Predicted to enable cytokine activity and type I interferon receptor binding activity. Involved in defense response to virus. Predicted to be located in membrane. Predicted to be active in extracellular space. Biomarker of osteoarthritis. Orthologous to human IFNA13 (interferon alpha 13); PARTICIPATES IN autoimmune thyroiditis pathway; autophagy pathway; cytokine mediated signaling pathway; INTERACTS WITH 2-acetamidofluorene; acrylamide; ammonium chloride.
IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA] more ...
IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of FLT1 protein] and IFNA1 protein promotes the reaction [Fluorouracil results in decreased expression of RGS5 mRNA]
[Dacarbazine co-treated with IFNA1 protein] results in increased expression of CD38 protein and Dacarbazine promotes the reaction [IFNA1 protein results in increased expression of CD38 protein]
IFNA1 protein inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CDKN1A mRNA] more ...
ruxolitinib inhibits the reaction [IFNA1 protein affects the localization of and results in increased phosphorylation of STAT1 protein] and ruxolitinib inhibits the reaction [IFNA1 protein affects the localization of and results in increased phosphorylation of STAT2 protein]
ursodoxicoltaurine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 mRNA] and ursodoxicoltaurine inhibits the reaction [IFNA1 protein results in decreased expression of NR3C1 protein]
[Carbon Tetrachloride co-treated with Tamoxifen] affects the expression of IFNA1 mRNA and IFNA1 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A2 mRNA]
tofacitinib inhibits the reaction [IFNA1 protein affects the localization of and results in increased phosphorylation of STAT1 protein] and tofacitinib inhibits the reaction [IFNA1 protein affects the localization of and results in increased phosphorylation of STAT2 protein]
Effects of long-term postoperative interferon-alpha therapy on intrahepatic recurrence after resection of hepatitis C virus-related hepatocellular carcinoma. A randomized, controlled trial.
Downregulation of long noncoding RNA LOC101928134 inhibits the synovial hyperplasia and cartilage destruction of osteoarthritis rats through the activation of the Janus kinase/signal transducers and activators of transcription signaling pathway by upregulating IFNA1.