Sar1b (secretion associated, Ras related GTPase 1B) - Rat Genome Database

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Pathways
Gene: Sar1b (secretion associated, Ras related GTPase 1B) Rattus norvegicus
Analyze
Symbol: Sar1b
Name: secretion associated, Ras related GTPase 1B
RGD ID: 1305590
Description: Predicted to enable GTPase activity. Predicted to be involved in several processes, including positive regulation of protein exit from endoplasmic reticulum; protein transport; and regulation of COPII vesicle coating. Predicted to be located in Golgi cisterna membrane and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Human ortholog(s) of this gene implicated in chylomicron retention disease. Orthologous to human SAR1B (secretion associated Ras related GTPase 1B); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: GTP-binding protein SAR1b; LOC287276; SAR1 gene homolog B; SAR1 gene homolog B (S. cerevisiae); SAR1 homolog B; SAR1 homolog B (S. cerevisiae); SAR1a gene homolog 2; SAR1a gene homolog 2 (S. cerevisiae); SARA1B; Sara2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
NCBI Annotation Information: Annotation category: suggests misassembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21036,024,415 - 36,054,069 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1036,024,382 - 36,054,066 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1040,718,637 - 40,749,185 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01040,208,617 - 40,239,165 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01035,712,346 - 35,742,894 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01037,215,989 - 37,245,603 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,215,937 - 37,245,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01036,988,915 - 37,018,529 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,283,985 - 37,313,599 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11037,290,414 - 37,320,029 (+)NCBI
Celera1035,379,114 - 35,408,847 (+)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
dexamethasone  (ISO)
disulfiram  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
geldanamycin  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
indometacin  (ISO)
inulin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
leflunomide  (EXP)
mercury dibromide  (ISO)
methidathion  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
nicotine  (ISO)
nimesulide  (EXP)
ozone  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
thapsigargin  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:21480366   PMID:22303004   PMID:22484643  


Genomics

Comparative Map Data
Sar1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21036,024,415 - 36,054,069 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1036,024,382 - 36,054,066 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1040,718,637 - 40,749,185 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01040,208,617 - 40,239,165 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01035,712,346 - 35,742,894 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01037,215,989 - 37,245,603 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,215,937 - 37,245,658 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01036,988,915 - 37,018,529 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,283,985 - 37,313,599 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11037,290,414 - 37,320,029 (+)NCBI
Celera1035,379,114 - 35,408,847 (+)NCBICelera
Cytogenetic Map10q22NCBI
SAR1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385134,601,149 - 134,632,828 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5134,601,149 - 134,649,271 (-)EnsemblGRCh38hg38GRCh38
GRCh375133,936,839 - 133,968,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365133,970,018 - 133,996,426 (-)NCBINCBI36Build 36hg18NCBI36
Build 345133,970,018 - 133,996,426NCBI
Celera5130,062,739 - 130,094,663 (-)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5129,123,090 - 129,154,586 (-)NCBIHuRef
CHM1_15133,369,453 - 133,401,131 (-)NCBICHM1_1
T2T-CHM13v2.05135,126,762 - 135,158,446 (-)NCBIT2T-CHM13v2.0
Sar1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,654,490 - 51,682,780 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,654,514 - 51,682,752 (+)EnsemblGRCm39 Ensembl
GRCm381151,763,663 - 51,791,953 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,763,687 - 51,791,925 (+)EnsemblGRCm38mm10GRCm38
MGSCv371151,577,165 - 51,605,455 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361151,607,125 - 51,635,346 (+)NCBIMGSCv36mm8
Celera1156,330,790 - 56,359,078 (+)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.41NCBI
Sar1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554085,737,197 - 5,761,228 (-)NCBIChiLan1.0ChiLan1.0
SAR1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan15128,044,218 - 128,070,580 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05130,008,941 - 130,035,785 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15136,151,592 - 136,181,967 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5136,157,408 - 136,181,967 (-)Ensemblpanpan1.1panPan2
SAR1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,713,459 - 22,743,190 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,717,942 - 22,743,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1121,458,574 - 21,488,325 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01123,515,054 - 23,544,792 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1123,515,063 - 23,544,692 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,214,621 - 22,244,324 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01122,080,820 - 22,110,561 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,723,081 - 22,752,825 (-)NCBIUU_Cfam_GSD_1.0
Sar1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213113,695,139 - 113,722,293 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936647697,930 - 723,577 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SAR1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2136,843,955 - 136,874,213 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12136,848,843 - 136,874,248 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22142,463,692 - 142,489,104 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SAR1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12337,409,666 - 37,433,462 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2337,406,770 - 37,444,447 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603440,492,068 - 40,527,647 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sar1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473337,704,590 - 37,733,933 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473337,704,577 - 37,733,773 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sar1b
225 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:82
Count of miRNA genes:61
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000006567
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
631531Iresp2Immunoglobin response QTL26.3blood immunoglobulin E amount (VT:0002492)serum total immunoglobulin E level (CMO:0001542)102291826836400810Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103449055945579777Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103539226751793994Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat

Markers in Region
BI302268  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21036,052,518 - 36,052,639 (+)MAPPERmRatBN7.2
Rnor_6.01037,244,058 - 37,244,178NCBIRnor6.0
Rnor_5.01037,016,984 - 37,017,104UniSTSRnor5.0
RGSC_v3.41037,312,054 - 37,312,174UniSTSRGSC3.4
Celera1035,407,302 - 35,407,422UniSTS
RH 3.4 Map10388.0UniSTS
Cytogenetic Map10q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 40 11 8
Low 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001009622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC088842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV713786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000006567   ⟹   ENSRNOP00000006567
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1036,024,382 - 36,053,594 (+)Ensembl
Rnor_6.0 Ensembl1037,215,937 - 37,245,658 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102256   ⟹   ENSRNOP00000077131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1036,024,415 - 36,054,066 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106684   ⟹   ENSRNOP00000097629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1036,041,045 - 36,054,066 (+)Ensembl
RefSeq Acc Id: NM_001009622   ⟹   NP_001009622
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21036,024,415 - 36,054,069 (+)NCBI
Rnor_6.01037,215,989 - 37,245,603 (+)NCBI
Rnor_5.01036,988,915 - 37,018,529 (+)NCBI
RGSC_v3.41037,283,985 - 37,313,599 (+)RGD
Celera1035,379,114 - 35,408,847 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009622 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88842 (Get FASTA)   NCBI Sequence Viewer  
  EDM04331 (Get FASTA)   NCBI Sequence Viewer  
  EDM04332 (Get FASTA)   NCBI Sequence Viewer  
  Q5HZY2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001009622   ⟸   NM_001009622
- UniProtKB: Q5HZY2 (UniProtKB/Swiss-Prot),   A6HE76 (UniProtKB/TrEMBL),   A0A8I5Y776 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006567   ⟸   ENSRNOT00000006567
RefSeq Acc Id: ENSRNOP00000097629   ⟸   ENSRNOT00000106684
RefSeq Acc Id: ENSRNOP00000077131   ⟸   ENSRNOT00000102256

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5HZY2-F1-model_v2 AlphaFold Q5HZY2 1-198 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305590 AgrOrtholog
BioCyc Gene G2FUF-25186 BioCyc
Ensembl Genes ENSRNOG00000004820 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000006567 UniProtKB/Swiss-Prot
  ENSRNOP00000077131 ENTREZGENE
  ENSRNOP00000077131.1 UniProtKB/TrEMBL
  ENSRNOP00000097629.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006567 UniProtKB/Swiss-Prot
  ENSRNOT00000102256 ENTREZGENE
  ENSRNOT00000102256.1 UniProtKB/TrEMBL
  ENSRNOT00000106684.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7303357 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_ARF/SAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Small_GTPase_SAR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:287276 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105988 IMAGE-MGC_LOAD
NCBI Gene 287276 ENTREZGENE
PANTHER GTP-BINDING PROTEIN SAR1B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45684 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Arf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sar1b PhenoGen
PRINTS SAR1GTPBP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARF UniProtKB/TrEMBL
  SAR1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ARF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SAR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y776 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AWL3_RAT UniProtKB/TrEMBL
  A6HE76 ENTREZGENE, UniProtKB/TrEMBL
  A6HE77_RAT UniProtKB/TrEMBL
  Q5HZY2 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-03-13 Sar1b  secretion associated, Ras related GTPase 1B  Sar1b  SAR1 homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-30 Sar1b  SAR1 homolog B (S. cerevisiae)  Sar1b  SAR1 gene homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Sar1b  SAR1 gene homolog B (S. cerevisiae)  Sara2  SAR1a gene homolog 2 (S. cerevisiae)  Symbol and Name updated 1299863 APPROVED
2005-12-06 Sara2  SAR1a gene homolog 2 (S. cerevisiae)  Sara2_predicted  SAR1a gene homolog 2 (S. cerevisiae) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sara2_predicted  SAR1a gene homolog 2 (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED