATAAATAA
AGTTAATGCGAGTAG

hide sequence

RefSeq Acc Id:

XM_006234066 ⟹ XP_006234128

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	39,829,846 - 39,853,677 (-)	NCBI
mRatBN7.2	3	19,432,439 - 19,456,263 (-)	NCBI
Rnor_6.0	3	15,409,349 - 15,433,504 (-)	NCBI
Rnor_5.0	3	20,718,972 - 20,742,583 (-)	NCBI

Sequence:

show sequence

CAGCCGCAGAGGCAGCTGCAGGGACCTCTCCAAGTTTGTCGGGACCTTCTTCAGAGGCAGTGGT
GCCGGCAGCCAGGGAGGCCAGGACTGCGCTCAGACCGGGGGAGGAGGGCTGGGGCTGGGCCCGG
GGCGGCGGGGCCGGAGCCTGGGTTCTCCAGCTCTCGCATCAGCCTCTGCCCACAGGGCGCCCGA
GGCCCCACTCCGTGCTGCTCTTTGCGCTGCGCGCCCTTCGAGCCCTCAGTTCCCGGGCCCATGT
ACTGGAAGCATGAGAGCGCCGCCCCGGCGCTGCCCGAGGGCTGCCGGTTACCGGCGGAGGGCGG
CCCCACCACCGACCAGGTGATGGCCCAGCCAGGGTCCGGCTGCAAAGCGACCACCCGCTGTCTT
GAAGGGACCGCTCCGCCTGCCATGGCTCAGTCAGACGCCGAGGCCTTGGCAGGCGCTCTGGACA
AGGACGAAGGTAGAGCCTCCCCATGTACGCCCAGCACACCCTCTGTCTGCTCGCCGCCCTCTGC
CGCCTCTTCCGTGCCGTCTGCTGGCAAGAATATCTGCTCCAGTTGCGGTCTCGAGATCCTGGAC
CGGTATCTGCTCAAGGTCAACAACCTCATCTGGCACGTGCGGTGCCTCGAGTGCTCCGTGTGTC
GCACATCGCTGAGGCAGCAGAATAGCTGCTACATCAAGAACAAGGAGATCTACTGCAAGATGGA
CTACTTCAGCCGATTTGGAACCAAGTGTGCCCGGTGCGGCAGACAAATCTATGCCAGTGACTGG
GTGCGGCGCGCGCGCGGCAATGCCTACCACCTGGCCTGCTTCGCTTGCTTTTCCTGCAAGCGCC
AGCTATCCACGGGCGAGGAATTCGGCCTGGTTGAGGAGAAGGTGCTTTGCCGCATCCATTACGA
CACCATGATCGAGAACCTCAAGAGGGCCGCCGAGAACGGGAACGGTCTCACGTTGGAGGGGGCA
GTGCCCTCGGAACAGGACAGTCAGCCCAAGCCAGCTAAGCGCGCGCGGACGTCCTTCACGGCAG
AGCAATTGCAGGTTATGCAGGCTCAGTTCGCGCAGGACAACAACCCCGACGCGCAGACGCTGCA
GAAGCTAGCGGACATGACGGGCCTCAGTCGCAGGGTCATCCAGGTGTGGTTTCAAAACTGCCGA
GCGCGTCATAAAAAGCATACACCGCAGCACCCAGTGCCGCCCTCTGGGGCACCCCCGTCCCGCC
TCCCCTCCTCCCTGTCCGACGACATCCACTATTCTCCGTTCAGCAGCCCAGAGCGGGCACGCAT
GGTCACCTTGCACGGCTACATCGAGAGTCATCCTTTTTCAGTACTAACTCTGCCGGCGCTTGCA
CATCTGTCCATGGGCACCACACAGCTGCCCCTCAGCCGCTGAGCATCCAGCGTCCAGCTGTGGC
CAGGGATCCACCGCCTCTGGGCACACCCTCCTCACCCGCTGCCGCCCTGCCCTCTGCCAGTGGC
CCCATCAACCCAGCCCCGGTATTTCCCTCTCCTGCTGAGAACCAGAACCCGCCAGGAGCAGCAG
AGCCCTCTCTGGGAAGGCAGGCTCCCTGAAATGTGGTATCAGCATGAAAACAAGCAGCCTGTCT
TTCCTCATCATCTGGGAGTCTTGCTTATCTGGGAGTCAGCTGATCGCAGCAGCAACAGCTAATT
CAACAACAGCCTCCCACTTCACAGGTTTTCTTCTTCCCCCATATTGGCCTTCATTTACTACTTC
CTTGGAACCGTCTCTGAGTTCTGAACAGCCAAAACAACCCCCAACATTATATACTCCGCTGCTT
TTGTCTGGAAAACTCTACAGTGTTTGTGGGATGTCCCCAAAGGAAAGCCGTGTTCTGATTTTAT
CATTTCCATCTGTCTGGTTATGTCAAGTTAACTCAGAAAAAGAAGAGACACTGACCAACCCTGA
GAGGCCCAACAGGGCAGAGATGGAGGCCTGCCCAGATGAAGAGGCAGAGGGATGGGCAGGGATG
GGTGCCAAAGACCCCCCATTGGCTTGGAGAAGGAGGACTGGGTATGCTGGACTTGGAGAGGTGA
TGAGAGTTTCATGGAGAGAAAAGAGGAAACTTGAGGGGGGGTGTCCCCCACCTAATTACCCAGC
AGGAGTTGTGGAAAGAATGGCGTCTGATCGGCACGATGACACCACTGAATGTTTAGGTGGGCTA
GCATTAGGGACCCTTGTTGGCCACTTTTCAGTCCTGAGATGAGGGCCTGAGCCAGTCTTCTCTG
GGGGTGGGGTGAGACTACTCATGAGGACCAAGGAACAGAGCCCAGAGAAATAGCAGCCATGATA
TTAGCTCGGATTCATCCACGAGGGGAGAGAGGTGCCCGTGGCCTCAGTGAGTGCGTGCCAAGCC
CAGGATTCCAGCTGGCACCTCGGCAGTCTCCCCACCAACTGCACAGAGCCAGCTCTACCCACTC
CTGAGAGCAGAGGCCAGCTCCAAATAAAGGTCTCAGGTTACACAGGCCCTCGATTCATGTTTTC
AGGGGGTGCCCATCTGCCCCGAGCTTATCCTGTAATTCTACAACCACTTGGTGGCCTGATGCAC
TACTCACCAGAGGCTGCCTAGCAGCGTGTGTTAGCCAAAGTCTTCCTCCCTGTTTTGAGGAGAC
TCCAGGTCAGGAAAGGCAAATTCCGAGTCTGTATGCTGTCCCTCCTTCACCTGTGGCAGACATC
ACTAATCGCTAATCGATCACACCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
CTGTCTCTCGCTCTCGCTCTCGCTCTCGCTCTCGCTCTCTCTCGCTTTCTCTCGCTCTCGGAGT
CTGGATAAGGTTTCAGAATTCCCAAGCTTGAAGTTGGGATGTGACCAACTGTGCTATTGCTGAA
GGACCTGGAGGAGGGTTAGGCCTGGGTGACCCCCCAGAAGGGAACTTGCATCTTTTCCCTTCCA
AAAATTGTCAACTGACGGAGGACAGAGAGAAAGTTCCTCCCAGAAAGCTGAGAGTGTGGTTCAT
TCCGGTCAGAACTCCAGCACCCTGTGCCAGGCACTGACTCAAGCAAGAGGAACCTGGCCTGATC
CCTGACTTGGGGAACCCAGATATTCCCTTTGATTTATTTTGCTCCTAAGGATCAAAACCCCCAG
TTGCAACCATGTGGCAAGTGGCCAGCTGAGCCCAGGTTACTTGGTACCCACTCTGCCTTGAGCC
TTCCCCCAGGGTCTATTTCTTGTGTGGATCACGTGGCAGTAGCATGTTGCAGTTCAGACGTCTC
CACTACTCTGTTCAAAACAGCCTGGGAATGTACAGGCCATTGAGGCTATTTATTTAAATACACA
CACACACACACACACACACACACACACACATGCGCACACACAAAGGGGGGAACACACACAAATG
GAAACAATTGTAAGCACTTTTTTTTGTAAAACCAATGTCTGTTTTGTTACATACCTTTCATGTT
GTGCTTTGTAAATGTCTTATTTGTGTAATAAATAAAGTTAATGCGAGTAGAAGTGCCGGCACTT
AAACCCAAAAACGCGATGGGATTCCATTTTTCTCTTGATAAACCCTTGTCCCCGGCTTTGGTGT
GAGCTGCTCCGTGTAATCCTAGGAAACTGGTCCCACGGGCAGTGGACTGAGGCACTCTGCTGAG
GTACAGTGATGGGTTTCTACTCTAATACTGTGCTGCCTCTGTGTGTTGACTACTTTGTGGCAAG
TCCGGCTGCTTGCTGACCTCTGTTCTGCTTTCTAAACACCAACAGTCTGTCATGTCCTGTGCTG
CTCTGCAAACTCAGAGAGTCCAGTCCTACCCTGCCTTGGAGAAACTGTCAGCCGACATCCCTCT
AGTATGCTAGAGGCCTGGGGCGTGGGCGTGTATCTGAGCTGGATCCAATCTAGTAAGATTTGTA
GAGTAGGTATGAA

hide sequence

RefSeq Acc Id:

XM_039105262 ⟹ XP_038961190

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	39,829,846 - 39,853,129 (-)	NCBI
mRatBN7.2	3	19,432,439 - 19,455,721 (-)	NCBI

RefSeq Acc Id:

XM_039105263 ⟹ XP_038961191

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	39,829,846 - 39,853,680 (-)	NCBI
mRatBN7.2	3	19,432,439 - 19,456,267 (-)	NCBI

RefSeq Acc Id:

XM_039105264 ⟹ XP_038961192

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	39,839,815 - 39,853,681 (-)	NCBI
mRatBN7.2	3	19,442,413 - 19,456,268 (-)	NCBI

RefSeq Acc Id:

XM_063283972 ⟹ XP_063140042

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	39,829,846 - 39,853,123 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001101307	(Get FASTA)	NCBI Sequence Viewer
	XP_006234128	(Get FASTA)	NCBI Sequence Viewer
	XP_038961190	(Get FASTA)	NCBI Sequence Viewer
	XP_038961191	(Get FASTA)	NCBI Sequence Viewer
	XP_038961192	(Get FASTA)	NCBI Sequence Viewer
	XP_063140042	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL93130	(Get FASTA)	NCBI Sequence Viewer
	EDL93131	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000008817
	ENSRNOP00000008817.4
	ENSRNOP00000097190
	ENSRNOP00000097190.1

RefSeq Acc Id:

NP_001101307 ⟸ NM_001107837

- UniProtKB:

D3ZDG6 (UniProtKB/TrEMBL), A6JUG7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYWKHESAAPGCRLPAEGGPTTDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGALDKDE
GRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTS
LRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLS
TGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFTAEQL
QVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPSRLPS
SLSDDIHYSPFSSPERARMVTLHGYIESQVQCGQVHCRLPYTAPPVHLKADMDGPLSSRGEKVI
LFQY

hide sequence

RefSeq Acc Id:	XP_006234128 ⟸ XM_006234066
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AN85 (UniProtKB/TrEMBL), A6JUG6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MYWKHESAAPALPEGCRLPAEGGPTTDQVMAQPGSGCKATTRCLEGTAPPAMAQSDAEALAGAL DKDEGRASPCTPSTPSVCSPPSAASSVPSAGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSV CRTSLRQQNSCYIKNKEIYCKMDYFSRFGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCK RQLSTGEEFGLVEEKVLCRIHYDTMIENLKRAAENGNGLTLEGAVPSEQDSQPKPAKRARTSFT AEQLQVMQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPPSGAPPS RLPSSLSDDIHYSPFSSPERARMVTLHGYIESHPFSVLTLPALAHLSMGTTQLPLSR hide sequence

Ensembl Acc Id:

ENSRNOP00000008817 ⟸ ENSRNOT00000008817

RefSeq Acc Id:	XP_038961191 ⟸ XM_039105263
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038961190 ⟸ XM_039105262
- Peptide Label:	isoform X2
- UniProtKB:	A6JUG7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038961192 ⟸ XM_039105264
- Peptide Label:	isoform X4

Ensembl Acc Id:

ENSRNOP00000097190 ⟸ ENSRNOT00000093874

RefSeq Acc Id:	XP_063140042 ⟸ XM_063283972
- Peptide Label:	isoform X5
- UniProtKB:	A6JUG6 (UniProtKB/TrEMBL)

Protein Domains

Homeobox LIM zinc-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZDG6-F1-model_v2	AlphaFold	D3ZDG6	1-392	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306174	AgrOrtholog
BioCyc Gene	G2FUF-50015	BioCyc
Ensembl Genes	ENSRNOG00000005996	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000008817	ENTREZGENE
	ENSRNOT00000008817.5	UniProtKB/TrEMBL
	ENSRNOT00000093874	ENTREZGENE
	ENSRNOT00000093874.1	UniProtKB/TrEMBL
Gene3D-CATH	Cysteine Rich Protein	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Homeobox_CS	UniProtKB/TrEMBL
	Homeodomain	UniProtKB/TrEMBL
	Homeodomain-like	UniProtKB/TrEMBL
	LIM_Homeobox_TF	UniProtKB/TrEMBL
	Znf_LIM	UniProtKB/TrEMBL
KEGG Report	rno:311901	UniProtKB/TrEMBL
NCBI Gene	311901	ENTREZGENE
PANTHER	LIM/HOMEOBOX PROTEIN LHX	UniProtKB/TrEMBL
	LIM/HOMEOBOX PROTEIN LHX6	UniProtKB/TrEMBL
Pfam	Homeobox	UniProtKB/TrEMBL
	LIM	UniProtKB/TrEMBL
PhenoGen	Lhx6	PhenoGen
PROSITE	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
	LIM_DOMAIN_1	UniProtKB/TrEMBL
	LIM_DOMAIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005996	RatGTEx
SMART	HOX	UniProtKB/TrEMBL
	LIM	UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/TrEMBL
	Homeodomain_like	UniProtKB/TrEMBL
UniProt	A0A8I6AN85	ENTREZGENE, UniProtKB/TrEMBL
	A6JUG6	ENTREZGENE, UniProtKB/TrEMBL
	A6JUG7	ENTREZGENE, UniProtKB/TrEMBL
	D3ZDG6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-26	Lhx6	LIM homeobox 6	Lhx6	LIM homeobox protein 6	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Lhx6	LIM homeobox protein 6	Lhx6_predicted	LIM homeobox protein 6 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Lhx6_predicted	LIM homeobox protein 6 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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