Tnfaip8 (TNF alpha induced protein 8) - Rat Genome Database

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Gene: Tnfaip8 (TNF alpha induced protein 8) Rattus norvegicus
Analyze
Symbol: Tnfaip8
Name: TNF alpha induced protein 8
RGD ID: 1305908
Description: Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; molecular sequestering activity; and small molecule binding activity. Predicted to be involved in positive regulation of apoptotic process. Predicted to act upstream of or within defense response to Gram-positive bacterium. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human TNFAIP8 (TNF alpha induced protein 8); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC307428; tumor necrosis factor alpha-induced protein 8; tumor necrosis factor, alpha-induced protein 8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81845,370,334 - 45,486,036 (+)NCBIGRCr8
mRatBN7.21843,183,854 - 43,299,512 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1843,183,916 - 43,299,517 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1845,301,632 - 45,342,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01846,022,691 - 46,063,818 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01843,807,539 - 43,848,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01844,664,310 - 44,779,914 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1844,716,226 - 44,779,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01843,887,315 - 44,002,489 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41845,083,452 - 45,126,709 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11845,122,809 - 45,163,265 (+)NCBI
Celera1841,480,923 - 41,523,804 (+)NCBICelera
Cytogenetic Map18q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,6-dinitrotoluene  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxynon-2-enal  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpromazine  (EXP)
choline  (ISO)
chromium(6+)  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dieldrin  (EXP)
dioxygen  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fipronil  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gentamycin  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
ibuprofen  (ISO)
ifosfamide  (ISO)
indole-3-methanol  (EXP)
indometacin  (ISO)
inulin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
mercury atom  (EXP,ISO)
mercury(0)  (EXP,ISO)
metformin  (EXP)
methotrexate  (ISO)
methoxychlor  (EXP)
motexafin gadolinium  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodimethylamine  (EXP,ISO)
nickel dichloride  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
succimer  (ISO)
sunitinib  (ISO)
tetrachloromethane  (ISO)
theophylline  (ISO)
tolcapone  (EXP)
topotecan  (EXP,ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zinc acetate  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
nucleoplasm  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10644768   PMID:14724590   PMID:20699119   PMID:20824097   PMID:32414226  


Genomics

Comparative Map Data
Tnfaip8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81845,370,334 - 45,486,036 (+)NCBIGRCr8
mRatBN7.21843,183,854 - 43,299,512 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1843,183,916 - 43,299,517 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1845,301,632 - 45,342,848 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01846,022,691 - 46,063,818 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01843,807,539 - 43,848,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01844,664,310 - 44,779,914 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1844,716,226 - 44,779,914 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01843,887,315 - 44,002,489 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41845,083,452 - 45,126,709 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11845,122,809 - 45,163,265 (+)NCBI
Celera1841,480,923 - 41,523,804 (+)NCBICelera
Cytogenetic Map18q11NCBI
TNFAIP8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385119,268,759 - 119,399,688 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5119,268,692 - 119,399,688 (+)EnsemblGRCh38hg38GRCh38
GRCh375118,604,454 - 118,735,383 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365118,632,317 - 118,758,193 (+)NCBINCBI36Build 36hg18NCBI36
Build 345118,719,628 - 118,758,192NCBI
Celera5114,558,091 - 114,683,993 (+)NCBICelera
Cytogenetic Map5q23.1NCBI
HuRef5113,799,532 - 113,925,583 (+)NCBIHuRef
CHM1_15118,037,375 - 118,163,249 (+)NCBICHM1_1
T2T-CHM13v2.05119,789,607 - 119,920,525 (+)NCBIT2T-CHM13v2.0
Tnfaip8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391850,112,494 - 50,226,296 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1850,112,494 - 50,240,240 (+)EnsemblGRCm39 Ensembl
GRCm381849,979,427 - 50,093,229 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1849,979,427 - 50,107,173 (+)EnsemblGRCm38mm10GRCm38
MGSCv371850,139,081 - 50,252,883 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361850,178,850 - 50,217,109 (+)NCBIMGSCv36mm8
Celera1851,306,422 - 51,422,906 (+)NCBICelera
Cytogenetic Map18D1NCBI
cM Map1827.18NCBI
Tnfaip8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540838,872,007 - 38,990,650 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540838,872,305 - 38,986,932 (+)NCBIChiLan1.0ChiLan1.0
TNFAIP8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24114,545,300 - 114,673,060 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15112,698,975 - 112,826,728 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05114,657,140 - 114,784,819 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15120,442,285 - 120,569,877 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5120,442,500 - 120,569,877 (+)Ensemblpanpan1.1panPan2
TNFAIP8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1118,624,106 - 8,685,389 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl118,660,557 - 8,684,374 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha119,700,733 - 9,813,900 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0118,658,239 - 8,771,568 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl118,658,262 - 8,771,567 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1118,529,756 - 8,642,940 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0118,586,408 - 8,699,585 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0118,843,971 - 8,957,206 (+)NCBIUU_Cfam_GSD_1.0
Tnfaip8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213131,646,610 - 131,763,418 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367152,205,977 - 2,322,854 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367152,205,977 - 2,322,835 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNFAIP8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2123,152,371 - 123,287,941 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12123,152,349 - 123,285,154 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22128,681,402 - 128,723,913 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TNFAIP8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12322,514,427 - 22,636,888 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2322,573,208 - 22,636,936 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603455,673,230 - 55,795,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnfaip8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247332,271,825 - 2,396,307 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247332,272,634 - 2,397,002 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tnfaip8
435 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:465
Count of miRNA genes:244
Interacting mature miRNAs:302
Transcripts:ENSRNOT00000021972
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2299160Iddm35Insulin dependent diabetes mellitus QTL 352.79blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)18420794160377792Rat
2293708Bss46Bone structure and strength QTL 468.80.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)181179151863636873Rat
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
1331753Bp231Blood pressure QTL 2313.643arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194429952293055Rat
1358358Sradr6Stress Responsive Adrenal Weight QTL 62.49adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)181194429959330563Rat
6903359Bp355Blood pressure QTL 3553.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)181194454459796478Rat
2313082Bss85Bone structure and strength QTL 850.80.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)181495133759951337Rat
1358193Emca2Estrogen-induced mammary cancer QTL 21.6mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)181800759963571040Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
1641923Colcr8Colorectal carcinoma resistance QTL 83.10.0014intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)182206624252293055Rat
1331733Bp233Blood pressure QTL 2333.97196arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182479697779788953Rat
2325839Bp348Blood pressure QTL 3480.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182557098570570985Rat
12904673Cm127Cardiac mass QTL 1270.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)182654808246969551Rat
12904675Am19Aortic mass QTL 190.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)182654808246969551Rat
12904677Kidm72Kidney mass QTL 720.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)182654808246969551Rat
12904668Bw188Body weight QTL 1880.03body mass (VT:0001259)body weight (CMO:0000012)182654808246969551Rat
12904669Cm125Cardiac mass QTL 1250.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)182654808246969551Rat
12904670Cm126Cardiac mass QTL 1260.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)182654808246969551Rat
2301413Bp318Blood pressure QTL 3180.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182654808246969551Rat
2293704Bss35Bone structure and strength QTL 354.590.0002femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)182896485373964853Rat
2300157Bmd66Bone mineral density QTL 6613.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
2300177Bmd65Bone mineral density QTL 6519.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)182896485373964853Rat
9589816Gluco68Glucose level QTL 687.250.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)182979296574792965Rat
8694378Bw157Body weight QTL 1573.590.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)182979296574792965Rat
9590318Scort22Serum corticosterone level QTL 227.640.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)182979296574792965Rat
1331754Bp230Blood pressure QTL 2304.61609arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)182979296574792965Rat
738005Anxrr11Anxiety related response QTL 113.4exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)183003981375039813Rat
61383Bp47Blood pressure QTL 4717.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)183127168160377755Rat
1331742Bp228Blood pressure QTL 2283.88752arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331774Bp226Blood pressure QTL 2264.41065arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331776Bp225Blood pressure QTL 2252.829arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)183135940859796643Rat
1331798Bp224Blood pressure QTL 2243.53873arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940859796643Rat
1331727Bp237Blood pressure QTL 2373.053arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135940861698465Rat
61429Cia17Collagen induced arthritis QTL 174.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)183135940870263868Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
6903347Bp350Blood pressure QTL 3504.4arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)183135953059796478Rat
631274Sprol1Serum protein level QTL 15.3blood total protein amount (VT:0005567)serum total protein level (CMO:0000661)183139332077209694Rat
631518Bw11Body weight QTL 112.8body mass (VT:0001259)body weight (CMO:0000012)183587072380870723Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat

Markers in Region
RH129816  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21843,298,571 - 43,298,773 (+)MAPPERmRatBN7.2
Rnor_6.01844,778,969 - 44,779,170NCBIRnor6.0
Rnor_5.01844,001,544 - 44,001,745UniSTSRnor5.0
RGSC_v3.41845,125,760 - 45,125,965UniSTSRGSC3.4
Celera1841,522,859 - 41,523,060UniSTS
Cytogenetic Map18q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 25 24 16 19 16 19 35 29 11
Low 18 33 25 25 8 11 55 11 8
Below cutoff 1

Sequence


RefSeq Acc Id: ENSRNOT00000021972   ⟹   ENSRNOP00000021972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1843,256,748 - 43,299,517 (+)Ensembl
Rnor_6.0 Ensembl1844,737,154 - 44,779,914 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086431   ⟹   ENSRNOP00000072322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1843,224,521 - 43,299,333 (+)Ensembl
Rnor_6.0 Ensembl1844,716,226 - 44,779,903 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097607   ⟹   ENSRNOP00000095552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1843,234,186 - 43,299,333 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118975   ⟹   ENSRNOP00000076830
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1843,183,916 - 43,298,803 (+)Ensembl
RefSeq Acc Id: NM_001107387   ⟹   NP_001100857
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81845,444,966 - 45,486,036 (+)NCBI
mRatBN7.21843,258,433 - 43,299,512 (+)NCBI
Rnor_6.01844,737,154 - 44,779,914 (+)NCBI
Rnor_5.01843,887,315 - 44,002,489 (+)NCBI
RGSC_v3.41845,083,452 - 45,126,709 (+)RGD
Celera1841,480,923 - 41,523,804 (+)RGD
Sequence:
RefSeq Acc Id: XM_006254708   ⟹   XP_006254770
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81845,422,083 - 45,486,036 (+)NCBI
mRatBN7.21843,235,648 - 43,299,512 (+)NCBI
Rnor_6.01844,710,030 - 44,779,909 (+)NCBI
Rnor_5.01843,887,315 - 44,002,489 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006254709   ⟹   XP_006254771
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81845,370,334 - 45,486,036 (+)NCBI
mRatBN7.21843,183,859 - 43,299,512 (+)NCBI
Rnor_6.01844,664,310 - 44,779,909 (+)NCBI
Rnor_5.01843,887,315 - 44,002,489 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096838   ⟹   XP_038952766
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81845,411,074 - 45,486,036 (+)NCBI
mRatBN7.21843,224,585 - 43,299,512 (+)NCBI
RefSeq Acc Id: XM_063277358   ⟹   XP_063133428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81845,449,158 - 45,486,036 (+)NCBI
RefSeq Acc Id: NP_001100857   ⟸   NM_001107387
- UniProtKB: D4A9G3 (UniProtKB/TrEMBL),   A6IX01 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254771   ⟸   XM_006254709
- Peptide Label: isoform X3
- UniProtKB: A0A8I5Y0F2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254770   ⟸   XM_006254708
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AJX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021972   ⟸   ENSRNOT00000021972
RefSeq Acc Id: ENSRNOP00000072322   ⟸   ENSRNOT00000086431
RefSeq Acc Id: XP_038952766   ⟸   XM_039096838
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2P3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000095552   ⟸   ENSRNOT00000097607
RefSeq Acc Id: ENSRNOP00000076830   ⟸   ENSRNOT00000118975
RefSeq Acc Id: XP_063133428   ⟸   XM_063277358
- Peptide Label: isoform X4
- UniProtKB: A6IX03 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K2P3-F1-model_v2 AlphaFold A0A0G2K2P3 1-192 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700773
Promoter ID:EPDNEW_R11297
Type:initiation region
Name:Tnfaip8_1
Description:TNF alpha induced protein 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01844,738,897 - 44,738,957EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305908 AgrOrtholog
BioCyc Gene G2FUF-7551 BioCyc
Ensembl Genes ENSRNOG00000026136 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021972 ENTREZGENE
  ENSRNOT00000021972.6 UniProtKB/TrEMBL
  ENSRNOT00000086431.2 UniProtKB/TrEMBL
  ENSRNOT00000097607.1 UniProtKB/TrEMBL
  ENSRNOT00000118975.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1440.160 UniProtKB/TrEMBL
InterPro DUF758 UniProtKB/TrEMBL
  TNFAIP8_sf UniProtKB/TrEMBL
KEGG Report rno:307428 UniProtKB/TrEMBL
NCBI Gene 307428 ENTREZGENE
PANTHER DUF758 UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8 UniProtKB/TrEMBL
Pfam DUF758 UniProtKB/TrEMBL
PhenoGen Tnfaip8 PhenoGen
RatGTEx ENSRNOG00000026136 RatGTEx
UniProt A0A0G2K2P3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y0F2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AJX1 ENTREZGENE, UniProtKB/TrEMBL
  A6IX01 ENTREZGENE, UniProtKB/TrEMBL
  A6IX03 ENTREZGENE, UniProtKB/TrEMBL
  D4A9G3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-02 Tnfaip8  TNF alpha induced protein 8  Tnfaip8  tumor necrosis factor, alpha-induced protein 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Tnfaip8  tumor necrosis factor, alpha-induced protein 8   Tnfaip8_predicted  tumor necrosis factor, alpha-induced protein 8 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Tnfaip8_predicted  tumor necrosis factor, alpha-induced protein 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED