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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Ttc39b | Rat | (-)-epigallocatechin 3-gallate | decreases expression | ISO | Ttc39b (Mus musculus) | 401827839 | (-)-epigallocatechin 3-gallate decreases expression of Ttc39b mRNA and protein in liver | RGD | | Ttc39b | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Ttc39b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TTC39B mRNA | CTD | PMID:22206623 | Ttc39b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TTC39B mRNA | CTD | PMID:20106945 and PMID:21632981 | Ttc39b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TTC39B mRNA | CTD | PMID:33387578 | Ttc39b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | TTC39B (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TTC39B mRNA | CTD | PMID:22574217 | Ttc39b | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:26705709 | Ttc39b | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TTC39B mRNA | CTD | PMID:30851411 | Ttc39b | Rat | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | Ttc39b (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:19467301 | Ttc39b | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Ttc39b (Mus musculus) | 6480464 | bisphenol S results in decreased expression of TTC39B mRNA | CTD | PMID:39298647 | Ttc39b | Rat | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of TTC39B mRNA | CTD | PMID:31881176 | Ttc39b | Rat | aconitine | decreases expression | EXP | | 6480464 | Aconitine results in decreased expression of TTC39B protein | CTD | PMID:33236894 | Ttc39b | Rat | aflatoxin B1 | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of TTC39B mRNA | CTD | PMID:19770486 | Ttc39b | Rat | aflatoxin B1 | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of TTC39B mRNA | CTD | PMID:27153756 | Ttc39b | Rat | aflatoxin B1 | decreases methylation | ISO | TTC39B (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TTC39B gene | CTD | PMID:27153756 | Ttc39b | Rat | antirheumatic drug | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TTC39B mRNA | CTD | PMID:24449571 | Ttc39b | Rat | aristolochic acid A | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TTC39B mRNA | CTD | PMID:33212167 | Ttc39b | Rat | Aroclor 1254 | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of TTC39B mRNA | CTD | PMID:25270620 | Ttc39b | Rat | arsane | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TTC39B mRNA | CTD | PMID:32525701 | Ttc39b | Rat | arsenic atom | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TTC39B mRNA | CTD | PMID:32525701 | Ttc39b | Rat | benzo[a]pyrene | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TTC39B mRNA | CTD | PMID:20064835 | Ttc39b | Rat | benzo[a]pyrene | increases methylation | ISO | TTC39B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TTC39B promoter | CTD | PMID:27901495 | Ttc39b | Rat | benzo[a]pyrene | decreases methylation | ISO | Ttc39b (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of TTC39B intron | CTD | PMID:27901495 | Ttc39b | Rat | benzo[a]pyrene | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TTC39B mRNA | CTD | PMID:19770486 | Ttc39b | Rat | benzoates | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Benzoates analog results in increased expression of TTC39B mRNA | CTD | PMID:29472718 | Ttc39b | Rat | beta-hexachlorocyclohexane | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | beta-hexachlorocyclohexane results in increased expression of TTC39B mRNA | CTD | PMID:25270620 | Ttc39b | Rat | bisphenol A | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | bisphenol A results in increased expression of TTC39B mRNA | CTD | PMID:26063408 | Ttc39b | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TTC39B mRNA | CTD | PMID:25181051 | Ttc39b | Rat | cadmium atom | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TTC39B mRNA | CTD | PMID:35301059 | Ttc39b | Rat | cadmium dichloride | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TTC39B mRNA | CTD | PMID:35301059 | Ttc39b | Rat | carbon nanotube | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | Ttc39b | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of TTC39B mRNA | CTD | PMID:24386269 | Ttc39b | Rat | copper(II) sulfate | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of TTC39B mRNA | CTD | PMID:19549813 | Ttc39b | Rat | coumestrol | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of TTC39B mRNA | CTD | PMID:19167446 | Ttc39b | Rat | coumestrol | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TTC39B mRNA | CTD | PMID:19167446 | Ttc39b | Rat | cyclosporin A | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TTC39B mRNA | CTD | PMID:20106945 more ... | Ttc39b | Rat | dicrotophos | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of TTC39B mRNA | CTD | PMID:28302478 | Ttc39b | Rat | dioxygen | multiple interactions | ISO | Ttc39b (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of TTC39B mRNA | CTD | PMID:30529165 | Ttc39b | Rat | disodium selenite | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of TTC39B mRNA | CTD | PMID:18175754 | Ttc39b | Rat | dorsomorphin | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TTC39B mRNA | CTD | PMID:27188386 | Ttc39b | Rat | doxorubicin | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TTC39B mRNA | CTD | PMID:29803840 | Ttc39b | Rat | Enterolactone | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TTC39B mRNA | CTD | PMID:19167446 | Ttc39b | Rat | entinostat | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | entinostat results in increased expression of TTC39B mRNA | CTD | PMID:26272509 | Ttc39b | Rat | entinostat | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TTC39B mRNA | CTD | PMID:27188386 | Ttc39b | Rat | fenthion | decreases expression | ISO | Ttc39b (Mus musculus) | 6480464 | Fenthion results in decreased expression of TTC39B mRNA | CTD | PMID:34813904 | Ttc39b | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of TTC39B mRNA | CTD | PMID:30307764 | Ttc39b | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of TTC39B mRNA | CTD | PMID:24136188 | Ttc39b | Rat | genistein | increases methylation | EXP | | 6480464 | Genistein results in increased methylation of TTC39B gene | CTD | PMID:28505145 | Ttc39b | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TTC39B mRNA | CTD | PMID:33387578 | Ttc39b | Rat | Heptachlor epoxide | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | Heptachlor Epoxide results in increased expression of TTC39B mRNA | CTD | PMID:25270620 | Ttc39b | Rat | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of TTC39B mRNA | CTD | PMID:21396975 | Ttc39b | Rat | inulin | multiple interactions | ISO | Ttc39b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TTC39B mRNA | CTD | PMID:36331819 | Ttc39b | Rat | Licochalcone B | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | licochalcone B results in decreased expression of TTC39B mRNA | CTD | PMID:33647349 | Ttc39b | Rat | manganese atom | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of TTC39B mRNA | CTD | PMID:39836092 | Ttc39b | Rat | manganese(0) | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of TTC39B mRNA | CTD | PMID:39836092 | Ttc39b | Rat | manganese(II) chloride | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [manganese chloride results in increased abundance of Manganese] which results in increased expression of TTC39B mRNA | CTD | PMID:39836092 | Ttc39b | Rat | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of TTC39B mRNA | CTD | PMID:19564919 | Ttc39b | Rat | methidathion | decreases expression | ISO | Ttc39b (Mus musculus) | 6480464 | methidathion results in decreased expression of TTC39B mRNA | CTD | PMID:34813904 | Ttc39b | Rat | naphthalene | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | naphthalene results in increased expression of TTC39B mRNA | CTD | PMID:18978301 | Ttc39b | Rat | paracetamol | affects expression | ISO | Ttc39b (Mus musculus) | 6480464 | Acetaminophen affects the expression of TTC39B mRNA | CTD | PMID:17562736 | Ttc39b | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TTC39B mRNA | CTD | PMID:33387578 | Ttc39b | Rat | paracetamol | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TTC39B mRNA | CTD | PMID:29067470 | Ttc39b | Rat | perfluorononanoic acid | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of TTC39B mRNA | CTD | PMID:32588087 | Ttc39b | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Ttc39b (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of TTC39B mRNA | CTD | PMID:36331819 | Ttc39b | Rat | phenobarbital | affects expression | ISO | Ttc39b (Mus musculus) | 6480464 | Phenobarbital affects the expression of TTC39B mRNA | CTD | PMID:23091169 | Ttc39b | Rat | pirinixic acid | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TTC39B mRNA | CTD | PMID:17426115 | Ttc39b | Rat | pirinixic acid | decreases expression | ISO | Ttc39b (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TTC39B mRNA | CTD | PMID:23811191 | Ttc39b | Rat | progesterone | affects expression | ISO | Ttc39b (Mus musculus) | 6480464 | Progesterone affects the expression of TTC39B mRNA | CTD | PMID:17251523 | Ttc39b | Rat | propiconazole | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | propiconazole results in increased expression of TTC39B mRNA | CTD | PMID:21278054 | Ttc39b | Rat | rac-lactic acid | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of TTC39B mRNA | CTD | PMID:30851411 | Ttc39b | Rat | SB 431542 | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TTC39B mRNA | CTD | PMID:27188386 | Ttc39b | Rat | silicon dioxide | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of TTC39B mRNA | CTD | PMID:25895662 | Ttc39b | Rat | sodium arsenate | multiple interactions | ISO | TTC39B (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of TTC39B mRNA | CTD | PMID:32525701 | Ttc39b | Rat | sodium arsenite | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TTC39B mRNA | CTD | PMID:34032870 and PMID:38568856 | Ttc39b | Rat | sodium arsenite | decreases expression | ISO | Ttc39b (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TTC39B mRNA | CTD | PMID:37682722 | Ttc39b | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of TTC39B mRNA | CTD | PMID:19281266 | Ttc39b | Rat | sunitinib | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TTC39B mRNA | CTD | PMID:31533062 | Ttc39b | Rat | temozolomide | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Temozolomide results in increased expression of TTC39B mRNA | CTD | PMID:31758290 | Ttc39b | Rat | thiram | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Thiram results in increased expression of TTC39B mRNA | CTD | PMID:38568856 | Ttc39b | Rat | titanium dioxide | decreases expression | ISO | Ttc39b (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of TTC39B mRNA | CTD | PMID:29264374 | Ttc39b | Rat | titanium dioxide | decreases methylation | ISO | Ttc39b (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TTC39B gene | CTD | PMID:35295148 | Ttc39b | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of TTC39B mRNA | CTD | PMID:33387578 | Ttc39b | Rat | trichostatin A | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TTC39B mRNA | CTD | PMID:24935251 | Ttc39b | Rat | trimellitic anhydride | increases expression | ISO | Ttc39b (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of TTC39B mRNA | CTD | PMID:19042947 | Ttc39b | Rat | triphenyl phosphate | affects expression | ISO | TTC39B (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TTC39B mRNA | CTD | PMID:37042841 | Ttc39b | Rat | trovafloxacin | decreases expression | ISO | Ttc39b (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of TTC39B mRNA | CTD | PMID:35537566 | Ttc39b | Rat | valproic acid | decreases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TTC39B mRNA | CTD | PMID:23179753 and PMID:28001369 | Ttc39b | Rat | valproic acid | increases expression | ISO | TTC39B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TTC39B mRNA | CTD | PMID:24935251 and PMID:27188386 | |