Gtf2h3 (general transcription factor IIH subunit 3) - Rat Genome Database

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Gene: Gtf2h3 (general transcription factor IIH subunit 3) Rattus norvegicus
Analyze
Symbol: Gtf2h3
Name: general transcription factor IIH subunit 3
RGD ID: 1305494
Description: Predicted to enable RNA polymerase II general transcription initiation factor activity. Predicted to be involved in nucleotide-excision repair and transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of core TFIIH complex portion of holo TFIIH complex; transcription factor TFIID complex; and transcription preinitiation complex. Orthologous to human GTF2H3 (general transcription factor IIH subunit 3); PARTICIPATES IN RNA polymerase II transcription initiation pathway; nucleotide excision repair pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: general transcription factor IIH, polypeptide 3; LOC288651
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81237,669,995 - 37,687,505 (-)NCBIGRCr8
mRatBN7.21232,009,010 - 32,025,484 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,009,014 - 32,025,497 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1233,187,754 - 33,203,819 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01233,799,075 - 33,815,140 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01232,850,942 - 32,867,007 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01237,427,556 - 37,444,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1237,427,546 - 37,444,282 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01239,298,569 - 39,315,037 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,121,881 - 33,138,233 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11232,985,270 - 33,001,621 (-)NCBI
Celera1233,698,431 - 33,714,902 (-)NCBICelera
Cytogenetic Map12q15NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor. Egly JM and Coin F, DNA Repair (Amst). 2011 Jul 15;10(7):714-21. doi: 10.1016/j.dnarep.2011.04.021. Epub 2011 May 17.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8652557   PMID:9852112   PMID:12477932   PMID:27193682  


Genomics

Comparative Map Data
Gtf2h3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81237,669,995 - 37,687,505 (-)NCBIGRCr8
mRatBN7.21232,009,010 - 32,025,484 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,009,014 - 32,025,497 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1233,187,754 - 33,203,819 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01233,799,075 - 33,815,140 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01232,850,942 - 32,867,007 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01237,427,556 - 37,444,027 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1237,427,546 - 37,444,282 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01239,298,569 - 39,315,037 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,121,881 - 33,138,233 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11232,985,270 - 33,001,621 (-)NCBI
Celera1233,698,431 - 33,714,902 (-)NCBICelera
Cytogenetic Map12q15NCBI
GTF2H3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812123,633,829 - 123,662,604 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12123,633,739 - 123,662,604 (+)EnsemblGRCh38hg38GRCh38
GRCh3712124,118,376 - 124,147,151 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612122,684,334 - 122,711,287 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412122,643,260 - 122,670,214NCBI
Celera12123,714,817 - 123,741,772 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12121,079,532 - 121,108,395 (+)NCBIHuRef
CHM1_112123,939,235 - 123,968,101 (+)NCBICHM1_1
T2T-CHM13v2.012123,632,693 - 123,661,470 (+)NCBIT2T-CHM13v2.0
Gtf2h3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395124,717,211 - 124,735,743 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5124,717,203 - 124,735,743 (+)EnsemblGRCm39 Ensembl
GRCm385124,579,148 - 124,597,680 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5124,579,140 - 124,597,680 (+)EnsemblGRCm38mm10GRCm38
MGSCv375125,029,157 - 125,047,689 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365124,839,789 - 124,857,459 (+)NCBIMGSCv36mm8
Celera5121,655,848 - 121,674,546 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map563.67NCBI
Gtf2h3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554825,365,142 - 5,380,047 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554825,365,669 - 5,380,047 (-)NCBIChiLan1.0ChiLan1.0
GTF2H3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210131,708,349 - 131,737,682 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112131,704,710 - 131,734,059 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012121,218,813 - 121,246,807 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112125,445,381 - 125,473,763 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12125,445,381 - 125,473,763 (+)Ensemblpanpan1.1panPan2
GTF2H3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1265,985,094 - 6,011,253 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl265,985,798 - 6,011,163 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha266,147,525 - 6,174,121 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0266,234,737 - 6,261,341 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl266,234,495 - 6,261,295 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1266,168,228 - 6,194,816 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,260,228 - 6,287,181 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,213,786 - 6,240,388 (-)NCBIUU_Cfam_GSD_1.0
Gtf2h3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118158,283,347 - 158,304,710 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365581,173,064 - 1,196,063 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365581,176,154 - 1,196,028 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2H3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1429,335,582 - 29,355,435 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11429,335,715 - 29,355,465 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21431,029,684 - 31,047,752 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GTF2H3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111118,961,907 - 118,989,906 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11118,967,974 - 118,989,391 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037126,285,426 - 126,313,975 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf2h3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474723,422,319 - 23,435,926 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474723,422,289 - 23,437,193 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gtf2h3
172 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:133
Count of miRNA genes:98
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000001368
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598855Bp294Blood pressure QTL 2943.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12134851688Rat
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1300157Rf21Renal function QTL 214.4renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)12931821632103380Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
61421Cia12Collagen induced arthritis QTL 124.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121363552335682913Rat
631543Bp83Blood pressure QTL 835.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121555082638478808Rat
2293684Bmd26Bone mineral density QTL 264.40.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)121587265332974238Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
1298081Cia25Collagen induced arthritis QTL 254.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961088935682913Rat
70213Niddm27Non-insulin dependent diabetes mellitus QTL 273.72blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121983578938193007Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
70169Eae13Experimental allergic encephalomyelitis QTL 130.032nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)122413920236638073Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)122806443340130419Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)122806455740218380Rat
631829Alc6Alcohol consumption QTL 64.7consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)122860752637691617Rat

Markers in Region
RH134486  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21232,009,242 - 32,009,439 (+)MAPPERmRatBN7.2
Rnor_6.01237,427,789 - 37,427,985NCBIRnor6.0
Rnor_5.01239,298,802 - 39,298,998UniSTSRnor5.0
RGSC_v3.41233,122,114 - 33,122,310UniSTSRGSC3.4
Celera1233,698,664 - 33,698,860UniSTS
RH 3.4 Map12556.8UniSTS
Cytogenetic Map12q15UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 34 18 19 18 1 2 74 25 40 11 1
Low 17 23 23 23 7 9 10 1 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000001368   ⟹   ENSRNOP00000001368
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1232,009,014 - 32,025,497 (-)Ensembl
Rnor_6.0 Ensembl1237,427,546 - 37,444,282 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097451   ⟹   ENSRNOP00000097521
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1232,009,014 - 32,022,385 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112340   ⟹   ENSRNOP00000090533
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1232,009,014 - 32,022,319 (-)Ensembl
RefSeq Acc Id: NM_001024236   ⟹   NP_001019407
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81237,669,995 - 37,686,466 (-)NCBI
mRatBN7.21232,009,010 - 32,025,484 (-)NCBI
Rnor_6.01237,427,556 - 37,444,027 (-)NCBI
Rnor_5.01239,298,569 - 39,315,037 (-)NCBI
RGSC_v3.41233,121,881 - 33,138,233 (-)RGD
Celera1233,698,431 - 33,714,902 (-)RGD
Sequence:
RefSeq Acc Id: XM_063271173   ⟹   XP_063127243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81237,669,995 - 37,687,505 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001019407 (Get FASTA)   NCBI Sequence Viewer  
  XP_063127243 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH93380 (Get FASTA)   NCBI Sequence Viewer  
  EDM13571 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001368
  ENSRNOP00000001368.4
  ENSRNOP00000090533.1
  ENSRNOP00000097521.1
GenBank Protein Q561R7 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001019407   ⟸   NM_001024236
- UniProtKB: Q561R7 (UniProtKB/Swiss-Prot),   A6J0Y2 (UniProtKB/TrEMBL),   A0A8I6ASU2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000001368   ⟸   ENSRNOT00000001368
RefSeq Acc Id: ENSRNOP00000097521   ⟸   ENSRNOT00000097451
RefSeq Acc Id: ENSRNOP00000090533   ⟸   ENSRNOT00000112340
RefSeq Acc Id: XP_063127243   ⟸   XM_063271173
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q561R7-F1-model_v2 AlphaFold Q561R7 1-309 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698607
Promoter ID:EPDNEW_R9131
Type:multiple initiation site
Name:Gtf2h3_1
Description:general transcription factor IIH subunit 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01237,444,047 - 37,444,107EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305494 AgrOrtholog
BioCyc Gene G2FUF-19361 BioCyc
Ensembl Genes ENSRNOG00000001035 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001368 ENTREZGENE
  ENSRNOT00000001368.7 UniProtKB/Swiss-Prot
  ENSRNOT00000097451.1 UniProtKB/TrEMBL
  ENSRNOT00000112340.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7388486 IMAGE-MGC_LOAD
InterPro TFIIH_Tfb4/GTF2H3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:288651 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:112674 IMAGE-MGC_LOAD
NCBI Gene 288651 ENTREZGENE
PANTHER GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12831 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tfb4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gtf2h3 PhenoGen
RatGTEx ENSRNOG00000001035 RatGTEx
UniProt A0A8I6AA93_RAT UniProtKB/TrEMBL
  A0A8I6ASU2 ENTREZGENE, UniProtKB/TrEMBL
  A6J0Y2 ENTREZGENE, UniProtKB/TrEMBL
  Q561R7 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Gtf2h3  general transcription factor IIH subunit 3  Gtf2h3  general transcription factor IIH, polypeptide 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Gtf2h3  general transcription factor IIH, polypeptide 3  Gtf2h3_predicted  general transcription factor IIH, polypeptide 3 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Gtf2h3_predicted  general transcription factor IIH, polypeptide 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED