Anks3 (ankyrin repeat and sterile alpha motif domain containing 3) - Rat Genome Database

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Gene: Anks3 (ankyrin repeat and sterile alpha motif domain containing 3) Rattus norvegicus
Analyze
Symbol: Anks3
Name: ankyrin repeat and sterile alpha motif domain containing 3
RGD ID: 1305833
Description: Predicted to localize to cilium and cytoplasm. Orthologous to human ANKS3 (ankyrin repeat and sterile alpha motif domain containing 3); INTERACTS WITH amphetamine; bisphenol A; vinclozolin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ankyrin repeat and SAM domain-containing protein 3; LOC302937; MGC94228; RGD1305833; similar to RIKEN cDNA 2700067D09
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21010,614,953 - 10,635,815 (+)NCBI
Rnor_6.0 Ensembl1010,808,823 - 10,831,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01010,808,780 - 10,829,507 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0109,575,611 - 9,596,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41010,732,109 - 10,752,778 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11010,732,108 - 10,752,776 (+)NCBI
Celera109,579,341 - 9,600,010 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cilium  (ISO)
cytoplasm  (ISO,ISS)

Molecular Function

References

References - curated
1. MGD data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:26188091   PMID:26327442   PMID:29395339  


Genomics

Comparative Map Data
Anks3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21010,614,953 - 10,635,815 (+)NCBI
Rnor_6.0 Ensembl1010,808,823 - 10,831,535 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01010,808,780 - 10,829,507 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0109,575,611 - 9,596,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41010,732,109 - 10,752,778 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11010,732,108 - 10,752,776 (+)NCBI
Celera109,579,341 - 9,600,010 (+)NCBICelera
Cytogenetic Map10q12NCBI
ANKS3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl164,696,510 - 4,734,378 (-)EnsemblGRCh38hg38GRCh38
GRCh38164,696,510 - 4,734,347 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37164,746,512 - 4,784,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,686,514 - 4,724,164 (-)NCBINCBI36hg18NCBI36
Celera164,955,291 - 4,992,944 (-)NCBI
Cytogenetic Map16p13.3NCBI
HuRef164,713,030 - 4,750,906 (-)NCBIHuRef
CHM1_1164,747,292 - 4,785,140 (-)NCBICHM1_1
Anks3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,759,279 - 4,783,362 (-)NCBIGRCm39mm39
GRCm39 Ensembl164,759,300 - 4,782,069 (-)Ensembl
GRCm38164,941,415 - 4,965,537 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,941,436 - 4,964,205 (-)EnsemblGRCm38mm10GRCm38
MGSCv37164,941,420 - 4,964,330 (-)NCBIGRCm37mm9NCBIm37
MGSCv36164,856,671 - 4,879,505 (-)NCBImm8
Celera165,572,755 - 5,595,570 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.48NCBI
Anks3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544212,752,008 - 12,775,081 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544212,752,468 - 12,775,081 (+)NCBIChiLan1.0ChiLan1.0
ANKS3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1164,788,093 - 4,822,178 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,788,093 - 4,820,760 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0163,621,185 - 3,659,570 (-)NCBIMhudiblu_PPA_v0panPan3
ANKS3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1636,678,916 - 36,711,096 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl636,669,590 - 36,710,807 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0636,882,187 - 36,914,161 (+)NCBI
UMICH_Zoey_3.1636,676,333 - 36,708,012 (+)NCBI
UNSW_CanFamBas_1.0636,569,127 - 36,600,861 (+)NCBI
UU_Cfam_GSD_1.0636,971,269 - 37,003,540 (+)NCBI
Anks3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,852,793 - 106,878,146 (-)NCBI
SpeTri2.0NW_0049365304,698,234 - 4,723,131 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANKS3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl337,639,811 - 37,689,501 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1337,664,182 - 37,689,502 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2338,725,118 - 38,748,113 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ANKS3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,378,318 - 4,413,266 (-)NCBI
ChlSab1.1 Ensembl54,375,517 - 4,413,199 (-)Ensembl
Anks3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248242,478,608 - 2,507,287 (-)NCBI

Position Markers
BM384744  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21010,632,503 - 10,632,688 (+)MAPPER
Rnor_6.01010,826,196 - 10,826,380NCBIRnor6.0
Rnor_5.0109,593,126 - 9,593,310UniSTSRnor5.0
RGSC_v3.41010,749,482 - 10,749,666UniSTSRGSC3.4
Celera109,596,714 - 9,596,898UniSTS
RH 3.4 Map10100.23UniSTS
Cytogenetic Map10q12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129592136Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135538813Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138594330Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142669970Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)10144902893Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1076442166221621Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10483563820170031Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10521719917555534Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10521719919591669Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)10546011921524070Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10546011921524070Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10546011921524070Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10546011921524070Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10546011921524070Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10587753664401490Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10622909575983805Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10622928936185929Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10642907599492409Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10752145052521450Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109841807108540162Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:247
Count of miRNA genes:149
Interacting mature miRNAs:165
Transcripts:ENSRNOT00000004298
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 2 10 2 16 2 69 32 35 11
Low 2 41 47 39 3 39 8 11 5 3 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001009676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006245790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008767484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597212 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005489786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005489787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005489788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC123492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC087062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000004298   ⟹   ENSRNOP00000004298
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1010,808,823 - 10,829,490 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000077347   ⟹   ENSRNOP00000070091
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1010,811,937 - 10,831,535 (+)Ensembl
RefSeq Acc Id: NM_001009676   ⟹   NP_001009676
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,615,129 - 10,635,800 (+)NCBI
Rnor_6.01010,808,823 - 10,829,492 (+)NCBI
Rnor_5.0109,575,611 - 9,596,437 (+)NCBI
RGSC_v3.41010,732,109 - 10,752,778 (+)RGD
Celera109,579,341 - 9,600,010 (+)RGD
Sequence:
RefSeq Acc Id: XM_006245788   ⟹   XP_006245850
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,615,050 - 10,635,815 (+)NCBI
Rnor_6.01010,808,780 - 10,829,507 (+)NCBI
Rnor_5.0109,575,611 - 9,596,437 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245789   ⟹   XP_006245851
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,615,050 - 10,635,815 (+)NCBI
Rnor_6.01010,808,780 - 10,829,507 (+)NCBI
Rnor_5.0109,575,611 - 9,596,437 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006245790   ⟹   XP_006245852
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,618,276 - 10,635,815 (+)NCBI
Rnor_6.01010,812,018 - 10,829,507 (+)NCBI
Rnor_5.0109,575,611 - 9,596,437 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008767483   ⟹   XP_008765705
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01010,812,015 - 10,829,507 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008767484   ⟹   XP_008765706
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,618,276 - 10,635,815 (+)NCBI
Rnor_6.01010,812,018 - 10,829,507 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597212   ⟹   XP_017452701
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01010,808,787 - 10,829,507 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039085839   ⟹   XP_038941767
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,615,050 - 10,635,815 (+)NCBI
RefSeq Acc Id: XM_039085840   ⟹   XP_038941768
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,615,050 - 10,635,383 (+)NCBI
RefSeq Acc Id: XM_039085842   ⟹   XP_038941770
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,614,953 - 10,635,815 (+)NCBI
RefSeq Acc Id: XM_039085843   ⟹   XP_038941771
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,621,226 - 10,635,815 (+)NCBI
RefSeq Acc Id: XR_005489786
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,615,050 - 10,635,815 (+)NCBI
RefSeq Acc Id: XR_005489787
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,615,050 - 10,635,487 (+)NCBI
RefSeq Acc Id: XR_005489788
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21010,615,050 - 10,634,969 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001009676   ⟸   NM_001009676
- UniProtKB: Q5M9H0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006245850   ⟸   XM_006245788
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006245851   ⟸   XM_006245789
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JX10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245852   ⟸   XM_006245790
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008765706   ⟸   XM_008767484
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_008765705   ⟸   XM_008767483
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017452701   ⟸   XM_017597212
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000004298   ⟸   ENSRNOT00000004298
RefSeq Acc Id: ENSRNOP00000070091   ⟸   ENSRNOT00000077347
RefSeq Acc Id: XP_038941770   ⟸   XM_039085842
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038941767   ⟸   XM_039085839
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038941768   ⟸   XM_039085840
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038941771   ⟸   XM_039085843
- Peptide Label: isoform X8
Protein Domains
ANK_REP_REGION   SAM

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696968
Promoter ID:EPDNEW_R7493
Type:multiple initiation site
Name:Anks3_1
Description:ankyrin repeat and sterile alpha motif domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01010,808,801 - 10,808,861EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305833 AgrOrtholog
Ensembl Genes ENSRNOG00000003186 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000004298 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000070091 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004298 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000077347 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131099 IMAGE-MGC_LOAD
InterPro Ankyrin_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:302937 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94228 IMAGE-MGC_LOAD
NCBI Gene 302937 ENTREZGENE
Pfam Ank_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Anks3 PhenoGen
PRINTS ANKYRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ANK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47769 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48403 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JX10 ENTREZGENE, UniProtKB/TrEMBL
  ANKS3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-07 Anks3  ankyrin repeat and sterile alpha motif domain containing 3  RGD1305833  similar to RIKEN cDNA 2700067D09  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1305833  similar to RIKEN cDNA 2700067D09  RGD1305833_predicted  similar to RIKEN cDNA 2700067D09 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1305833_predicted  similar to RIKEN cDNA 2700067D09 (predicted)  LOC302937_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC302937_predicted  similar to RIKEN cDNA 2700067D09 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL