Snx10 (sorting nexin 10) - Rat Genome Database

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Gene: Snx10 (sorting nexin 10) Rattus norvegicus
Analyze
Symbol: Snx10
Name: sorting nexin 10
RGD ID: 1305782
Description: Predicted to enable 1-phosphatidylinositol binding activity; ATPase binding activity; and phosphatidylinositol phosphate binding activity. Predicted to be involved in several processes, including endosome organization; osteoclast differentiation; and protein localization to organelle. Predicted to act upstream of or within several processes, including bone mineralization involved in bone maturation; bone resorption; and cellular response to leukemia inhibitory factor. Predicted to be located in several cellular components, including apical cytoplasm; centrosome; and secretory granule. Predicted to be extrinsic component of endosome membrane. Predicted to be active in endosome. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 8. Orthologous to human SNX10 (sorting nexin 10); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC297096; MGC109202; sorting nexin-10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8481,943,262 - 82,007,667 (+)NCBIGRCr8
mRatBN7.2480,612,648 - 80,677,005 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl480,612,669 - 80,676,996 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx485,837,043 - 85,902,896 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0481,612,448 - 81,678,303 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,044,763 - 80,107,193 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0481,311,490 - 81,375,248 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl481,311,490 - 81,374,158 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04145,977,387 - 146,041,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4479,789,556 - 79,853,215 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1480,065,685 - 80,129,343 (+)NCBI
Celera475,513,406 - 75,574,707 (+)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2-palmitoylglycerol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
apilimod  (ISO)
aristolochic acid A  (ISO)
belinostat  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP,ISO)
coumestrol  (ISO)
Cuprizon  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fipronil  (EXP)
flutamide  (EXP)
fulvestrant  (ISO)
furan  (EXP)
glycine betaine  (EXP)
indole-3-methanol  (EXP)
inulin  (ISO)
kojic acid  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
Muraglitazar  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
orphenadrine  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
temozolomide  (ISO)
Tesaglitazar  (EXP)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP,ISO)
triptonide  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (ISO)
vinclozolin  (EXP)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:17012226   PMID:20439489   PMID:21844891   PMID:22174188   PMID:25811986   PMID:28381192  


Genomics

Comparative Map Data
Snx10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8481,943,262 - 82,007,667 (+)NCBIGRCr8
mRatBN7.2480,612,648 - 80,677,005 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl480,612,669 - 80,676,996 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx485,837,043 - 85,902,896 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0481,612,448 - 81,678,303 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0480,044,763 - 80,107,193 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0481,311,490 - 81,375,248 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl481,311,490 - 81,374,158 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04145,977,387 - 146,041,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4479,789,556 - 79,853,215 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1480,065,685 - 80,129,343 (+)NCBI
Celera475,513,406 - 75,574,707 (+)NCBICelera
Cytogenetic Map4q24NCBI
SNX10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38726,291,862 - 26,374,383 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl726,291,862 - 26,374,383 (+)EnsemblGRCh38hg38GRCh38
GRCh37726,331,482 - 26,414,003 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36726,298,040 - 26,380,474 (+)NCBINCBI36Build 36hg18NCBI36
Build 34726,104,754 - 26,187,187NCBI
Celera726,320,523 - 26,402,976 (+)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef726,213,196 - 26,295,663 (+)NCBIHuRef
CHM1_1726,331,091 - 26,413,549 (+)NCBICHM1_1
T2T-CHM13v2.0726,427,536 - 26,510,069 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2726,382,693 - 26,465,116 (+)NCBI
Snx10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39651,500,882 - 51,567,659 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl651,500,881 - 51,567,659 (+)EnsemblGRCm39 Ensembl
GRCm38651,523,900 - 51,590,679 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl651,523,901 - 51,590,679 (+)EnsemblGRCm38mm10GRCm38
MGSCv37651,473,902 - 51,540,669 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36651,474,106 - 51,520,253 (+)NCBIMGSCv36mm8
Celera652,041,831 - 52,108,565 (+)NCBICelera
Cytogenetic Map6B3NCBI
cM Map624.95NCBI
Snx10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541028,137,426 - 28,178,814 (+)NCBIChiLan1.0ChiLan1.0
SNX10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2631,119,435 - 31,201,532 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1779,444,161 - 79,526,258 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0726,935,357 - 27,017,461 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1726,537,519 - 26,618,862 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl726,537,189 - 26,620,720 (+)Ensemblpanpan1.1panPan2
SNX10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11439,567,701 - 39,642,475 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1439,567,471 - 39,640,872 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,058,554 - 39,132,699 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01439,506,523 - 39,581,109 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1439,506,054 - 39,581,109 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11439,621,497 - 39,695,665 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01439,308,572 - 39,382,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01439,659,123 - 39,733,270 (+)NCBIUU_Cfam_GSD_1.0
Snx10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511883,837,104 - 83,901,879 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,048,691 - 3,114,876 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364783,048,801 - 3,113,610 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SNX10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1846,064,580 - 46,142,945 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11846,064,575 - 46,142,983 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,838,880 - 50,917,745 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SNX10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,999,253 - 32,044,967 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,998,277 - 32,081,843 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604272,631,259 - 72,716,109 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Snx10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247394,209,036 - 4,233,519 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247394,210,840 - 4,274,768 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Snx10
457 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:82
Count of miRNA genes:61
Interacting mature miRNAs:73
Transcripts:ENSRNOT00000016265
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)47888281783007655Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45711443281266970Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)46293350882490359Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000016265   ⟹   ENSRNOP00000016265
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl480,612,669 - 80,676,995 (+)Ensembl
Rnor_6.0 Ensembl481,311,490 - 81,374,158 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000117927   ⟹   ENSRNOP00000095533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl480,658,967 - 80,676,996 (+)Ensembl
RefSeq Acc Id: NM_001013085   ⟹   NP_001013103
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8481,943,323 - 82,006,581 (+)NCBI
mRatBN7.2480,612,696 - 80,675,918 (+)NCBI
Rnor_6.0481,311,490 - 81,374,162 (+)NCBI
Rnor_5.04145,977,387 - 146,041,212 (+)NCBI
RGSC_v3.4479,789,556 - 79,853,215 (+)RGD
Celera475,513,406 - 75,574,707 (+)RGD
Sequence:
RefSeq Acc Id: XM_006236486   ⟹   XP_006236548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8481,962,393 - 82,007,667 (+)NCBI
mRatBN7.2480,631,782 - 80,676,999 (+)NCBI
Rnor_6.0481,330,596 - 81,375,248 (+)NCBI
Rnor_5.04145,977,387 - 146,041,212 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236488   ⟹   XP_006236550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8481,971,108 - 82,007,667 (+)NCBI
mRatBN7.2480,640,484 - 80,676,999 (+)NCBI
Rnor_6.0481,339,041 - 81,375,248 (+)NCBI
Rnor_5.04145,977,387 - 146,041,212 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236489   ⟹   XP_006236551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8481,963,151 - 82,007,667 (+)NCBI
mRatBN7.2480,632,527 - 80,676,999 (+)NCBI
Rnor_6.0481,331,314 - 81,375,248 (+)NCBI
Rnor_5.04145,977,387 - 146,041,212 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006236490   ⟹   XP_006236552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8481,962,405 - 82,007,667 (+)NCBI
mRatBN7.2480,631,888 - 80,676,999 (+)NCBI
Rnor_6.0481,330,670 - 81,375,248 (+)NCBI
Rnor_5.04145,977,387 - 146,041,212 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107307   ⟹   XP_038963235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8481,943,262 - 82,007,667 (+)NCBI
mRatBN7.2480,612,648 - 80,676,999 (+)NCBI
RefSeq Acc Id: NP_001013103   ⟸   NM_001013085
- UniProtKB: Q5BJX4 (UniProtKB/TrEMBL),   A0A8I6APC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236548   ⟸   XM_006236486
- Peptide Label: isoform X1
- UniProtKB: Q5BJX4 (UniProtKB/TrEMBL),   A0A8I6APC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236552   ⟸   XM_006236490
- Peptide Label: isoform X1
- UniProtKB: Q5BJX4 (UniProtKB/TrEMBL),   A0A8I6APC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236551   ⟸   XM_006236489
- Peptide Label: isoform X1
- UniProtKB: Q5BJX4 (UniProtKB/TrEMBL),   A0A8I6APC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236550   ⟸   XM_006236488
- Peptide Label: isoform X1
- UniProtKB: Q5BJX4 (UniProtKB/TrEMBL),   A0A8I6APC8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000016265   ⟸   ENSRNOT00000016265
RefSeq Acc Id: XP_038963235   ⟸   XM_039107307
- Peptide Label: isoform X1
- UniProtKB: Q5BJX4 (UniProtKB/TrEMBL),   A0A8I6APC8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095533   ⟸   ENSRNOT00000117927
Protein Domains
PX

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJX4-F1-model_v2 AlphaFold Q5BJX4 1-201 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693047
Promoter ID:EPDNEW_R3572
Type:initiation region
Name:Snx10_1
Description:sorting nexin 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0481,311,456 - 81,311,516EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305782 AgrOrtholog
BioCyc Gene G2FUF-44853 BioCyc
Ensembl Genes ENSRNOG00000011944 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016265.6 UniProtKB/TrEMBL
  ENSRNOT00000117927.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1520.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7306793 IMAGE-MGC_LOAD
InterPro IPR001683 UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  SNX10/11 UniProtKB/TrEMBL
KEGG Report rno:297096 UniProtKB/TrEMBL
MGC_CLONE MGC:109202 IMAGE-MGC_LOAD
NCBI Gene 297096 ENTREZGENE
PANTHER PTHR46209 UniProtKB/TrEMBL
  SORTING NEXIN-10 UniProtKB/TrEMBL
Pfam PF00787 UniProtKB/TrEMBL
PhenoGen Snx10 PhenoGen
PROSITE PS50195 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011944 RatGTEx
SMART SM00312 UniProtKB/TrEMBL
Superfamily-SCOP 64268 UniProtKB/TrEMBL
UniProt A0A8I6APC8 ENTREZGENE, UniProtKB/TrEMBL
  A6K0P3_RAT UniProtKB/TrEMBL
  F7FI04_RAT UniProtKB/TrEMBL
  Q5BJX4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Snx10  sorting nexin 10  Snx10_predicted  sorting nexin 10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Snx10_predicted  sorting nexin 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED