Mkx (mohawk homeobox) - Rat Genome Database

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Gene: Mkx (mohawk homeobox) Rattus norvegicus
Analyze
Symbol: Mkx
Name: mohawk homeobox
RGD ID: 1305652
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in several processes, including cellular response to mechanical stimulus; intratendonous ossification; and negative regulation of cell differentiation. Predicted to be active in nucleus. Orthologous to human MKX (mohawk homeobox); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein Mohawk; iroquois homeobox protein-like 1; Irxl1; LOC100912277; LOC103694111; LOC291228; RGD1305652; similar to hypothetical protein MGC39616; uncharacterized LOC100912277; uncharacterized LOC103694111
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Mkxem1Asah  
Genetic Models: WI-Mkxem1Asah
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21755,077,073 - 55,156,877 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,077,540 - 55,156,124 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01760,537,615 - 60,553,284 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,537,935 - 60,549,750 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01762,321,329 - 62,332,471 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,631,540 - 63,710,138 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11763,642,477 - 63,722,172 (-)NCBI
Celera1756,416,753 - 56,495,058 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis. Suzuki H, etal., Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7840-5. doi: 10.1073/pnas.1522054113. Epub 2016 Jul 1.
Additional References at PubMed
PMID:16408284   PMID:19235719   PMID:20498044   PMID:20696843   PMID:21254332   PMID:22923612   PMID:28750046  


Genomics

Comparative Map Data
Mkx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21755,077,073 - 55,156,877 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1755,077,540 - 55,156,124 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01760,537,615 - 60,553,284 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1760,537,935 - 60,549,750 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01762,321,329 - 62,332,471 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41763,631,540 - 63,710,138 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11763,642,477 - 63,722,172 (-)NCBI
Celera1756,416,753 - 56,495,058 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
MKX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381027,672,874 - 27,745,819 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1027,672,874 - 27,746,060 (-)EnsemblGRCh38hg38GRCh38
GRCh371027,961,803 - 28,034,748 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361028,001,809 - 28,074,753 (-)NCBINCBI36Build 36hg18NCBI36
Build 341028,001,811 - 28,074,753NCBI
Celera1027,725,254 - 27,798,252 (-)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1027,678,080 - 27,751,075 (-)NCBIHuRef
CHM1_11027,961,725 - 28,034,733 (-)NCBICHM1_1
T2T-CHM13v2.01027,703,607 - 27,776,565 (-)NCBIT2T-CHM13v2.0
Mkx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39186,934,966 - 7,004,779 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl186,934,518 - 7,004,780 (-)EnsemblGRCm39 Ensembl
GRCm38186,934,966 - 7,004,779 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl186,934,518 - 7,004,780 (-)EnsemblGRCm38mm10GRCm38
MGSCv37186,934,964 - 7,004,777 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36186,934,998 - 7,004,754 (-)NCBIMGSCv36mm8
Celera186,980,394 - 7,049,750 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.53NCBI
Mkx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554621,564,191 - 1,631,951 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554621,564,739 - 1,631,613 (-)NCBIChiLan1.0ChiLan1.0
MKX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11040,346,145 - 40,420,917 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01027,820,454 - 27,893,373 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11028,181,483 - 28,254,311 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1028,181,483 - 28,254,311 (-)Ensemblpanpan1.1panPan2
LOC487079
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.125,898,155 - 5,964,577 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha24,371,377 - 4,437,081 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.024,651,755 - 4,720,172 (+)NCBIROS_Cfam_1.0
UNSW_CanFamBas_1.0216,010,859 - 16,077,012 (+)NCBIUNSW_CanFamBas_1.0
Mkx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093447,469,239 - 7,533,485 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366132,019,783 - 2,084,267 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366132,019,815 - 2,083,724 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MKX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1039,096,782 - 39,172,198 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11039,096,778 - 39,173,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21053,679,406 - 53,744,157 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MKX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1927,228,061 - 27,305,852 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605133,247,101 - 33,322,551 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mkx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248056,061,635 - 6,121,926 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248056,060,131 - 6,122,305 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mkx
420 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:18
Count of miRNA genes:16
Interacting mature miRNAs:18
Transcripts:ENSRNOT00000025623
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat
1354628Stl13Serum triglyceride level QTL 133.8blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)172129303960781592Rat
61394Bp8Blood pressure QTL 82.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172308056759555013Rat
7488966Bp370Blood pressure QTL 3700.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318457246843Rat
12903978Cm118Cardiac mass QTL 1180.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)172365318468653184Rat
12903979Cm119Cardiac mass QTL 1190.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172365318468653184Rat
12903980Cm120Cardiac mass QTL 1200.002heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)172365318468653184Rat
12903981Am17Aortic mass QTL 170.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)172365318468653184Rat
1559055Bp278Blood pressure QTL 2780.04arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)172365318468653184Rat
12903982Kidm70Kidney mass QTL 700.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)172365318470974005Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)172459934069599340Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172702794956836890Rat
4889955Bss93Bone structure and strength QTL 934.4tibia size trait (VT:0100001)tibia cortical bone volume to tibia total bone volume ratio (CMO:0001727)172702794960463643Rat
8552928Pigfal9Plasma insulin-like growth factor 1 level QTL 99blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)172840914773409147Rat
9590107Sffal7Serum free fatty acids level QTL 74.810.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)172840914773409147Rat
10450503Bp386Blood pressure QTL 3860.28arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173136839162109574Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)173136839173951021Rat
724549Niddm56Non-insulin dependent diabetes mellitus QTL 560.03blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)173199078476990784Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173199078481292925Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)173455084373951021Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173583708569599340Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)173747984782479847Rat
2317054Aia12Adjuvant induced arthritis QTL 124.24joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)173828150983281509Rat
2317060Aia26Adjuvant induced arthritis QTL 263.22joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)173828150983281509Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174054004180387013Rat
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
631497Bp98Blood pressure QTL 983.66arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)174135465160463643Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)174207316069599340Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)174207316069599340Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)175089090860781592Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)175089090860781592Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2317053Aia25Adjuvant induced arthritis QTL 252.69joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)175090919660781426Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175349882882479847Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)175402992960463637Rat

Markers in Region
RH137808  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21755,126,021 - 55,126,197 (-)MAPPERmRatBN7.2
Rnor_6.01760,573,754 - 60,573,929NCBIRnor6.0
Rnor_5.01762,354,027 - 62,354,202UniSTSRnor5.0
RGSC_v3.41763,678,182 - 63,678,357UniSTSRGSC3.4
RH 3.4 Map17557.0UniSTS
Cytogenetic Map17q12.1UniSTS


Genetic Models
This gene Mkx is modified in the following models/strains

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 18 22 6 8 6 8 10 74 23 40 7 8
Below cutoff 1 21 16 16 9 16 1 12 1 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000025623   ⟹   ENSRNOP00000025623
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1755,077,540 - 55,156,124 (-)Ensembl
Rnor_6.0 Ensembl1760,537,935 - 60,549,750 (+)Ensembl
RefSeq Acc Id: XM_008771811   ⟹   XP_008770033
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21755,077,073 - 55,155,933 (-)NCBI
Rnor_6.01760,537,970 - 60,553,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017600733   ⟹   XP_017456222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21755,077,073 - 55,156,877 (-)NCBI
Rnor_6.01760,537,615 - 60,553,284 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039096145   ⟹   XP_038952073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21755,077,073 - 55,154,919 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008770033 (Get FASTA)   NCBI Sequence Viewer  
  XP_017456222 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952073 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL83768 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_008770033   ⟸   XM_008771811
- UniProtKB: D3ZUL2 (UniProtKB/TrEMBL),   A6KPM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017456222   ⟸   XM_017600733
- UniProtKB: D3ZUL2 (UniProtKB/TrEMBL),   A6KPM3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000025623   ⟸   ENSRNOT00000025623
RefSeq Acc Id: XP_038952073   ⟸   XM_039096145
- UniProtKB: D3ZUL2 (UniProtKB/TrEMBL),   A6KPM3 (UniProtKB/TrEMBL)
Protein Domains
Homeobox

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUL2-F1-model_v2 AlphaFold D3ZUL2 1-315 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305652 AgrOrtholog
BioCyc Gene G2FUF-8970 BioCyc
Ensembl Genes ENSRNOG00000018938 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000025623 ENTREZGENE
  ENSRNOP00000025623.8 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025623 ENTREZGENE
  ENSRNOT00000025623.8 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
KEGG Report rno:291228 UniProtKB/TrEMBL
NCBI Gene 291228 ENTREZGENE
PANTHER HOMEOBOX PROTEIN MOHAWK UniProtKB/TrEMBL
  IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
PhenoGen Mkx PhenoGen
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A6KPM3 ENTREZGENE, UniProtKB/TrEMBL
  D3ZUL2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Mkx  mohawk homeobox  LOC103694111  uncharacterized LOC103694111  Data Merged 737654 PROVISIONAL
2015-07-29 LOC103694111  uncharacterized LOC103694111  LOC100912277  uncharacterized LOC100912277  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103694111  uncharacterized LOC103694111      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100912277  uncharacterized LOC100912277      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-04 Mkx  mohawk homeobox  Irxl1_predicted  iroquois homeobox protein-like 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Irxl1_predicted  iroquois homeobox protein-like 1 (predicted)  RGD1305652_predicted  similar to hypothetical protein MGC39616 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1305652_predicted  similar to hypothetical protein MGC39616 (predicted)  LOC291228_predicted  similar to hypothetical protein MGC39616 (predicted)  Symbol and Name status set to approved 1331353 APPROVED
2005-01-20 RGD1305652_predicted  similar to hypothetical protein MGC39616 (predicted)  LOC291228_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC291228_predicted  similar to hypothetical protein MGC39616 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL