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Gene: Tnfaip8 (TNF alpha induced protein 8) Rattus norvegicus

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Symbol:

Tnfaip8

Name:

TNF alpha induced protein 8

RGD ID:

1305908

Description:

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process; molecular sequestering activity; and small molecule binding activity. Predicted to be involved in positive regulation of apoptotic process. Predicted to act upstream of or within defense response to Gram-positive bacterium. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human TNFAIP8 (TNF alpha induced protein 8); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC307428; tumor necrosis factor alpha-induced protein 8; tumor necrosis factor, alpha-induced protein 8

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TNFAIP8 (TNF alpha induced protein 8)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tnfaip8 (tumor necrosis factor, alpha-induced protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tnfaip8 (TNF alpha induced protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TNFAIP8 (TNF alpha induced protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TNFAIP8 (TNF alpha induced protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tnfaip8 (TNF alpha induced protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TNFAIP8 (TNF alpha induced protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TNFAIP8 (TNF alpha induced protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tnfaip8 (TNF alpha induced protein 8)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CEP15 (centrosomal protein 15)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	TNFAIP8 (TNF alpha induced protein 8)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tnfaip8 (tumor necrosis factor, alpha-induced protein 8)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tnfaip8l1 (tumor necrosis factor, alpha-induced protein 8-like 1)	Alliance	DIOPT (InParanoid\|OrthoInspector\|SonicParanoid)
Drosophila melanogaster (fruit fly):	sigmar	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tnfaip8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	45,370,334 - 45,486,036 (+)	NCBI		GRCr8
mRatBN7.2	18	43,183,854 - 43,299,512 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	43,183,916 - 43,299,517 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	45,301,632 - 45,342,848 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	46,022,691 - 46,063,818 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	43,807,539 - 43,848,751 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	44,664,310 - 44,779,914 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	44,716,226 - 44,779,914 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	43,887,315 - 44,002,489 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	45,083,452 - 45,126,709 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	45,122,809 - 45,163,265 (+)	NCBI
Celera	18	41,480,923 - 41,523,804 (+)	NCBI		Celera
Cytogenetic Map	18	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

esophagus squamous cell carcinoma (ISO)

Experimental Liver Cirrhosis (ISO)

familial adenomatous polyposis 1 (ISO)

Hereditary Neoplastic Syndromes (ISO)

juvenile rheumatoid arthritis (ISO)

Neoplasm Metastasis (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

17beta-estradiol (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3-dimethoxynaphthalene-1,4-dione (ISO)

2,6-dinitrotoluene (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpromazine (EXP)

choline (ISO)

chromium(6+) (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

clodronic acid (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

dieldrin (EXP)

dioxygen (ISO)

diuron (EXP)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fipronil (EXP)

folic acid (ISO)

fulvestrant (ISO)

genistein (ISO)

gentamycin (EXP)

hydralazine (ISO)

hydrogen peroxide (ISO)

ibuprofen (ISO)

ifosfamide (ISO)

indole-3-methanol (EXP)

indometacin (ISO)

inulin (ISO)

ivermectin (ISO)

L-methionine (ISO)

lipopolysaccharide (ISO)

mercury atom (EXP,ISO)

mercury(0) (EXP,ISO)

metformin (EXP)

methotrexate (ISO)

methoxychlor (EXP)

motexafin gadolinium (ISO)

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (ISO)

N,N-diethyl-m-toluamide (EXP)

N-nitrosodimethylamine (EXP,ISO)

nickel dichloride (ISO)

nitrates (ISO)

oxaliplatin (EXP)

ozone (ISO)

p-menthan-3-ol (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

permethrin (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

quercetin (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

Soman (EXP)

succimer (ISO)

sunitinib (ISO)

tetrachloromethane (ISO)

theophylline (ISO)

tolcapone (EXP)

topotecan (EXP,ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (ISO)

tris(2-butoxyethyl) phosphate (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

zinc acetate (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA)

defense response to Gram-positive bacterium (ISO)

positive regulation of apoptotic process (IEA,ISO)

regulation of apoptotic process (IEA)

Cellular Component

cytoplasm (IBA,IEA,ISO)

nucleoplasm (IEA,ISO)

Molecular Function

cysteine-type endopeptidase inhibitor activity involved in apoptotic process (IBA,IEA,ISO)

molecular sequestering activity (ISO)

protein binding (ISO)

small molecule binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10644768	PMID:14724590	PMID:20699119	PMID:20824097	PMID:32414226

Genomics

Comparative Map Data

Tnfaip8
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	45,370,334 - 45,486,036 (+)	NCBI		GRCr8
mRatBN7.2	18	43,183,854 - 43,299,512 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	43,183,916 - 43,299,517 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	45,301,632 - 45,342,848 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	46,022,691 - 46,063,818 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	43,807,539 - 43,848,751 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	44,664,310 - 44,779,914 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	44,716,226 - 44,779,914 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	43,887,315 - 44,002,489 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	45,083,452 - 45,126,709 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	45,122,809 - 45,163,265 (+)	NCBI
Celera	18	41,480,923 - 41,523,804 (+)	NCBI		Celera
Cytogenetic Map	18	q11	NCBI

TNFAIP8
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	119,268,759 - 119,399,688 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	119,268,692 - 119,399,688 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	118,604,454 - 118,735,383 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	118,632,317 - 118,758,193 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	118,719,628 - 118,758,192	NCBI
Celera	5	114,558,091 - 114,683,993 (+)	NCBI		Celera
Cytogenetic Map	5	q23.1	NCBI
HuRef	5	113,799,532 - 113,925,583 (+)	NCBI		HuRef
CHM1_1	5	118,037,375 - 118,163,249 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	119,789,607 - 119,920,525 (+)	NCBI		T2T-CHM13v2.0

Tnfaip8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	50,112,494 - 50,226,296 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	50,112,494 - 50,240,240 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	49,979,427 - 50,093,229 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	49,979,427 - 50,107,173 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	50,139,081 - 50,252,883 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	50,178,850 - 50,217,109 (+)	NCBI		MGSCv36	mm8
Celera	18	51,306,422 - 51,422,906 (+)	NCBI		Celera
Cytogenetic Map	18	D1	NCBI
cM Map	18	27.18	NCBI

Tnfaip8
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955408	38,872,007 - 38,990,650 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955408	38,872,305 - 38,986,932 (+)	NCBI	ChiLan1.0	ChiLan1.0

TNFAIP8
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	114,545,300 - 114,673,060 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	112,698,975 - 112,826,728 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	114,657,140 - 114,784,819 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	120,442,285 - 120,569,877 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	120,442,500 - 120,569,877 (+)	Ensembl	panpan1.1		panPan2

TNFAIP8
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	8,624,106 - 8,685,389 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	8,660,557 - 8,684,374 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	9,700,733 - 9,813,900 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	8,658,239 - 8,771,568 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	8,658,262 - 8,771,567 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	8,529,756 - 8,642,940 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	8,586,408 - 8,699,585 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	8,843,971 - 8,957,206 (+)	NCBI		UU_Cfam_GSD_1.0

Tnfaip8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	131,646,610 - 131,763,418 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936715	2,205,977 - 2,322,854 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936715	2,205,977 - 2,322,835 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TNFAIP8
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	123,152,371 - 123,287,941 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	123,152,349 - 123,285,154 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	128,681,402 - 128,723,913 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TNFAIP8
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	22,514,427 - 22,636,888 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	22,573,208 - 22,636,936 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	55,673,230 - 55,795,744 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tnfaip8
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624733	2,271,825 - 2,396,307 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624733	2,272,634 - 2,397,002 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tnfaip8
436 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	465
Count of miRNA genes:	244
Interacting mature miRNAs:	302
Transcripts:	ENSRNOT00000021972
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	24796977	79788953	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
1331798	Bp224	Blood pressure QTL 224	3.53873		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
2301413	Bp318	Blood pressure QTL 318		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	26548082	46969551	Rat
61383	Bp47	Blood pressure QTL 47	17.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	31271681	60377755	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
1331742	Bp228	Blood pressure QTL 228	3.88752		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
1331776	Bp225	Blood pressure QTL 225	2.829		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	31359408	59796643	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
631518	Bw11	Body weight QTL 11	2.8		body mass (VT:0001259)	body weight (CMO:0000012)	18	35870723	80870723	Rat
12904668	Bw188	Body weight QTL 188		0.03	body mass (VT:0001259)	body weight (CMO:0000012)	18	26548082	46969551	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	14951337	59951337	Rat
12904669	Cm125	Cardiac mass QTL 125		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	26548082	46969551	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	22066242	52293055	Rat
12904670	Cm126	Cardiac mass QTL 126		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	26548082	46969551	Rat
6903347	Bp350	Blood pressure QTL 350	4.4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359530	59796478	Rat
1331727	Bp237	Blood pressure QTL 237	3.053		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	61698465	Rat
2300157	Bmd66	Bone mineral density QTL 66	13.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
738005	Anxrr11	Anxiety related response QTL 11	3.4		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	18	30039813	75039813	Rat
12904677	Kidm72	Kidney mass QTL 72		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	26548082	46969551	Rat
631274	Sprol1	Serum protein level QTL 1	5.3		blood total protein amount (VT:0005567)	serum total protein level (CMO:0000661)	18	31393320	77209694	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	18007599	63571040	Rat
12904673	Cm127	Cardiac mass QTL 127		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	26548082	46969551	Rat
12904675	Am19	Aortic mass QTL 19		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	26548082	46969551	Rat
2293704	Bss35	Bone structure and strength QTL 35	4.59	0.0002	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	18	28964853	73964853	Rat
9589816	Gluco68	Glucose level QTL 68	7.25	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	29792965	74792965	Rat
1331774	Bp226	Blood pressure QTL 226	4.41065		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	31359408	59796643	Rat
2325839	Bp348	Blood pressure QTL 348		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	25570985	70570985	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
8694378	Bw157	Body weight QTL 157	3.59	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	18	29792965	74792965	Rat
2300177	Bmd65	Bone mineral density QTL 65	19.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	18	28964853	73964853	Rat
1598826	Anxrr20	Anxiety related response QTL 20	3.04		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	18	41432971	83828827	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
2303120	Mamtr8	Mammary tumor resistance QTL 8		0.001	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	18	31359408	83218561	Rat
61429	Cia17	Collagen induced arthritis QTL 17	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	18	31359408	70263868	Rat
61367	Iddm4	Insulin dependent diabetes mellitus QTL 4	2.33	0.0074	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	18	38192455	83192455	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
9590318	Scort22	Serum corticosterone level QTL 22	7.64	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	29792965	74792965	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944299	52293055	Rat
1331754	Bp230	Blood pressure QTL 230	4.61609		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	29792965	74792965	Rat

Markers in Region

RH129816

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	43,298,571 - 43,298,773 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	44,778,969 - 44,779,170	NCBI	Rnor6.0
Rnor_5.0	18	44,001,544 - 44,001,745	UniSTS	Rnor5.0
RGSC_v3.4	18	45,125,760 - 45,125,965	UniSTS	RGSC3.4
Celera	18	41,522,859 - 41,523,060	UniSTS
Cytogenetic Map	18	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107387	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254708	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006254709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039096838	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063277358	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473971	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ217459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ230976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ231450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235239	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021972 ⟹ ENSRNOP00000021972

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	43,256,748 - 43,299,517 (+)	Ensembl
Rnor_6.0 Ensembl	18	44,737,154 - 44,779,914 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086431 ⟹ ENSRNOP00000072322

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	43,224,521 - 43,299,333 (+)	Ensembl
Rnor_6.0 Ensembl	18	44,716,226 - 44,779,903 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097607 ⟹ ENSRNOP00000095552

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	43,234,186 - 43,299,333 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118975 ⟹ ENSRNOP00000076830

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	43,183,916 - 43,298,803 (+)	Ensembl

RefSeq Acc Id:

NM_001107387 ⟹ NP_001100857

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	45,444,966 - 45,486,036 (+)	NCBI
mRatBN7.2	18	43,258,433 - 43,299,512 (+)	NCBI
Rnor_6.0	18	44,737,154 - 44,779,914 (+)	NCBI
Rnor_5.0	18	43,887,315 - 44,002,489 (+)	NCBI
RGSC_v3.4	18	45,083,452 - 45,126,709 (+)	RGD
Celera	18	41,480,923 - 41,523,804 (+)	RGD

Sequence:

show sequence

TCCACAGAAGGTATCTCATTTGTGTAGCAAACAGCTGTGGCGAGCTTCCTCAGAGGCCCAGGTG
GACATCTATGGACATCTGGCCGGGAGAAGGGGAAGGGGGAAGGCAAAGCCAGATGCTGTAGGGA
GAATGTAACAATATCCAGCCAGATATTTCTTTCCATTGGGTGTTTTCCTTTCGGAGCACCTTTC
CTGCGCTGGGCCCCACCTGCCCGGTCGCCTCCACCCGTAGCGGCCCCTCGGGGGCGGACTCCTG
CAGCCCAGCCCCGTGCGATTCGTCACTCCTGCGGAACTTTCCCCTCAAAATCCCTCCCGCAGCC
AGACGCCCGCCCCGGGAGGTTCTGATCTCAGAGGCTTCCTCCCACCGCGTCCCGCCCGCGCACA
TCACACTGGTCTGGGAGCCTCGCAGCCTCACGTCCATGTCCGTGGCAGTGGTGCCTGCGGCTGT
GCACCCCGACAGCATGCTCTCCGAGGCGGAGGAGCCCAGGGAAGTGGCTACAGATGTCTTTAAT
TCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCCTGGGTAAAATGGTATCCAAATCCATCG
CCACCACCCTGATCGATGACACCAGCAGCGAGGTCCTGGATGAGCTGTACAGGGTGACCAAGGA
GTACACCCAGAACAAGAAGGAGGCAGAGAAGGTCATCAAGAACCTCATCAAGACGGTCATCAAG
CTGGCCGTTCTCCACAGGAACAATCAGTTCAACCAAGACGAGCTGGCCTTGATGGAGAAGTTCA
AGAGAAAGGTGCACCAGCTGGCCATGACGGTGGTGAGCTTTCACCAGGTAGAGTACACCTTTGA
CCGCAACGTGCTGTCCAGGCTGCTGAACGAGTGCCGAGAGCTCCTGCACGACATCATTCAGCGC
CACCTTACCGCCAAGTCTCACGGACGGGTTAATAACGTCTTTGATCATTTTTCAGATTGTGATT
TTTTGGCTGCCTTGTATAATCCCTTTGGAAAATTTAAACCTCACTTACAGAAACTTTGTGACGG
CATCAACAAAATGTTGGATGAAGAGAACATATGAGCTTGTGAGAGAAGACCGTGACCAGCAGCG
ATTTTTGTGACGTGGAGCACTGCTGACTCATAAAGGGAAGACAGAGAATCTTTTAGAGATCGCA
TGTTTTTCAGAAAGGCTTGGCCCCATACAGCCTGTTGTTGTTGGACATTCATAGTAGAACTCCT
GTGTGGCTTGTTGTATTTGAAAGAAAGAAAAAAAGCATATTGCTAAAAAATCTGGCTGAAAATA
CCTTAATGAATGGCAGGATGTGGGAAAAATGGATGGTTGGTCATTCAGATGTCTAGTGATACAA
AGACAGATGAGTGTGGCCCCAAGCGCTGGCACTTGCTGTGTTTTAGGGGAATCGTATTGGTGGC
ACATTGGATATTTCTAATATGTATTAAAGCTGTGTATCTTGACTCACCTTTATCCTTTGCTATG
TCTGCGTATCTCTCTTAAAATGCCAAGAACCTCTCTTTTGCTGTCATCGATCCTTTGGAAACAA
TTTTGCTTCTTTAGTTACAGGTTGTCATTGACCTTTAGGAATTAAATCTGAGGGGTTGGGGATT
TAGCTCAGTGGTAGAGCGCTCAAGGCCCTGGGTTCGGTCCCCAGCTCCGAAAAAAAGAAAAACA
AAAGGGAATTAAATCTGAGGCAGTCAAACCGAATGCTCAGGAAAGCAGAGACCTGCATCTGAAG
TCATGACCGTGGAAATGAGCAATCTTAACATCGTGAGTAACATCCACCGCAGCTTTTGAAGCTG
AGTCCTACTTTTTAGTACCATCAGTGAGACTTAGAGTCTCAAAACCAGTGGCATGGCATTGCCT
TGAAATACTTGCTTAGGGCCTAACTTTGATGTCATCTTGAACAGGTGCTCACATGTTCCCGTAT
TAACATCCATTTCACCCGTAGGAAGAATAAATTCCTAGATTGGCTTTGATATTGAGACAACAAC
ATGTAAGTAGCATTTCAGAAATAAAAAGAAAAACTTCTTGAGTTTAAAGATGAACTCATCAGGT
TGACTTAGGGGGGAAAGGATAGCAAGGATGTTGCGAAGTAATGTAAGAAAGATGCATGAATTTC
AGTGTGAATGGGGATTGATGAATAAAAGACGCCATTTTTTATTTAATGCCT

hide sequence

RefSeq Acc Id:

XM_006254708 ⟹ XP_006254770

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	45,422,083 - 45,486,036 (+)	NCBI
mRatBN7.2	18	43,235,648 - 43,299,512 (+)	NCBI
Rnor_6.0	18	44,710,030 - 44,779,909 (+)	NCBI
Rnor_5.0	18	43,887,315 - 44,002,489 (+)	NCBI

Sequence:

show sequence

ATAATTTTTAAAGGCCCAAAGGATATGATTGTATATATCATTAGCCTAGGCTCTTTCCTTTCTA
CAGACTCTAGACTGTTTCATACAATCCCTCTGCTTTACGTTCTTATGTGTGTATGTGTGTGGAC
ACATGTACGTGTGGACACATGTGTATGGCACATTTGGCAGCAAGCTCCTTTACAATGTGAACCT
TCTCACAGCCCTCGTGAGGGGTCTCCGTGTCCTTAACCACAGGTTTGTTTAAAGACTGTGTGGC
ATGGCAGTCTGTGGGGTTTCGTATGGTATTTAGAGAGTTGGGTCTGTCTTCTCCACCCAAACCC
ACTCCCCCACGCTCCCCTGGGTCACTTCATCTCATTTCAGTGGGTAGCTCAGGCTAGCCCTGAC
CTCTCTATCCAGCTGCCCCAGCCTCCCCAGCAATGCTGATAACCATGTTATCACACCAAGTAGC
TCTGCTCAGCTCTCATTGTTTGTCATAATCTATACAATTTCCTTAGATAATGGCTGTCTACATT
CTCCCCTGTTTCATTGACTGTGCTTGGACATGTTTCAGAGGGACTGTAGTTGTAAGACTTTTGA
TCTTTACTGCCACTTTGCCTTCCAGGCATTTGTCTTGTGTCACATTCCCACCAGATGATATATA
CATTTCTGACAATGTCTTAAACGAGCTGTGTATTCTAGCCCGTGCCTACCTCACAATTGCCTTT
CAGACCTTGCTTCTAACTGTGCATGCACAGGCTGCCCGGCCGTGCCTTCCTGACTCCATTGCCC
ACAGTAAGCCATGCATGCCCTGTCTCGGGCTATAGCCCAGTTCTTGGGGCTTCCAGACTGCTAG
TCCTTCGGTGTTGGGCATGCACCATCAATGCCCCAGCCATGGAGTGTTTCCATCCCCATTCCTT
CTTGCCTATGGCTCTATCTACATCTTTTACTTATGTGTATAGTCACTTCTTGGTCAGCCTCATT
GAGTGTCAGCTGATTCCTCATGGAGACCTCGTTTCTGAGTTAGCCTTGTAGTCAGCAAGTATCA
AGTGCCAGCCCTTTACTGTCAGCTGACATTTTTCAGATTAAACTGTCATATGTGCTCTCACTGG
CAGAAACAAGACAGGGGCTGATAGAATAGCACTGGACTTGGGGCTCCTGTGTCCTCCTGCTGTG
TAGGTCTGTATTAGTGGAAGAGAAGGGGCAATGCTAACCACTTTGCAGGGGATGAGGTACGGTC
TGCTTCCTTCTTCCATTAGAAAGGTATTTATTGGGGAGGAGGCAGTGGAGAACTTGTGTACAGC
ATGTAGGCTCTGCATACAGATGGACTCGGGTCCAAAATGGCTTGATATACCGTTCTCTCTGGCA
AGCACTAGAAAACAAGGTGCTTTTTTGAGTTTCTGTAATTTATTTTTATTATGTTTCTAAAATT
TGTGCTTGCAAACAGACCCATTGATATTACCACATAATGACCAAAGTGTTCTGACTGGAAATGC
TCTACTGGGATCTCTGGGATGTTGTGTCTTCACGAAACCACCTTTGACACCTTGTGGGAAATGT
TTACAGAAGCCAGTGGGGGCCGCACCAATGAGAACACAGCAGAAGCAGTGGCCAGCCAGACTGC
CAATGCAGGGGGCCAGGGCCTTGGAAAGTGTCTGATGTCAGATTGGAAAATATTCTGTGTTGCC
TCATTAAATAGAATTTCCAGAAATGTATAGGGAGATTTACTCCAAGACTGGATAGTTTCTCTTA
GCCAATTGAGAATTTAATTAGTTTAAGATTTATTACTGGGGTCCCCAACTCCAAAAAGAAGAAA
AAAAAAGATTTATTACTGGGGATCACGTTCTGTTTTGTGTGGCGTAAGAATGTTATAAAATCTA
GAGCCTCTGCTTCTGTTCATCTCGGCAGAGAATAAACCACATCCAGGTGCCAGCATAGCTGCTG
CAGCTGGAGCCTGGCACTTCAGCGTTTTCACTGGTGGCGCAAGCGTGACGAGGATTGGATTGGG
TATGAATGAATCGTACAAGAAAACAGACGTCCCTGGTCACTGAGTCCCCAGACCTGCTCACTGC
ATGGCCATGCTCCACTAGCACAGTGATGGGGCCTAGATGTCAACCTCCCATGCTGTCTCATCTT
CTTTGCTTGCGTGACATGGTTAGATGGTAGCAAGGCCCTTGGAAATACCAAAGTACAAGCTCCT
AAGAGGAAAACCGAAAGAATAACGTTTAATAAAATGCATACTTGAAACTGTAGCAGCGCGTAAA
CTCAGCGAGTAACACCTGATAGACAGGAGAGCATCAACCTTCCGAATGCTGCGAACCTTTCATG
CAGTCCCTCATCTTCGGTGACCCTCCAACCCTAAAATTATTTTTGTTGCTACTTCATAACTAAG
TTTGCTACTTTCATGAATCGTAACATAAATATCTGATATGCAGTCCTCCAAAGTGGTCGTGACC
CACAGATTGGGAGTCACGGTTTGAGCAGCTGCTTGGGCGGAGGGCTTTGAATGGCTCCAGTGAT
AGACTTGGGGAATCTCCACCCAACCTTGGTACTTGTGCCATTGCTGGTCCCAGCAGCATCTGTC
CAGTTTAGCTTGTTACTCTCCCTGGTCCCAGAGGGGTTGATGTCCAGGTGCCCTGTTTATTTTC
TCAGACTGCCCCCATTGTGCTGTGTGGTAAGCCAAGGACCTTTCTGTGGAGTTATCAGCCAATG
AATCTGAAAAGAGGCAAACCCGATACACCCGTGTATCACCACCCAACCCAGATGAGAGAGTTAG
ATGGCACTTAGATTCCTTGTCTGTAATCTGGAGATGTTGCCCACCTCCTGGGTAAGCATCATGC
TCTCACGGCGGGGCAGCGGGTGGCCATTCAGCTGTAGGCTTTCCCTAAGCATGACTAGGCTTGG
GCCCTGGGCTTCATGCTAAGCTAGGCCATCCGCCAGGTGCGTCCTCTTTGGTGGAGTATCTAGA
GTGCATCTCTGAGCATGTACCAGCTTCAGGCACTGCATCTCTTGGAACAATTCCATCAGGTCAC
CTTCACCAATGACTTCCTCCCTCTTGAAGAAGAGCAAAGTGAGAAGAGGAGAGAACTCTGGTTA
AATCGTGATTTGTAGTGGGCCATTGACAAAGCTAGGTAGGACTGGGAAAGAGGAGAGCTGGGAG
GAGACTGATGGACTAAGAGGAGGACGCTGAACACTAACACAGAAAATGAAGTTGATGTTGGCAG
TCTTAGCATTGTGCACAATGGGCCTGCGAGCCTCTTGGGAATAGCAGGCTATAAAGGTCAAGGT
GTTTTTGTGGATGTTTCCAGTTCCCTCTAAGGCTTGAAAACTCCTGTGTAATCCGTGAAGGCAT
CTTTTGCGTGCAGGCACCAGTGCGGTGGTGGTTGTTGAATGTGCTGCCGATAAGGATGTGGGTG
GTAGCACAGGAAGTTTCTGTATAATGCTCAACCACCAGAATGAGGCCAGAGTGAGAGTGTGTGT
CTGGAGATAGCTCTGGACGGTGGGAGGAATTGGTCTCAGGCGTTCTCTTCTCAGCCCTGCCCTG
TGCCCGCACAGCCTTGCTGCTACTTAGCCTCTTGCTCTGCTGTGTTCTTTGGAAATTGAAACTG
CCACCATTTTCCCTGGGTGTAGGGAGGATGTGGATTGCAGTGCCTGTTCCTGGCTATGAGTTGT
TAGTGAGCACAAAGTACAGCTGGTTTTCTAGTGGCCACTATCATGTGGCTGCAGAGAGATGCAG
AAACCTCTGATGGATGGCCCTGGAATCAAAGGGAGGGCCCTCAGTGTCAGCGTGTCACTCAGGG
CACCCGCATGACTGATGATGCAGGGTGCTCTTGGGGCTGGGGGGTTTGAACAGCCCTGTGCTTC
CACTGAGGTGTGCTCATCATATACAAGACTGACTTTGATCCTCAGTATTGCCAAAAAGATAAGA
TAGAGGTGCAACGAGTTGGGGGAGACTTGGAGAGCAAGAGTAAGGTGTATTTGAGTACAAATTT
TCTTCTCATTATCTAGTCTGGGCACATTCTTTGTCCAGGTTTGGAAATTCTGTGTGCTCCCCTC
TTGCCATGGCATGAGGAAGTATGTGCCCTGGACAGCACAACAAACACAGACTTGTGAATCCACC
CAGGGCTTGGGGCAGAGTGGAAGAGCTGTATCAATATCCCCAAGGGCAAAGGAGTTAACTATTT
TGTACATAGGTTACCCTGGGGGTGGGGAGGGGTTGGACCGCAGATCGTGACATGAGAATCTTCT
TCTTCCTCCCGATCAGCCCATCCTCTTTTAACCAGCTACATGAGTTGAGCAGAATATAATTCTG
GATGCTGGGACAGGTAAACAACAATGGACAGATCCAAGCATGTGTGACCCGGTGCTCAGATCTC
ATGTGAGAGAAGAGTGGAGTTTTCAAAGAAGGGTGCTGTCCATCCAGGTGTCTTGCTTTCCAGT
ATTTTCCCACTGTCTGGACTTCTCTGTGACCAGGGATATCCTGCTGCGTATGCTACCTGAGGGT
GTAATACTTCCAGCCTTCTCTTTCTGGCTCGGTGTTGGGAATTCCCTGGTGCTTTCTTCGCTGG
TCTTGGGTCCCACATAGGGGGTGAGTTTTGATGTGAGTTGCAGGAGTCTCACTCCAGCCTCCCC
TCTCCACAGCCTCACTGTGTACCTCTGTCTTCAGCAATCTGGAGAAAGCAGTGCCTAGTATCCA
CCTAGCCGTGAAACTACTCCTGAGTCCGTTTTAGGGATGCGGGAGATCTTCCCTTTGTTTAGGC
GTGGCTTTTTATTAATTACCCTAGAATATATCAGTAAACCAAGTTTGGGAAGTCCCTGGGCTTT
GGAATCTTGAATTTCTGAGAACAGATCTGTCTTAATATTTTCCTGTCACCAATGAAGCTTTCAT
ATCATTCTGGGCCAACCGGAGTTTGGAGAGATAACATTTTTGTGAGCACAGAAGGCGATTTCTA
AAACACAAATTTTGTAACTTCCTCCTATATGATTATATAGATAAAAAAATAAATGTACTTCTAT
GTTTATACATTGACGTTCATTCCCTTTCCTTTAGGTCACTCCCCCAATTAATAGAGGTCACTTT
ATTTAAATTTATGTCATCGGTTCCCATTACTGCTGGAATTCACTATGCATAAAGCAATTTGCAT
AGTTTTCTTTAAACTATGTTAACATTCTCTGAGTTTGACTGTGTTACTTTTAGTTTTGCAGAGG
TACAAACTTGTTCAGGGAGGTTAAAGAACTTGAGAGCCTACAAATCAGAAACTAGCAGAAATGG
AATTTGAATCAGGTCTAGCAAATTCTATTTCACTCTGTATCTTTTTTTTTTTTTGCTGGGTGCC
TGGCAACTCGAGCCAGATTATCAAAACCGCAAAAGATAAATGTAAAATCCAAAAGCAGCTTCCT
GGGGGAATAAGAGAGAAACACAAGCAAGGACGGTATTAACTGTAGTAACTATCACAAAATAGGG
CCAGGACATCGGAAAGTGTACAGCTGTAGGGTTAACGGAAGAGCTCGAGCTCACAGCCAAGGTC
ACCAGGAAAAGGCTTCATACCCTAATAGTGTGCTCCTCCGATGGGCAGAATCTTATCTGGGGGA
GGCTTGTAAGCCATGCTGACTTCTGAATATGCAGGTAAATAGATAAGACATTAAAGAGACTATC
AGATCGTCTCTATGGAGACATACATGCTGCATACATATGTGTGTGTATTTGTGTGTGCCCAAAC
ACTTCCATTCTTTATATGTCCCTCTCTTCACAAGCAAAAAGCTAATGATTTTAAGCAGTGACAT
TGTTCTAACCATGTTCCCTAGCTCTCCTAAGAACAAGAACACCTCTGAGCAATTCTTCCTATTA
ATAGACCTCCATTCATGTTTGTACTAGCTAGGTAGGAATGGGGTGTTGTTTTTTAAATTTTCCT
CTCCAGACATCTGTGAATGGAGCCACACCCTTTTGTCTTTTACTTTTTTTTTTTTAAGTCTCTG
CTTTTCCCCCCTAGCCTGTTGGAACAGTAGACTTCCTGTTTTGCTTGACTCTTTTTTTTTTTTA
AAAAAAAAACTTTTGCCAGTGTGCCTAGCACAGTAAGCTTGTTTCTGCGTAGCATCGCTCGCAG
GTACGGAGTGCGGGCAGTCACAATCCATCCTCGGTGTGAGTGCTGAGACCTCTGTGACAACACA
AGTAAAAGGTGCCTAACACATTCCTCTACCAACTGCAAAATGCAGCACCCCGAATAACAAGCAG
GACAGCTTCCAAAGTGACCACTGTTGACCAGTTTCCGGTGTGTTCTTCCGTGTGGTAAGCTTGT
GGTGGATTTCTTGGAAGGATGGTGTGAACTGACTTGTAAGATGGGACTGTGGATGTTCCTCATC
CTTGTGTGACTCTATCCAGACACATTGACGTTGTCCTCCTGGAGAGCACAGGGAGAAAATGCCG
AAACTGGTGGCTACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAGAAGATCC
TGGGTAAAATGGTATCCAAATCCATCGCCACCACCCTGATCGATGACACCAGCAGCGAGGTCCT
GGATGAGCTGTACAGGGTGACCAAGGAGTACACCCAGAACAAGAAGGAGGCAGAGAAGGTCATC
AAGAACCTCATCAAGACGGTCATCAAGCTGGCCGTTCTCCACAGGAACAATCAGTTCAACCAAG
ACGAGCTGGCCTTGATGGAGAAGTTCAAGAGAAAGGTGCACCAGCTGGCCATGACGGTGGTGAG
CTTTCACCAGGTAGAGTACACCTTTGACCGCAACGTGCTGTCCAGGCTGCTGAACGAGTGCCGA
GAGCTCCTGCACGACATCATTCAGCGCCACCTTACCGCCAAGTCTCACGGACGGGTTAATAACG
TCTTTGATCATTTTTCAGATTGTGATTTTTTGGCTGCCTTGTATAATCCCTTTGGAAAATTTAA
ACCTCACTTACAGAAACTTTGTGACGGCATCAACAAAATGTTGGATGAAGAGAACATATGAGCT
TGTGAGAGAAGACCGTGACCAGCAGCGATTTTTGTGACGTGGAGCACTGCTGACTCATAAAGGG
AAGACAGAGAATCTTTTAGAGATCGCATGTTTTTCAGAAAGGCTTGGCCCCATACAGCCTGTTG
TTGTTGGACATTCATAGTAGAACTCCTGTGTGGCTTGTTGTATTTGAAAGAAAGAAAAAAAGCA
TATTGCTAAAAAATCTGGCTGAAAATACCTTAATGAATGGCAGGATGTGGGAAAAATGGATGGT
TGGTCATTCAGATGTCTAGTGATACAAAGACAGATGAGTGTGGCCCCAAGCGCTGGCACTTGCT
GTGTTTTAGGGGAATCGTATTGGTGGCACATTGGATATTTCTAATATGTATTAAAGCTGTGTAT
CTTGACTCACCTTTATCCTTTGCTATGTCTGCGTATCTCTCTTAAAATGCCAAGAACCTCTCTT
TTGCTGTCATCGATCCTTTGGAAACAATTTTGCTTCTTTAGTTACAGGTTGTCATTGACCTTTA
GGAATTAAATCTGAGGGGTTGGGGATTTAGCTCAGTGGTAGAGCGCTCAAGGCCCTGGGTTCGG
TCCCCAGCTCCGAAAAAAAGAAAAACAAAAGGGAATTAAATCTGAGGCAGTCAAACCGAATGCT
CAGGAAAGCAGAGACCTGCATCTGAAGTCATGACCGTGGAAATGAGCAATCTTAACATCGTGAG
TAACATCCACCGCAGCTTTTGAAGCTGAGTCCTACTTTTTAGTACCATCAGTGAGACTTAGAGT
CTCAAAACCAGTGGCATGGCATTGCCTTGAAATACTTGCTTAGGGCCTAACTTTGATGTCATCT
TGAACAGGTGCTCACATGTTCCCGTATTAACATCCATTTCACCCGTAGGAAGAATAAATTCCTA
GATTGGCTTTGATATTGAGACAACAACATGTAAGTAGCATTTCAGAAATAAAAAGAAAAACTTC
TTGAGTTTAAAGATGAACTCATCAGGTTGACTTAGGGGGGAAAGGATAGCAAGGATGTTGCGAA
GTAATGTAAGAAAGATGCATGAATTTCAGTGTGAATGGGGATTGATGAATAAAAGACGCCATTT
TTTATTTAA

hide sequence

RefSeq Acc Id:

XM_006254709 ⟹ XP_006254771

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	45,370,334 - 45,486,036 (+)	NCBI
mRatBN7.2	18	43,183,859 - 43,299,512 (+)	NCBI
Rnor_6.0	18	44,664,310 - 44,779,909 (+)	NCBI
Rnor_5.0	18	43,887,315 - 44,002,489 (+)	NCBI

Sequence:

show sequence

GCTCGAGCTCCACTTCTCCCGCGCTGGGGCCCGCCTGGGGTTTTAGGGGGCCGAGAGCCGCGAG
TGGTCCAGCTCCGAGGAACAGCATTGCGGGACCGCCCCGTTCTTCACTCGTCCCGGCGCCGCCG
CGCCCTTCCTCCGATGGCTACAGATGTCTTTAATTCCAAAAACCTGGCCGTTCAGGCACAAAAG
AAGATCCTGGGTAAAATGGTATCCAAATCCATCGCCACCACCCTGATCGATGACACCAGCAGCG
AGGTCCTGGATGAGCTGTACAGGGTGACCAAGGAGTACACCCAGAACAAGAAGGAGGCAGAGAA
GGTCATCAAGAACCTCATCAAGACGGTCATCAAGCTGGCCGTTCTCCACAGGAACAATCAGTTC
AACCAAGACGAGCTGGCCTTGATGGAGAAGTTCAAGAGAAAGGTGCACCAGCTGGCCATGACGG
TGGTGAGCTTTCACCAGGTAGAGTACACCTTTGACCGCAACGTGCTGTCCAGGCTGCTGAACGA
GTGCCGAGAGCTCCTGCACGACATCATTCAGCGCCACCTTACCGCCAAGTCTCACGGACGGGTT
AATAACGTCTTTGATCATTTTTCAGATTGTGATTTTTTGGCTGCCTTGTATAATCCCTTTGGAA
AATTTAAACCTCACTTACAGAAACTTTGTGACGGCATCAACAAAATGTTGGATGAAGAGAACAT
ATGAGCTTGTGAGAGAAGACCGTGACCAGCAGCGATTTTTGTGACGTGGAGCACTGCTGACTCA
TAAAGGGAAGACAGAGAATCTTTTAGAGATCGCATGTTTTTCAGAAAGGCTTGGCCCCATACAG
CCTGTTGTTGTTGGACATTCATAGTAGAACTCCTGTGTGGCTTGTTGTATTTGAAAGAAAGAAA
AAAAGCATATTGCTAAAAAATCTGGCTGAAAATACCTTAATGAATGGCAGGATGTGGGAAAAAT
GGATGGTTGGTCATTCAGATGTCTAGTGATACAAAGACAGATGAGTGTGGCCCCAAGCGCTGGC
ACTTGCTGTGTTTTAGGGGAATCGTATTGGTGGCACATTGGATATTTCTAATATGTATTAAAGC
TGTGTATCTTGACTCACCTTTATCCTTTGCTATGTCTGCGTATCTCTCTTAAAATGCCAAGAAC
CTCTCTTTTGCTGTCATCGATCCTTTGGAAACAATTTTGCTTCTTTAGTTACAGGTTGTCATTG
ACCTTTAGGAATTAAATCTGAGGGGTTGGGGATTTAGCTCAGTGGTAGAGCGCTCAAGGCCCTG
GGTTCGGTCCCCAGCTCCGAAAAAAAGAAAAACAAAAGGGAATTAAATCTGAGGCAGTCAAACC
GAATGCTCAGGAAAGCAGAGACCTGCATCTGAAGTCATGACCGTGGAAATGAGCAATCTTAACA
TCGTGAGTAACATCCACCGCAGCTTTTGAAGCTGAGTCCTACTTTTTAGTACCATCAGTGAGAC
TTAGAGTCTCAAAACCAGTGGCATGGCATTGCCTTGAAATACTTGCTTAGGGCCTAACTTTGAT
GTCATCTTGAACAGGTGCTCACATGTTCCCGTATTAACATCCATTTCACCCGTAGGAAGAATAA
ATTCCTAGATTGGCTTTGATATTGAGACAACAACATGTAAGTAGCATTTCAGAAATAAAAAGAA
AAACTTCTTGAGTTTAAAGATGAACTCATCAGGTTGACTTAGGGGGGAAAGGATAGCAAGGATG
TTGCGAAGTAATGTAAGAAAGATGCATGAATTTCAGTGTGAATGGGGATTGATGAATAAAAGAC
GCCATTTTTTATTTAA

hide sequence

RefSeq Acc Id:

XM_039096838 ⟹ XP_038952766

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	45,411,074 - 45,486,036 (+)	NCBI
mRatBN7.2	18	43,224,585 - 43,299,512 (+)	NCBI

RefSeq Acc Id:

XM_063277358 ⟹ XP_063133428

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	18	45,449,158 - 45,486,036 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001100857	(Get FASTA)	NCBI Sequence Viewer
	XP_006254770	(Get FASTA)	NCBI Sequence Viewer
	XP_006254771	(Get FASTA)	NCBI Sequence Viewer
	XP_038952766	(Get FASTA)	NCBI Sequence Viewer
	XP_063133428	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM14432	(Get FASTA)	NCBI Sequence Viewer
	EDM14433	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021972
	ENSRNOP00000021972.4
	ENSRNOP00000072322
	ENSRNOP00000072322.2
	ENSRNOP00000076830
	ENSRNOP00000076830.1
	ENSRNOP00000095552.1
	ENSRNOP00000108196

RefSeq Acc Id:	NP_001100857 ⟸ NM_001107387
- UniProtKB:	D4A9G3 (UniProtKB/TrEMBL), A6IX01 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKNLIKTVIKLAVLHRNNQFNQDEL ALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECRELLHDIIQRHLTAKSHGRVNNVFD HFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI hide sequence

RefSeq Acc Id:	XP_006254771 ⟸ XM_006254709
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I5Y0F2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEKVIKN LIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNECREL LHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI hide sequence

RefSeq Acc Id:	XP_006254770 ⟸ XM_006254708
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6AJX1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MPKLVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTKEYTQNKKEAEK VIKNLIKTVIKLAVLHRNNQFNQDELALMEKFKRKVHQLAMTVVSFHQVEYTFDRNVLSRLLNE CRELLHDIIQRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGKFKPHLQKLCDGINKMLDEENI hide sequence

Ensembl Acc Id:

ENSRNOP00000021972 ⟸ ENSRNOT00000021972

Ensembl Acc Id:

ENSRNOP00000072322 ⟸ ENSRNOT00000086431

RefSeq Acc Id:	XP_038952766 ⟸ XM_039096838
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K2P3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000095552 ⟸ ENSRNOT00000097607

Ensembl Acc Id:

ENSRNOP00000076830 ⟸ ENSRNOT00000118975

RefSeq Acc Id:	XP_063133428 ⟸ XM_063277358
- Peptide Label:	isoform X4
- UniProtKB:	A6IX03 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K2P3-F1-model_v2	AlphaFold	A0A0G2K2P3	1-192	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700773

Promoter ID:

EPDNEW_R11297

Type:

initiation region

Name:

Tnfaip8_1

Description:

TNF alpha induced protein 8

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	18	44,738,897 - 44,738,957	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305908	AgrOrtholog
BioCyc Gene	G2FUF-7551	BioCyc
Ensembl Genes	ENSRNOG00000026136	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021972	ENTREZGENE
	ENSRNOT00000021972.6	UniProtKB/TrEMBL
	ENSRNOT00000086431	ENTREZGENE
	ENSRNOT00000086431.2	UniProtKB/TrEMBL
	ENSRNOT00000097607.1	UniProtKB/TrEMBL
	ENSRNOT00000118975	ENTREZGENE
	ENSRNOT00000118975.1	UniProtKB/TrEMBL
	ENSRNOT00000140138	ENTREZGENE
Gene3D-CATH	1.20.1440.160	UniProtKB/TrEMBL
InterPro	DUF758	UniProtKB/TrEMBL
	TNFAIP8_sf	UniProtKB/TrEMBL
KEGG Report	rno:307428	UniProtKB/TrEMBL
NCBI Gene	307428	ENTREZGENE
PANTHER	DUF758	UniProtKB/TrEMBL
	TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8	UniProtKB/TrEMBL
Pfam	DUF758	UniProtKB/TrEMBL
PhenoGen	Tnfaip8	PhenoGen
RatGTEx	ENSRNOG00000026136	RatGTEx
UniProt	A0A0G2K2P3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5Y0F2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AJX1	ENTREZGENE, UniProtKB/TrEMBL
	A6IX01	ENTREZGENE, UniProtKB/TrEMBL
	A6IX03	ENTREZGENE, UniProtKB/TrEMBL
	D4A9G3	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-02	Tnfaip8	TNF alpha induced protein 8	Tnfaip8	tumor necrosis factor, alpha-induced protein 8	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Tnfaip8	tumor necrosis factor, alpha-induced protein 8	Tnfaip8_predicted	tumor necrosis factor, alpha-induced protein 8 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Tnfaip8_predicted	tumor necrosis factor, alpha-induced protein 8 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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