Advanced Search (OLGA)

Gene: Cox19 (cytochrome c oxidase assembly factor COX19) Rattus norvegicus

Analyze

Symbol:

Cox19

Name:

cytochrome c oxidase assembly factor COX19

RGD ID:

1305631

Description:

Predicted to be involved in intracellular copper ion homeostasis. Predicted to be located in cytosol and mitochondrial intermembrane space. Orthologous to human COX19 (cytochrome c oxidase assembly factor COX19); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

COX19 cytochrome c oxidase assembly factor; COX19 cytochrome c oxidase assembly homolog; COX19 cytochrome c oxidase assembly homolog (S. cerevisiae); cytochrome c oxidase assembly factor; cytochrome c oxidase assembly homolog 19; cytochrome c oxidase assembly homolog 19 (S. cerevisiae); cytochrome c oxidase assembly protein 19; LOC304330; RGD1305631; similar to 2810437L13Rik protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	COX19 (cytochrome c oxidase assembly factor COX19)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Cox19 (cytochrome c oxidase assembly protein 19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	LOC102014331 (cytochrome c oxidase assembly protein COX19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LOC100995989 (cytochrome c oxidase assembly protein COX19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	COX19 (cytochrome c oxidase assembly factor COX19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101965505 (cytochrome c oxidase assembly protein COX19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	COX19 (cytochrome c oxidase assembly factor COX19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	COX19 (COX19, cytochrome c oxidase assembly factor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	LOC101702478 (cytochrome c oxidase assembly protein COX19)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Cox19 (cytochrome c oxidase assembly protein 19)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	COX19 (cytochrome c oxidase assembly factor COX19)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cox19 (cytochrome c oxidase assembly factor COX19)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG42496	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	COX19	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	cox-19	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cox19	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	20,417,389 - 20,426,868 (+)	NCBI		GRCr8
mRatBN7.2	12	15,303,535 - 15,313,014 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	15,303,551 - 15,313,014 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	16,113,642 - 16,123,131 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	16,737,382 - 16,746,871 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	15,763,523 - 15,773,011 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	17,395,624 - 17,405,103 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	17,395,624 - 17,405,103 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	19,381,857 - 19,391,336 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	15,804,279 - 15,812,139 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	15,834,214 - 15,841,823 (+)	NCBI
Celera	12	17,057,525 - 17,067,004 (+)	NCBI		Celera
Cytogenetic Map	12	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3,4-methylenedioxymethamphetamine (EXP)

4,4'-sulfonyldiphenol (ISO)

avobenzone (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

butan-1-ol (ISO)

butanal (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

clobetasol (ISO)

copper atom (ISO)

copper(0) (ISO)

dorsomorphin (ISO)

ethyl methanesulfonate (ISO)

finasteride (EXP)

flutamide (EXP)

folic acid (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

nefazodone (EXP)

nimesulide (EXP)

paracetamol (EXP)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

quercetin (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium dodecyl sulfate (ISO)

T-2 toxin (ISO)

tetracycline (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

tunicamycin (ISO)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular copper ion homeostasis (ISO)

Cellular Component

cytoplasm (IEA)

cytosol (ISO)

mitochondrial intermembrane space (ISO)

mitochondrion (IEA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23345593	PMID:23676665

Genomics

Comparative Map Data

Cox19
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	20,417,389 - 20,426,868 (+)	NCBI		GRCr8
mRatBN7.2	12	15,303,535 - 15,313,014 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	15,303,551 - 15,313,014 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	16,113,642 - 16,123,131 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	16,737,382 - 16,746,871 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	15,763,523 - 15,773,011 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	17,395,624 - 17,405,103 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	17,395,624 - 17,405,103 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	19,381,857 - 19,391,336 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	15,804,279 - 15,812,139 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	15,834,214 - 15,841,823 (+)	NCBI
Celera	12	17,057,525 - 17,067,004 (+)	NCBI		Celera
Cytogenetic Map	12	q11	NCBI

COX19
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	964,852 - 975,549 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	898,778 - 975,549 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	1,004,488 - 1,015,185 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	971,012 - 981,761 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	972,231 - 982,979 (-)	NCBI		Celera
Cytogenetic Map	7	p22.3	NCBI
HuRef	7	921,398 - 931,903 (-)	NCBI		HuRef
CHM1_1	7	1,003,581 - 1,014,326 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	1,069,849 - 1,080,546 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	1,059,119 - 1,069,865 (-)	NCBI

Cox19
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	139,323,577 - 139,330,921 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	139,321,944 - 139,337,173 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	139,337,822 - 139,345,166 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	139,336,189 - 139,351,418 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	139,813,776 - 139,821,120 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	139,591,464 - 139,598,808 (-)	NCBI		MGSCv36	mm8
Celera	5	136,391,978 - 136,399,321 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	78.4	NCBI

LOC102014331
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955460	8,689,706 - 8,697,494 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955460	8,689,706 - 8,697,494 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100995989
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	5,914,148 - 5,920,373 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	54,242,645 - 54,244,893 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	1,126,328 - 1,132,999 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	1,337,290 - 1,345,755 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	1,337,290 - 1,345,755 (-)	Ensembl	panpan1.1		panPan2

COX19
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	15,897,702 - 15,908,020 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	15,897,774 - 15,904,998 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	17,370,817 - 17,381,137 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	16,028,433 - 16,038,766 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	6	15,831,287 - 15,841,600 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	15,757,828 - 15,768,142 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	16,046,026 - 16,056,359 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101965505
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	143,813,177 - 143,820,622 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936754	1,190,450 - 1,197,107 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936754	1,189,743 - 1,197,152 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COX19
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	630,481 - 635,280 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	627,889 - 635,340 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	758,363 - 763,230 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COX19
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	28	20,596,595 - 20,613,034 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	28	20,596,652 - 20,612,874 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666090	1,089,114 - 1,096,364 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

LOC101702478
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624740	26,528,803 - 26,539,135 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624740	26,528,930 - 26,539,080 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cox19
42 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	671
Count of miRNA genes:	288
Interacting mature miRNAs:	379
Transcripts:	ENSRNOT00000072509
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	1	19611090	Rat
61443	Btemp2	Thermal response to stress QTL 2	3.3	0.000094	body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	12	15025183	20794014	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	8525423	28064601	Rat
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	29333307	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	23297788	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	11073825	24234895	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	34851688	Rat
1600391	Edcs2	Endometrial carcinoma susceptibility QTL2	3.5	0.01	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	12	6833190	17870186	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
10755457	Coatc14	Coat color QTL 14		0.01759	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	12	1	22591684	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	13635523	30827399	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13008296	19212979	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
7387292	Kidm42	Kidney mass QTL 42	3.03	0.0004	kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	12	1	36247923	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	13635523	35682913	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	9318216	32103380	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	8449490	28302290	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	28064557	Rat

Markers in Region

RH133407

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	15,312,623 - 15,312,809 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	17,404,713 - 17,404,898	NCBI	Rnor6.0
Rnor_5.0	12	19,390,946 - 19,391,131	UniSTS	Rnor5.0
RGSC_v3.4	12	15,813,404 - 15,813,589	UniSTS	RGSC3.4
Celera	12	17,066,614 - 17,066,799	UniSTS
RH 3.4 Map	12	245.6	UniSTS
Cytogenetic Map	12	q11	UniSTS

AI454263

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	15,310,864 - 15,311,058 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	17,402,954 - 17,403,147	NCBI	Rnor6.0
Rnor_5.0	12	19,389,187 - 19,389,380	UniSTS	Rnor5.0
RGSC_v3.4	12	15,811,645 - 15,811,838	UniSTS	RGSC3.4
Celera	12	17,064,855 - 17,065,048	UniSTS
RH 3.4 Map	12	245.7	UniSTS
Cytogenetic Map	12	q11	UniSTS

AU049646

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	15,311,287 - 15,311,413 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	17,403,377 - 17,403,502	NCBI	Rnor6.0
Rnor_5.0	12	19,389,610 - 19,389,735	UniSTS	Rnor5.0
RGSC_v3.4	12	15,812,068 - 15,812,193	UniSTS	RGSC3.4
Celera	12	17,065,278 - 17,065,403	UniSTS
Cytogenetic Map	12	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107126	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC127903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000072509 ⟹ ENSRNOP00000064079

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	15,303,551 - 15,313,012 (+)	Ensembl
Rnor_6.0 Ensembl	12	17,395,624 - 17,405,103 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118930 ⟹ ENSRNOP00000089709

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	15,305,365 - 15,313,014 (+)	Ensembl

RefSeq Acc Id:

NM_001107126 ⟹ NP_001100596

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	20,417,389 - 20,426,868 (+)	NCBI
mRatBN7.2	12	15,303,535 - 15,313,014 (+)	NCBI
Rnor_6.0	12	17,395,624 - 17,405,103 (+)	NCBI
Rnor_5.0	12	19,381,857 - 19,391,336 (+)	NCBI
RGSC_v3.4	12	15,804,279 - 15,812,139 (+)	RGD
Celera	12	17,057,525 - 17,067,004 (+)	NCBI

Sequence:

show sequence

GCCGCTCTCCGCTCTTGATTTCGCCGTGATGTCGACCGCAATGAACTTCGGGACCAAAAGCTTC
CAGCCGCGGCCCCCAGACAAAGGCAGCTTCCCGCTAGACCACTTCGGTGAGTGTAAAAGCTTTA
AGGAAAAATTCATGAAGTGTCTCCGCGACAAGAACTATGAAAATGCTCTGTGCAGAAATGAATC
TAAAGAGTATTTAATGTGCAGGATGCAAAGGCAGCTGATGGCACCAGAACCACTAGAGAAACTC
GGCTTTAGAGACATAATGGAGGAGAAACCGGAGGCAAAGGACAAATGTTGAGAATCACTGGGCT
GTGTCCCCCTACCTGGAGCAGAGCTGAGCCCTTCTGCCCACCGTGGAGAGAGCTGAGCCATCCT
GTGCTGCCCAGAGGAGGGGCTCTCCGTGTTGACTTTGGCTCATCCCTGCAGCATAGACCAGACT
GCTTCCTCTACTGACCACACTTCTGCTTCAGAGAGTGGTTTTCTCCTGTCTGTGTGTGTCACAG
GATCTGCTCAGGGCTGAACACTGATGTGATATGATATCCCACCTAGTGTGGCCGTCACACCAGA
GGCCCTGGACAGCATTCCACAGTGACTCAACCTGAGTCCTCACACCGGAACCTGTCAGCGAAAC
CAAGCGACAGCAAAATGTCTGCCTTTTGTGCTCACAGACGCACATCATCTTGCTTCCCCTTCTC
TTGTGTTCTTTGCTTTGAACAAAACTGGAATACAAAGTAGGAAGTGAGAAATAGTTTGGCTTTT
GACATAGTTGACCTCCTGTTTTAAGTGTTTTGAGACAGGGTCTCAGACCGCCCGTGTACCCAAG
GATGACCTCGAACTCTTGATCCTTCTGCCTCCATGTCTAGGGTATTGGGGCATGGAACCCAGGG
CTCCCTGCACGATAGGCAAGCACTCTCTCAGCTGAACCGTGTCTCCAGCTAGGGAAGCACTGTA
TCTCAGTGTGTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTCAGAG
GACAACTTAGAGGAGTCCGATCTCTCCTTGCCCAAGTGAGTGTCTCAGGGATTGAACTCGGGTC
ACCAGGCTTGGTAGATGTCTCAGCTCAACTTCCATTCCCCCAGTCTAGGAGCAGATGGCTTCAT
GACGCGGGTTGGGTTATTTTCTGGTCGTCTCAAGCTGTCTGTAAACCTGGCTTTTCCTTTCAGT
GGCCCACCGCATGCCTCCACAGGGCGGGTCAGCCACGCACAGAGGCTGGGCTAGGATCTATCCC
TTTTCCACTGTTGCACCGTGTTGCAGTAACATTGCACTTACGTGTCTGTGGGTGCTGACGCTAA
CCCTGTACTGTCAGCACTGAGCAGCGCTGAGCTGTGGCTTAGCCCAGGCTATCCTCAGAGTTCC
CTGTGGGTTGTTTAAACACCCAGGCGCCTTCATCCTGAGGCAGGTGATGGGAAGGGGGGAGCAG
CTGGGTTCGGGGCTTCTGCTGTGTGCAGGGATCCAAAGACACCAGCAGAACGCCAGTGCCAGGT
GTTGTCAGGCTCCAGTGCCTCAGATGTGTCCTCCTAGAGCTGTTGGAGAAGGGCTGTCCCCCTG
CTTGTCCTGGCTCCTGTCTGACTGGTGAAGGACACCATGGGTGGGATGGGGCAGGTATTGTGGC
GCACAACTTTAGCACCCAAGAGGCAGAGGCAGGCAGATCCTTGAGTTTGAGGCCAGTTTTGTCT
ACAGAGTGAGTTGTAGGAGAGCCAGGACGACATAGAGAGAGAGAGACCCTCTGGGGTTGGGGCA
GAGGGTGGGAGAGAGAAACGGGGATGGGAAGAGGACTTCGTATATTCATATCCCTGTTGGTCTT
AGGCTCTGGCACTGCGAGGCCTGCAGGGTCTGCTGATCTCCTGGGGGCAGCTTCCCCTTCCCCA
GGAGATGTGAGCGCCTGTGAGCCTGGTTTGCTGTTACACAGAAAGACCTCTTCCTGGTTGGACC
CATAGTCCTGCACACCGGGGTCTGCTTGTTCACACACTCGCTCAGCCCGGCCACACAGAGCGGG
GCAGCACCAGGTCCACATGTCACGTTTGAGCCTTGGTTTTTATCACCAACATTAGTGTCACCGC
AGTACTGTGGTGTTGGAGCAGCCAAGCTCACTTGTTAGGACTCGAGGTGTGTGGCGAGCACTCC
AGTGACTGGGCCATCTCCTCGGCCATTTTGTTGTGTCTGTTTATCAAGAGAGGGCCCACTCTGT
AGCCAAGGCTGGCCTTGAACTCTGTTTCCACCTCCCAAGTCCTGCCATCTTCCAAGCCTTTGAT
GTCTGTTATCAGCAAGTGACAAAATGAACATATGTCACAGTCAAGTACGGCTGAGTTTTCCAAC
ACATCACGGCGGCTCCATCCACGAGTGCCCCACTTGTCCACCCATCTCCAGCGAGATGCAGGAA
CACAGCATAGCAACACTGATGGCTTTGGGGCTGGAGTTGGAGGATGCTCGGTTCCCTCCTGGGA
TGTTCACGGTTATATCTTATAACAAGTGTGCATCATTTTTATAGAAACTATAAAATCCTTACTT
GAAGGGAACTCACCGTGTTGAGTAGTGTTTCCATATCCTCTGTAAATTACAGGCCAGTTGTAAT
TTCTAATCCCCTGTGGATACCAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001100596	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL89771	(Get FASTA)	NCBI Sequence Viewer
	EDL89772	(Get FASTA)	NCBI Sequence Viewer
	EDL89773	(Get FASTA)	NCBI Sequence Viewer
	EDL89774	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000064079.2
	ENSRNOP00000089709
	ENSRNOP00000089709.1

RefSeq Acc Id:	NP_001100596 ⟸ NM_001107126
- UniProtKB:	A6K1W3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSTAMNFGTKSFQPRPPDKGSFPLDHFGECKSFKEKFMKCLRDKNYENALCRNESKEYLMCRMQ RQLMAPEPLEKLGFRDIMEEKPEAKDKC hide sequence

Ensembl Acc Id:

ENSRNOP00000064079 ⟸ ENSRNOT00000072509

Ensembl Acc Id:

ENSRNOP00000089709 ⟸ ENSRNOT00000118930

Protein Domains

CHCH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZIS5-F1-model_v2	AlphaFold	D3ZIS5	1-92	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698468

Promoter ID:

EPDNEW_R8992

Type:

initiation region

Name:

Cox19_1

Description:

COX19 cytochrome c oxidase assembly factor

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	17,395,627 - 17,395,687	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305631	AgrOrtholog
BioCyc Gene	G2FUF-19888	BioCyc
Ensembl Genes	ENSRNOG00000050052	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000072509.2	UniProtKB/TrEMBL
	ENSRNOT00000118930	ENTREZGENE
	ENSRNOT00000118930.1	UniProtKB/TrEMBL
InterPro	CHCH	UniProtKB/TrEMBL
	COX19	UniProtKB/TrEMBL
	Cys_alpha_HP_mot_SF	UniProtKB/TrEMBL
KEGG Report	rno:304330	UniProtKB/TrEMBL
NCBI Gene	304330	ENTREZGENE
PANTHER	CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19	UniProtKB/TrEMBL
	CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX19	UniProtKB/TrEMBL
Pfam	CHCH	UniProtKB/TrEMBL
PhenoGen	Cox19	PhenoGen
PROSITE	CHCH	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000050052	RatGTEx
Superfamily-SCOP	SSF47072	UniProtKB/TrEMBL
UniProt	A0A8I6GHK2_RAT	UniProtKB/TrEMBL
	A6K1W3	ENTREZGENE, UniProtKB/TrEMBL
	D3ZIS5_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-07-20	Cox19	cytochrome c oxidase assembly factor COX19	Cox19	COX19 cytochrome c oxidase assembly factor	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-12-04	Cox19	COX19 cytochrome c oxidase assembly factor	Cox19	cytochrome c oxidase assembly factor	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-12-02	Cox19	cytochrome c oxidase assembly factor	Cox19	cytochrome c oxidase assembly protein 19	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-12-01	Cox19	cytochrome c oxidase assembly protein 19	Cox19	cytochrome c oxidase assembly homolog 19 (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-24	Cox19	cytochrome c oxidase assembly homolog 19 (S. cerevisiae)	Cox19	COX19 cytochrome c oxidase assembly homolog (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Cox19	COX19 cytochrome c oxidase assembly homolog (S. cerevisiae)	RGD1305631_predicted	similar to 2810437L13Rik protein (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	RGD1305631_predicted	similar to 2810437L13Rik protein (predicted)	LOC304330_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC304330_predicted	similar to 2810437L13Rik protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message