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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Cntrl | Rat | (-)-epigallocatechin 3-gallate | increases expression | ISO | CNTRL (Homo sapiens) | 6480464 | epigallocatechin gallate results in increased expression of CNTRL protein | CTD | PMID:31195006 | Cntrl | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Cntrl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CNTRL mRNA | CTD | PMID:36331819 | Cntrl | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of CNTRL mRNA | CTD | PMID:22206623 | Cntrl | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of CNTRL mRNA | CTD | PMID:29097150 | Cntrl | Rat | 17beta-estradiol | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | Estradiol results in decreased expression of CNTRL mRNA | CTD | PMID:39298647 | Cntrl | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | Cntrl (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Cntrl | Rat | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | ISO | Cntrl (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Cntrl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CNTRL mRNA | CTD | PMID:19933214 | Cntrl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CNTRL mRNA | CTD | PMID:33387578 | Cntrl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of CNTRL mRNA | CTD | PMID:34747641 | Cntrl | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Cntrl (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of CNTRL mRNA | CTD | PMID:25975270 | Cntrl | Rat | 5-aza-2'-deoxycytidine | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | TP53 protein affects the reaction [Decitabine results in decreased expression of CNTRL mRNA] | CTD | PMID:19363521 | Cntrl | Rat | 5-aza-2'-deoxycytidine | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Decitabine results in decreased expression of CNTRL mRNA | CTD | PMID:19363521 | Cntrl | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of CNTRL mRNA | CTD | PMID:30047161 | Cntrl | Rat | acrolein | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of CNTRL mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | Cntrl | Rat | alpha-pinene | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of CNTRL mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of CNTRL mRNA | CTD | PMID:32699268 | Cntrl | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of CNTRL mRNA | CTD | PMID:30047161 | Cntrl | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of CNTRL gene | CTD | PMID:28931070 | Cntrl | Rat | Benzo[k]fluoranthene | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | benzo(k)fluoranthene results in decreased expression of CNTRL mRNA | CTD | PMID:26377693 | Cntrl | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of CNTRL mRNA | CTD | PMID:34319233 | Cntrl | Rat | bisphenol A | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | bisphenol A results in increased expression of CNTRL mRNA | CTD | PMID:26063408 | Cntrl | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CNTRL mRNA | CTD | PMID:32145629 and PMID:32528016 | Cntrl | Rat | bisphenol A | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of CNTRL protein | CTD | PMID:33376534 | Cntrl | Rat | bisphenol A | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | bisphenol A results in decreased expression of CNTRL mRNA | CTD | PMID:32156529 and PMID:33221593 | Cntrl | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CNTRL mRNA | CTD | PMID:29097150 | Cntrl | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CNTRL mRNA | CTD | PMID:30816183 | Cntrl | Rat | butanal | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of CNTRL mRNA | CTD | PMID:26079696 | Cntrl | Rat | cadmium atom | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CNTRL mRNA | CTD | PMID:35301059 | Cntrl | Rat | cadmium dichloride | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CNTRL mRNA | CTD | PMID:35301059 | Cntrl | Rat | carbon nanotube | affects expression | ISO | Cntrl (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of CNTRL mRNA | CTD | PMID:25620056 | Cntrl | Rat | CGP 52608 | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CNTRL gene] | CTD | PMID:28238834 | Cntrl | Rat | chlorpyrifos | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of CNTRL mRNA | CTD | PMID:37019170 | Cntrl | Rat | ciguatoxin CTX1B | affects expression | ISO | Cntrl (Mus musculus) | 6480464 | Ciguatoxins affects the expression of CNTRL mRNA | CTD | PMID:18353800 | Cntrl | Rat | cisplatin | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of CNTRL mRNA | CTD | PMID:27392435 | Cntrl | Rat | clofibrate | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | Clofibrate results in increased expression of CNTRL mRNA | CTD | PMID:17585979 and PMID:23811191 | Cntrl | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of CNTRL mRNA | CTD | PMID:24386269 | Cntrl | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of CNTRL mRNA | CTD | PMID:26577399 | Cntrl | Rat | cyclosporin A | increases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of CNTRL mRNA | CTD | PMID:25562108 | Cntrl | Rat | cytarabine | increases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Cytarabine results in increased expression of CNTRL mRNA | CTD | PMID:21198554 | Cntrl | Rat | DDE | increases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of CNTRL mRNA | CTD | PMID:38568856 | Cntrl | Rat | dibenzo[a,l]pyrene | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | dibenzo(a and l)pyrene results in increased expression of CNTRL mRNA | CTD | PMID:25908611 | Cntrl | Rat | Dibutyl phosphate | affects expression | ISO | CNTRL (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of CNTRL mRNA | CTD | PMID:37042841 | Cntrl | Rat | dibutyl phthalate | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of CNTRL mRNA | CTD | PMID:17361019 | Cntrl | Rat | diuron | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Diuron results in decreased expression of CNTRL mRNA | CTD | PMID:35967413 | Cntrl | Rat | dorsomorphin | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Cntrl | Rat | doxorubicin | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | Doxorubicin results in increased expression of CNTRL mRNA | CTD | PMID:25896364 | Cntrl | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of CNTRL mRNA | CTD | PMID:29391264 | Cntrl | Rat | entinostat | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | entinostat results in decreased expression of CNTRL mRNA | CTD | PMID:27188386 | Cntrl | Rat | lead(0) | affects expression | ISO | CNTRL (Homo sapiens) | 6480464 | Lead affects the expression of CNTRL mRNA | CTD | PMID:28903495 | Cntrl | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of CNTRL mRNA | CTD | PMID:30047161 | Cntrl | Rat | methyl methanesulfonate | increases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of CNTRL mRNA | CTD | PMID:23649840 | Cntrl | Rat | mono(2-ethylhexyl) phthalate | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of CNTRL mRNA | CTD | PMID:22401849 | Cntrl | Rat | nitrates | multiple interactions | ISO | Cntrl (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of CNTRL mRNA | CTD | PMID:35964746 | Cntrl | Rat | ozone | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of CNTRL mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | Cntrl | Rat | paracetamol | affects expression | ISO | Cntrl (Mus musculus) | 6480464 | Acetaminophen affects the expression of CNTRL mRNA | CTD | PMID:17562736 | Cntrl | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of CNTRL mRNA | CTD | PMID:33387578 | Cntrl | Rat | PCB138 | multiple interactions | ISO | Cntrl (Mus musculus) | 6480464 | [2 more ... | CTD | PMID:25510870 | Cntrl | Rat | pentanal | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | pentanal results in decreased expression of CNTRL mRNA | CTD | PMID:26079696 | Cntrl | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of CNTRL mRNA | CTD | PMID:27153767 | Cntrl | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Cntrl (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CNTRL mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of CNTRL mRNA | CTD | PMID:36331819 | Cntrl | Rat | phenylmercury acetate | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of CNTRL mRNA | CTD | PMID:26272509 | Cntrl | Rat | phenylmercury acetate | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CNTRL mRNA | CTD | PMID:27188386 | Cntrl | Rat | pirinixic acid | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | pirinixic acid results in increased expression of CNTRL mRNA | CTD | PMID:18301758 | Cntrl | Rat | pirinixic acid | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of CNTRL mRNA | CTD | PMID:23811191 | Cntrl | Rat | potassium dichromate | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of CNTRL mRNA | CTD | PMID:23608068 | Cntrl | Rat | quercetin | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Quercetin results in decreased expression of CNTRL mRNA | CTD | PMID:21632981 | Cntrl | Rat | resveratrol | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of CNTRL mRNA | CTD | PMID:23557933 | Cntrl | Rat | SB 431542 | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Cntrl | Rat | senecionine | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | senecionine results in decreased expression of CNTRL protein | CTD | PMID:35357534 | Cntrl | Rat | silver atom | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | Silver results in decreased expression of CNTRL mRNA | CTD | PMID:27131904 | Cntrl | Rat | silver(0) | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | Silver results in decreased expression of CNTRL mRNA | CTD | PMID:27131904 | Cntrl | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of CNTRL mRNA | CTD | PMID:30047161 | Cntrl | Rat | sunitinib | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of CNTRL mRNA | CTD | PMID:31533062 | Cntrl | Rat | tetraphene | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | benz(a)anthracene results in increased expression of CNTRL mRNA | CTD | PMID:26377693 | Cntrl | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of CNTRL mRNA | CTD | PMID:34492290 | Cntrl | Rat | thiram | increases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Thiram results in increased expression of CNTRL mRNA | CTD | PMID:38568856 | Cntrl | Rat | titanium dioxide | increases expression | ISO | Cntrl (Mus musculus) | 6480464 | titanium dioxide results in increased expression of CNTRL mRNA | CTD | PMID:29264374 | Cntrl | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of CNTRL mRNA | CTD | PMID:33387578 | Cntrl | Rat | trichostatin A | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of CNTRL mRNA | CTD | PMID:26272509 | Cntrl | Rat | trichostatin A | multiple interactions | ISO | CNTRL (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CNTRL mRNA | CTD | PMID:27188386 | Cntrl | Rat | triphenyl phosphate | affects expression | ISO | CNTRL (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of CNTRL mRNA | CTD | PMID:37042841 | Cntrl | Rat | trovafloxacin | decreases expression | ISO | Cntrl (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of CNTRL mRNA | CTD | PMID:35537566 | Cntrl | Rat | valproic acid | affects expression | ISO | CNTRL (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CNTRL mRNA | CTD | PMID:25979313 | Cntrl | Rat | valproic acid | decreases expression | ISO | CNTRL (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of CNTRL mRNA | CTD | PMID:23179753 more ... | |