Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sugp2 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Sugp2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of SUGP2 mRNA | CTD | PMID:22206623 | Sugp2 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Sugp2 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of SUGP2 mRNA | CTD | PMID:17555576 | Sugp2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of SUGP2 mRNA | CTD | PMID:21346803 | Sugp2 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of SUGP2 mRNA | CTD | PMID:21346803 | Sugp2 | Rat | 2-methylcholine | affects expression | ISO | SUGP2 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of SUGP2 mRNA | CTD | PMID:21179406 | Sugp2 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SUGP2 mRNA more ... | CTD | PMID:28628672 | Sugp2 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Sugp2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of SUGP2 mRNA | CTD | PMID:18648102 | Sugp2 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of SUGP2 mRNA | CTD | PMID:28628672 | Sugp2 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SUGP2 mRNA | CTD | PMID:36041667 | Sugp2 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Decitabine affects the expression of SUGP2 mRNA | CTD | PMID:23300844 | Sugp2 | Rat | acrolein | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SUGP2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SUGP2 mRNA | CTD | PMID:32699268 | Sugp2 | Rat | aflatoxin B1 | increases expression | ISO | Sugp2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of SUGP2 mRNA | CTD | PMID:19770486 | Sugp2 | Rat | alpha-pinene | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SUGP2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SUGP2 mRNA | CTD | PMID:32699268 | Sugp2 | Rat | AM-251 | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | AM 251 results in decreased expression of SUGP2 mRNA | CTD | PMID:16500647 | Sugp2 | Rat | benzo[a]pyrene | increases expression | ISO | Sugp2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SUGP2 mRNA | CTD | PMID:22228805 | Sugp2 | Rat | benzo[a]pyrene | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of SUGP2 mRNA | CTD | PMID:20064835 | Sugp2 | Rat | beta-lapachone | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of SUGP2 mRNA | CTD | PMID:38218311 | Sugp2 | Rat | bisphenol A | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SUGP2 mRNA | CTD | PMID:28628672 | Sugp2 | Rat | bisphenol A | decreases expression | ISO | Sugp2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SUGP2 mRNA | CTD | PMID:32156529 | Sugp2 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SUGP2 mRNA | CTD | PMID:36041667 | Sugp2 | Rat | bisphenol F | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SUGP2 mRNA | CTD | PMID:28628672 | Sugp2 | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of SUGP2 mRNA | CTD | PMID:36041667 | Sugp2 | Rat | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of SUGP2 protein | CTD | PMID:28903499 | Sugp2 | Rat | butanal | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of SUGP2 mRNA | CTD | PMID:26079696 | Sugp2 | Rat | caffeine | affects phosphorylation | ISO | SUGP2 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of SUGP2 protein | CTD | PMID:35688186 | Sugp2 | Rat | cisplatin | affects expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Cisplatin affects the expression of SUGP2 mRNA | CTD | PMID:23300844 | Sugp2 | Rat | cobalt dichloride | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of SUGP2 mRNA | CTD | PMID:19376846 | Sugp2 | Rat | copper(II) sulfate | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SUGP2 mRNA | CTD | PMID:19549813 | Sugp2 | Rat | crocidolite asbestos | increases expression | ISO | Sugp2 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in increased expression of SUGP2 mRNA | CTD | PMID:29279043 | Sugp2 | Rat | crocidolite asbestos | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Asbestos and Crocidolite results in decreased expression of SUGP2 mRNA | CTD | PMID:29523930 | Sugp2 | Rat | dexamethasone | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SUGP2 mRNA more ... | CTD | PMID:28628672 | Sugp2 | Rat | Dibutyl phosphate | affects expression | ISO | SUGP2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of SUGP2 mRNA | CTD | PMID:37042841 | Sugp2 | Rat | dorsomorphin | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Sugp2 | Rat | doxorubicin | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SUGP2 mRNA | CTD | PMID:29803840 | Sugp2 | Rat | enzyme inhibitor | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of SUGP2 protein | CTD | PMID:23301498 | Sugp2 | Rat | ethanol | affects splicing | ISO | Sugp2 (Mus musculus) | 6480464 | Ethanol affects the splicing of SUGP2 mRNA | CTD | PMID:30319688 | Sugp2 | Rat | fenthion | decreases expression | ISO | Sugp2 (Mus musculus) | 6480464 | Fenthion results in decreased expression of SUGP2 mRNA | CTD | PMID:34813904 | Sugp2 | Rat | FR900359 | increases phosphorylation | ISO | SUGP2 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of SUGP2 protein | CTD | PMID:37730182 | Sugp2 | Rat | indometacin | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of SUGP2 mRNA more ... | CTD | PMID:28628672 | Sugp2 | Rat | ivermectin | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SUGP2 protein | CTD | PMID:32959892 | Sugp2 | Rat | leflunomide | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of SUGP2 mRNA | CTD | PMID:28988120 | Sugp2 | Rat | methotrexate | increases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of SUGP2 mRNA | CTD | PMID:17400583 | Sugp2 | Rat | methylmercury chloride | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of SUGP2 mRNA | CTD | PMID:28001369 | Sugp2 | Rat | ozone | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SUGP2 mRNA more ... | CTD | PMID:32699268 | Sugp2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SUGP2 mRNA | CTD | PMID:33387578 | Sugp2 | Rat | resveratrol | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SUGP2 mRNA | CTD | PMID:23557933 | Sugp2 | Rat | SB 431542 | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | Sugp2 | Rat | sodium arsenite | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SUGP2 mRNA | CTD | PMID:38568856 | Sugp2 | Rat | tamoxifen | affects expression | ISO | Sugp2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of SUGP2 mRNA | CTD | PMID:17555576 | Sugp2 | Rat | temozolomide | increases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of SUGP2 mRNA | CTD | PMID:31758290 | Sugp2 | Rat | tert-butyl hydroperoxide | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in decreased expression of SUGP2 mRNA | CTD | PMID:15336504 | Sugp2 | Rat | testosterone enanthate | affects expression | ISO | SUGP2 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of SUGP2 mRNA | CTD | PMID:17440010 | Sugp2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SUGP2 mRNA | CTD | PMID:23411599 | Sugp2 | Rat | thiram | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Thiram results in decreased expression of SUGP2 mRNA | CTD | PMID:38568856 | Sugp2 | Rat | titanium dioxide | increases methylation | ISO | Sugp2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of SUGP2 promoter | CTD | PMID:35295148 | Sugp2 | Rat | titanium dioxide | decreases methylation | ISO | Sugp2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SUGP2 gene | CTD | PMID:35295148 | Sugp2 | Rat | trichostatin A | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of SUGP2 mRNA | CTD | PMID:26272509 | Sugp2 | Rat | trichostatin A | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SUGP2 mRNA | CTD | PMID:27188386 | Sugp2 | Rat | triptonide | increases expression | ISO | Sugp2 (Mus musculus) | 6480464 | triptonide results in increased expression of SUGP2 mRNA | CTD | PMID:33045310 | Sugp2 | Rat | triptonide | affects expression | ISO | Sugp2 (Mus musculus) | 6480464 | triptonide affects the expression of SUGP2 mRNA | CTD | PMID:33045310 | Sugp2 | Rat | troglitazone | decreases expression | ISO | Sugp2 (Mus musculus) | 6480464 | troglitazone results in decreased expression of SUGP2 mRNA | CTD | PMID:28973697 | Sugp2 | Rat | valproic acid | decreases methylation | ISO | SUGP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SUGP2 gene | CTD | PMID:29154799 | Sugp2 | Rat | valproic acid | increases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SUGP2 mRNA | CTD | PMID:23179753 | Sugp2 | Rat | valproic acid | decreases expression | ISO | SUGP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of SUGP2 mRNA | CTD | PMID:26272509 and PMID:28001369 | Sugp2 | Rat | valproic acid | multiple interactions | ISO | SUGP2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SUGP2 mRNA | CTD | PMID:27188386 | Sugp2 | Rat | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of SUGP2 mRNA | CTD | PMID:29427782 | |