Cpsf7 (cleavage and polyadenylation specific factor 7)

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Gene: Cpsf7 (cleavage and polyadenylation specific factor 7) Rattus norvegicus

Analyze

Symbol:

Cpsf7

Name:

cleavage and polyadenylation specific factor 7

RGD ID:

1305441

Description:

Predicted to enable mRNA binding activity. Predicted to be involved in mRNA alternative polyadenylation; messenger ribonucleoprotein complex assembly; and protein heterotetramerization. Predicted to be located in cytoplasm and nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Orthologous to human CPSF7 (cleavage and polyadenylation specific factor 7); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; mRNA decay pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cleavage and polyadenylation specific factor 7, 59kDa; cleavage and polyadenylation specificity factor subunit 7; LOC365407; RGD1305441; similar to RIKEN cDNA 5730453I16

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	207,167,690 - 207,191,938 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	207,167,859 - 207,191,905 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	215,546,294 - 215,570,323 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	222,601,738 - 222,625,783 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	215,296,741 - 215,320,782 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	226,572,399 - 226,596,185 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	226,573,105 - 226,596,131 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	233,518,603 - 233,542,664 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	213,009,572 - 213,032,612 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	213,168,001 - 213,191,028 (+)	NCBI
Celera	1	204,662,017 - 204,685,057 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

intellectual disability (ISO)

Joubert syndrome 1 (ISO)

leukocyte adhesion deficiency 3 (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

atrazine (ISO)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbamazepine (ISO)

carnosic acid (ISO)

copper atom (EXP)

copper(0) (EXP)

coumarin (ISO)

dicrotophos (ISO)

diquat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

flusilazole (EXP)

gallic acid (ISO)

gentamycin (EXP)

glyphosate (EXP)

hydrogen peroxide (ISO)

inulin (ISO)

ivermectin (ISO)

perfluorooctane-1-sulfonic acid (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

thapsigargin (EXP)

triticonazole (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

messenger ribonucleoprotein complex assembly (IEA,ISO,ISS)

mRNA 3'-end processing (ISO)

mRNA alternative polyadenylation (IBA,IEA,ISO,ISS)

protein heterotetramerization (IEA,ISO,ISS)

protein tetramerization (ISO)

Cellular Component

cytoplasm (IEA,ISO,ISS)

mRNA cleavage and polyadenylation specificity factor complex (IBA,IEA,ISO)

mRNA cleavage factor complex (ISO,ISS)

nucleus (ISO,ISS)

Molecular Function

mRNA binding (IBA)

protein binding (ISO)

RNA binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

3'-end pre-mRNA processing pathway (ISO)

mRNA decay pathway (IEA)

RNA polymerase II transcription termination pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Pre-mRNA 3'-end processing complex assembly and function.	Chan S, etal., Wiley Interdiscip Rev RNA. 2011 May-Jun;2(3):321-35. doi: 10.1002/wrna.54. Epub 2010 Oct 18.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Means to an end: mechanisms of alternative polyadenylation of messenger RNA precursors.	Gruber AR, etal., Wiley Interdiscip Rev RNA. 2014 Mar-Apr;5(2):183-96. doi: 10.1002/wrna.1206. Epub 2013 Nov 14.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation
10.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:19864460	PMID:19946888	PMID:20695905	PMID:22658674	PMID:22681889	PMID:23187700	PMID:29276085	PMID:31505169

Genomics

Comparative Map Data

Cpsf7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	207,167,690 - 207,191,938 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	207,167,859 - 207,191,905 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	215,546,294 - 215,570,323 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	222,601,738 - 222,625,783 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	215,296,741 - 215,320,782 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	226,572,399 - 226,596,185 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	226,573,105 - 226,596,131 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	233,518,603 - 233,542,664 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	213,009,572 - 213,032,612 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	213,168,001 - 213,191,028 (+)	NCBI
Celera	1	204,662,017 - 204,685,057 (+)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

CPSF7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	61,402,729 - 61,429,975 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	61,402,641 - 61,430,031 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	61,170,201 - 61,197,447 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	60,926,777 - 60,953,849 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	58,505,642 - 58,532,986 (-)	NCBI		Celera
Cytogenetic Map	11	q12.2	NCBI
HuRef	11	57,498,010 - 57,525,354 (-)	NCBI		HuRef
CHM1_1	11	61,053,123 - 61,080,467 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	61,391,627 - 61,418,874 (-)	NCBI		T2T-CHM13v2.0

Cpsf7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	10,502,594 - 10,525,099 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	10,502,630 - 10,525,017 (+)	Ensembl		GRCm39 Ensembl
GRCm38	19	10,525,223 - 10,547,735 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	10,525,266 - 10,547,653 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	10,599,734 - 10,622,225 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	10,592,311 - 10,614,698 (+)	NCBI		MGSCv36	mm8
Celera	19	11,221,128 - 11,243,624 (+)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	6.6	NCBI

Cpsf7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955511	6,139,118 - 6,161,130 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955511	6,139,118 - 6,161,130 (+)	NCBI	ChiLan1.0	ChiLan1.0

CPSF7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	11	63,614,202 - 63,641,631 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	56,702,510 - 56,729,316 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	60,065,832 - 60,092,720 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	60,065,832 - 60,092,720 (-)	Ensembl	panpan1.1		panPan2

CPSF7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	18	54,986,709 - 55,012,499 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	18	54,986,810 - 55,009,382 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	53,559,662 - 53,585,514 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	56,034,104 - 56,060,195 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	56,034,171 - 56,058,185 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	55,092,629 - 55,118,450 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	54,714,618 - 54,740,435 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	55,594,658 - 55,620,764 (+)	NCBI		UU_Cfam_GSD_1.0

Cpsf7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	11,515,249 - 11,537,317 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936581	1,629,041 - 1,651,328 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936581	1,629,078 - 1,651,147 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CPSF7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	10,087,632 - 10,115,076 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	10,087,581 - 10,112,929 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	9,635,042 - 9,659,648 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CPSF7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	12,417,452 - 12,445,984 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	12,417,490 - 12,446,527 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	109,794,801 - 109,823,341 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cpsf7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624926	802,033 - 822,372 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cpsf7
81 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	905
Count of miRNA genes:	331
Interacting mature miRNAs:	426
Transcripts:	ENSRNOT00000028074
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
7394701	Uae46	Urinary albumin excretion QTL 46	3.6	0.0056	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	201554356	246554356	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat
1354624	Cm35	Cardiac mass QTL35	5.7		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	177227632	256448636	Rat
1358898	Bp255	Blood pressure QTL 255	3.6		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	191019702	246062233	Rat
1354646	Kidm18	Kidney mass QTL 18	5.7		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	151162512	256448636	Rat
1354652	Kidm20	Kidney mass QTL 20	4.3		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	1	177227632	256448636	Rat
6903303	Scl34	Serum cholesterol QTL 34	2.5	0.0033	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	180359209	218108781	Rat
738032	Hcas5	Hepatocarcinoma susceptibility QTL 5	3.12		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	176426412	257976495	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164747424	209747424	Rat
619613	Bp77	Blood pressure QTL 77		0.01	arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	164747424	209747424	Rat
8552891	Epfw5	Epididymal fat weight QTL 5	4.4		epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	1	193113876	238113876	Rat
2293654	Bss30	Bone structure and strength QTL 30	32.65	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	1	171629477	216629477	Rat
1357399	Bw45	Body weight QTL 45	3.05		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	1	206329708	251329708	Rat
1331790	Bp201	Blood pressure QTL 201	3.127		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	198211513	225126682	Rat
1549830	Bss1	Bone structure and strength QTL 1	4.8		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	172609619	217609619	Rat
7771612	Cm80	Cardiac mass QTL 80	8.4		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	1	149448574	221264292	Rat
61403	Niddm4	Non-insulin dependent diabetes mellitus QTL 4			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	206329708	222745518	Rat
2293693	Bss22	Bone structure and strength QTL 22	33.52	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	1	171629477	216629477	Rat
2293674	Bss39	Bone structure and strength QTL 39	7.1	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	1	201554356	246554356	Rat
631214	Bw61	Body weight QTL61	3.4	0.0001	intramuscular adipose amount (VT:0010044)	intramuscular fat area (CMO:0001162)	1	173108781	218108781	Rat
61341	Bp26	Blood pressure QTL 26			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	169537671	214537671	Rat
1600380	Niddm70	Non-insulin dependent diabetes mellitus QTL 70	3.1	0.0008	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	176550523	221550523	Rat
1600395	Niddm69	Non-insulin dependent diabetes mellitus QTL 69	4.14	0.0002	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	1	195804352	257091168	Rat
2293673	Bss27	Bone structure and strength QTL 27	18.63	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	1	171629477	216629477	Rat
1600374	Mcs17	Mammary carcinoma susceptibility QTL 17	3		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	197670404	242670404	Rat
1578778	Pur4	Proteinuria QTL 4	3.3	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	1	150700247	252085048	Rat
724559	Pancm1	Pancreatic morphology QTL 1	7.1		islet of Langerhans morphology trait (VT:0005215)	pancreatic islet damage composite score (CMO:0001156)	1	181759564	214537555	Rat
2312420	Pur17	Proteinuria QTL 17	7.1	0.0001	urine protein amount (VT:0005160)	urine total protein excretion rate (CMO:0000756)	1	156677124	218753816	Rat
2293694	Bss38	Bone structure and strength QTL 38	7.05	0.0001	femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	1	201554356	246554356	Rat
1600388	Niddm67	Non-insulin dependent diabetes mellitus QTL 67	5.84	0.000004	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
1600396	Niddm68	Non-insulin dependent diabetes mellitus QTL 68	4.97	0.0003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	195804352	257091168	Rat
2293655	Bss36	Bone structure and strength QTL 36	10.66	0.0001	femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	1	201554356	246554356	Rat
1578759	Uae30	Urinary albumin excretion QTL 30	3.3	0.003	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	150700247	252085048	Rat
1600397	Edcs4	Endometrial carcinoma susceptibility QTL 4	2.2		uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	1	206081677	251081677	Rat
2293677	Bss41	Bone structure and strength QTL 41	9.38	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	1	171629477	216629477	Rat
634321	Hc1	Hypercalciuria QTL 1	2.91		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	178810256	240830002	Rat
1300145	Rf7	Renal function QTL 7	2.96		urine creatinine amount (VT:0010540)	urine creatinine level (CMO:0000125)	1	185145134	221264292	Rat
10059590	Kidm44	Kidney mass QTL 44	3.42	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	191033875	236033875	Rat
1578763	Kidm29	Kidney mass QTL 29	3.3	0.0001	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	1	179567751	260522016	Rat
10059600	Bp378	Blood pressure QTL 378	3.08	0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	176869060	221869060	Rat
10059587	Bw173	Body weight QTL 173	3.23	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	1	202069611	247069611	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
2300175	Bmd40	Bone mineral density QTL 40	15.4	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	1	201554356	246554356	Rat
2300174	Bmd42	Bone mineral density QTL 42	8.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	bone mineral density (CMO:0001226)	1	171629477	216629477	Rat
2300187	Bmd41	Bone mineral density QTL 41	8.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
2300161	Bmd43	Bone mineral density QTL 43	8.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	171629477	216629477	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
1558658	Bw59	Body weight QTL 59	3.5	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	1	178784622	223784622	Rat
1302787	Stl25	Serum triglyceride level QTL 25	2.7	0.0073	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	1	180359209	210702199	Rat
1354653	Despr9	Despair related QTL 9		0.00019	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	167909849	212909849	Rat
724531	Uae5	Urinary albumin excretion QTL 5	4		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	1	150700142	252085212	Rat
1354661	Bw33	Body weight QTL 33	5.2		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
1354610	Bw34	Body weight QTL 34	4.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	151162512	256448636	Rat
737977	Bp160	Blood pressure QTL 160		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	181133855	226133855	Rat
631658	Cm7	Cardiac mass QTL 7	5.32	0.0001	aorta mass (VT:0002845)	aorta weight (CMO:0000076)	1	196248093	241248093	Rat
1358886	Bp260	Blood pressure QTL 260	3.67		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	151162766	225824951	Rat
634312	Bp143	Blood pressure QTL 143	3	0.0002	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	182623426	219932796	Rat
61376	Bp42	Blood pressure QTL 42	23.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	197814409	242814409	Rat
1549837	Hcar15	Hepatocarcinoma resistance QTL 15		0.05	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	153136852	260522016	Rat
70163	Bw20	Body weight QTL 20	5.1		body mass (VT:0001259)	body weight (CMO:0000012)	1	174133260	219133260	Rat
8655855	Arrd3	Age-related retinal degeneration QTL 3	3.07		lens clarity trait (VT:0001304)	cataract incidence/prevalence measurement (CMO:0001585)	1	183970203	243914901	Rat
8655655	Arrd2	Age-related retinal degeneration QTL 2	7.79		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	183970203	243914901	Rat
1357404	Bw42	Body weight QTL 42	4.49	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	1	206329708	251329708	Rat
1600363	Hc6	Hypercalciuria QTL 6	2.7		urine calcium amount (VT:0002985)	urine calcium excretion rate (CMO:0000763)	1	203995416	244113296	Rat
2293083	Iddm25	Insulin dependent diabetes mellitus QTL 25	4.18		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	181829673	224569684	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
634338	Hcar4	Hepatocarcinoma resistance QTL 4	4.6		liver integrity trait (VT:0010547)	liver tumorous lesion number to liver area ratio (CMO:0001210)	1	193422268	214537671	Rat
634313	Niddm43	Non-insulin dependent diabetes mellitus QTL 43			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	199050459	259647894	Rat
2312564	Glom18	Glomerulus QTL 18	2.4	0.003	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	1	185356336	231689108	Rat
2292218	Kidm35	Kidney mass QTL 35			kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	199368955	224569684	Rat
2292220	Bp306	Blood pressure QTL 306	3.47	0.00087	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	243914901	Rat
2292222	Bp307	Blood pressure QTL 307	3.06	0.0014	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	164310393	213533942	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
631838	Niddm36	Non-insulin dependent diabetes mellitus QTL 36		0.01	insulin secretion trait (VT:0003564)	calculated pancreatic islet insulin release measurement (CMO:0001217)	1	184550676	229550676	Rat
1358191	Ept10	Estrogen-induced pituitary tumorigenesis QTL 10	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	192825253	243914732	Rat
2302375	Bw83	Body weight QTL 83	4.87	0.0002	body mass (VT:0001259)	body weight (CMO:0000012)	1	197697768	242697768	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
1582206	Kidm33	Kidney mass QTL 33	6.9		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	1	188377360	224054420	Rat
724562	Rends1	Renal damage susceptibility QTL 1		0.05	kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	1	169537671	214537671	Rat
1354580	Scort1	Serum corticosterone level QTL 1	3.4		blood corticosterone amount (VT:0005345)	blood corticosterone level (CMO:0001172)	1	156677124	256448636	Rat
2293689	Bss47	Bone structure and strength QTL 47	7.25	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	1	171629477	216629477	Rat
1357335	Bw39	Body weight QTL 39	3.3		body mass (VT:0001259)	body weight (CMO:0000012)	1	197814409	242814409	Rat
1358294	Bw37	Body weight QTL 37	5	0.000011	body mass (VT:0001259)	body weight (CMO:0000012)	1	171310381	216310381	Rat
1641926	Teswt2	Testicular weight QTL 2	2.82		testis mass (VT:1000644)	both testes wet weight (CMO:0000175)	1	197697768	238755659	Rat
1298084	Thym4	Thymus enlargement QTL 4	10.68		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	197814409	242814409	Rat
1358292	Cm37	Cardiac mass QTL 37	6.2	0.00000081	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	1	196248093	241248093	Rat

Markers in Region

RH142902

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	207,183,794 - 207,183,909 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	226,588,339 - 226,588,453	NCBI	Rnor6.0
Rnor_5.0	1	233,534,594 - 233,534,708	UniSTS	Rnor5.0
RGSC_v3.4	7	139,916,134 - 139,916,248	UniSTS	RGSC3.4
RGSC_v3.4	1	213,024,806 - 213,024,920	UniSTS	RGSC3.4
Celera	1	204,677,251 - 204,677,365	UniSTS
RH 3.4 Map	1	1510.2	UniSTS
Cytogenetic Map	1	q43	UniSTS
Cytogenetic Map	7	q35	UniSTS

RH139325

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	207,183,793 - 207,183,924 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	226,588,338 - 226,588,468	NCBI	Rnor6.0
Rnor_5.0	1	233,534,593 - 233,534,723	UniSTS	Rnor5.0
RGSC_v3.4	7	139,916,133 - 139,916,263	UniSTS	RGSC3.4
RGSC_v3.4	1	213,024,805 - 213,024,935	UniSTS	RGSC3.4
Celera	1	204,677,250 - 204,677,380	UniSTS
Cytogenetic Map	1	q43	UniSTS
Cytogenetic Map	7	q35	UniSTS

RH140202

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	207,191,213 - 207,191,395 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	226,595,758 - 226,595,939	NCBI	Rnor6.0
Rnor_5.0	1	233,542,013 - 233,542,194	UniSTS	Rnor5.0
RGSC_v3.4	1	213,032,225 - 213,032,406	UniSTS	RGSC3.4
Celera	1	204,684,670 - 204,684,851	UniSTS
RH 3.4 Map	1	1510.5	UniSTS
Cytogenetic Map	1	q43	UniSTS

AW521848

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	207,167,685 - 207,167,836 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	226,572,291 - 226,572,441	NCBI	Rnor6.0
Rnor_5.0	1	233,518,487 - 233,518,637	UniSTS	Rnor5.0
RGSC_v3.4	1	213,008,699 - 213,008,849	UniSTS	RGSC3.4
Celera	1	204,661,144 - 204,661,294	UniSTS
RH 3.4 Map	1	1510.3	UniSTS
Cytogenetic Map	1	q43	UniSTS

UniSTS:478984

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	207,189,926 - 207,190,468 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	226,594,471 - 226,595,012	NCBI	Rnor6.0
Rnor_5.0	1	233,540,726 - 233,541,267	UniSTS	Rnor5.0
RGSC_v3.4	1	213,030,938 - 213,031,479	UniSTS	RGSC3.4
Celera	1	204,683,383 - 204,683,924	UniSTS
Cytogenetic Map	1	q43	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	41	57	41	19	41	6	8	74	35	41	11	6
Low		2					2	3					2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014245	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001399757	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760238	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760239	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760240	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085585	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085595	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085601	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005489751	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC095662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC083864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473953	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000046	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000028074 ⟹ ENSRNOP00000028074

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	207,167,859 - 207,191,905 (+)	Ensembl
Rnor_6.0 Ensembl	1	226,573,105 - 226,596,131 (+)	Ensembl

RefSeq Acc Id:

NM_001014245 ⟹ NP_001014267

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,167,866 - 207,191,938 (+)	NCBI
Rnor_6.0	1	226,573,105 - 226,596,145 (+)	NCBI
Rnor_5.0	1	233,518,603 - 233,542,664 (+)	NCBI
RGSC_v3.4	1	213,009,572 - 213,032,612 (+)	RGD
Celera	1	204,662,017 - 204,685,057 (+)	RGD

Sequence:

show sequence

GTGGCATCTTTCTTACTTTGTCCGTTCTCCGGGCTCGAGAGCGTGTTTCCGGAGCCATGTCAGA
AGGAGTGGATTTGATTGATATATACGCTGATGAAGAGTTCAATCAGGACTCGGAGTTCAACAAC
ACAGATCAGATTGACCTATATGATGATGTGCTGACGGCGGCCTCACAGCCCTCGGATGACAGAA
GCAGTAGCACAGAACCACCCCCTCCTGTCCGCCAGGAGCCAGCTCCCAAACCAAACAACAAGAC
CCCTGCAATTCTGTACACATACAGTGGCCTGCGGAGTCGGCGAGCAGCTGTCTATGTAGGCAGT
TTCTCCTGGTGGACCACAGACCAGCAGCTGATCCAGGTTATTCGCTCTATAGGAGTCTATGATG
TGGTGGAGTTGAAATTTGCAGAGAACCGTGCAAATGGCCAGTCTAAAGGGTATGCTGAGGTGGT
GGTAGCCTCTGAAAATTCTGTCCACAAATTGCTGGAACTCTTACCAGGAAAAGTTCTTAATGGA
GAAAAAGTAGATGTGAGGCCAGCCACTCGGCAGAACTTATCACAATTTGAGGCTCAGGCTCGGA
AACGAATACCTCCACGGGCCCACTCCCGAGATTCTAGTGATTCTGCTGATGGACGGGCAACCCC
CTCTGAGAATCTTGTACCCTCATCTGCTCGTGTGGATAAGCCCCCCAGCGTGTTGCCCTACTTT
AACCGTCCTCCTTCAGCCCTTCCCCTAATGGGTCTGCCCCCACCCCCAATTCCACCCCCACCAC
CTCTCTCCTCAAGCTTTGGTGTCCCTCCTCCTCCTCCTGGTATCCACTACCAGCATCTCATGCC
CCCCCCTCCTCGATTACCTCCTCATCTGGCTGTACCTCCCCCTGGGGCCATCCCACCAGCCCTT
CACCTCAATCCAGCCTTCTTCCCCCCACCAAATGCTACAGTGGGGCCTCCACCAGATACTTACA
TGAAGGCCTCTACACCCTATAACCACCATGGCAGCCGAGATTCAGGCCCTCTACCGTCTACAGT
GAGTGAAGCTGAATTTGAAGAGATAATGAAGCGAAACAGAGCAATTTCCAGCAGTGCCATTTCC
AAAGCAGTGTCTGGAGCTAGTGCAGGGGATTACAGTGACGCCATTGAGACACTACTCACAGCCA
TTGCAGTTATCAAACAGTCCCGAGTCGCCAATGATGAGCGTTGTCGGGTCCTCATCTCTTCACT
TAAGGACTGTCTTCATGGCATAGAGGCCAAGTCTTACAGTGTGGGTGCCAGTGGAAGCTCTTCT
AGGAAAAGACATCGGTCAAGGGAGAGGTCACCCAGCCGGTCCCGAGAGAGTAGCAGAAGGCACC
GAGACTTGCTTCATAATGAAGACCGACATGATGATTATTTCCAAGAAAGGAACCGGGAGCATGA
GAGACACCGGGATAGAGAACGGGACCGGCACCACTGAGAAAGGAGTCTGGGTGGAAGCAAATTG
TTTTTAATGGACTTGCATCTCCTCACCTTGATCAGGACTAAAGGACGGAGGCCGCTCCACCCCT
TCCCCTTCTTCCAAACCCCTAACTTCCTCCAGGCAAAACCCTCTGCCCTGCAGGATTGAAGATG
GCTTGGCAGCCCTCCCAATCCCACACCTTCTGTTTGCCATGGGGGAAGAACCTAAAGACTTGCT
GGGGTAGTGAACGAGGGCATACAGGAAGACAGCAACATGTCCAGCCCATAGTCTCCATAGAGAA
TGGTGCTTTGTCCAAGGAAACCTGAGTTTCTGATTGCCCAGAAGCAGTCAGTGGTGAGGTTACT
ATGAGAAAATTTCCTTCCCAGAGAAAATGGATCCTCTATGTGGGGTCTTAGGAAAGTGACTGGG
TGTGCCAAAAATGCCCAGGGTTCTGCCCTCAGTACTAGATTTGATGGGGCCAAAAGGGTCCAAA
CCCTGCTAACATACCACTTTGTTCAACTCCTGTACTTTCCTAGCCAGTTGAGGAGGGACCATGA
GAACAGAAACTACCTTGTGACAAGAAACGTGTTCTCAGTTTTCTCCTCACGTGTTGATGGTTTA
TTTCCATGGCCTCCTAGAGGGCTGAATCCTTTTGACTCCTTACTATCTGACTCCTCAGTGGACT
TGCCCCTCTGAAACAGAACCCAGGAAGCTTCGGCTATCTGCCGGAAGCCTAGGCCAGCCAGATA
CCACCATTTGCTGCTTTAGGCTTGTCTGTTTGTTGCAATAACCAGCTCTTAGGTATTTCCTTTC
CCCAAGGCTTTCCATTTAACATGGAATCCTTCCCCAAGAAGGCTTCTTCCTTGTTTTAGAGGAA
GGTACTGCCTTTGGGACTTAGGGATGTCATGGGACCTCAGTAACTAGGACCCCTAGTTAATAAA
GTACCAGAAGTGTGGAGAAGAGAGCAATTTGAGCAGTATGTAGCCTACTCACATGGGCTCTTTT
GCAGGTTAATGTGAGCATAGGCTTGCATTTCCAAGGTACATACTTTGACTTAACTGTGGAATAA
CTCAGCACTAATAGGCAGGTAAAGTCAAGACTGGTTTTTGGGGGTTTCTTTTTTGGTGTTTTTG
TTTTTGTTTTTATTCCTTTGCTCTGATACTTCCCCCGTCACTTTGCCTGGAGGTGCTTCCAGCC
TTTAAGAAGGAGCAGAGAATTGGAGCTCAGAGTTGTAAGGACCAGCACACTAGTGGCCATTTTC
TGCACAAGCAAATGGAATTGCTTTTTTCAGCATCCAGACTGTGATAGGTTGCTCTTGATGGAGG
TAGCCACAGTCCTGGAGTACCATAGGGTAATGTTCCTTCAGCAGGGCCTGTGAGATCTAATGTG
AAGAGAGACACAACATGTGAGATGGGACTTGGTGTGTGAGGCATGGAGTCATTGGAGACTCTTC
AGATTCAGAGGGGAGACTGAATTGGATGCTTTCTCTCTTCTCGGCACACTTCTGACAGACCCCT
TCAGTCACTGAGGGAGTGCCCCCAAGGTTGGAGAGGCACATTCCCTTTGGACAGAGGCTACAAG
TTGTAGCTTATTTTCCTGTCCCCTAAACCAATCCCTATTCCATCAACATGGCATCCTGCCTAAT
TTTCTAAGGGTTAAGTGATATGCTTATTCTTGAAAGCAACTCGGGTGTCTTTTTAAAAAAGAAA
AAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001399757 ⟹ NP_001386686

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,167,866 - 207,191,938 (+)	NCBI

RefSeq Acc Id:

XM_006231061 ⟹ XP_006231123

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,167,846 - 207,191,865 (+)	NCBI
Rnor_6.0	1	226,572,451 - 226,596,185 (+)	NCBI
Rnor_5.0	1	233,518,603 - 233,542,664 (+)	NCBI

Sequence:

show sequence

GGGGGGGCGGGACCTGGGGCGGAGAGCGGTTCGCGCGCTTCGGGCCTAGTCGGGACTCTCCGCG
GCCGCCGCCATATTCCCGTGGCATCTTTCTTACTTTGTCCGTTCTCCGGGCTCGAGAGCGTGTT
TCCGGAGCCATGTCAGAAGGAGTGGATTTGATTGATATATACGCTGATGAAGAGTTCAATCAGG
ACTCGGAGTTCAACAACACAGATCAGATTGACCTATATGATGATGTGCTGACGGCGGCCTCACA
GCCCTCGGATGACAGAAGCAGTAGCACAGAACCACCCCCTCCTGTCCGCCAGGAGCCAGCTCCC
AAACCAAACAACAAGACCCCTGCAATTCTGTACACATACAGTGGCCTGCGGAGTCGGCGAGCAG
CTGTCTATGTAGGCAGTTTCTCCTGGGGTCATCTATGGGACGAGATATCAGAGTGAACACCTTG
AACTCTTGGTGGTCATTAGATGGTCCTGTGATAATGTGGACCACAGACCAGCAGCTGATCCAGG
TTATTCGCTCTATAGGAGTCTATGATGTGGTGGAGTTGAAATTTGCAGAGAACCGTGCAAATGG
CCAGTCTAAAGGGTATGCTGAGGTGGTGGTAGCCTCTGAAAATTCTGTCCACAAATTGCTGGAA
CTCTTACCAGGAAAAGTTCTTAATGGAGAAAAAGTAGATGTGAGGCCAGCCACTCGGCAGAACT
TATCACAATTTGAGGCTCAGGCTCGGAAACGTGAGTGCGTCCGAGTCCCAAGAGGGGGAATACC
TCCACGGGCCCACTCCCGAGATTCTAGTGATTCTGCTGATGGACGGGCAACCCCCTCTGAGAAT
CTTGTACCCTCATCTGCTCGTGTGGATAAGCCCCCCAGCGTGTTGCCCTACTTTAACCGTCCTC
CTTCAGCCCTTCCCCTAATGGGTCTGCCCCCACCCCCAATTCCACCCCCACCACCTCTCTCCTC
AAGCTTTGGTGTCCCTCCTCCTCCTCCTGGTATCCACTACCAGCATCTCATGCCCCCCCCTCCT
CGATTACCTCCTCATCTGGCTGTACCTCCCCCTGGGGCCATCCCACCAGCCCTTCACCTCAATC
CAGCCTTCTTCCCCCCACCAAATGCTACAGTGGGGCCTCCACCAGATACTTACATGAAGGCCTC
TACACCCTATAACCACCATGGCAGCCGAGATTCAGGCCCTCTACCGTCTACAGTGAGTGAAGCT
GAATTTGAAGAGATAATGAAGCGAAACAGAGCAATTTCCAGCAGTGCCATTTCCAAAGCAGTGT
CTGGAGCTAGTGCAGGGGATTACAGTGACGCCATTGAGACACTACTCACAGCCATTGCAGTTAT
CAAACAGTCCCGAGTCGCCAATGATGAGCGTTGTCGGGTCCTCATCTCTTCACTTAAGGACTGT
CTTCATGGCATAGAGGCCAAGTCTTACAGTGTGGGTGCCAGTGGAAGCTCTTCTAGGAAAAGAC
ATCGGTCAAGGGAGAGGTCACCCAGCCGGTCCCGAGAGAGTAGCAGAAGGCACCGAGACTTGCT
TCATAATGAAGACCGACATGATGATTATTTCCAAGAAAGGAACCGGGAGCATGAGAGACACCGG
GATAGAGAACGGGACCGGCACCACTGAGAAAGGAGTCTGGGTGGAAGCAAATTGTTTTTAATGG
ACTTGCATCTCCTCACCTTGATCAGGACTAAAGGACGGAGGCCGCTCCACCCCTTCCCCTTCTT
CCAAACCCCTAACTTCCTCCAGGCAAAACCCTCTGCCCTGCAGGATTGAAGATGGCTTGGCAGC
CCTCCCAATCCCACACCTTCTGTTTGCCATGGGGGAAGAACCTAAAGACTTGCTGGGGTAGTGA
ACGAGGGCATACAGGAAGACAGCAACATGTCCAGCCCATAGTCTCCATAGAGAATGGTGCTTTG
TCCAAGGAAACCTGAGTTTCTGATTGCCCAGAAGCAGTCAGTGGTGAGGTTACTATGAGAAAAT
TTCCTTCCCAGAGAAAATGGATCCTCTATGTGGGGTCTTAGGAAAGTGACTGGGTGTGCCAAAA
ATGCCCAGGGTTCTGCCCTCAGTACTAGATTTGATGGGGCCAAAAGGGTCCAAACCCTGCTAAC
ATACCACTTTGTTCAACTCCTGTACTTTCCTAGCCAGTTGAGGAGGGACCATGAGAACAGAAAC
TACCTTGTGACAAGAAACGTGTTCTCAGTTTTCTCCTCACGTGTTGATGGTTTATTTCCATGGC
CTCCTAGAGGGCTGAATCCTTTTGACTCCTTACTATCTGACTCCTCAGTGGACTTGCCCCTCTG
AAACAGAACCCAGGAAGCTTCGGCTATCTGCCGGAAGCCTAGGCCAGCCAGATACCACCATTTG
CTGCTTTAGGCTTGTCTGTTTGTTGCAATAACCAGCTCTTAGGTATTTCCTTTCCCCAAGGCTT
TCCATTTAACATGGAATCCTTCCCCAAGAAGGCTTCTTCCTTGTTTTAGAGGAAGGTACTGCCT
TTGGGACTTAGGGATGTCATGGGACCTCAGTAACTAGGACCCCTAGTTAATAAAGTACCAGAAG
TGTGGAGAAGAGAGCAATTTGAGCAGTATGTAGCCTACTCACATGGGCTCTTTTGCAGGTTAAT
GTGAGCATAGGCTTGCATTTCCAAGGTACATACTTTGACTTAACTGTGGAATAACTCAGCACTA
ATAGGCAGGTAAAGTCAAGACTGGTTTTTGGGGGTTTCTTTTTTGGTGTTTTTGTTTTTGTTTT
TATTCCTTTGCTCTGATACTTCCCCCGTCACTTTGCCTGGAGGTGCTTCCAGCCTTTAAGAAGG
AGCAGAGAATTGGAGCTCAGAGTTGTAAGGACCAGCACACTAGTGGCCATTTTCTGCACAAGCA
AATGGAATTGCTTTTTTCAGCATCCAGACTGTGATAGGTTGCTCTTGATGGAGGTAGCCACAGT
CCTGGAGTACCATAGGGTAATGTTCCTTCAGCAGGGCCTGTGAGATCTAATGTGAAGAGAGACA
CAACATGTGAGATGGGACTTGGTGTGTGAGGCATGGAGTCATTGGAGACTCTTCAGATTCAGAG
GGGAGACTGAATTGGATGCTTTCTCTCTTCTCGGCACACTTCTGACAGACCCCTTCAGTCACTG
AGGGAGTGCCCCCAAGGTTGGAGAGGCACATTCCCTTTGGACAGAGGCTACAAGTTGTAGCTTA
TTTTCCTGTCCCCTAAACCAATCCCTATTCCATCAACATGGCATCCTGCCTAATTTTCTAAGGG
TTAAGTGATATGCTTATTCTTGAAAGCAACTCGGGTGTCTTTTTAAAAAAGAAAAAAATGAAAA
AAAAAAAAAAAGGAAAGTGACAGTTAAGGAAAAA

hide sequence

RefSeq Acc Id:

XM_039085585 ⟹ XP_038941513

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,167,979 - 207,191,865 (+)	NCBI

RefSeq Acc Id:

XM_039085595 ⟹ XP_038941523

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,167,690 - 207,191,865 (+)	NCBI

RefSeq Acc Id:

XM_039085601 ⟹ XP_038941529

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,167,975 - 207,183,620 (+)	NCBI

RefSeq Acc Id:

XM_039085607 ⟹ XP_038941535

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,174,523 - 207,191,865 (+)	NCBI

RefSeq Acc Id:

XM_039085608 ⟹ XP_038941536

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,167,980 - 207,191,865 (+)	NCBI

RefSeq Acc Id:

XM_039085610 ⟹ XP_038941538

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,174,523 - 207,191,865 (+)	NCBI

RefSeq Acc Id:

XR_005489751

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	207,167,978 - 207,191,865 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014267	(Get FASTA)	NCBI Sequence Viewer
	NP_001386686	(Get FASTA)	NCBI Sequence Viewer
	XP_006231123	(Get FASTA)	NCBI Sequence Viewer
	XP_038941513	(Get FASTA)	NCBI Sequence Viewer
	XP_038941523	(Get FASTA)	NCBI Sequence Viewer
	XP_038941529	(Get FASTA)	NCBI Sequence Viewer
	XP_038941535	(Get FASTA)	NCBI Sequence Viewer
	XP_038941536	(Get FASTA)	NCBI Sequence Viewer
	XP_038941538	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83864	(Get FASTA)	NCBI Sequence Viewer
	EDM12817	(Get FASTA)	NCBI Sequence Viewer
	Q5XI29	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001014267 ⟸ NM_001014245
- Peptide Label:	isoform 2
- UniProtKB:	Q5XI29 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MSEGVDLIDIYADEEFNQDSEFNNTDQIDLYDDVLTAASQPSDDRSSSTEPPPPVRQEPAPKPN NKTPAILYTYSGLRSRRAAVYVGSFSWWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYA EVVVASENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRIPPRAHSRDSSDSADGR ATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGIHYQH LMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASTPYNHHGSRDSGPLP STVSEAEFEEIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERCRVLI SSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQERNR EHERHRDRERDRHH hide sequence

RefSeq Acc Id:

XP_006231123 ⟸ XM_006231061

- Peptide Label:

isoform X3

- Sequence:

show sequence

MGRDIRVNTLNSWWSLDGPVIMWTTDQQLIQVIRSIGVYDVVELKFAENRANGQSKGYAEVVVA
SENSVHKLLELLPGKVLNGEKVDVRPATRQNLSQFEAQARKRECVRVPRGGIPPRAHSRDSSDS
ADGRATPSENLVPSSARVDKPPSVLPYFNRPPSALPLMGLPPPPIPPPPPLSSSFGVPPPPPGI
HYQHLMPPPPRLPPHLAVPPPGAIPPALHLNPAFFPPPNATVGPPPDTYMKASTPYNHHGSRDS
GPLPSTVSEAEFEEIMKRNRAISSSAISKAVSGASAGDYSDAIETLLTAIAVIKQSRVANDERC
RVLISSLKDCLHGIEAKSYSVGASGSSSRKRHRSRERSPSRSRESSRRHRDLLHNEDRHDDYFQ
ERNREHERHRDRERDRHH

hide sequence

RefSeq Acc Id:

ENSRNOP00000028074 ⟸ ENSRNOT00000028074

RefSeq Acc Id:	XP_038941523 ⟸ XM_039085595
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QG69 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038941529 ⟸ XM_039085601
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038941513 ⟸ XM_039085585
- Peptide Label:	isoform X1
- UniProtKB:	A0A8L2QG69 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038941536 ⟸ XM_039085608
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038941538 ⟸ XM_039085610
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038941535 ⟸ XM_039085607
- Peptide Label:	isoform X3

RefSeq Acc Id:	NP_001386686 ⟸ NM_001399757
- Peptide Label:	isoform 1
- UniProtKB:	A0A8L2QG69 (UniProtKB/TrEMBL)

Protein Domains

RRM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XI29-F1-model_v2	AlphaFold	Q5XI29	1-462	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305441	AgrOrtholog
BioCyc Gene	G2FUF-56427	BioCyc
Ensembl Genes	ENSRNOG00000020668	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000028074	ENTREZGENE
	ENSRNOP00000028074.6	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000028074	ENTREZGENE
	ENSRNOT00000028074.6	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7127736	IMAGE-MGC_LOAD
InterPro	CPSF6/7	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	CPSF7_RRM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Nucleotide-bd_a/b_plait_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RRM_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:365407	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:95116	IMAGE-MGC_LOAD
NCBI Gene	365407	ENTREZGENE
PANTHER	PTHR23204	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR23204:SF2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Cpsf7	PhenoGen
PROSITE	RRM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	RRM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8L2QG69	ENTREZGENE, UniProtKB/TrEMBL
	CPSF7_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-04-27	Cpsf7	cleavage and polyadenylation specific factor 7	Cpsf7	cleavage and polyadenylation specific factor 7, 59kDa	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2009-06-12	Cpsf7	cleavage and polyadenylation specific factor 7, 59kDa	RGD1305441	similar to RIKEN cDNA 5730453I16	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1305441	similar to RIKEN cDNA 5730453I16	RGD1305441_predicted	similar to RIKEN cDNA 5730453I16 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1305441_predicted	similar to RIKEN cDNA 5730453I16 (predicted)	LOC365407_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC365407_predicted	similar to RIKEN cDNA 5730453I16 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)